JPH0216244B2 - - Google Patents
Info
- Publication number
- JPH0216244B2 JPH0216244B2 JP57172296A JP17229682A JPH0216244B2 JP H0216244 B2 JPH0216244 B2 JP H0216244B2 JP 57172296 A JP57172296 A JP 57172296A JP 17229682 A JP17229682 A JP 17229682A JP H0216244 B2 JPH0216244 B2 JP H0216244B2
- Authority
- JP
- Japan
- Prior art keywords
- calcium carbonate
- calcium
- powder
- product
- amorphous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 152
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 73
- 238000006243 chemical reaction Methods 0.000 claims description 52
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 29
- 238000000034 method Methods 0.000 claims description 17
- 238000010438 heat treatment Methods 0.000 claims description 15
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 14
- 239000001569 carbon dioxide Substances 0.000 claims description 14
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 14
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 13
- 239000000920 calcium hydroxide Substances 0.000 claims description 13
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 12
- -1 calcium halides Chemical class 0.000 claims description 11
- 229940043430 calcium compound Drugs 0.000 claims description 10
- 150000001674 calcium compounds Chemical class 0.000 claims description 10
- 238000004519 manufacturing process Methods 0.000 claims description 8
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 claims description 6
- ZCCIPPOKBCJFDN-UHFFFAOYSA-N calcium nitrate Chemical compound [Ca+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O ZCCIPPOKBCJFDN-UHFFFAOYSA-N 0.000 claims description 6
- 229910052791 calcium Inorganic materials 0.000 claims description 4
- 239000011575 calcium Substances 0.000 claims description 4
- 230000005484 gravity Effects 0.000 claims description 4
- PAWQVTBBRAZDMG-UHFFFAOYSA-N 2-(3-bromo-2-fluorophenyl)acetic acid Chemical compound OC(=O)CC1=CC=CC(Br)=C1F PAWQVTBBRAZDMG-UHFFFAOYSA-N 0.000 claims description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 3
- 235000019270 ammonium chloride Nutrition 0.000 claims description 3
- 239000007864 aqueous solution Substances 0.000 claims description 3
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 claims description 3
- 239000000292 calcium oxide Substances 0.000 claims description 3
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 claims description 3
- USFZMSVCRYTOJT-UHFFFAOYSA-N Ammonium acetate Chemical compound N.CC(O)=O USFZMSVCRYTOJT-UHFFFAOYSA-N 0.000 claims description 2
- 239000005695 Ammonium acetate Substances 0.000 claims description 2
- 238000004438 BET method Methods 0.000 claims description 2
- 235000019257 ammonium acetate Nutrition 0.000 claims description 2
- 229940043376 ammonium acetate Drugs 0.000 claims description 2
- 229910052751 metal Inorganic materials 0.000 claims description 2
- 239000002184 metal Substances 0.000 claims description 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 99
- 235000010216 calcium carbonate Nutrition 0.000 description 72
- 239000000843 powder Substances 0.000 description 52
- 239000000047 product Substances 0.000 description 46
- 238000002441 X-ray diffraction Methods 0.000 description 22
- 239000012730 sustained-release form Substances 0.000 description 22
- 238000013268 sustained release Methods 0.000 description 21
- 238000003756 stirring Methods 0.000 description 19
- 230000000704 physical effect Effects 0.000 description 18
- 239000003205 fragrance Substances 0.000 description 17
- 239000007789 gas Substances 0.000 description 16
- 238000012360 testing method Methods 0.000 description 16
- 239000000725 suspension Substances 0.000 description 15
- 239000013543 active substance Substances 0.000 description 14
- 239000003795 chemical substances by application Substances 0.000 description 14
- 239000013078 crystal Substances 0.000 description 14
- 229910021532 Calcite Inorganic materials 0.000 description 13
- 238000001035 drying Methods 0.000 description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 12
- 235000011116 calcium hydroxide Nutrition 0.000 description 11
- 239000000463 material Substances 0.000 description 11
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 9
- 235000019441 ethanol Nutrition 0.000 description 9
- 239000011521 glass Substances 0.000 description 9
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 9
- 239000000126 substance Substances 0.000 description 9
- 230000000052 comparative effect Effects 0.000 description 8
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 7
- NIQCNGHVCWTJSM-UHFFFAOYSA-N Dimethyl phthalate Chemical compound COC(=O)C1=CC=CC=C1C(=O)OC NIQCNGHVCWTJSM-UHFFFAOYSA-N 0.000 description 6
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 238000012790 confirmation Methods 0.000 description 6
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 6
- 239000002994 raw material Substances 0.000 description 6
- 238000010998 test method Methods 0.000 description 6
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 5
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 5
- 239000006227 byproduct Substances 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 229940041616 menthol Drugs 0.000 description 5
- 239000002904 solvent Substances 0.000 description 5
- 238000000967 suction filtration Methods 0.000 description 5
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 4
- 239000007795 chemical reaction product Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 239000006072 paste Substances 0.000 description 4
- 230000002265 prevention Effects 0.000 description 4
- 239000005871 repellent Substances 0.000 description 4
- 230000002940 repellent Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical compound C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical compound [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 description 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- 241000255925 Diptera Species 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- 239000005792 Geraniol Substances 0.000 description 3
- GLZPCOQZEFWAFX-YFHOEESVSA-N Geraniol Natural products CC(C)=CCC\C(C)=C/CO GLZPCOQZEFWAFX-YFHOEESVSA-N 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- 239000001099 ammonium carbonate Substances 0.000 description 3
- QRUDEWIWKLJBPS-UHFFFAOYSA-N benzotriazole Chemical compound C1=CC=C2N[N][N]C2=C1 QRUDEWIWKLJBPS-UHFFFAOYSA-N 0.000 description 3
- 239000012964 benzotriazole Substances 0.000 description 3
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- FBSAITBEAPNWJG-UHFFFAOYSA-N dimethyl phthalate Natural products CC(=O)OC1=CC=CC=C1OC(C)=O FBSAITBEAPNWJG-UHFFFAOYSA-N 0.000 description 3
- 229960001826 dimethylphthalate Drugs 0.000 description 3
- 239000000975 dye Substances 0.000 description 3
- 239000000945 filler Substances 0.000 description 3
- 229940113087 geraniol Drugs 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- 239000003112 inhibitor Substances 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 229960000907 methylthioninium chloride Drugs 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 230000002688 persistence Effects 0.000 description 3
- 239000000049 pigment Substances 0.000 description 3
- 238000001179 sorption measurement Methods 0.000 description 3
- ULDHMXUKGWMISQ-SECBINFHSA-N (-)-carvone Chemical compound CC(=C)[C@@H]1CC=C(C)C(=O)C1 ULDHMXUKGWMISQ-SECBINFHSA-N 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- WRMNZCZEMHIOCP-UHFFFAOYSA-N 2-phenylethanol Chemical compound OCCC1=CC=CC=C1 WRMNZCZEMHIOCP-UHFFFAOYSA-N 0.000 description 2
- XPCTZQVDEJYUGT-UHFFFAOYSA-N 3-hydroxy-2-methyl-4-pyrone Chemical compound CC=1OC=CC(=O)C=1O XPCTZQVDEJYUGT-UHFFFAOYSA-N 0.000 description 2
- 229910000013 Ammonium bicarbonate Inorganic materials 0.000 description 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
- LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 235000012538 ammonium bicarbonate Nutrition 0.000 description 2
- 238000007664 blowing Methods 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 2
- QMVPMAAFGQKVCJ-UHFFFAOYSA-N citronellol Chemical compound OCCC(C)CCC=C(C)C QMVPMAAFGQKVCJ-UHFFFAOYSA-N 0.000 description 2
- WTWBUQJHJGUZCY-UHFFFAOYSA-N cuminaldehyde Chemical compound CC(C)C1=CC=C(C=O)C=C1 WTWBUQJHJGUZCY-UHFFFAOYSA-N 0.000 description 2
- 230000006866 deterioration Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 229920001971 elastomer Polymers 0.000 description 2
- SHZIWNPUGXLXDT-UHFFFAOYSA-N ethyl hexanoate Chemical compound CCCCCC(=O)OCC SHZIWNPUGXLXDT-UHFFFAOYSA-N 0.000 description 2
- PPXUHEORWJQRHJ-UHFFFAOYSA-N ethyl isovalerate Chemical compound CCOC(=O)CC(C)C PPXUHEORWJQRHJ-UHFFFAOYSA-N 0.000 description 2
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 description 2
- 239000000417 fungicide Substances 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 description 2
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 description 2
- 235000019359 magnesium stearate Nutrition 0.000 description 2
- GVOWHGSUZUUUDR-UHFFFAOYSA-N methyl N-methylanthranilate Chemical compound CNC1=CC=CC=C1C(=O)OC GVOWHGSUZUUUDR-UHFFFAOYSA-N 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- IZUPBVBPLAPZRR-UHFFFAOYSA-N pentachlorophenol Chemical compound OC1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1Cl IZUPBVBPLAPZRR-UHFFFAOYSA-N 0.000 description 2
- MDHYEMXUFSJLGV-UHFFFAOYSA-N phenethyl acetate Chemical compound CC(=O)OCCC1=CC=CC=C1 MDHYEMXUFSJLGV-UHFFFAOYSA-N 0.000 description 2
- ZQBAKBUEJOMQEX-UHFFFAOYSA-N phenyl salicylate Chemical compound OC1=CC=CC=C1C(=O)OC1=CC=CC=C1 ZQBAKBUEJOMQEX-UHFFFAOYSA-N 0.000 description 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 235000017557 sodium bicarbonate Nutrition 0.000 description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 2
- 229910000029 sodium carbonate Inorganic materials 0.000 description 2
- 235000017550 sodium carbonate Nutrition 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 239000000454 talc Substances 0.000 description 2
- 229910052623 talc Inorganic materials 0.000 description 2
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 description 2
- WJCNZQLZVWNLKY-UHFFFAOYSA-N thiabendazole Chemical compound S1C=NC(C=2NC3=CC=CC=C3N=2)=C1 WJCNZQLZVWNLKY-UHFFFAOYSA-N 0.000 description 2
- RUVINXPYWBROJD-ONEGZZNKSA-N trans-anethole Chemical compound COC1=CC=C(\C=C\C)C=C1 RUVINXPYWBROJD-ONEGZZNKSA-N 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- WHOZNOZYMBRCBL-OUKQBFOZSA-N (2E)-2-Tetradecenal Chemical compound CCCCCCCCCCC\C=C\C=O WHOZNOZYMBRCBL-OUKQBFOZSA-N 0.000 description 1
- WJTCHBVEUFDSIK-NWDGAFQWSA-N (2r,5s)-1-benzyl-2,5-dimethylpiperazine Chemical compound C[C@@H]1CN[C@@H](C)CN1CC1=CC=CC=C1 WJTCHBVEUFDSIK-NWDGAFQWSA-N 0.000 description 1
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 description 1
- OOCCDEMITAIZTP-QPJJXVBHSA-N (E)-cinnamyl alcohol Chemical compound OC\C=C\C1=CC=CC=C1 OOCCDEMITAIZTP-QPJJXVBHSA-N 0.000 description 1
- OALYTRUKMRCXNH-UHFFFAOYSA-N (R)- Dihydro-5-pentyl-2(3H)-furanone Natural products CCCCCC1CCC(=O)O1 OALYTRUKMRCXNH-UHFFFAOYSA-N 0.000 description 1
- QMVPMAAFGQKVCJ-SNVBAGLBSA-N (R)-(+)-citronellol Natural products OCC[C@H](C)CCC=C(C)C QMVPMAAFGQKVCJ-SNVBAGLBSA-N 0.000 description 1
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 description 1
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- MVOSYKNQRRHGKX-UHFFFAOYSA-N 11-Undecanolactone Chemical compound O=C1CCCCCCCCCCO1 MVOSYKNQRRHGKX-UHFFFAOYSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- PGYZAKRTYUHXRA-UHFFFAOYSA-N 2,10-dinitro-12h-[1,4]benzothiazino[3,2-b]phenothiazin-3-one Chemical compound S1C2=CC(=O)C([N+]([O-])=O)=CC2=NC2=C1C=C1SC3=CC=C([N+](=O)[O-])C=C3NC1=C2 PGYZAKRTYUHXRA-UHFFFAOYSA-N 0.000 description 1
- ZXDDPOHVAMWLBH-UHFFFAOYSA-N 2,4-Dihydroxybenzophenone Chemical compound OC1=CC(O)=CC=C1C(=O)C1=CC=CC=C1 ZXDDPOHVAMWLBH-UHFFFAOYSA-N 0.000 description 1
- RWLALWYNXFYRGW-UHFFFAOYSA-N 2-Ethyl-1,3-hexanediol Chemical compound CCCC(O)C(CC)CO RWLALWYNXFYRGW-UHFFFAOYSA-N 0.000 description 1
- FLUWAIIVLCVEKF-UHFFFAOYSA-N 2-Methyl-1-phenyl-2-propanyl acetate Chemical compound CC(=O)OC(C)(C)CC1=CC=CC=C1 FLUWAIIVLCVEKF-UHFFFAOYSA-N 0.000 description 1
- RCSBILYQLVXLJG-UHFFFAOYSA-N 2-Propenyl hexanoate Chemical compound CCCCCC(=O)OCC=C RCSBILYQLVXLJG-UHFFFAOYSA-N 0.000 description 1
- UAQFADWTDBIBBZ-UHFFFAOYSA-N 2-[2-(2-naphthalen-2-ylethoxy)ethyl]naphthalene Chemical compound C1=CC=CC2=CC(CCOCCC=3C=C4C=CC=CC4=CC=3)=CC=C21 UAQFADWTDBIBBZ-UHFFFAOYSA-N 0.000 description 1
- MBRHNTMUYWQHMR-UHFFFAOYSA-N 2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one Chemical compound NCCO.ON1C(=O)C=C(C)C=C1C1CCCCC1 MBRHNTMUYWQHMR-UHFFFAOYSA-N 0.000 description 1
- POAOYUHQDCAZBD-UHFFFAOYSA-N 2-butoxyethanol Chemical compound CCCCOCCO POAOYUHQDCAZBD-UHFFFAOYSA-N 0.000 description 1
- RIWRBSMFKVOJMN-UHFFFAOYSA-N 2-methyl-1-phenylpropan-2-ol Chemical compound CC(C)(O)CC1=CC=CC=C1 RIWRBSMFKVOJMN-UHFFFAOYSA-N 0.000 description 1
- HXIQYSLFEXIOAV-UHFFFAOYSA-N 2-tert-butyl-4-(5-tert-butyl-4-hydroxy-2-methylphenyl)sulfanyl-5-methylphenol Chemical compound CC1=CC(O)=C(C(C)(C)C)C=C1SC1=CC(C(C)(C)C)=C(O)C=C1C HXIQYSLFEXIOAV-UHFFFAOYSA-N 0.000 description 1
- DLHQZZUEERVIGQ-UHFFFAOYSA-N 3,7-dimethyl-3-octanol Chemical compound CCC(C)(O)CCCC(C)C DLHQZZUEERVIGQ-UHFFFAOYSA-N 0.000 description 1
- CSDQQAQKBAQLLE-UHFFFAOYSA-N 4-(4-chlorophenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine Chemical compound C1=CC(Cl)=CC=C1C1C(C=CS2)=C2CCN1 CSDQQAQKBAQLLE-UHFFFAOYSA-N 0.000 description 1
- 229910018072 Al 2 O 3 Inorganic materials 0.000 description 1
- PJYULPFAIBMGHC-UHFFFAOYSA-N CCOP(=S)(OCC)OC1=CC=CC(Cl)=C1Cl Chemical compound CCOP(=S)(OCC)OC1=CC=CC(Cl)=C1Cl PJYULPFAIBMGHC-UHFFFAOYSA-N 0.000 description 1
- UNMYWSMUMWPJLR-UHFFFAOYSA-L Calcium iodide Chemical compound [Ca+2].[I-].[I-] UNMYWSMUMWPJLR-UHFFFAOYSA-L 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 description 1
- 235000001258 Cinchona calisaya Nutrition 0.000 description 1
- WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 description 1
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 1
- JVSOZLOGYGPXLB-UHFFFAOYSA-M ClC1=C([O-])C=C(C(=C1)Cl)Cl.C(CCCCCCCCCCC)[N+](C)(C)C Chemical compound ClC1=C([O-])C=C(C(=C1)Cl)Cl.C(CCCCCCCCCCC)[N+](C)(C)C JVSOZLOGYGPXLB-UHFFFAOYSA-M 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 229910016523 CuKa Inorganic materials 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- GHKOFFNLGXMVNJ-UHFFFAOYSA-N Didodecyl thiobispropanoate Chemical compound CCCCCCCCCCCCOC(=O)CCSCCC(=O)OCCCCCCCCCCCC GHKOFFNLGXMVNJ-UHFFFAOYSA-N 0.000 description 1
- HHJIUUAMYGBVSD-YTFFSALGSA-N Diflucortolone valerate Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@H](C(=O)COC(=O)CCCC)[C@@]2(C)C[C@@H]1O HHJIUUAMYGBVSD-YTFFSALGSA-N 0.000 description 1
- 239000003508 Dilauryl thiodipropionate Substances 0.000 description 1
- WWJJVKAEQGGYHJ-UHFFFAOYSA-M Dimethylthiophosphate Chemical compound COP([O-])(=S)OC WWJJVKAEQGGYHJ-UHFFFAOYSA-M 0.000 description 1
- 241000402754 Erythranthe moschata Species 0.000 description 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- 239000005770 Eugenol Substances 0.000 description 1
- 239000004606 Fillers/Extenders Substances 0.000 description 1
- 235000000177 Indigofera tinctoria Nutrition 0.000 description 1
- 235000019738 Limestone Nutrition 0.000 description 1
- HYMLWHLQFGRFIY-UHFFFAOYSA-N Maltol Natural products CC1OC=CC(=O)C1=O HYMLWHLQFGRFIY-UHFFFAOYSA-N 0.000 description 1
- NWBJYWHLCVSVIJ-UHFFFAOYSA-N N-benzyladenine Chemical compound N=1C=NC=2NC=NC=2C=1NCC1=CC=CC=C1 NWBJYWHLCVSVIJ-UHFFFAOYSA-N 0.000 description 1
- FTXUQEKXCJSWMO-UHFFFAOYSA-N Nonanolactone Chemical compound O=C1CCCCCCCCO1 FTXUQEKXCJSWMO-UHFFFAOYSA-N 0.000 description 1
- 239000004264 Petrolatum Substances 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 1
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 description 1
- 239000004288 Sodium dehydroacetate Substances 0.000 description 1
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 description 1
- 235000011941 Tilia x europaea Nutrition 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 229930003316 Vitamin D Natural products 0.000 description 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 229930003448 Vitamin K Natural products 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- 239000003905 agrochemical Substances 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- OOCCDEMITAIZTP-UHFFFAOYSA-N allylic benzylic alcohol Natural products OCC=CC1=CC=CC=C1 OOCCDEMITAIZTP-UHFFFAOYSA-N 0.000 description 1
- HMKKIXGYKWDQSV-KAMYIIQDSA-N alpha-Amylcinnamaldehyde Chemical compound CCCCC\C(C=O)=C\C1=CC=CC=C1 HMKKIXGYKWDQSV-KAMYIIQDSA-N 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- QUMXDOLUJCHOAY-UHFFFAOYSA-N alpha-methylbenzyl acetate Natural products CC(=O)OC(C)C1=CC=CC=C1 QUMXDOLUJCHOAY-UHFFFAOYSA-N 0.000 description 1
- WUOACPNHFRMFPN-UHFFFAOYSA-N alpha-terpineol Chemical compound CC1=CCC(C(C)(C)O)CC1 WUOACPNHFRMFPN-UHFFFAOYSA-N 0.000 description 1
- 235000012501 ammonium carbonate Nutrition 0.000 description 1
- 229940011037 anethole Drugs 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 239000003429 antifungal agent Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- JGQFVRIQXUFPAH-UHFFFAOYSA-N beta-citronellol Natural products OCCC(C)CCCC(C)=C JGQFVRIQXUFPAH-UHFFFAOYSA-N 0.000 description 1
- 235000010290 biphenyl Nutrition 0.000 description 1
- 239000004305 biphenyl Substances 0.000 description 1
- 125000006267 biphenyl group Chemical group 0.000 description 1
- 238000001354 calcination Methods 0.000 description 1
- 229910001622 calcium bromide Inorganic materials 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- WGEFECGEFUFIQW-UHFFFAOYSA-L calcium dibromide Chemical compound [Ca+2].[Br-].[Br-] WGEFECGEFUFIQW-UHFFFAOYSA-L 0.000 description 1
- 229940046413 calcium iodide Drugs 0.000 description 1
- 229910001640 calcium iodide Inorganic materials 0.000 description 1
- 239000006013 carbendazim Substances 0.000 description 1
- TWFZGCMQGLPBSX-UHFFFAOYSA-N carbendazim Chemical compound C1=CC=C2NC(NC(=O)OC)=NC2=C1 TWFZGCMQGLPBSX-UHFFFAOYSA-N 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 235000011089 carbon dioxide Nutrition 0.000 description 1
- 235000014171 carbonated beverage Nutrition 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
- ULDHMXUKGWMISQ-UHFFFAOYSA-N carvone Natural products CC(=C)C1CC=C(C)C(=O)C1 ULDHMXUKGWMISQ-UHFFFAOYSA-N 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- LFHISGNCFUNFFM-UHFFFAOYSA-N chloropicrin Chemical compound [O-][N+](=O)C(Cl)(Cl)Cl LFHISGNCFUNFFM-UHFFFAOYSA-N 0.000 description 1
- 229960004375 ciclopirox olamine Drugs 0.000 description 1
- LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 description 1
- 229940043350 citral Drugs 0.000 description 1
- 235000015165 citric acid Nutrition 0.000 description 1
- 235000000484 citronellol Nutrition 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- IQFVPQOLBLOTPF-HKXUKFGYSA-L congo red Chemical compound [Na+].[Na+].C1=CC=CC2=C(N)C(/N=N/C3=CC=C(C=C3)C3=CC=C(C=C3)/N=N/C3=C(C4=CC=CC=C4C(=C3)S([O-])(=O)=O)N)=CC(S([O-])(=O)=O)=C21 IQFVPQOLBLOTPF-HKXUKFGYSA-L 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- ZXJXZNDDNMQXFV-UHFFFAOYSA-M crystal violet Chemical compound [Cl-].C1=CC(N(C)C)=CC=C1[C+](C=1C=CC(=CC=1)N(C)C)C1=CC=C(N(C)C)C=C1 ZXJXZNDDNMQXFV-UHFFFAOYSA-M 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- SQIFACVGCPWBQZ-UHFFFAOYSA-N delta-terpineol Natural products CC(C)(O)C1CCC(=C)CC1 SQIFACVGCPWBQZ-UHFFFAOYSA-N 0.000 description 1
- 235000019304 dilauryl thiodipropionate Nutrition 0.000 description 1
- 229940095104 dimethyl benzyl carbinyl acetate Drugs 0.000 description 1
- 238000011549 displacement method Methods 0.000 description 1
- 238000004043 dyeing Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- XYIBRDXRRQCHLP-UHFFFAOYSA-N ethyl acetoacetate Chemical compound CCOC(=O)CC(C)=O XYIBRDXRRQCHLP-UHFFFAOYSA-N 0.000 description 1
- 229960002217 eugenol Drugs 0.000 description 1
- CKSJXOVLXUMMFF-UHFFFAOYSA-N exalamide Chemical compound CCCCCCOC1=CC=CC=C1C(N)=O CKSJXOVLXUMMFF-UHFFFAOYSA-N 0.000 description 1
- 229950010333 exalamide Drugs 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- 229940042902 flumethasone pivalate Drugs 0.000 description 1
- JWRMHDSINXPDHB-OJAGFMMFSA-N flumethasone pivalate Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)COC(=O)C(C)(C)C)(O)[C@@]2(C)C[C@@H]1O JWRMHDSINXPDHB-OJAGFMMFSA-N 0.000 description 1
- 239000004088 foaming agent Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 239000005452 food preservative Substances 0.000 description 1
- 235000019249 food preservative Nutrition 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 239000010440 gypsum Substances 0.000 description 1
- 229910052602 gypsum Inorganic materials 0.000 description 1
- WPFVBOQKRVRMJB-UHFFFAOYSA-N hydroxycitronellal Chemical compound O=CCC(C)CCCC(C)(C)O WPFVBOQKRVRMJB-UHFFFAOYSA-N 0.000 description 1
- 230000002267 hypothalamic effect Effects 0.000 description 1
- 229940097275 indigo Drugs 0.000 description 1
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 description 1
- 239000000976 ink Substances 0.000 description 1
- 239000000077 insect repellent Substances 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- UFHLMYOGRXOCSL-UHFFFAOYSA-N isoprothiolane Chemical compound CC(C)OC(=O)C(C(=O)OC(C)C)=C1SCCS1 UFHLMYOGRXOCSL-UHFFFAOYSA-N 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004571 lime Substances 0.000 description 1
- 239000006028 limestone Substances 0.000 description 1
- 235000001510 limonene Nutrition 0.000 description 1
- 229940087305 limonene Drugs 0.000 description 1
- 229930007744 linalool Natural products 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 229940043353 maltol Drugs 0.000 description 1
- 238000010907 mechanical stirring Methods 0.000 description 1
- DWLVWMUCHSLGSU-UHFFFAOYSA-M n,n-dimethylcarbamate Chemical compound CN(C)C([O-])=O DWLVWMUCHSLGSU-UHFFFAOYSA-M 0.000 description 1
- PDDANVVLWYOEPS-UHFFFAOYSA-N nitrous acid;n-propan-2-ylpropan-2-amine Chemical compound [O-]N=O.CC(C)[NH2+]C(C)C PDDANVVLWYOEPS-UHFFFAOYSA-N 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- YYZUSRORWSJGET-UHFFFAOYSA-N octanoic acid ethyl ester Natural products CCCCCCCC(=O)OCC YYZUSRORWSJGET-UHFFFAOYSA-N 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- RUVINXPYWBROJD-UHFFFAOYSA-N para-methoxyphenyl Natural products COC1=CC=C(C=CC)C=C1 RUVINXPYWBROJD-UHFFFAOYSA-N 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 229940044654 phenolsulfonic acid Drugs 0.000 description 1
- 229960000969 phenyl salicylate Drugs 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 1
- KNCYXPMJDCCGSJ-UHFFFAOYSA-N piperidine-2,6-dione Chemical compound O=C1CCCC(=O)N1 KNCYXPMJDCCGSJ-UHFFFAOYSA-N 0.000 description 1
- 239000005648 plant growth regulator Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 235000011181 potassium carbonates Nutrition 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 229960000948 quinine Drugs 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- PYWVYCXTNDRMGF-UHFFFAOYSA-N rhodamine B Chemical compound [Cl-].C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=CC=C1C(O)=O PYWVYCXTNDRMGF-UHFFFAOYSA-N 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 235000019204 saccharin Nutrition 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- WKEDVNSFRWHDNR-UHFFFAOYSA-N salicylanilide Chemical compound OC1=CC=CC=C1C(=O)NC1=CC=CC=C1 WKEDVNSFRWHDNR-UHFFFAOYSA-N 0.000 description 1
- 229950000975 salicylanilide Drugs 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 235000019259 sodium dehydroacetate Nutrition 0.000 description 1
- 229940079839 sodium dehydroacetate Drugs 0.000 description 1
- JXKPEJDQGNYQSM-UHFFFAOYSA-M sodium propionate Chemical compound [Na+].CCC([O-])=O JXKPEJDQGNYQSM-UHFFFAOYSA-M 0.000 description 1
- 239000004324 sodium propionate Substances 0.000 description 1
- 235000010334 sodium propionate Nutrition 0.000 description 1
- 229960003212 sodium propionate Drugs 0.000 description 1
- DSOWAKKSGYUMTF-GZOLSCHFSA-M sodium;(1e)-1-(6-methyl-2,4-dioxopyran-3-ylidene)ethanolate Chemical compound [Na+].C\C([O-])=C1/C(=O)OC(C)=CC1=O DSOWAKKSGYUMTF-GZOLSCHFSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 235000010356 sorbitol Nutrition 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 229940013618 stevioside Drugs 0.000 description 1
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 description 1
- 235000019202 steviosides Nutrition 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 229940116411 terpineol Drugs 0.000 description 1
- 230000008542 thermal sensitivity Effects 0.000 description 1
- 239000004308 thiabendazole Substances 0.000 description 1
- 235000010296 thiabendazole Nutrition 0.000 description 1
- 229960004546 thiabendazole Drugs 0.000 description 1
- NDLIRBZKZSDGSO-UHFFFAOYSA-N tosyl azide Chemical compound CC1=CC=C(S(=O)(=O)[N-][N+]#N)C=C1 NDLIRBZKZSDGSO-UHFFFAOYSA-N 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- DZJZYOVDFNKBIH-UHFFFAOYSA-M trimethylsulfanium;nitrite Chemical compound [O-]N=O.C[S+](C)C DZJZYOVDFNKBIH-UHFFFAOYSA-M 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
- 235000012141 vanillin Nutrition 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
- 239000002912 waste gas Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F11/00—Compounds of calcium, strontium, or barium
- C01F11/18—Carbonates
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F11/00—Compounds of calcium, strontium, or barium
- C01F11/18—Carbonates
- C01F11/184—Preparation of calcium carbonate by carbonation of solutions based on non-aqueous solvents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Geology (AREA)
- Inorganic Chemistry (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
Description
ç£æ¥äžã®å©çšåé
æ¬çºæã¯ãã¢ã¢ã«ãã¢ã¹çé
žã«ã«ã·ãŠã ã®è£œé
æ¹æ³ã«é¢ããã åŸæ¥ã®æè¡ãšãã®åé¡ç¹ æ¬çºæè ã¯ãäžèšã®ãããªåŸæ¥æè¡ã®åé¡ç¹ã«
éã¿ãŠãçµæ¶æ§é äžå æ¹æ¶ç³»ã®ã«ã«ãµã€ããææ¹
æ¶ç³»ã®ã¢ã©ãŽãã€ãåã³æ¬å æ¹æ¶ç³»ã®ããã©ã€ã
ã®äžçš®ã®å質ç°åãããç¥ãããŠããããã®ãã¡
ã«ã«ãµã€ãçµæ¶äœãæãå®å®ã§ãããã©ã€ããã¢
ã©ãŽãã€ãçµæ¶äœã¯ãå ç±ã磚ç ãªã©ã®ç©ççåŠ
çã«ããäžè¬ã«ã«ã«ãµã€ãçµæ¶äœã«å€åãããšã
ãããŠããããŸãçé žã«ã«ã·ãŠã ã¯ãäžèšäžçš®ã®
çµæ¶äœã®ä»ã«ãç¡å®åœ¢ããšãåŸãããšã極ãçšã«
å ±åãããŠãããç³èãšç³ç°ç¬¬94å·ç¬¬39é ïŒ1968
幎ïŒãJ.Appl.Chem.第17å·»ã第185é ïŒ1967ïŒãã
å³ã¡ä¹çæç®ã«ã¯ã«ã«ãµã€ãçµæ¶ã®çé žã«ã«ã·ãŠ
ã ã磚ç ãããšçµæ¶æ§é ã厩å£ããŠã¢ã¢ã«ãã¢ã¹
ã®ç¶æ ã«ãªãããšåã³æ°Žé žåã«ã«ã·ãŠã ç²äœãäœ
湿床ç°å¢äžã«äºé žåççŽ ã¬ã¹ã«ããæ°çžçé žåã
ããšã¢ã¢ã«ãã¢ã¹ãªçé žã«ã«ã·ãŠã ãåŸãããã
ãšãå ±åãããŠãããããããªããä¹çæç®ã«ç€º
ãããã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã¯ãéåžžäžæ
çã«çæããããã®ã«ãšã©ãŸããäžå®å®ã§ããã
ãã«ã«ã«ãµã€ãçµæ¶ã«å€åãããã®çæã®ç¢ºèªã
å°é£ã§ãããåã¯å®å®ã«åãåºãåŸãªãããŸãæ
è¿ãæ°Žé žåã«ã«ã·ãŠã ã庶ç³ãªã©ã®æ°Žæº¶æ¶²äžã§ã
15â以äžã®äœæž©äžã«äºé žåççŽ ã¬ã¹ãçšããŠçé ž
åããçæç©ãåŽé§ä¹Ÿç¥åã¯é å¿åé¢ã«ããè±æ°Ž
ããæŽã«ç空也ç¥ãªã©ã«ããååŠççµåæ°Žã®éã
äžå®ã«ããŠåãåºãããšã«ããã¢ã¢ã«ãã¢ã¹çé ž
ã«ã«ã·ãŠã ãå®å®ããŠåŸãæ¹æ³ãææ¡ããããç¹
éæ56â124368å·å ¬å ±ããããããªãããã®æ¹æ³
ã«ããåŸãããçé žã«ã«ã·ãŠã ã¯ãçé žé£²æã®ç
é žæåå°å ¥å€ãšããŠå©çšããããã®ã§ããããã
èªäœåº¶ç³çãå«æããŠç¡å®åœ¢ãä¿æããŠããããŸ
ãååŠçã«çµåããæ°ŽãïŒãïŒïŒ å«æããæ¥æ¬è¬
å±æ¹ãé£åæ·»å ç©å ¬å®æžçã«èŠå®ãããçé žã«ã«
ã·ãŠã ã®ç¯å²ã«å å«ãããªãã äžæ¹çé žã«ã«ã·ãŠã ã¯çœè²åºŠã®é«ãããšãç¡æ¯
ã§ããããšãæ¯èŒçå®äŸ¡ãªããšãåçš®ç²åºŠã®ãã®
ã容æã«åŸãããããšãªã©ããããŽã ããã©ã¹ã
ãã¯çšã®å å¡«å€ãå¡æãã€ã³ãçšã®äœè³ªé¡æãçŽ
ãã蟌ã¿çšã®å¡«æãçŽã³ãŒãçšé¡æãå»è¬ãå粧
åãé£åã蟲æ¥çšãªã©ã®æ·»å å€ãšããŠåºã䜿çšã
ããããããã®çšéã«å¿ããç²åŸã圢ç¶ãè¡šé¢æ§
質ãªã©ãæãããã®ã補é ãåžè²©ãããŠãããã
ä¹çåžè²©åã¯ã»ãšãã©ã«ã«ãµã€ãçµæ¶ã®ãã®ã§ã
ããã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã¯ã該ã«ã«ãµã€
ãååã³ãã®ä»ã®çµæ¶æ§çé žã«ã«ã·ãŠã ã®åé§ç©
質çãªãã®ãšèãããããããããå®å®ã«è£œé æ¡
åã§ããã°ãåŸæ¥å ¬ç¥ã®çé žã«ã«ã·ãŠã ã®å¹ åºã
çšéãšå ±ã«ã該ã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®ç¹
ç°æ§ãå©çšããŠãäŸãã°æŽ»æ§ãªåžçå€ãæ¯éã®å°
ããå å¡«å€ãéææ§é¡æçã®æ°ããçšéã«æå¹ã«
çšããããæããããã®éçºãæåŸ ãããèŠæã
ããŠããã æ¬çºæè ãã¯æ¯ããçŸç¶ã«éã¿ãæ¯çã§èŠæã
ããŠããã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®è£œé ãå¿
çšæè¡ã«ã€ãéæç 究ãéããçµæãã¢ã«ã³ãŒã«
åªäœç³»å ã§ã®çé žååå¿ãè¡ãªãæã«ã¯ææã®ã¢
ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã容æäžã€å®å®ã«è£œé
ã§ããæ¯ãããŠåŸãããã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·
ãŠã ã¯ãããç¹æã®æ§è³ªãæ§ç¶ãæãããããã®
æ§è³ªãå©çšããŠãåçš®ã®æ®æ£æ§ç©è³ªã®æ®æ£é床ã
調ç¯ããåŸæŸæ§åºå€ãšããŠæçšã§ããããšãèŠã
åºããã æ¬çºæã¯ããã®ãããªæ°èŠãªç¥èŠã«åºããŠå®æ
ããããã®ã§ããã å³ã¡ãæ¬çºæã¯ãäžèšã®ã¢ã¢ã«ãã¢ã¹çé žã«ã«
ã·ãŠã ã®è£œé æ¹æ³ãæäŸãããã®ã§ããïŒ ã«ã«ã·ãŠã ååç©ãã¢ã«ã³ãŒã«åªäœç³»å ã§çé ž
ååå¿ãããŠçæ¯é1.6ã2.5ãå±æç1.45ã1.57ã
BETæ³ã«ããæ¯è¡šé¢ç©20ã600m2ïŒïœåã³10ïœïŒ
100mlH2O氎溶液ã®PH6.0ã8.0ãæãç¡å®åœ¢ã§ã
ãã200âãïŒæéã®ãªãŒãã³å ç±ã«ããå®å®ã§
ããçé žã«ã«ã·ãŠã ãåŸãããšãç¹åŸŽãšããã¢ã¢
ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®è£œé æ¹æ³ã æ¬çºææ¹æ³ã«ããåŸãããã¢ã¢ã«ãã¢ã¹çé žã«
ã«ã·ãŠã ïŒä»¥äžç¹ã«å¿ èŠã§ãªãéãåã«æ¬çºæã¢
ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ãšããïŒïŒžç·åæåæ
ã®çµæå šãããŒã¯ãèªãåŸãã1.45ã1.57ã®ç¯å²
ã«åäžã®å±æçã瀺ããç¡å®åœ¢ïŒã¢ã¢ã«ãã¢ã¹ïŒ
ã§ããããšããã®æ倧ã®ç¹åŸŽãšããã該ã¢ã¢ã«ã
ã¢ã¹çé žã«ã«ã·ãŠã ã®ç©ççæ§è³ªããå ¬ç¥ã®çµæ¶
æ§çé žã«ã«ã·ãŠã ãšå¯Ÿæ¯ããŠç€ºãã°ãäžèšç¬¬ïŒè¡š
ã®éãã§ãããæ確ã«çžç°ããããšãå€ãã
æ¹æ³ã«é¢ããã åŸæ¥ã®æè¡ãšãã®åé¡ç¹ æ¬çºæè ã¯ãäžèšã®ãããªåŸæ¥æè¡ã®åé¡ç¹ã«
éã¿ãŠãçµæ¶æ§é äžå æ¹æ¶ç³»ã®ã«ã«ãµã€ããææ¹
æ¶ç³»ã®ã¢ã©ãŽãã€ãåã³æ¬å æ¹æ¶ç³»ã®ããã©ã€ã
ã®äžçš®ã®å質ç°åãããç¥ãããŠããããã®ãã¡
ã«ã«ãµã€ãçµæ¶äœãæãå®å®ã§ãããã©ã€ããã¢
ã©ãŽãã€ãçµæ¶äœã¯ãå ç±ã磚ç ãªã©ã®ç©ççåŠ
çã«ããäžè¬ã«ã«ã«ãµã€ãçµæ¶äœã«å€åãããšã
ãããŠããããŸãçé žã«ã«ã·ãŠã ã¯ãäžèšäžçš®ã®
çµæ¶äœã®ä»ã«ãç¡å®åœ¢ããšãåŸãããšã極ãçšã«
å ±åãããŠãããç³èãšç³ç°ç¬¬94å·ç¬¬39é ïŒ1968
幎ïŒãJ.Appl.Chem.第17å·»ã第185é ïŒ1967ïŒãã
å³ã¡ä¹çæç®ã«ã¯ã«ã«ãµã€ãçµæ¶ã®çé žã«ã«ã·ãŠ
ã ã磚ç ãããšçµæ¶æ§é ã厩å£ããŠã¢ã¢ã«ãã¢ã¹
ã®ç¶æ ã«ãªãããšåã³æ°Žé žåã«ã«ã·ãŠã ç²äœãäœ
湿床ç°å¢äžã«äºé žåççŽ ã¬ã¹ã«ããæ°çžçé žåã
ããšã¢ã¢ã«ãã¢ã¹ãªçé žã«ã«ã·ãŠã ãåŸãããã
ãšãå ±åãããŠãããããããªããä¹çæç®ã«ç€º
ãããã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã¯ãéåžžäžæ
çã«çæããããã®ã«ãšã©ãŸããäžå®å®ã§ããã
ãã«ã«ã«ãµã€ãçµæ¶ã«å€åãããã®çæã®ç¢ºèªã
å°é£ã§ãããåã¯å®å®ã«åãåºãåŸãªãããŸãæ
è¿ãæ°Žé žåã«ã«ã·ãŠã ã庶ç³ãªã©ã®æ°Žæº¶æ¶²äžã§ã
15â以äžã®äœæž©äžã«äºé žåççŽ ã¬ã¹ãçšããŠçé ž
åããçæç©ãåŽé§ä¹Ÿç¥åã¯é å¿åé¢ã«ããè±æ°Ž
ããæŽã«ç空也ç¥ãªã©ã«ããååŠççµåæ°Žã®éã
äžå®ã«ããŠåãåºãããšã«ããã¢ã¢ã«ãã¢ã¹çé ž
ã«ã«ã·ãŠã ãå®å®ããŠåŸãæ¹æ³ãææ¡ããããç¹
éæ56â124368å·å ¬å ±ããããããªãããã®æ¹æ³
