ATE34745T1 - Zwischenprodukte fuer die herstellung von prostaglandinanalogen. - Google Patents
Zwischenprodukte fuer die herstellung von prostaglandinanalogen.Info
- Publication number
- ATE34745T1 ATE34745T1 AT85301868T AT85301868T ATE34745T1 AT E34745 T1 ATE34745 T1 AT E34745T1 AT 85301868 T AT85301868 T AT 85301868T AT 85301868 T AT85301868 T AT 85301868T AT E34745 T1 ATE34745 T1 AT E34745T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- group
- carbon atoms
- sub
- alkyl group
- Prior art date
Links
- 239000013067 intermediate product Substances 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 9
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Furan Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59051058A JPS60197667A (ja) | 1984-03-19 | 1984-03-19 | ６―ケト―プロスタグランジン類似化合物及びその製造方法 |
| EP85301868A EP0156611B1 (de) | 1984-03-19 | 1985-03-18 | Zwischenprodukte für die Herstellung von Prostaglandinanalogen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE34745T1 true ATE34745T1 (de) | 1988-06-15 |
Family
ID=12876203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85301868T ATE34745T1 (de) | 1984-03-19 | 1985-03-18 | Zwischenprodukte fuer die herstellung von prostaglandinanalogen. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4622410A (de) |
| EP (1) | EP0156611B1 (de) |
| JP (1) | JPS60197667A (de) |
| AT (1) | ATE34745T1 (de) |
| CA (1) | CA1250285A (de) |
| DE (1) | DE3563050D1 (de) |
| DK (1) | DK122085A (de) |
| HU (1) | HU200173B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3620442A1 (de) * | 1986-06-18 | 1987-12-23 | Merck Patent Gmbh | Ketolactone |
| US5149457A (en) * | 1989-06-30 | 1992-09-22 | Cyprus Foote Mineral Company | Stable mixed lithium amide reagent compositions |
| US5196138A (en) * | 1989-06-30 | 1993-03-23 | Cyprus Foote Mineral Company | Preparation of mixed lithium amide reagents |
| US6576663B2 (en) | 1999-12-22 | 2003-06-10 | Alcon, Inc. | 6-Keto prostaglandin F1α and analogs for treating dry eye |
| US7833995B2 (en) | 2003-12-05 | 2010-11-16 | Ono Pharmaceutical Co., Ltd. | Blood flow promoters for cauda equina tissues |
| CA2610692C (en) | 2005-06-03 | 2014-11-25 | Ono Pharmaceutical Co., Ltd. | Ep2 agonists which may have an ep3 agonistic effect for regeneration and/or protection of nerves |
| PT2441760E (pt) | 2009-06-10 | 2014-01-07 | Ono Pharmaceutical Co | Composto com actividade de contracção muscular do detrusor e actividade de relaxação muscular do esfíncter uretral |
| CA2882732C (en) | 2012-08-31 | 2021-03-30 | Ono Pharmaceutical Co., Ltd. | A 2-[(2-{(1r,5r)-2-oxo-5-[(1e,4s)-7,8,8-trifluoro-4-hydroxy-4-methyl-1,7-octadiene-1-yl]cyclopentyl}ethyl)thio}-1,3-thiazole-4-carboxylic acid 4-piperidinemethanol salt and crystals thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4558142A (en) * | 1981-03-11 | 1985-12-10 | Hoffmann-La Roche Inc. | 7-Fluoro-prostacyclin analogs |
| US4410710A (en) * | 1981-09-25 | 1983-10-18 | Research Foundation Of The City University Of New York | Conversion of iridoids to prostaglandins |
-
1984
- 1984-03-19 JP JP59051058A patent/JPS60197667A/ja active Granted
-
1985
- 1985-03-18 US US06/712,446 patent/US4622410A/en not_active Expired - Fee Related
- 1985-03-18 CA CA000476787A patent/CA1250285A/en not_active Expired
- 1985-03-18 DK DK122085A patent/DK122085A/da not_active Application Discontinuation
- 1985-03-18 DE DE8585301868T patent/DE3563050D1/de not_active Expired
- 1985-03-18 HU HU85994A patent/HU200173B/hu not_active IP Right Cessation
- 1985-03-18 EP EP85301868A patent/EP0156611B1/de not_active Expired
- 1985-03-18 AT AT85301868T patent/ATE34745T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HU200173B (en) | 1990-04-28 |
| EP0156611A3 (en) | 1986-04-23 |
| DK122085D0 (da) | 1985-03-18 |
| CA1250285A (en) | 1989-02-21 |
| EP0156611A2 (de) | 1985-10-02 |
| EP0156611B1 (de) | 1988-06-01 |
| JPS60197667A (ja) | 1985-10-07 |
| JPH0236593B2 (de) | 1990-08-17 |
| HUT37137A (en) | 1985-11-28 |
| DK122085A (da) | 1985-09-20 |
| US4622410A (en) | 1986-11-11 |
| DE3563050D1 (en) | 1988-07-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4096179A (en) | 13,14-Dihydro-16-phenoxy prostaglandin F1α analogs | |
| KR860009023A (ko) | 치환된 실릴기를 갖는 신규 에테르 화합물의 제조방법 | |
| US4161606A (en) | ω-Aryl-cis-13-inter-oxa-PGA compounds | |
| US4083865A (en) | Inter-oxa-13,14-dihydro-PGD1 compounds | |
| US4097506A (en) | Cis-13,9-deoxy-PGF1 compounds | |
| ATE34745T1 (de) | Zwischenprodukte fuer die herstellung von prostaglandinanalogen. | |
| US4122105A (en) | Cis-4,5-didehydro-12,13(E)didehydro-13,14-dihydro-PGD1 compounds | |
| US4065633A (en) | 2,2-Difluoro-13,14-dihydro-PGA1 analogs | |
| US4065629A (en) | 17-Phenyl-18,19,20-trinor-cis-4,5-didehydro-PGA1 compounds | |
| US4212985A (en) | cis-4,5-Didehydro-16-phenoxy-PGE1 compounds | |
| US3974191A (en) | 16-Fluoro prostaglandin F1 analogs | |
| AU8236387A (en) | Improved keto-reduction of carbacycline intermediates | |
| ES8502675A1 (es) | Un metodo para preparar productos intermedios para la obtencion de 4-fenil-1,3-benzodiazepinas | |
| US4269995A (en) | 19,20-Didehydro-13,14-dihydro-PG2 compounds | |
| US4160102A (en) | ω-Aryl-inter-oxa-9-deoxy-PGD1 compounds | |
| US4081594A (en) | Unsaturated bicyclic lactone intermediates for preparing pgc-type compounds | |
| US3996267A (en) | 3-Oxo phenyl-substituted PGF compounds | |
| US4257981A (en) | 2-Decarboxy-2-aminomethyl-19,20-didehydro-PG2 compounds | |
| US4003946A (en) | 4,5-Cis-didehydro-PGF1 analogs | |
| US4236019A (en) | Esters of prostacyclin-type compounds | |
| US4257982A (en) | 2-Decarboxy-2-aminomethyl-19,20-didehydro-13,14-dihydro-PG2 compounds | |
| US4283350A (en) | 19,20-Didehydro-PG2 amides | |
| US4041066A (en) | 4,5-Cis-didehydro-PGE1 compounds | |
| US4061657A (en) | Process for preparing a 2(R) or 2(S) tricyclic lactone glycol | |
| US4264523A (en) | 19,20-Didehydro-13,14-dihydro-PG1 amides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |