JPH0233717B2 - - Google Patents

Info

Publication number
JPH0233717B2
JPH0233717B2 JP55085994A JP8599480A JPH0233717B2 JP H0233717 B2 JPH0233717 B2 JP H0233717B2 JP 55085994 A JP55085994 A JP 55085994A JP 8599480 A JP8599480 A JP 8599480A JP H0233717 B2 JPH0233717 B2 JP H0233717B2
Authority
JP
Japan
Prior art keywords
borane
complex
amine
water
amine complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP55085994A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5610196A (en
Inventor
Emu Efu Rimu Geirii
Endo Masaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of JPS5610196A publication Critical patent/JPS5610196A/ja
Publication of JPH0233717B2 publication Critical patent/JPH0233717B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP8599480A 1979-07-05 1980-06-26 Manufacture of 77*22aminomethylphenylacetoamido** 33*11carboxymethyltetrazoll55yllthiomethyl** 33cephemm44carboxylic acid Granted JPS5610196A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/054,733 US4243803A (en) 1979-07-05 1979-07-05 Production of 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid

Publications (2)

Publication Number Publication Date
JPS5610196A JPS5610196A (en) 1981-02-02
JPH0233717B2 true JPH0233717B2 (enExample) 1990-07-30

Family

ID=21993156

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8599480A Granted JPS5610196A (en) 1979-07-05 1980-06-26 Manufacture of 77*22aminomethylphenylacetoamido** 33*11carboxymethyltetrazoll55yllthiomethyl** 33cephemm44carboxylic acid

Country Status (5)

Country Link
US (1) US4243803A (enExample)
JP (1) JPS5610196A (enExample)
CA (1) CA1136123A (enExample)
ES (1) ES493079A0 (enExample)
FR (1) FR2460954A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0630976B2 (ja) * 1986-07-31 1994-04-27 凸版印刷株式会社 製本方法
AU2001241042A1 (en) * 2000-03-08 2001-09-17 Takeda Chemical Industries Ltd. Process for the preparation of hydrazine derivatives
CN102898442A (zh) * 2012-10-25 2013-01-30 河南中帅医药科技发展有限公司 头孢雷特的精制方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2860167A (en) * 1953-10-07 1958-11-11 Bokine teialkyl amines
US3035904A (en) * 1953-10-07 1962-05-22 Diesel fuel compositions
US4297489A (en) * 1974-09-03 1981-10-27 Bristol-Myers Company 7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids
JPS525787A (en) * 1975-06-27 1977-01-17 Bristol Myers Co Antiibacterial agent
US4118563A (en) * 1977-11-25 1978-10-03 Bristol-Myers Company Production of 7-(2-aminomethylphenylacetamido-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid

Also Published As

Publication number Publication date
US4243803A (en) 1981-01-06
CA1136123A (en) 1982-11-23
JPS5610196A (en) 1981-02-02
FR2460954A1 (fr) 1981-01-30
ES8107235A1 (es) 1981-10-01
ES493079A0 (es) 1981-10-01
FR2460954B1 (enExample) 1984-02-17

Similar Documents

Publication Publication Date Title
JP4852419B2 (ja) ４−（４−アミノフェニル）−３−モルホリノンの製造方法
JP2013216696A (ja) 触媒性水素転移反応を使用する新規なオピエート還元
JP2003252862A (ja) ４，５−ジアミノ−１−（２’−ヒドロキシエチル）ピラゾール及びその酸付加塩の製造方法
JPH0233717B2 (enExample)
CN115417876B (zh) 一种巴瑞替尼中间体化合物
JPH10503530A (ja) ハロ置換芳香族酸の製造方法
JPH03109336A (ja) １，１，１，２‐テトラフルオロエタンの製造方法
US3928337A (en) Process for the production of cefamandole
JP7217519B2 (ja) ２－オキサゾリジノン類の製造方法
JPH0647568B2 (ja) ２，４‐ジクロロ‐５‐フルオロ安息香酸の製法
JPH08505399A (ja) 芳香族アルデヒドヘのホルミル化方法
US7772441B1 (en) Process for producing 3,4′ dihydroxybenzophenone
JPS5925779B2 (ja) 立体異性脂環ジアミンの異性化法
JPH10330329A (ja) ビス（アミノメチル）シクロヘキサンの異性化方法
JPH02290851A (ja) ２―クロロ―５―アミノメチルーピリジンの製造方法
KR900006208B1 (ko) 신규 염소화 방법
JPH0257531B2 (enExample)
JP3787864B2 (ja) ビスアルキルフェノール系化合物の製造方法
JPS6136244A (ja) ２，４，６−トリフルオロ安息香酸の製造方法
JP3084488B2 (ja) ２−ハロゲノ−４，５−ジフルオロ安息香酸の製造法
JP3787867B2 (ja) モノメチロール化合物の製造方法
JP3787866B2 (ja) ｐ−クレゾールの２核体ジメチロール化合物の製造方法
CN117510352A (zh) 一种d-2,3-二氨基丙酸的合成方法
JPH0460101B2 (enExample)
JP2025524632A (ja) ５－ブロモ－３，４－ジメチルピリジン－２－アミンおよび６－ブロモ－７，８－ジメチル－［１，２，４］トリアゾロ［１，５－ａ］ピリジンの製造方法