ã«ããåŸãããçé žã«ã«ã·ãŠã ã¯ãçé žé£²æã®ç
é žæåå°å ¥å€ãšããŠå©çšããããã®ã§ããããã
èªäœåº¶ç³çãå«æããŠç¡å®åœ¢ãä¿æããŠããããŸ
ãååŠçã«çµåããæ°ŽãïŒãïŒïŒ å«æããæ¥æ¬è¬
å±æ¹ãé£åæ·»å ç©å ¬å®æžçã«èŠå®ãããçé žã«ã«
ã·ãŠã ã®ç¯å²ã«å å«ãããªãã äžæ¹çé žã«ã«ã·ãŠã ã¯çœè²åºŠã®é«ãããšãç¡æ¯
ã§ããããšãæ¯èŒçå®äŸ¡ãªããšãåçš®ç²åºŠã®ãã®
ã容æã«åŸãããããšãªã©ããããŽã ããã©ã¹ã
ãã¯çšã®å å¡«å€ãå¡æãã€ã³ãçšã®äœè³ªé¡æãçŽ
ãã蟌ã¿çšã®å¡«æãçŽã³ãŒãçšé¡æãå»è¬ãå粧
åãé£åã蟲æ¥çšãªã©ã®æ·»å å€ãšããŠåºã䜿çšã
ããããããã®çšéã«å¿ããç²åŸã圢ç¶ãè¡šé¢æ§
質ãªã©ãæãããã®ã補é ãåžè²©ãããŠãããã
ä¹çåžè²©åã¯ã»ãšãã©ã«ã«ãµã€ãçµæ¶ã®ãã®ã§ã
ããã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã¯ã該ã«ã«ãµã€
ãååã³ãã®ä»ã®çµæ¶æ§çé žã«ã«ã·ãŠã ã®åé§ç©
質çãªãã®ãšèãããããããããå®å®ã«è£œé æ¡
åã§ããã°ãåŸæ¥å ¬ç¥ã®çé žã«ã«ã·ãŠã ã®å¹ åºã
çšéãšå ±ã«ã該ã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®ç¹
ç°æ§ãå©çšããŠãäŸãã°æŽ»æ§ãªåžçå€ãæ¯éã®å°
ããå å¡«å€ãéææ§é¡æçã®æ°ããçšéã«æå¹ã«
çšããããæããããã®éçºãæåŸ ãããèŠæã
ããŠããã æ¬çºæè ãã¯æ¯ããçŸç¶ã«éã¿ãæ¯çã§èŠæã
ããŠããã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®è£œé ãå¿
çšæè¡ã«ã€ãéæç 究ãéããçµæãã¢ã«ã³ãŒã«
åªäœç³»å ã§ã®çé žååå¿ãè¡ãªãæã«ã¯ææã®ã¢
ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã容æäžã€å®å®ã«è£œé
ã§ããæ¯ãããŠåŸãããã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·
ãŠã ã¯ãããç¹æã®æ§è³ªãæ§ç¶ãæãããããã®
æ§è³ªãå©çšããŠãåçš®ã®æ®æ£æ§ç©è³ªã®æ®æ£é床ã
調ç¯ããåŸæŸæ§åºå€ãšããŠæçšã§ããããšãèŠã
åºããã æ¬çºæã¯ããã®ãããªæ°èŠãªç¥èŠã«åºããŠå®æ
ããããã®ã§ããã å³ã¡ãæ¬çºæã¯ãäžèšã®ã¢ã¢ã«ãã¢ã¹çé žã«ã«
ã·ãŠã ã®è£œé æ¹æ³ãæäŸãããã®ã§ããïŒ ã«ã«ã·ãŠã ååç©ãã¢ã«ã³ãŒã«åªäœç³»å ã§çé ž
ååå¿ãããŠçæ¯é1.6ã2.5ãå±æç1.45ã1.57ã
BETæ³ã«ããæ¯è¡šé¢ç©20ã600m2ïŒïœåã³10ïœïŒ
100mlH2O氎溶液ã®PH6.0ã8.0ãæãç¡å®åœ¢ã§ã
ãã200âãïŒæéã®ãªãŒãã³å ç±ã«ããå®å®ã§
ããçé žã«ã«ã·ãŠã ãåŸãããšãç¹åŸŽãšããã¢ã¢
ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®è£œé æ¹æ³ã æ¬çºææ¹æ³ã«ããåŸãããã¢ã¢ã«ãã¢ã¹çé žã«
ã«ã·ãŠã ïŒä»¥äžç¹ã«å¿ èŠã§ãªãéãåã«æ¬çºæã¢
ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ãšããïŒïŒžç·åæåæ
ã®çµæå šãããŒã¯ãèªãåŸãã1.45ã1.57ã®ç¯å²
ã«åäžã®å±æçã瀺ããç¡å®åœ¢ïŒã¢ã¢ã«ãã¢ã¹ïŒ
ã§ããããšããã®æ倧ã®ç¹åŸŽãšããã該ã¢ã¢ã«ã
ã¢ã¹çé žã«ã«ã·ãŠã ã®ç©ççæ§è³ªããå ¬ç¥ã®çµæ¶
æ§çé žã«ã«ã·ãŠã ãšå¯Ÿæ¯ããŠç€ºãã°ãäžèšç¬¬ïŒè¡š
ã®éãã§ãããæ確ã«çžç°ããããšãå€ãã
ãè¡šã
äœã第ïŒè¡šã«ãããåç©ççæ§è³ªã¯ã次ã®æ¹æ³
ã«ãã枬å®ãããã®ã§ãããä¹çæ¹æ³ã¯æ¬æ现æž
ãéããŠåãã§ããã çæ¯éïŒãã¯ãã¡ãŒã¿ïŒæ¯éã³ãïŒãçšããŠæ¶²
äœçœ®ææ³ã«ããæ±ããã å±æçïŒã¢ããå±æèšã«ãã枬å®ããå±æçæ¢
ç¥ã®æ¶²äœã«è©Šæã浞挬ããŠæ±ããã PHïŒè©Šæ10ïœã容é100mlã®ç¡¬è³ªäžè§ãã©ã¹ã³
ã«å ¥ããæ°ãã調補ããã€ãªã³äº€æçŽæ°Ž
100mlãå ãããŽã æ ããã10ç§éæ¿ãã
ãµããŸããåŸïŒæéæŸçœ®ããå床軜ããµã
ãŸããŠå®¹é100mlã®ããŒã«ãŒã«ç§»ãããã
ã¬ã©ã¹é»æ¥µPHã¡ãŒã¿ãŒã«ãã枬å®ããã BETæ¯è¡šé¢ç©ïŒãã€ã¯ãã¡ãªãã€ãã¯ã¹ç€Ÿè£œ
N2ã¬ã¹åžçæ³ã«ããBETæ¯è¡šé¢ç©èªå枬
å®è£ 眮ã«ãã枬å®ããã 圢 ç¶ïŒæ¥ç«è£œäœæ補é»åé¡åŸ®é¡ïŒåç2000ã
20000åïŒã«ãã芳å¯ããã ãŸãæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã¯ãåžž
æž©äœæ¹¿åºŠäžå¯éæ¡ä»¶äžã«è²¯èµããå Žåé·æéïŒå°
ãªããšãïŒã±æïŒç¡å®åœ¢ç¶æ åã³äžèšç©ççæ§è³ª
ãä¿æãããã®å®å®æ§ã¯ãšã¢ãŒãªãŒãã³äžã§200
âãïŒæéå ç±ã«ãã€ãŠãå®è³ªçã«æãªãããã
400âã®å ç±ïŒãã®éã®å ç±æžéã¯ïŒïŒ 以äžã§ã
ãïŒåã¯æ°Žã®ååšã«ããçµæ¶æ§çé žã«ã«ã·ãŠã ã«
å€æ ããã æŽã«æ¬çºæçé žã«ã«ã·ãŠã ã¯ããã®ç¹æã®æ§è³ª
ãšããŠäŸãã°éŠæçã®éåžžã®æ¡ä»¶äžã«å€§æ°äžã«æ®
çºåã¯æè¯ããæ®æ£æ§ç©è³ªãåžçä¿æããããã
å ç±ãå æ°Žãªã©ã®å€çæ¡ä»¶ãå ããããšã«ããäž
èšåžçä¿æããç©è³ªããäžèšå€çæ¡ä»¶ã«å¿ããé©
床ã®æŸåºé床ã§æŸåºããæ§è³ªãå ·åãããåŸã€ãŠ
ããã¯äžèšæ®æ£æ§ç©è³ªã®åŸæŸäœåºå€ãšããŠæçšã§
ãããæ¬çºæã¯ãããåŸæŸäœããæäŸãããã®ã§
ããã 以äžæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®è£œé
æ³ã«ã€ã詳述ããã æ¬çºæçé žã«ã«ã·ãŠã ã¯ãåæã«ã«ã·ãŠã åå
ç©ãææ©åªäœç³»å ã§çé žååå¿ãããããšã«ãã
補é ããããåæãšããŠçšããããã«ã«ã·ãŠã å
åç©ã«ã¯ãé žåã«ã«ã·ãŠã ãæ°Žé žåã«ã«ã·ãŠã ã
éå±ã«ã«ã·ãŠã ãæ°ŽçŽ åã«ã«ã·ãŠã ãå¡©åã«ã«ã·
ãŠã ãèåã«ã«ã·ãŠã ããšãŠåã«ã«ã·ãŠã åã³ç¡
é žã«ã«ã·ãŠã ãå«ãŸããããŸãææ©åªäœãšããŠ
ã¯ãççŽ æ°ïŒä»¥äžã®ïŒäŸ¡ãïŒäŸ¡åã³ïŒäŸ¡ã¢ã«ã³ãŒ
ã«ã䜿çšãããïŒä»¥äžç¹ã«å¿ èŠã§ãªãéãããã
ã¢ã«ã³ãŒã«ãåã«ææ©åªäœãšããïŒä¹çã®ãã¡ã§
ç¹ã«å¥œãŸãããã®ãšããŠã¯ãã¡ãã«ã¢ã«ã³ãŒã«ã
ãšãã«ã¢ã«ã³ãŒã«ããããã«ã¢ã«ã³ãŒã«ãããã«
ã¢ã«ã³ãŒã«ããšãã¬ã³ã°ãªã³ãŒã«ãã°ãªã»ãªã³ãª
ã©ãäŸç€ºã§ãããä¹çã¯ïŒçš®åç¬ã§ãïŒçš®ä»¥äžæ··
åããŠã䜿çšããããšãã§ãããäžèšææ©åªäœã¯
ãŸãïŒå®¹éïŒ æªæºã®æ°Žãå«ãã§ããŠãããããã®
æ§ãªå«æ°Žã¢ã«ã³ãŒã«ãçšããå Žåãåæ§ã«æ¬çºæ
ææã®ã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ãååŸã§ã
ãã æ¬çºæã®çé žååå¿ã¯ãäºé žåççŽ åã¯çé žå¡©
ååç©ãçšããŠå®æœããããçšããããäºé žåç
çŽ ã¯æ°äœã§ããå¿ èŠã¯ãªããåºäœïŒãã©ã€ã¢ã€
ã¹ïŒã§ãã€ãŠããããäžè¬ã«ã¯äŸãã°ç³ç°ç³çŒæ
æã«çºçããå»ã¬ã¹ããåŸãããæ¿åºŠ30容éïŒ å
åŸã®äºé žåççŽ ã¬ã¹ã䜿çšã§ããããŸãçé žå¡©å
åç©ãšããŠã¯ãäŸãã°çé žãããªãŠã ãçé žæ°ŽçŽ
ãããªãŠã ãçé žã«ãªãŠã ãçé žã¢ã³ã¢ããŠã ã
çé žæ°ŽçŽ ã¢ã³ã¢ããŠã çãäŸç€ºã§ãããäžèšçé ž
ååå¿ã¯éåžžåæã«ã«ã·ãŠã ååç©ãææ©åªäœã«
溶解ä¹è³æžæ¿ããã液äžã«ãäºé žåççŽ ãå¹ã蟌
ããåã¯çé žå¡©ååç©ãæ¹æäžã«æ·»å åã¯æ·»å åŸ
æ¹ææ··åããããšã«ããè¡ãªããããäºé žåççŽ
ã®å¹ã蟌ã¿ã«ããå Žåããã®ã¬ã¹æ¹æã®ã¿ã§åå¿
ç³»å ãå ååäžãšãªãå Žåãããããéåžžæ©æ¢°ç
æ¹ææäœãæ¡çšããã®ã奜ãŸãããçé žååå¿ã®
枩床ã¯ãçšããææ©åªäœã®æ²žç¹ä»¥äžã§ããã°ç¹ã«
å¶éãããªãããéåžžçŽ45â以äžã奜ãŸããã¯ïŒ
ã45âã®ç¯å²å ãšããããåæã«ã«ã·ãŠã åå
ç©ãææ©åªäœåã³çé žåå€ã®äœ¿çšå²åã¯ãé©å®ã«
決å®ããããšãã§ãããéåžžææ©åªäœïŒåœãå
æã«ã«ã·ãŠã ååç©ãçŽïŒã¢ã«ä»¥äžãäžè¬ã«çŽ
0.05ãïŒã¢ã«ã®ç¯å²ã§çšããçé žåå€ã¯åæã«å¯Ÿ
ãå°ãªããšãçè«åœéãšãªãéã§çšããã®ãæãŸ
ããã ãŸãæ¬çºæã®äžèšçé žååå¿ã¯ãåå¿ç³»å ã«ç¡
é žã¢ã³ã¢ããŠã ãé ¢é žã¢ã³ã¢ããŠã ãå¡©åã¢ã³ã¢
ããŠã çãååšãããããšã«ãããåå¿ãä¿é²ã§
ããå Žåããããä¹çåå¿ä¿é²å€ãšããŠçšããã
ãè©Šè¬ã¯ãéåžžåæã«ã«ã·ãŠã ååç©ã®çŽ0.05ã
20ééïŒ ãšãªãéã§åå¿ç³»å ã«ååšãããããšã
ã§ããã äžèšçé žååå¿ã®çµç¹ã¯ãçé žåå€ãšããŠäºé ž
åççŽ ãçšããå Žåãçé žååå¿ç³»ã®ãµã³ããªã³
ã°æ¶²ãæ°Žã«æžæ¿ãããŠããã®PHãæ±ããããšã«ã
ã決å®ããããéåžžäžèšæžæ¿æ¶²ïŒ10ïœïŒ100mlæ°Ž
ãšããŠïŒã®PHãã»ãŒïŒãïŒãšãªãç¹ãçµç¹ãšãã
ãããŸãçé žåå€ãšããŠçé žå¡©ååç©ãçšããå Ž
åãäžèšåå¿çµç¹ã¯ãç³»å ã«åå¿çæç©ããã¯ã
æåºããªããªãæç¹ãšããã®ããããããããŠæ¬
çºæã®ã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ãå«æããæ
æ©åªäœæžæ¿æ¶²ãååŸã§ããã æ¬çºæã®ã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã¯ãäžèš
æžæ¿æ¶²ã®ãŸãŸåã¯ãããé©åœã«ããŒã¹ãåããŠã
ãŒã¹ã圢æ ã§ææçšéã«å©çšããããšãã§ãã
ããéåžžçé žã«ã«ã·ãŠã ã®åªäœæžæ¿æ¶²ãéããŠ
ææ©åªäœãé€å»ãããããåžžæ³ã«åŸãå ç±ä¹Ÿç¥ã
ç²ç ãããæã¯äžèšæžæ¿æ¶²ãçŽæ¥ä¹Ÿç¥ããããšã«
ãããç²æ«è£œåãšããŠåé¢ååŸããããå°çé žå
ã®æ¡ä»¶ã«ãã€ãŠã¯ãç®çãšããã¢ã¢ã«ãã¢ã¹çé ž
ã«ã«ã·ãŠã ã®ä»ã«å¯çç©ãçæããå¯èœæ§ããã
ãããã®å¯çç©ã¯å¿ èŠã«å¿ããŠéåžžã®æŽæµæäœã
æœãããšã«ããé€å»ã§ããã æ¬çºæã¯äžèšã®åŠãããŠåŸãããæžæ¿æ¶²åœ¢æ ä¹
è³ããŒã¹ã圢æ åã³ç²æ«åœ¢æ ã®ã¢ã¢ã«ãã¢ã¹çé ž
ã«ã«ã·ãŠã åã³ä¹çãåºå€ãšããŠå«æããé€æŸäœ
ãæäŸãããã®ã§ãããæ¬çºææ¹æ³ã«ããåŸãã
ãã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ãåºå€ãšããåŸæŸ
äœïŒä»¥äžåã«æ¬çºæåŸæŸäœãšããïŒã¯ãéåžžã®æ¡
件äžã«å€§æ°äžã«æ®çºä¹è³æè¯ããç©è³ªæã¯æ°Žåå
ã¯ç±ãä»ããŠåŸæŸäœå€éšã«æ¡æ£ããç©è³ªã§ããã
éåžžã®éŠæãææã蟲è¬ãå»è¬ãåå³ç©è³ªãé²é»Ž
å€çãå å«ããããä¹çç©è³ªïŒä»¥äžãäœçšç©è³ªã
ãšåŒã¶ïŒã®å ·äœäŸãšããŠã¯ãäžèšåååç©ãäŸç€º
ã§ããã (1) éŠæ ã¢ã»ãé ¢é žãšãã«ãã¢ãããŒã«ãã¢ãã«ã·ã³ã
ããã¯ã¢ã«ããããã€ãœåèé žãšãã«ããŠã³ãã«
ã©ã¯ãã³ããããªã³ããšãã¬ã³ãã©ã·ã¬ãŒãããª
ã€ã²ããŒã«ãã«ããªã«é žãšãã«ãã«ããã³é žã¢ãª
ã«ãã«ããã³é žãšãã«ãïœâã«ã«ãã³ãã¯ãã³ã¢
ã«ããããã±ã€ç®ã¢ã«ã³ãŒã«ãã²ã©ããªãŒã«ãé ¢
é žãžã¡ãã«ãã³ãžã«ã«ã«ããã«ãã·ãã©ãŒã«ãã·
ãããããŒã«ããžããããžã€ã¹ã¢ã³ããžã¡ãã«ã
ã³ãžã«ã«ã«ãããŒã«ãããã©ããããªãããŒã«ã
ãã«ãããªãŒã«ãβâãããã«ãšãã«ãšãŒãã«ã
ããã©ã¯ãã³ãããããã·ã·ãããã©ãŒã«ãβâ
ããšãã«ãšãã«ã¢ã«ã³ãŒã«ãããšãã«é ¢é žãšã
ã«ããã³ãžã«ã¢ã«ã³ãŒã«ããã«ããŒã«ãã ã¹ã¯ã
ïœâã¡ãã«ã¢ã³ã¹ã©ãã«é žã¡ãã«ãã¡ã³ããŒã«ã
ãšãã³ããªãããŒã«ããªã¢ãã³ç (2) ææ ã¡ãã¬ã³ãã«ãŒãã¡ãã«ãã€ãªã¬ããããµã«ã
ã¢ãŒãã©ãã¯ãã€ã³ãžãŽãã³ã³ãŽãŒã¬ãããã³ã
ãã³ãã©ãŠã³ããã¯ã»ãªã³ããªã¬ã³ãžããã°ã
ã·ã³ãããŒããã³ç (3) èŸ²è¬ ãžã¡ãã«ãã¿ã¬ãŒããïŒâãšãã«âïŒïŒïŒâã
ããµã³ãžãªãŒã«ãã€ã³ããã³ããžã¡ãã«ã«ãŒãã¡
ã€ããã€ã«ã¬ããªã³ãPCPå€ïŒãã³ã¿ã¯ãã«ã
ãšããŒã«ïŒãMEPå€ïŒãžã¡ãã«ããªãã¹ããšãŒ
ãïŒãECPå€ïŒãžãšãã«ãžã¯ãã«ããšãã«ããªã
ã¹ããšãŒãïŒãã¯ãããã¯ãªã³ããããè³ããã
ã¿ãªã³ããã©ãžã¯ãã«ãã³ãŒã³ãã¡ã¿ã¢ã«ããã (4) å»è¬ ãã¿ãã³ïŒ¡ããã¿ãã³ïŒ€ããã¿ãã³ïŒ¥ããã¿ã
ã³ïŒ«ãããšããŒã«ã¹ã«ãã³é žãããšãã«ãã³ããŒ
ã«ãåèé žãžãã«ã³ã«ããã³ãããã«é žãã«ã¡ã¿
ãŸã³ããšããµã©ãããã·ã¯ãããã¯ã¹ãªã©ãã³ã
