JPH0236593B2 - - Google Patents

Info

Publication number
JPH0236593B2
JPH0236593B2 JP59051058A JP5105884A JPH0236593B2 JP H0236593 B2 JPH0236593 B2 JP H0236593B2 JP 59051058 A JP59051058 A JP 59051058A JP 5105884 A JP5105884 A JP 5105884A JP H0236593 B2 JPH0236593 B2 JP H0236593B2
Authority
JP
Japan
Prior art keywords
group
carbon atoms
sup
tetrahydropyran
yloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59051058A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60197667A (ja
Inventor
Nobuyuki Hamanaka
Hideo Takada
Yoshinobu Arai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority to JP59051058A priority Critical patent/JPS60197667A/ja
Priority to US06/712,446 priority patent/US4622410A/en
Priority to DK122085A priority patent/DK122085A/da
Priority to AT85301868T priority patent/ATE34745T1/de
Priority to HU85994A priority patent/HU200173B/hu
Priority to CA000476787A priority patent/CA1250285A/en
Priority to EP85301868A priority patent/EP0156611B1/en
Priority to DE8585301868T priority patent/DE3563050D1/de
Publication of JPS60197667A publication Critical patent/JPS60197667A/ja
Publication of JPH0236593B2 publication Critical patent/JPH0236593B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Furan Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP59051058A 1984-03-19 1984-03-19 ６―ケト―プロスタグランジン類似化合物及びその製造方法 Granted JPS60197667A (ja)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP59051058A JPS60197667A (ja) 1984-03-19 1984-03-19 ６―ケト―プロスタグランジン類似化合物及びその製造方法
US06/712,446 US4622410A (en) 1984-03-19 1985-03-18 Bicyclo[3,3,0]octan-3-ones
DK122085A DK122085A (da) 1984-03-19 1985-03-18 Mellemprodukter til fremstilling af prostaglandinanaloge
AT85301868T ATE34745T1 (de) 1984-03-19 1985-03-18 Zwischenprodukte fuer die herstellung von prostaglandinanalogen.
HU85994A HU200173B (en) 1984-03-19 1985-03-18 Process for producing intermediary products of prostaglandin analogs
CA000476787A CA1250285A (en) 1984-03-19 1985-03-18 Intermediates for the preparation of prostaglandin analogues
EP85301868A EP0156611B1 (en) 1984-03-19 1985-03-18 Intermediates for the preparation of prostaglandin analogues
DE8585301868T DE3563050D1 (en) 1984-03-19 1985-03-18 Intermediates for the preparation of prostaglandin analogues

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59051058A JPS60197667A (ja) 1984-03-19 1984-03-19 ６―ケト―プロスタグランジン類似化合物及びその製造方法

Publications (2)

Publication Number Publication Date
JPS60197667A JPS60197667A (ja) 1985-10-07
JPH0236593B2 true JPH0236593B2 (en:Method) 1990-08-17

Family

ID=12876203

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59051058A Granted JPS60197667A (ja) 1984-03-19 1984-03-19 ６―ケト―プロスタグランジン類似化合物及びその製造方法

Country Status (8)

Country Link
US (1) US4622410A (en:Method)
EP (1) EP0156611B1 (en:Method)
JP (1) JPS60197667A (en:Method)
AT (1) ATE34745T1 (en:Method)
CA (1) CA1250285A (en:Method)
DE (1) DE3563050D1 (en:Method)
DK (1) DK122085A (en:Method)
HU (1) HU200173B (en:Method)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3620442A1 (de) * 1986-06-18 1987-12-23 Merck Patent Gmbh Ketolactone
US5149457A (en) * 1989-06-30 1992-09-22 Cyprus Foote Mineral Company Stable mixed lithium amide reagent compositions
US5196138A (en) * 1989-06-30 1993-03-23 Cyprus Foote Mineral Company Preparation of mixed lithium amide reagents
WO2001046134A1 (en) * 1999-12-22 2001-06-28 Alcon Universal Ltd. 6-KETO PROSTAGLANDIN F1α AND ANALOGS FOR TREATING DRY EYE
US7833995B2 (en) 2003-12-05 2010-11-16 Ono Pharmaceutical Co., Ltd. Blood flow promoters for cauda equina tissues
WO2006129788A1 (ja) 2005-06-03 2006-12-07 Ono Pharmaceutical Co., Ltd. 神経再生および／または保護剤
PT2441760E (pt) 2009-06-10 2014-01-07 Ono Pharmaceutical Co Composto com actividade de contracção muscular do detrusor e actividade de relaxação muscular do esfíncter uretral
RU2658823C2 (ru) 2012-08-31 2018-06-25 Оно Фармасьютикал Ко., Лтд. Аминовая соль и ее кристаллы

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558142A (en) * 1981-03-11 1985-12-10 Hoffmann-La Roche Inc. 7-Fluoro-prostacyclin analogs
US4410710A (en) * 1981-09-25 1983-10-18 Research Foundation Of The City University Of New York Conversion of iridoids to prostaglandins

Also Published As

Publication number Publication date
EP0156611A2 (en) 1985-10-02
EP0156611A3 (en) 1986-04-23
DK122085D0 (da) 1985-03-18
DE3563050D1 (en) 1988-07-07
JPS60197667A (ja) 1985-10-07
EP0156611B1 (en) 1988-06-01
HUT37137A (en) 1985-11-28
ATE34745T1 (de) 1988-06-15
HU200173B (en) 1990-04-28
CA1250285A (en) 1989-02-21
US4622410A (en) 1986-11-11
DK122085A (da) 1985-09-20

Similar Documents

Publication Publication Date Title
US4035414A (en) Prostanoic acid derivatives
US4649156A (en) 6-nitroprostaglandin derivatives
JPH0236593B2 (en:Method)
US4198430A (en) 13,14-Dehydro-11-deoxy-prostaglandis
US4338332A (en) Fluoro-prostaglandins
JPS60169459A (ja) フエノキシプロスタトリエン酸誘導体の製造法
JPS5823393B2 (ja) プロスタグランジンルイジカゴウブツ ノ セイゾウホウホウ
JPS6125010B2 (en:Method)
US4845282A (en) Process for prostaglandin E1 production, and novel delta 7-prostaglandins E and 7-hydroxyprostaglandins E
CH651033A5 (de) Fluorprostacycline.
US4078021A (en) Dimethyl 2-oxo-6-cyanohexyl-phosphonate
US4490548A (en) Enlarged-hetero-ring prostacyclin analogs
US4797506A (en) 6-substituted prostaglandins E1 and process for producing same
JP2839841B2 (ja) プロスタグランジンｅ１ 類の製造法、及びその合成中間体
US4273784A (en) Organic compounds
US4220759A (en) 13,14-Dehydro-11-deoxy-prostaglandins and process for their preparation
US4110341A (en) Dithio prostaglandin derivatives
US4293705A (en) 13,14-Dehydro-11-deoxy-prostaglandins and process for their preparation
CA1154441A (en) Intermediates for prostaglandin analogues
US4414407A (en) Fluoro-prostaglandins and process for their preparation
KR840001722B1 (ko) 프로스타글란딘 유도체의 제조방법
JPH11158120A (ja) シクロペンテン誘導体の製造方法
JPS5814432B2 (ja) １６，１６↓−ジメチル↓−１７↓−オキサプロスタグランジン類
DK146025B (da) Analogifremgangsmaade til fremstilling af trans-delta2-prostaglandinanaloge
JPS6360757B2 (en:Method)