ã·ãã«ãã³ (5) åå³ç©è³ª ã¯ãšã³é žãä¹³é žããªã³ãŽé žããµãã«ãªã³ãã¹ã
ããªãµã€ãããœã«ãããŒã«ããã«ã·ã³ããããŒ
ããã«ããšã€ã³ (6) é²ã°ãå€ ãµãªãã«ã¢ããªããïŒâ2â²âãžãªãã·âïŒïŒ
5â²âãžã¯ãããžããšãã«ã¡ã¿ã³ããªã«ãããšã
ã«ãããšããŒã«ããžããšãã«ããã¢ãã³ããŸãŒã« (7) ãã®ä» æ°åæ§é²éå€ïŒäºç¡é žããªã¡ãã«ã¹ã«ãããŠ
ã ãäºç¡é žãžã€ãœãããã«ã¢ã³ã¢ããŠã ã
ïŒïŒïŒïŒïŒãã³ãŸããªã¢ãŸãŒã« 殺èå€ïŒã€ãœããããªã©ã³å€ãã«ã«ãã³ããŸãŒ
ã«å€ æ€ç©çé·èª¿æŽå€ïŒããŒãšå€ãïŒâïŒïŒ®âãã³ãž
ã«ïŒã¢ããããªã³ããã·ãã¬ãªã³ããªã©ã
ã³å€ãïŒïŒ®ïŒïŒ®âããªã¡ãã«âïŒâã¡ã
ã«âïŒâïŒïŒïŒïŒïŒïŒâããªã¡ãã«âïŒâ
ã·ã¯ãããã»ã³âïŒâã€ã«ïŒâïŒâããã
ãã«ã¢ã³ã¢ããŠã é£åä¿åæïŒããããé ¢é žãããªãŠã ãããã
ãªã³é žãããªãŠã ãã©ãŠãªã«ããªã¡ãã«ã¢
ã³ã¢ããŠã âïŒïŒïŒïŒïŒâããªã¯ãã«ããš
ãããµã€ã é žåé²æ¢å€ïŒïŒïŒ4â²âããªãã¹âïŒïŒâã¡ãã«
âïŒâïœããã«ããšããŒã«ïŒããžã©ãŠãªã«
ããªãžããããªããŒãããã³ã¿ãšãªã¹ãªã
ã«âããã©ãã¹ãïŒâïŒïŒïŒïŒâãžãŒã¿ãŒ
ã·ã€ãªããã«âïŒâããããã·ããšããŒ
ã«ïŒããããªããŒã 玫å€ç·åžåå€ïŒïŒïŒïŒâãžããããã·ãã³ãŸã
ãšãã³ãããšãã«ãµãªã·ã¬ãŒããïŒâ
ïŒ2â²âããããã·â5â²âã¡ã«ããšãã«ïŒâ
ãã³ãŸããªã¢ãŸãŒã« ããºãå¿é¿å€ïŒÎ²âãïŒâïŒïŒïŒïŒâãžã¡ãã«
âïŒâOXOã»ã·ã¯ãããã·ã«ïŒâïŒâã
ãããã·ãšãã«ãã°ã«ã¿ãªãã 液äœçºæ³¡å€ïŒãã©ã»ãã«ãšã³ã»ã¹ã«ããã«ã¢ãž
ã äžèšåçš®äœçšç©è³ªãåžçä¿æããæ¬çºæåŸæŸäœ
ã¯ãæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®è£œé ãš
åæã«åã¯äºã該çé žã«ã«ã·ãŠã ã補é åŸããã«
äœçšç©è³ªãåžçãããããšã«ãã補é ããããšã
ã§ããããã®æ¹æ³ã®ä»£è¡šäŸãšããŠã¯ä»¥äžã®ãã®ã
äŸç€ºã§ããã (1) æ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®è£œé
æãçšããææ©åªäœäžã«ææã®äœçšç©è³ªãæ·»å
ååšãããäžè¿°ããçé žååå¿ãè¡ãªãã (2) åèšããçé žååå¿ã«ããåŸãããã¢ã¢ã«ã
ã¢ã¹çé žã«ã«ã·ãŠã ãå«æããææ©åªäœæžæ¿æ¶²
äžã«ãææã®äœçšç©è³ªãæ·»å ããã (3) æ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®ç²æ«è£œ
åã«ãäºãé©åœãªæº¶åªã«æº¶è§£ãããäœçšç©è³ªã®
液ãåŽé§ããããæã¯é©åœãªæº¶åªäžã«äžèšç²æ«
補åãšäœçšç©è³ªãšã浞挬ãã次ãã§æº¶åªãé€å»
ïŒä¹Ÿç¥ïŒããã äžèšãããã®æ¹æ³ãæ¡çšããå Žåããäœçšç©è³ª
ã®äœ¿çšéã¯ã該äœçšç©è³ªã®çš®é¡ãåŸãããåŸæŸäœ
ã«èŠæãããçšéä¹è³è©²åŸæŸäœããã®äœçšç©è³ªã®
æ®æ£é床ïŒæç¶æéïŒçã«å¿ããŠé©å®ã«æ±ºå®ã
ããæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®é£œååž
çéãäžéãšããŠéåžžçšããäœçšç©è³ªã¯ã»ãŒå®å š
ã«åžçä¿æããããäžè¬ã«ãã®åžçä¿æéã¯ãã¢
ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ééãåºæºãšããŠ
0.001ã2.0åééçšåºŠãšããã®ã奜ãŸããããŸã
äžèš(3)ã«ç€ºãæ¹æ³ã«ãããŠçšãã溶åªãšããŠã¯ã
äŸãã°ã¡ã¿ããŒã«ããšã¿ããŒã«ãã¢ã»ãã³ãé ¢é ž
ãšãã«ãããã«ã»ã«ãœã«ãããã«ãšã³ããããµ
ã³ãåå¡©åççŽ ãã¯ãããã«ã çãäŸç€ºã§ããã
也ç¥æ段ãšããŠã¯å溶åªã®æ²žç¹åã¯ãã以äžã®æž©
床ã«å ç±ããããæžå§äžã«ç±é¢šä¹Ÿç¥ãããã也ç¥
空æ°ã«ããé颚也ç¥ããçã®æ段ãæ¡çšããããš
ãã§ããã ããããŠåŸãããæ¬çºæåŸæŸäœã¯ãé·æã«äºã€
ãŠäœçšç©è³ªã®å€è³ªãå£åçãé²æ¢ã§ãããã®ã§ã
ããäžã€è©²äœçšç©è³ªãé©åœãªæŸåºé床ããã€ãŠå®¹
æã«æŸåºãäŸçµŠã§ãããã®ã§ãããäœçšç©è³ªæ¬æ¥
ã®äœçšãé·æã«äºã€ãŠæå¹ã«æç¶çºçŸãåŸããã®
ã§ããã 以äžå®æœäŸåã³æ¯èŒäŸãæããæ¬çºæãæŽã«è©³
è¿°ããã å®æœäŸ ïŒ æ¹ææ©åã³ã¬ã¹å°å ¥ç®¡ãåããã¬ã©ã¹å®¹åšïŒå®¹
éïŒïŒã«ãæ°Žé žåã«ã«ã·ãŠã ç²æ«300ïœåã³ã¡
ã¿ããŒã«ïŒãå ãã18âïŒåžžæž©ïŒã§ã30容éïŒ
ã®äºé žåççŽ ã¬ã¹ãå§å ¥ããçé žååå¿ãè¡ãªã€
ãã çé žååå¿éäžã«ãããŠéæãµã³ããªã³ã°ãè¡
ãªããæ¡åãµã³ããªã³ã°ãæ°Žã«æžæ¿ããã10ïŒ æž
æ¿æ¶²ã®PHãïŒã«ãªã€ãæç¹ã§åå¿ïŒæé«æž©åºŠ27
âïŒãçµäºããã åŸãããçæç©ãåžåŒéããŠã¡ã¿ããŒã«é€å»
ãã次ã«ç©ºæ°åŸªç°åŒå ç±ä¹Ÿç¥æ©ã«ãã110âã§ïŒ
æé也ç¥ãã也ç¥ç©ãç²ç ããŠæ¬çºæã¢ã¢ã«ãã¢
ã¹çé žã«ã«ã·ãŠã ç²æ«380ïœãåŸãã ãã®ç²æ«ã®ïŒžç·åæåæå³ïŒCuKaãNiãã€ã«
ã¿ãŒïŒã¯ç¬¬ïŒå³ã«ç€ºãéãã§ãããå šãããŒã¯ã¯
èªãããããã¢ã¢ã«ãã¢ã¹ã§ããããšãå€ãããŸ
ããã®ç²æ«ã¯æ¥æ¬è¬å±æ¹ã®çé žã«ã«ã·ãŠã 確èªè©Š
éšæ¹æ³ã«åŸãè©Šéšããçµæçé žã«ã«ã·ãŠã ã§ãã
ãšç¢ºèªãããããã®ç©ççæ§è³ªã第ïŒè¡šã«ç€ºãã
æŽã«ãã®ç²æ«ããªãŒãã³äž200âã§ïŒæéä¿æåŸ
åæ§ã«ïŒžç·åæåæãè¡ãªã€ãçµæã¯ç¬¬ïŒå³ã«ç€º
ãéãã§ãããå šãããŒã¯ã¯èªããããå®å®ã§ã
ã€ããå°ãªãŒãã³äžã§400âã§ïŒæéçŒæåŸã®ïŒž
ç·åæå³ã¯ç¬¬ïŒå³ã«ç€ºãéãã§ãããã«ã«ãµã€ã
ã«å€åããŠããããšã確èªãããã ãŸãäžèšã§åŸãã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ç²
æ«ã®ç€ºå·®ç±ã»ç±å€©ç§€æž¬å®å³ã第ïŒå³ã«ç€ºãã該å³
ãã400âãŸã§ã®å ç±æžéã¯1.0ïŒ ä»¥äžã§ããããš
ãå€ããå°è©²å³ã«ããã枬å®æ¡ä»¶ã¯æ¬¡ã®éãã§ã
ããå³äžïŒã¯ç€ºå·®ç±æ²ç·ïŒDTAïŒãã(2)ã¯å ç±
æžéæ²ç·ïŒTGïŒãããŸã(3)ã¯æž©åºŠæ²ç·ïŒâïŒã
瀺ãã è©Šææ¡åéïŒ11mg ææž©é床ïŒ10âïŒå 瀺差ç±æ床ïŒÂ±100ÎŒV æšæºè©ŠæïŒÎ±âAl2O3 å®æœäŸ ïŒ æ¹ææ©åã³ã¬ã¹å°å ¥ç®¡ãåããã¬ã©ã¹å®¹åšïŒå®¹
éïŒïŒã«ãé žåã«ã«ã·ãŠã ç²æ«ïŒ200ã¡ãã·ãŠ
ãã¹åïŒ28ïœåã³ã¡ã¿ããŒã«500mlãå ããæ¹æ
ããªãã25âïŒåžžæž©ïŒã§ãäºã空æ°ã«ããæ¿åºŠã
30容éïŒ ã«èª¿è£œããäºé žåççŽ ã¬ã¹ãéããçé ž
ååå¿ïŒæé«æž©åºŠ32âïŒãè¡ãªããå®æœäŸïŒãšå
æ§ã®æ¹æ³ã«ããåå¿çµäºæç¹ãå€å®ããã ããããŠåŸãããçæç©ããåžåŒéã«ããã¡
ã¿ããŒã«ãé€å»ããæ®æž£ã也ç¥åšã«ãŠ110âã§ïŒ
æé也ç¥ããç²ç ããŠæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«
ã«ã·ãŠã ç²æ«45ïœãåŸãã åŸãããç²æ«ã¯ãç·åæåæã®çµæ第ïŒå³ãš
åæ§ã«å šãããŒã¯ãèªãããããæ¥æ¬è¬å±æ¹ã®ç
é žã«ã«ã·ãŠã 確èªè©Šéšæ¹æ³ã«ããçé žã«ã«ã·ãŠã
ã§ãããšèªããããããŸããªãŒãã³äž200âã§ïŒ
æéä¿æåŸãç·åæåæã§å šãããŒã¯ãèªãã
ããå®å®ã§ãã€ãããã®ãã®ã®ç©ççæ§è³ªã¯ç¬¬ïŒ
è¡šã«ç€ºãéãã§ããã æ¯èŒäŸ ïŒ å®æœäŸïŒãšåäžã®åå¿å®¹åšã«ã40ééïŒ æ¿åºŠã®
æ°Žé žåã«ã«ã·ãŠã æ°Žæžæ¿ç©ïŒç³ç°ä¹³ã¹ã©ãªãŒïŒ
250ïœåã³ã¡ã¿ããŒã«ïŒãå ãïŒãã®ç³»ã®æ°Žé ž
åã«ã«ã·ãŠã ã®ã¡ã¿ããŒã«ã«å¯Ÿããæ¿åºŠã¯ïŒã¢
ã«ïŒã¡ã¿ããŒã«ã§ãããã¡ã¿ããŒã«ã«å¯Ÿããæ°Ž
åéã¯10容éïŒ ã§ããïŒãããã«30容éïŒ ã®äºé ž
åççŽ ã¬ã¹ãéããŠçé žååå¿ãè¡ãªããå®æœäŸ
ïŒãšåäžæ¹æ³ã«ããçé žååå¿çµäºç¹ãå€å®ãã
åŸãããçæç©ãåžåŒéãããšãããæ®ãã©ã
ã¹ãŠãçŽãééãããééããçæç©ïŒã¡ã¿ã
ãŒã«æžæ¿ç©ïŒã«ã€ããã¡ã¿ããŒã«ãæ®çºãããŠåŸ
ãç²æ«ã¯ãç·åæåæã®çµæçµæ¶è³ªïŒããã©ã€
ãåïŒçé žã«ã«ã·ãŠã ã§ãããšç¢ºèªãããããã®
ãã®ã®ç©ççæ§è³ªã第ïŒè¡šã«ç€ºãã å®æœäŸ ïŒ æ¹ææ©åã³ã¬ã¹å°å ¥ç®¡ãåããã¬ã©ã¹å®¹åšïŒå®¹
éïŒïŒã«ãæ°Žé žåã«ã«ã·ãŠã ç²æ«74ïœåã³ã¡ã¿
ããŒã«500mlãå ããæ¹æããªãã30容éïŒ ã®äº
é žåççŽ ã¬ã¹ãïŒïŒåã®é床ã§éããŠçé žåå
å¿ãè¡ãªããå®æœäŸïŒãšåäžæ¹æ³ã«ããå€å®ãã
çé žååå¿çµäºæç¹ïŒçŽ1.5æéåŸïŒã§åŸããã
çæç©ã®ã¡ã¿ããŒã«æžæ¿ç©ãåžåŒéããŠã¡ã¿ã
ãŒã«ãåé¢ããæ®æž£ã也ç¥æ©ã«ãŠ110âã§ïŒæé
也ç¥ããŠ91ïœã®ç²æ«ãåŸãã ãã®ç²æ«ã¯ïŒžç·åæåæã®çµæ第ïŒå³ãšåæ§ã«
å šãããŒã¯ã瀺ããã¢ã¢ã«ãã¢ã¹ã§ããããŸãæ¥
æ¬è¬å±æ¹ã«ããè©Šéšã®çµæçé žã«ã«ã·ãŠã ã§ãã
ãšç¢ºèªãããããŸãããã¯ãªãŒãã³äž200âãïŒ
æéä¿æåŸãç·åæåæã§å šãããŒã¯ã瀺ãã
å®å®ã§ãã€ãããã®ãã®ã®ç©ççæ§è³ªã第ïŒè¡šã«
瀺ãã å®æœäŸ ïŒ å®æœäŸïŒã«ãããŠãã¡ã¿ããŒã«500mlããã¡ã¿
ããŒã«490mlåã³æ°Ž10mlïŒã¡ã¿ããŒã«ã«å¯ŸãïŒå®¹
éïŒ ïŒã«ä»£ããåæ§ã«ããŠçé žååå¿ãè¡ãªãã
æ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ç²æ«84ïœãåŸ
ãããã®ãã®ã¯å®å®ïŒ200âãïŒæéãªãŒãã³å
ç±ïŒã§ããããã®ç©ççæ§è³ªã¯ç¬¬ïŒè¡šã«ç€ºãéã
ã§ããã æ¯èŒäŸ ïŒ å®æœäŸïŒã«ãããŠãã¡ã¿ããŒã«500mlãã¡ã¿ã
ãŒã«450mlåã³æ°Ž50mlïŒã¡ã¿ããŒã«ã«å¯Ÿã10容é
ïŒ ïŒã«ä»£ããåæ§ã«çé žååå¿ãè¡ãªããåæ§ã«
åå¿çµäºæç¹ãæ±ããã該åå¿çµäºæç¹ã«ããã
çæç©ã¯åžåŒéã®éçŽãééãå¥äžå¯èœã§
ãã€ãããã液ãå ç±ä¹Ÿç¥ããŠã¡ã¿ããŒã«ãæ®
çºããããã也ç¥éäžã§æ¢ã«çµæ¶è³ªïŒããã©ã€ã
åïŒçé žã«ã«ã·ãŠã ã«ãªã€ãŠããããšãç·åæ
åæã§ç¢ºèªãããããã®ãã®ã®ç©ççæ§è³ªã第ïŒ
è¡šã«ç€ºãã å®æœäŸ ïŒ æ¹ææ©ããã³ã¬ã¹å°å ¥ç®¡ãåããã¬ã©ã¹å®¹åš
ïŒå®¹é500mlïŒã«éå±ã«ã«ã·ãŠã 110ïœããã³ã¡ã¿
ããŒã«250mlãå ããæ¹æããªãã25âïŒåžžæž©ïŒ
ã§ãäºã空æ°ã«ããæ¿åºŠã30容éïŒ ã«èª¿æŽããäº
é žåççŽ ã¬ã¹ãéããçé žååå¿ãè¡ãªãå®æœäŸ
ïŒãšåæ§ã®æ¹æ³ã«ããåå¿çµäºæç¹ãå€å®ããã ããããŠåŸãããçæç©ããåžåŒéã«ããã¡
ã¿ããŒã«ãé€å»ããæ®æž£ã也ç¥åšã«ãŠ110âã§ïŒ
æé也ç¥ããŠãæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠ
ã ç²æ«20ïœãåŸãã åŸãããç²æ«ã¯ãç·åæåæã®çµæ第ïŒå³ãš
åæ§ã«å šãããŒã¯ãèªãããããæ¥æ¬è¬å±æ¹ã®ç
é žã«ã«ã·ãŠã 確èªè©Šéšæ¹æ³ã«ããçé žã«ã«ã·ãŠã
ã§ãããšèªããããããŸããªãŒãã³äž200âã§ïŒ
æéä¿æåŸãç·åæåæã§å šãããŒã¯ãèªãã
ããå®å®ã§ãã€ãããã®ãã®ã®ç©ççæ§è³ªã¯ç¬¬ïŒ
è¡šã«ç€ºãéãã§ããã å®æœäŸ ïŒ å®æœäŸïŒã«ãããŠã¡ã¿ããŒã«500mlããïœâã
ããã«ã¢ã«ã³ãŒã«500mlã«ä»£ããåæ§ã«ããŠçé ž
ååå¿ãè¡ãªããå®æœäŸïŒãšåæ§ã«ããŠåå¿çµäº
æç¹ãæ±ãããšããçŽïŒæéãèŠãããåŸããã
çæç©ãå®æœäŸïŒãšåæ§ã«ããŠåŠçããŠæ¬çºæã¢
ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ç²æ«90ïœãåŸãããã®
ãã®ã®ç©ççæ§è³ªã第ïŒè¡šã«ç€ºãã å®æœäŸ ïŒ å®æœäŸïŒã«ãããŠã¡ã¿ããŒã«500mlãïœâãã
ãã«ã¢ã«ã³ãŒã«500mlãšãããŸãçé žååå¿ç³»å
ã«åå¿ä¿é²å€ãšããŠå¡©åã¢ã³ã¢ããŠã 0.4ïœãæ·»
å ããåæ§ã«ããŠçé žååå¿ãè¡ãªããåå¿çµäº
æç¹ãå€å®ãããšãããçŽ1.5æéãèŠãããåŸ
ãããçæç©ãåæ§ã«åŠçããŠåŸãããã¢ã¢ã«ã
ã¢ã¹çé žã«ã«ã·ãŠã ç²æ«ïŒåé91ïœïŒã®ç©ççæ§
質ã第ïŒè¡šã«ç€ºãã å®æœäŸ ïŒ å®æœäŸïŒã«ãããŠãã¡ã¿ããŒã«500mlã«ä»£ãïœ
âããã«ã¢ã«ã³ãŒã«500mlãçšããåæ§ã«çé žå
åå¿ãããåå¿çµäºç¹ãæ±ãããã®æç¹ã«ããã
çæç©ïŒïœâããã«ã¢ã«ã³ãŒã«æžæ¿ç©ïŒãå ç±ä¹Ÿ
ç¥ããŠãæ¬çºæã®ã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ç²
æ«82ïœãåŸãããã®ãã®ã¯å®å®ïŒ200âãïŒæé
ãªãŒãã³å ç±ïŒã§ããããã®ç©ççæ§è³ªã¯ç¬¬ïŒè¡š
ã«ç€ºãéãã§ããã å®æœäŸ ïŒ å®æœäŸïŒã«ãããŠãã¡ã¿ããŒã«500mlã«ä»£ããš
ãã¬ã³ã°ãªã³ãŒã«500mlãçšãã以åŸå®æœäŸïŒãš
åæ§ã«ããŠãšãã¬ã³ã°ãªã³ãŒã«æžæ¿æ¶²ããå ç±ä¹Ÿ
ç¥ããŠæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ç²æ«90
ïœãåŸãããã®ãã®ã¯å®å®ïŒ200âãïŒæéãªãŒ
ãã³å ç±ïŒã§ããããã®ç©ççæ§è³ªã¯ç¬¬ïŒè¡šã«ç€º
ãéãã§ããã å®æœäŸ 10 å®æœäŸïŒã«ãããŠãæ°Žé žåã«ã«ã·ãŠã ç²æ«ã
111ïœçšããã¡ã¿ããŒã«500mlã«ä»£ãã°ãªã»ãªã³
500mlãçšããåæ§ã«ããŠçé žååå¿ãããŠã°ãª
ã»ãªã³æžæ¿ç©ãšããŠçæç©ãåŸããããçŽæ¥ïŒžç·
åæåæãããšãããå šãããŒã¯ãèªãåŸãã¢ã¢
ã«ãã¢ã¹ã§ããããŸãæ¥æ¬è¬å±æ¹ã«åŸãè©Šéšã®çµ
æçé žã«ã«ã·ãŠã ã§ãããšèªããããã ãã®ãã®ã¯äžèšæžæ¿ç©ã®ãŸãŸãåã¯ãããæ¿çž®
ããŠããŒã¹ãç¶åœ¢æ ãšããŠãæ¬çºæã®åŸæŸäœåºå€
ãšããŠå©çšã§ããã å®æœäŸ 11 æ¹ææ©ãåããã¬ã©ã¹å®¹åšïŒå®¹éïŒïŒã«ããš
ãã«ã¢ã«ã³ãŒã«500mlãå ¥ããå¡©åã«ã«ã·ãŠã
ïŒCaCl2ïŒ56ïœãæ·»å ããæ¹æããŠæº¶è§£ãããåŒ
ç¶ãæ¹æããªããçé žãããªãŠã ïŒNa2CO3ã»
H2OïŒ61ïœãæ·»å ããåå¿çæç©ãæåºãããã
ãã®åå¿ã®éå¯çããå¡©åãããªãŠã ã¯ãæŽæµã«
ããæŽãå»ã€ãåŸãåžåŒéåã³å ç±ä¹Ÿç¥ã«ãã
42ïœã®ç²æ«ãåŸãã åŸãããç²æ«ã¯ïŒžç·åæåæã§ããŒã¯ã瀺ãã
ã¢ã¢ã«ãã¢ã¹ã§ããããŸãæ¥æ¬è¬å±æ¹ã®ç¢ºèªè©Šéš
æ³ã«ããè©Šéšã§çé žã«ã«ã·ãŠã ã§ããããšã確èª
ãããããã®ãã®ã¯ãªãŒãã³äž200âãïŒæéä¿
æããåŸã§ãç·åæã§å šãããŒã¯ã瀺ããå®å®
ã§ãã€ãããã®ç©ççæ§è³ªã第ïŒè¡šã«ç€ºãã å®æœäŸ 12 æ¹ææ©ãåããã¬ã©ã¹å®¹åšïŒå®¹éïŒïŒã«ããš
ãã«ã¢ã«ã³ãŒã«500mlãå ¥ããããã«ç¡é žã«ã«ã·
ãŠã ãCaNO3ïŒ2ã»4H2Oã118ïœãæ·»å ããæ¹æ
ããŠæº¶è§£ãããåŒç¶ãæ¹æããªããçé žæ°ŽçŽ ã¢ã³
ã¢ããŠã ïŒNH4HCO3ïŒ40ïœãå ããåå¿çæç©
ãæåºãããããã®åå¿ã®éå¯çããç¡é žã¢ã³ã¢
ããŠã ã¯ãæŽæµã«ããæŽãå»ã€ãåŸãåžåŒéå
ã³å ç±ä¹Ÿç¥ã«ãã39ïœã®ç²æ«ãåŸãã ãã®ç²æ«ã¯ïŒžç·åæåæã§ããŒã¯ã瀺ããã¢ã¢
ã«ãã¢ã¹ã§ããããŸãæ¥æ¬è¬å±æ¹ã®ç¢ºèªè©Šéšæ³ã«
ããè©Šéšã§çé žã«ã«ã·ãŠã ã§ããããšã確èªãã
ãããã®ãã®ã¯ãªãŒãã³äž200âãïŒæéä¿æã
ãåŸã§ãç·åæã§å šãããŒã¯ã瀺ããå®å®ã§ã
ã€ãããã®ç©ççæ§è³ªã第ïŒè¡šã«ç€ºãã å®æœäŸ 13 æ¹ææ©ãåããã¬ã©ã¹å®¹åšïŒå®¹éïŒïŒã«ããš
ãã«ã¢ã«ã³ãŒã«500mlãå ¥ããããã«æ°Žé žåã«ã«
ã·ãŠã ãCaïŒOHïŒ2ã74ïœãå ããæ¹æããªãã
çé žæ°ŽçŽ ãããªãŠã ïŒNaHCO3ïŒ84ïœãå ãã
åå¿çæç©ãæåºãããããã®åå¿ã®éå¯çãã
æ°Žé žåãããªãŠã ã¯æŽæµã«ããæŽãå»ã€ãåŸãåž
åŒéåã³å ç±ä¹Ÿç¥ã«ãã83ïœã®ç²æ«ãåŸãã ãã®ç²æ«ã¯ïŒžç·åæåæã§ããŒã¯ã瀺ããã¢ã¢
ã«ãã¢ã¹ã§ããããŸãæ¥æ¬è¬å±æ¹ã®ç¢ºèªè©Šéšæ³ã«
ããè©Šéšã§çé žã«ã«ã·ãŠã ã§ããããšã確èªãã
ãããã®ãã®ã¯ãªãŒãã³äž200âãïŒæéä¿æã
ãåŸã§ãç·åæã§å šãããŒã¯ã瀺ããå®å®ã§ã
ã€ãããã®ç©ççæ§è³ªã第ïŒè¡šã«ç€ºãã äžèšåäŸã«ãããåæã«ã«ã·ãŠã ååç©ãææ©
åªäœã®çš®é¡ã䜿çšéåã³çé žååå¿æ¹æ³ãšå ±ã«ã
åŸãããæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®ç©
æ§ãäžèšç¬¬ïŒè¡šã«ç€ºãã
ã«ãã枬å®ãããã®ã§ãããä¹çæ¹æ³ã¯æ¬æ现æž
ãéããŠåãã§ããã çæ¯éïŒãã¯ãã¡ãŒã¿ïŒæ¯éã³ãïŒãçšããŠæ¶²
äœçœ®ææ³ã«ããæ±ããã å±æçïŒã¢ããå±æèšã«ãã枬å®ããå±æçæ¢
ç¥ã®æ¶²äœã«è©Šæã浞挬ããŠæ±ããã PHïŒè©Šæ10ïœã容é100mlã®ç¡¬è³ªäžè§ãã©ã¹ã³
ã«å ¥ããæ°ãã調補ããã€ãªã³äº€æçŽæ°Ž
100mlãå ãããŽã æ ããã10ç§éæ¿ãã
ãµããŸããåŸïŒæéæŸçœ®ããå床軜ããµã
ãŸããŠå®¹é100mlã®ããŒã«ãŒã«ç§»ãããã
ã¬ã©ã¹é»æ¥µPHã¡ãŒã¿ãŒã«ãã枬å®ããã BETæ¯è¡šé¢ç©ïŒãã€ã¯ãã¡ãªãã€ãã¯ã¹ç€Ÿè£œ
N2ã¬ã¹åžçæ³ã«ããBETæ¯è¡šé¢ç©èªå枬
å®è£ 眮ã«ãã枬å®ããã 圢 ç¶ïŒæ¥ç«è£œäœæ補é»åé¡åŸ®é¡ïŒåç2000ã
20000åïŒã«ãã芳å¯ããã ãŸãæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã¯ãåžž
æž©äœæ¹¿åºŠäžå¯éæ¡ä»¶äžã«è²¯èµããå Žåé·æéïŒå°
ãªããšãïŒã±æïŒç¡å®åœ¢ç¶æ åã³äžèšç©ççæ§è³ª
ãä¿æãããã®å®å®æ§ã¯ãšã¢ãŒãªãŒãã³äžã§200
âãïŒæéå ç±ã«ãã€ãŠãå®è³ªçã«æãªãããã
400âã®å ç±ïŒãã®éã®å ç±æžéã¯ïŒïŒ 以äžã§ã
ãïŒåã¯æ°Žã®ååšã«ããçµæ¶æ§çé žã«ã«ã·ãŠã ã«
å€æ ããã æŽã«æ¬çºæçé žã«ã«ã·ãŠã ã¯ããã®ç¹æã®æ§è³ª
ãšããŠäŸãã°éŠæçã®éåžžã®æ¡ä»¶äžã«å€§æ°äžã«æ®
çºåã¯æè¯ããæ®æ£æ§ç©è³ªãåžçä¿æããããã
å ç±ãå æ°Žãªã©ã®å€çæ¡ä»¶ãå ããããšã«ããäž
èšåžçä¿æããç©è³ªããäžèšå€çæ¡ä»¶ã«å¿ããé©
床ã®æŸåºé床ã§æŸåºããæ§è³ªãå ·åãããåŸã€ãŠ
ããã¯äžèšæ®æ£æ§ç©è³ªã®åŸæŸäœåºå€ãšããŠæçšã§
ãããæ¬çºæã¯ãããåŸæŸäœããæäŸãããã®ã§
ããã 以äžæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®è£œé
æ³ã«ã€ã詳述ããã æ¬çºæçé žã«ã«ã·ãŠã ã¯ãåæã«ã«ã·ãŠã åå
ç©ãææ©åªäœç³»å ã§çé žååå¿ãããããšã«ãã
補é ããããåæãšããŠçšããããã«ã«ã·ãŠã å
åç©ã«ã¯ãé žåã«ã«ã·ãŠã ãæ°Žé žåã«ã«ã·ãŠã ã
éå±ã«ã«ã·ãŠã ãæ°ŽçŽ åã«ã«ã·ãŠã ãå¡©åã«ã«ã·
ãŠã ãèåã«ã«ã·ãŠã ããšãŠåã«ã«ã·ãŠã åã³ç¡
é žã«ã«ã·ãŠã ãå«ãŸããããŸãææ©åªäœãšããŠ
ã¯ãççŽ æ°ïŒä»¥äžã®ïŒäŸ¡ãïŒäŸ¡åã³ïŒäŸ¡ã¢ã«ã³ãŒ
ã«ã䜿çšãããïŒä»¥äžç¹ã«å¿ èŠã§ãªãéãããã
ã¢ã«ã³ãŒã«ãåã«ææ©åªäœãšããïŒä¹çã®ãã¡ã§
ç¹ã«å¥œãŸãããã®ãšããŠã¯ãã¡ãã«ã¢ã«ã³ãŒã«ã
ãšãã«ã¢ã«ã³ãŒã«ããããã«ã¢ã«ã³ãŒã«ãããã«
ã¢ã«ã³ãŒã«ããšãã¬ã³ã°ãªã³ãŒã«ãã°ãªã»ãªã³ãª
ã©ãäŸç€ºã§ãããä¹çã¯ïŒçš®åç¬ã§ãïŒçš®ä»¥äžæ··
åããŠã䜿çšããããšãã§ãããäžèšææ©åªäœã¯
ãŸãïŒå®¹éïŒ æªæºã®æ°Žãå«ãã§ããŠãããããã®
æ§ãªå«æ°Žã¢ã«ã³ãŒã«ãçšããå Žåãåæ§ã«æ¬çºæ
ææã®ã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ãååŸã§ã
ãã æ¬çºæã®çé žååå¿ã¯ãäºé žåççŽ åã¯çé žå¡©
ååç©ãçšããŠå®æœããããçšããããäºé žåç
çŽ ã¯æ°äœã§ããå¿ èŠã¯ãªããåºäœïŒãã©ã€ã¢ã€
ã¹ïŒã§ãã€ãŠããããäžè¬ã«ã¯äŸãã°ç³ç°ç³çŒæ
æã«çºçããå»ã¬ã¹ããåŸãããæ¿åºŠ30容éïŒ å
åŸã®äºé žåççŽ ã¬ã¹ã䜿çšã§ããããŸãçé žå¡©å
åç©ãšããŠã¯ãäŸãã°çé žãããªãŠã ãçé žæ°ŽçŽ
ãããªãŠã ãçé žã«ãªãŠã ãçé žã¢ã³ã¢ããŠã ã
çé žæ°ŽçŽ ã¢ã³ã¢ããŠã çãäŸç€ºã§ãããäžèšçé ž
ååå¿ã¯éåžžåæã«ã«ã·ãŠã ååç©ãææ©åªäœã«
溶解ä¹è³æžæ¿ããã液äžã«ãäºé žåççŽ ãå¹ã蟌
ããåã¯çé žå¡©ååç©ãæ¹æäžã«æ·»å åã¯æ·»å åŸ
æ¹ææ··åããããšã«ããè¡ãªããããäºé žåççŽ
ã®å¹ã蟌ã¿ã«ããå Žåããã®ã¬ã¹æ¹æã®ã¿ã§åå¿
ç³»å ãå ååäžãšãªãå Žåãããããéåžžæ©æ¢°ç
æ¹ææäœãæ¡çšããã®ã奜ãŸãããçé žååå¿ã®
枩床ã¯ãçšããææ©åªäœã®æ²žç¹ä»¥äžã§ããã°ç¹ã«
å¶éãããªãããéåžžçŽ45â以äžã奜ãŸããã¯ïŒ
ã45âã®ç¯å²å ãšããããåæã«ã«ã·ãŠã åå
ç©ãææ©åªäœåã³çé žåå€ã®äœ¿çšå²åã¯ãé©å®ã«
決å®ããããšãã§ãããéåžžææ©åªäœïŒåœãå
æã«ã«ã·ãŠã ååç©ãçŽïŒã¢ã«ä»¥äžãäžè¬ã«çŽ
0.05ãïŒã¢ã«ã®ç¯å²ã§çšããçé žåå€ã¯åæã«å¯Ÿ
ãå°ãªããšãçè«åœéãšãªãéã§çšããã®ãæãŸ
ããã ãŸãæ¬çºæã®äžèšçé žååå¿ã¯ãåå¿ç³»å ã«ç¡
é žã¢ã³ã¢ããŠã ãé ¢é žã¢ã³ã¢ããŠã ãå¡©åã¢ã³ã¢
ããŠã çãååšãããããšã«ãããåå¿ãä¿é²ã§
ããå Žåããããä¹çåå¿ä¿é²å€ãšããŠçšããã
ãè©Šè¬ã¯ãéåžžåæã«ã«ã·ãŠã ååç©ã®çŽ0.05ã
20ééïŒ ãšãªãéã§åå¿ç³»å ã«ååšãããããšã
ã§ããã äžèšçé žååå¿ã®çµç¹ã¯ãçé žåå€ãšããŠäºé ž
åççŽ ãçšããå Žåãçé žååå¿ç³»ã®ãµã³ããªã³
ã°æ¶²ãæ°Žã«æžæ¿ãããŠããã®PHãæ±ããããšã«ã
ã決å®ããããéåžžäžèšæžæ¿æ¶²ïŒ10ïœïŒ100mlæ°Ž
ãšããŠïŒã®PHãã»ãŒïŒãïŒãšãªãç¹ãçµç¹ãšãã
ãããŸãçé žåå€ãšããŠçé žå¡©ååç©ãçšããå Ž
åãäžèšåå¿çµç¹ã¯ãç³»å ã«åå¿çæç©ããã¯ã
æåºããªããªãæç¹ãšããã®ããããããããŠæ¬
çºæã®ã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ãå«æããæ
æ©åªäœæžæ¿æ¶²ãååŸã§ããã æ¬çºæã®ã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã¯ãäžèš
æžæ¿æ¶²ã®ãŸãŸåã¯ãããé©åœã«ããŒã¹ãåããŠã
ãŒã¹ã圢æ ã§ææçšéã«å©çšããããšãã§ãã
ããéåžžçé žã«ã«ã·ãŠã ã®åªäœæžæ¿æ¶²ãéããŠ
ææ©åªäœãé€å»ãããããåžžæ³ã«åŸãå ç±ä¹Ÿç¥ã
ç²ç ãããæã¯äžèšæžæ¿æ¶²ãçŽæ¥ä¹Ÿç¥ããããšã«
ãããç²æ«è£œåãšããŠåé¢ååŸããããå°çé žå
ã®æ¡ä»¶ã«ãã€ãŠã¯ãç®çãšããã¢ã¢ã«ãã¢ã¹çé ž
ã«ã«ã·ãŠã ã®ä»ã«å¯çç©ãçæããå¯èœæ§ããã
ãããã®å¯çç©ã¯å¿ èŠã«å¿ããŠéåžžã®æŽæµæäœã
æœãããšã«ããé€å»ã§ããã æ¬çºæã¯äžèšã®åŠãããŠåŸãããæžæ¿æ¶²åœ¢æ ä¹
è³ããŒã¹ã圢æ åã³ç²æ«åœ¢æ ã®ã¢ã¢ã«ãã¢ã¹çé ž
ã«ã«ã·ãŠã åã³ä¹çãåºå€ãšããŠå«æããé€æŸäœ
ãæäŸãããã®ã§ãããæ¬çºææ¹æ³ã«ããåŸãã
ãã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ãåºå€ãšããåŸæŸ
äœïŒä»¥äžåã«æ¬çºæåŸæŸäœãšããïŒã¯ãéåžžã®æ¡
件äžã«å€§æ°äžã«æ®çºä¹è³æè¯ããç©è³ªæã¯æ°Žåå
ã¯ç±ãä»ããŠåŸæŸäœå€éšã«æ¡æ£ããç©è³ªã§ããã
éåžžã®éŠæãææã蟲è¬ãå»è¬ãåå³ç©è³ªãé²é»Ž
å€çãå å«ããããä¹çç©è³ªïŒä»¥äžãäœçšç©è³ªã
ãšåŒã¶ïŒã®å ·äœäŸãšããŠã¯ãäžèšåååç©ãäŸç€º
ã§ããã (1) éŠæ ã¢ã»ãé ¢é žãšãã«ãã¢ãããŒã«ãã¢ãã«ã·ã³ã
ããã¯ã¢ã«ããããã€ãœåèé žãšãã«ããŠã³ãã«
ã©ã¯ãã³ããããªã³ããšãã¬ã³ãã©ã·ã¬ãŒãããª
ã€ã²ããŒã«ãã«ããªã«é žãšãã«ãã«ããã³é žã¢ãª
ã«ãã«ããã³é žãšãã«ãïœâã«ã«ãã³ãã¯ãã³ã¢
ã«ããããã±ã€ç®ã¢ã«ã³ãŒã«ãã²ã©ããªãŒã«ãé ¢
é žãžã¡ãã«ãã³ãžã«ã«ã«ããã«ãã·ãã©ãŒã«ãã·
ãããããŒã«ããžããããžã€ã¹ã¢ã³ããžã¡ãã«ã
ã³ãžã«ã«ã«ãããŒã«ãããã©ããããªãããŒã«ã
ãã«ãããªãŒã«ãβâãããã«ãšãã«ãšãŒãã«ã
ããã©ã¯ãã³ãããããã·ã·ãããã©ãŒã«ãβâ
ããšãã«ãšãã«ã¢ã«ã³ãŒã«ãããšãã«é ¢é žãšã
ã«ããã³ãžã«ã¢ã«ã³ãŒã«ããã«ããŒã«ãã ã¹ã¯ã
ïœâã¡ãã«ã¢ã³ã¹ã©ãã«é žã¡ãã«ãã¡ã³ããŒã«ã
ãšãã³ããªãããŒã«ããªã¢ãã³ç (2) ææ ã¡ãã¬ã³ãã«ãŒãã¡ãã«ãã€ãªã¬ããããµã«ã
ã¢ãŒãã©ãã¯ãã€ã³ãžãŽãã³ã³ãŽãŒã¬ãããã³ã
ãã³ãã©ãŠã³ããã¯ã»ãªã³ããªã¬ã³ãžããã°ã
ã·ã³ãããŒããã³ç (3) èŸ²è¬ ãžã¡ãã«ãã¿ã¬ãŒããïŒâãšãã«âïŒïŒïŒâã
ããµã³ãžãªãŒã«ãã€ã³ããã³ããžã¡ãã«ã«ãŒãã¡
ã€ããã€ã«ã¬ããªã³ãPCPå€ïŒãã³ã¿ã¯ãã«ã
ãšããŒã«ïŒãMEPå€ïŒãžã¡ãã«ããªãã¹ããšãŒ
ãïŒãECPå€ïŒãžãšãã«ãžã¯ãã«ããšãã«ããªã
ã¹ããšãŒãïŒãã¯ãããã¯ãªã³ããããè³ããã
ã¿ãªã³ããã©ãžã¯ãã«ãã³ãŒã³ãã¡ã¿ã¢ã«ããã (4) å»è¬ ãã¿ãã³ïŒ¡ããã¿ãã³ïŒ€ããã¿ãã³ïŒ¥ããã¿ã
ã³ïŒ«ãããšããŒã«ã¹ã«ãã³é žãããšãã«ãã³ããŒ
ã«ãåèé žãžãã«ã³ã«ããã³ãããã«é žãã«ã¡ã¿
ãŸã³ããšããµã©ãããã·ã¯ãããã¯ã¹ãªã©ãã³ã
ã·ãã«ãã³ (5) åå³ç©è³ª ã¯ãšã³é žãä¹³é žããªã³ãŽé žããµãã«ãªã³ãã¹ã
ããªãµã€ãããœã«ãããŒã«ããã«ã·ã³ããããŒ
ããã«ããšã€ã³ (6) é²ã°ãå€ ãµãªãã«ã¢ããªããïŒâ2â²âãžãªãã·âïŒïŒ
5â²âãžã¯ãããžããšãã«ã¡ã¿ã³ããªã«ãããšã
ã«ãããšããŒã«ããžããšãã«ããã¢ãã³ããŸãŒã« (7) ãã®ä» æ°åæ§é²éå€ïŒäºç¡é žããªã¡ãã«ã¹ã«ãããŠ
ã ãäºç¡é žãžã€ãœãããã«ã¢ã³ã¢ããŠã ã
ïŒïŒïŒïŒïŒãã³ãŸããªã¢ãŸãŒã« 殺èå€ïŒã€ãœããããªã©ã³å€ãã«ã«ãã³ããŸãŒ
ã«å€ æ€ç©çé·èª¿æŽå€ïŒããŒãšå€ãïŒâïŒïŒ®âãã³ãž
ã«ïŒã¢ããããªã³ããã·ãã¬ãªã³ããªã©ã
ã³å€ãïŒïŒ®ïŒïŒ®âããªã¡ãã«âïŒâã¡ã
ã«âïŒâïŒïŒïŒïŒïŒïŒâããªã¡ãã«âïŒâ
ã·ã¯ãããã»ã³âïŒâã€ã«ïŒâïŒâããã
ãã«ã¢ã³ã¢ããŠã é£åä¿åæïŒããããé ¢é žãããªãŠã ãããã
ãªã³é žãããªãŠã ãã©ãŠãªã«ããªã¡ãã«ã¢
ã³ã¢ããŠã âïŒïŒïŒïŒïŒâããªã¯ãã«ããš
ãããµã€ã é žåé²æ¢å€ïŒïŒïŒ4â²âããªãã¹âïŒïŒâã¡ãã«
âïŒâïœããã«ããšããŒã«ïŒããžã©ãŠãªã«
ããªãžããããªããŒãããã³ã¿ãšãªã¹ãªã
ã«âããã©ãã¹ãïŒâïŒïŒïŒïŒâãžãŒã¿ãŒ
ã·ã€ãªããã«âïŒâããããã·ããšããŒ
ã«ïŒããããªããŒã 玫å€ç·åžåå€ïŒïŒïŒïŒâãžããããã·ãã³ãŸã
ãšãã³ãããšãã«ãµãªã·ã¬ãŒããïŒâ
ïŒ2â²âããããã·â5â²âã¡ã«ããšãã«ïŒâ
ãã³ãŸããªã¢ãŸãŒã« ããºãå¿é¿å€ïŒÎ²âãïŒâïŒïŒïŒïŒâãžã¡ãã«
âïŒâOXOã»ã·ã¯ãããã·ã«ïŒâïŒâã
ãããã·ãšãã«ãã°ã«ã¿ãªãã 液äœçºæ³¡å€ïŒãã©ã»ãã«ãšã³ã»ã¹ã«ããã«ã¢ãž
ã äžèšåçš®äœçšç©è³ªãåžçä¿æããæ¬çºæåŸæŸäœ
ã¯ãæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®è£œé ãš
åæã«åã¯äºã該çé žã«ã«ã·ãŠã ã補é åŸããã«
äœçšç©è³ªãåžçãããããšã«ãã補é ããããšã
ã§ããããã®æ¹æ³ã®ä»£è¡šäŸãšããŠã¯ä»¥äžã®ãã®ã
äŸç€ºã§ããã (1) æ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®è£œé
æãçšããææ©åªäœäžã«ææã®äœçšç©è³ªãæ·»å
ååšãããäžè¿°ããçé žååå¿ãè¡ãªãã (2) åèšããçé žååå¿ã«ããåŸãããã¢ã¢ã«ã
ã¢ã¹çé žã«ã«ã·ãŠã ãå«æããææ©åªäœæžæ¿æ¶²
äžã«ãææã®äœçšç©è³ªãæ·»å ããã (3) æ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®ç²æ«è£œ
åã«ãäºãé©åœãªæº¶åªã«æº¶è§£ãããäœçšç©è³ªã®
液ãåŽé§ããããæã¯é©åœãªæº¶åªäžã«äžèšç²æ«
補åãšäœçšç©è³ªãšã浞挬ãã次ãã§æº¶åªãé€å»
ïŒä¹Ÿç¥ïŒããã äžèšãããã®æ¹æ³ãæ¡çšããå Žåããäœçšç©è³ª
ã®äœ¿çšéã¯ã該äœçšç©è³ªã®çš®é¡ãåŸãããåŸæŸäœ
ã«èŠæãããçšéä¹è³è©²åŸæŸäœããã®äœçšç©è³ªã®
æ®æ£é床ïŒæç¶æéïŒçã«å¿ããŠé©å®ã«æ±ºå®ã
ããæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®é£œååž
çéãäžéãšããŠéåžžçšããäœçšç©è³ªã¯ã»ãŒå®å š
ã«åžçä¿æããããäžè¬ã«ãã®åžçä¿æéã¯ãã¢
ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ééãåºæºãšããŠ
0.001ã2.0åééçšåºŠãšããã®ã奜ãŸããããŸã
äžèš(3)ã«ç€ºãæ¹æ³ã«ãããŠçšãã溶åªãšããŠã¯ã
äŸãã°ã¡ã¿ããŒã«ããšã¿ããŒã«ãã¢ã»ãã³ãé ¢é ž
ãšãã«ãããã«ã»ã«ãœã«ãããã«ãšã³ããããµ
ã³ãåå¡©åççŽ ãã¯ãããã«ã çãäŸç€ºã§ããã
也ç¥æ段ãšããŠã¯å溶åªã®æ²žç¹åã¯ãã以äžã®æž©
床ã«å ç±ããããæžå§äžã«ç±é¢šä¹Ÿç¥ãããã也ç¥
空æ°ã«ããé颚也ç¥ããçã®æ段ãæ¡çšããããš
ãã§ããã ããããŠåŸãããæ¬çºæåŸæŸäœã¯ãé·æã«äºã€
ãŠäœçšç©è³ªã®å€è³ªãå£åçãé²æ¢ã§ãããã®ã§ã
ããäžã€è©²äœçšç©è³ªãé©åœãªæŸåºé床ããã€ãŠå®¹
æã«æŸåºãäŸçµŠã§ãããã®ã§ãããäœçšç©è³ªæ¬æ¥
ã®äœçšãé·æã«äºã€ãŠæå¹ã«æç¶çºçŸãåŸããã®
ã§ããã 以äžå®æœäŸåã³æ¯èŒäŸãæããæ¬çºæãæŽã«è©³
è¿°ããã å®æœäŸ ïŒ æ¹ææ©åã³ã¬ã¹å°å ¥ç®¡ãåããã¬ã©ã¹å®¹åšïŒå®¹
éïŒïŒã«ãæ°Žé žåã«ã«ã·ãŠã ç²æ«300ïœåã³ã¡
ã¿ããŒã«ïŒãå ãã18âïŒåžžæž©ïŒã§ã30容éïŒ
ã®äºé žåççŽ ã¬ã¹ãå§å ¥ããçé žååå¿ãè¡ãªã€
ãã çé žååå¿éäžã«ãããŠéæãµã³ããªã³ã°ãè¡
ãªããæ¡åãµã³ããªã³ã°ãæ°Žã«æžæ¿ããã10ïŒ æž
æ¿æ¶²ã®PHãïŒã«ãªã€ãæç¹ã§åå¿ïŒæé«æž©åºŠ27
âïŒãçµäºããã åŸãããçæç©ãåžåŒéããŠã¡ã¿ããŒã«é€å»
ãã次ã«ç©ºæ°åŸªç°åŒå ç±ä¹Ÿç¥æ©ã«ãã110âã§ïŒ
æé也ç¥ãã也ç¥ç©ãç²ç ããŠæ¬çºæã¢ã¢ã«ãã¢
ã¹çé žã«ã«ã·ãŠã ç²æ«380ïœãåŸãã ãã®ç²æ«ã®ïŒžç·åæåæå³ïŒCuKaãNiãã€ã«
ã¿ãŒïŒã¯ç¬¬ïŒå³ã«ç€ºãéãã§ãããå šãããŒã¯ã¯
èªãããããã¢ã¢ã«ãã¢ã¹ã§ããããšãå€ãããŸ
ããã®ç²æ«ã¯æ¥æ¬è¬å±æ¹ã®çé žã«ã«ã·ãŠã 確èªè©Š
éšæ¹æ³ã«åŸãè©Šéšããçµæçé žã«ã«ã·ãŠã ã§ãã
ãšç¢ºèªãããããã®ç©ççæ§è³ªã第ïŒè¡šã«ç€ºãã
æŽã«ãã®ç²æ«ããªãŒãã³äž200âã§ïŒæéä¿æåŸ
åæ§ã«ïŒžç·åæåæãè¡ãªã€ãçµæã¯ç¬¬ïŒå³ã«ç€º
ãéãã§ãããå šãããŒã¯ã¯èªããããå®å®ã§ã
ã€ããå°ãªãŒãã³äžã§400âã§ïŒæéçŒæåŸã®ïŒž
ç·åæå³ã¯ç¬¬ïŒå³ã«ç€ºãéãã§ãããã«ã«ãµã€ã
ã«å€åããŠããããšã確èªãããã ãŸãäžèšã§åŸãã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ç²
æ«ã®ç€ºå·®ç±ã»ç±å€©ç§€æž¬å®å³ã第ïŒå³ã«ç€ºãã該å³
ãã400âãŸã§ã®å ç±æžéã¯1.0ïŒ ä»¥äžã§ããããš
ãå€ããå°è©²å³ã«ããã枬å®æ¡ä»¶ã¯æ¬¡ã®éãã§ã
ããå³äžïŒã¯ç€ºå·®ç±æ²ç·ïŒDTAïŒãã(2)ã¯å ç±
æžéæ²ç·ïŒTGïŒãããŸã(3)ã¯æž©åºŠæ²ç·ïŒâïŒã
瀺ãã è©Šææ¡åéïŒ11mg ææž©é床ïŒ10âïŒå 瀺差ç±æ床ïŒÂ±100ÎŒV æšæºè©ŠæïŒÎ±âAl2O3 å®æœäŸ ïŒ æ¹ææ©åã³ã¬ã¹å°å ¥ç®¡ãåããã¬ã©ã¹å®¹åšïŒå®¹
éïŒïŒã«ãé žåã«ã«ã·ãŠã ç²æ«ïŒ200ã¡ãã·ãŠ
ãã¹åïŒ28ïœåã³ã¡ã¿ããŒã«500mlãå ããæ¹æ
ããªãã25âïŒåžžæž©ïŒã§ãäºã空æ°ã«ããæ¿åºŠã
30容éïŒ ã«èª¿è£œããäºé žåççŽ ã¬ã¹ãéããçé ž
ååå¿ïŒæé«æž©åºŠ32âïŒãè¡ãªããå®æœäŸïŒãšå
æ§ã®æ¹æ³ã«ããåå¿çµäºæç¹ãå€å®ããã ããããŠåŸãããçæç©ããåžåŒéã«ããã¡
ã¿ããŒã«ãé€å»ããæ®æž£ã也ç¥åšã«ãŠ110âã§ïŒ
æé也ç¥ããç²ç ããŠæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«
ã«ã·ãŠã ç²æ«45ïœãåŸãã åŸãããç²æ«ã¯ãç·åæåæã®çµæ第ïŒå³ãš
åæ§ã«å šãããŒã¯ãèªãããããæ¥æ¬è¬å±æ¹ã®ç
é žã«ã«ã·ãŠã 確èªè©Šéšæ¹æ³ã«ããçé žã«ã«ã·ãŠã
ã§ãããšèªããããããŸããªãŒãã³äž200âã§ïŒ
æéä¿æåŸãç·åæåæã§å šãããŒã¯ãèªãã
ããå®å®ã§ãã€ãããã®ãã®ã®ç©ççæ§è³ªã¯ç¬¬ïŒ
è¡šã«ç€ºãéãã§ããã æ¯èŒäŸ ïŒ å®æœäŸïŒãšåäžã®åå¿å®¹åšã«ã40ééïŒ æ¿åºŠã®
æ°Žé žåã«ã«ã·ãŠã æ°Žæžæ¿ç©ïŒç³ç°ä¹³ã¹ã©ãªãŒïŒ
250ïœåã³ã¡ã¿ããŒã«ïŒãå ãïŒãã®ç³»ã®æ°Žé ž
åã«ã«ã·ãŠã ã®ã¡ã¿ããŒã«ã«å¯Ÿããæ¿åºŠã¯ïŒã¢
ã«ïŒã¡ã¿ããŒã«ã§ãããã¡ã¿ããŒã«ã«å¯Ÿããæ°Ž
åéã¯10容éïŒ ã§ããïŒãããã«30容éïŒ ã®äºé ž
åççŽ ã¬ã¹ãéããŠçé žååå¿ãè¡ãªããå®æœäŸ
ïŒãšåäžæ¹æ³ã«ããçé žååå¿çµäºç¹ãå€å®ãã
åŸãããçæç©ãåžåŒéãããšãããæ®ãã©ã
ã¹ãŠãçŽãééãããééããçæç©ïŒã¡ã¿ã
ãŒã«æžæ¿ç©ïŒã«ã€ããã¡ã¿ããŒã«ãæ®çºãããŠåŸ
ãç²æ«ã¯ãç·åæåæã®çµæçµæ¶è³ªïŒããã©ã€
ãåïŒçé žã«ã«ã·ãŠã ã§ãããšç¢ºèªãããããã®
ãã®ã®ç©ççæ§è³ªã第ïŒè¡šã«ç€ºãã å®æœäŸ ïŒ æ¹ææ©åã³ã¬ã¹å°å ¥ç®¡ãåããã¬ã©ã¹å®¹åšïŒå®¹
éïŒïŒã«ãæ°Žé žåã«ã«ã·ãŠã ç²æ«74ïœåã³ã¡ã¿
ããŒã«500mlãå ããæ¹æããªãã30容éïŒ ã®äº
é žåççŽ ã¬ã¹ãïŒïŒåã®é床ã§éããŠçé žåå
å¿ãè¡ãªããå®æœäŸïŒãšåäžæ¹æ³ã«ããå€å®ãã
çé žååå¿çµäºæç¹ïŒçŽ1.5æéåŸïŒã§åŸããã
çæç©ã®ã¡ã¿ããŒã«æžæ¿ç©ãåžåŒéããŠã¡ã¿ã
ãŒã«ãåé¢ããæ®æž£ã也ç¥æ©ã«ãŠ110âã§ïŒæé
也ç¥ããŠ91ïœã®ç²æ«ãåŸãã ãã®ç²æ«ã¯ïŒžç·åæåæã®çµæ第ïŒå³ãšåæ§ã«
å šãããŒã¯ã瀺ããã¢ã¢ã«ãã¢ã¹ã§ããããŸãæ¥
æ¬è¬å±æ¹ã«ããè©Šéšã®çµæçé žã«ã«ã·ãŠã ã§ãã
ãšç¢ºèªãããããŸãããã¯ãªãŒãã³äž200âãïŒ
æéä¿æåŸãç·åæåæã§å šãããŒã¯ã瀺ãã
å®å®ã§ãã€ãããã®ãã®ã®ç©ççæ§è³ªã第ïŒè¡šã«
瀺ãã å®æœäŸ ïŒ å®æœäŸïŒã«ãããŠãã¡ã¿ããŒã«500mlããã¡ã¿
ããŒã«490mlåã³æ°Ž10mlïŒã¡ã¿ããŒã«ã«å¯ŸãïŒå®¹
éïŒ ïŒã«ä»£ããåæ§ã«ããŠçé žååå¿ãè¡ãªãã
æ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ç²æ«84ïœãåŸ
ãããã®ãã®ã¯å®å®ïŒ200âãïŒæéãªãŒãã³å
ç±ïŒã§ããããã®ç©ççæ§è³ªã¯ç¬¬ïŒè¡šã«ç€ºãéã
ã§ããã æ¯èŒäŸ ïŒ å®æœäŸïŒã«ãããŠãã¡ã¿ããŒã«500mlãã¡ã¿ã
ãŒã«450mlåã³æ°Ž50mlïŒã¡ã¿ããŒã«ã«å¯Ÿã10容é
ïŒ ïŒã«ä»£ããåæ§ã«çé žååå¿ãè¡ãªããåæ§ã«
åå¿çµäºæç¹ãæ±ããã該åå¿çµäºæç¹ã«ããã
çæç©ã¯åžåŒéã®éçŽãééãå¥äžå¯èœã§
ãã€ãããã液ãå ç±ä¹Ÿç¥ããŠã¡ã¿ããŒã«ãæ®
çºããããã也ç¥éäžã§æ¢ã«çµæ¶è³ªïŒããã©ã€ã
åïŒçé žã«ã«ã·ãŠã ã«ãªã€ãŠããããšãç·åæ
åæã§ç¢ºèªãããããã®ãã®ã®ç©ççæ§è³ªã第ïŒ
è¡šã«ç€ºãã å®æœäŸ ïŒ æ¹ææ©ããã³ã¬ã¹å°å ¥ç®¡ãåããã¬ã©ã¹å®¹åš
ïŒå®¹é500mlïŒã«éå±ã«ã«ã·ãŠã 110ïœããã³ã¡ã¿
ããŒã«250mlãå ããæ¹æããªãã25âïŒåžžæž©ïŒ
ã§ãäºã空æ°ã«ããæ¿åºŠã30容éïŒ ã«èª¿æŽããäº
é žåççŽ ã¬ã¹ãéããçé žååå¿ãè¡ãªãå®æœäŸ
ïŒãšåæ§ã®æ¹æ³ã«ããåå¿çµäºæç¹ãå€å®ããã ããããŠåŸãããçæç©ããåžåŒéã«ããã¡
ã¿ããŒã«ãé€å»ããæ®æž£ã也ç¥åšã«ãŠ110âã§ïŒ
æé也ç¥ããŠãæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠ
ã ç²æ«20ïœãåŸãã åŸãããç²æ«ã¯ãç·åæåæã®çµæ第ïŒå³ãš
åæ§ã«å šãããŒã¯ãèªãããããæ¥æ¬è¬å±æ¹ã®ç
é žã«ã«ã·ãŠã 確èªè©Šéšæ¹æ³ã«ããçé žã«ã«ã·ãŠã
ã§ãããšèªããããããŸããªãŒãã³äž200âã§ïŒ
æéä¿æåŸãç·åæåæã§å šãããŒã¯ãèªãã
ããå®å®ã§ãã€ãããã®ãã®ã®ç©ççæ§è³ªã¯ç¬¬ïŒ
è¡šã«ç€ºãéãã§ããã å®æœäŸ ïŒ å®æœäŸïŒã«ãããŠã¡ã¿ããŒã«500mlããïœâã
ããã«ã¢ã«ã³ãŒã«500mlã«ä»£ããåæ§ã«ããŠçé ž
ååå¿ãè¡ãªããå®æœäŸïŒãšåæ§ã«ããŠåå¿çµäº
æç¹ãæ±ãããšããçŽïŒæéãèŠãããåŸããã
çæç©ãå®æœäŸïŒãšåæ§ã«ããŠåŠçããŠæ¬çºæã¢
ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ç²æ«90ïœãåŸãããã®
ãã®ã®ç©ççæ§è³ªã第ïŒè¡šã«ç€ºãã å®æœäŸ ïŒ å®æœäŸïŒã«ãããŠã¡ã¿ããŒã«500mlãïœâãã
ãã«ã¢ã«ã³ãŒã«500mlãšãããŸãçé žååå¿ç³»å
ã«åå¿ä¿é²å€ãšããŠå¡©åã¢ã³ã¢ããŠã 0.4ïœãæ·»
å ããåæ§ã«ããŠçé žååå¿ãè¡ãªããåå¿çµäº
æç¹ãå€å®ãããšãããçŽ1.5æéãèŠãããåŸ
ãããçæç©ãåæ§ã«åŠçããŠåŸãããã¢ã¢ã«ã
ã¢ã¹çé žã«ã«ã·ãŠã ç²æ«ïŒåé91ïœïŒã®ç©ççæ§
質ã第ïŒè¡šã«ç€ºãã å®æœäŸ ïŒ å®æœäŸïŒã«ãããŠãã¡ã¿ããŒã«500mlã«ä»£ãïœ
âããã«ã¢ã«ã³ãŒã«500mlãçšããåæ§ã«çé žå
åå¿ãããåå¿çµäºç¹ãæ±ãããã®æç¹ã«ããã
çæç©ïŒïœâããã«ã¢ã«ã³ãŒã«æžæ¿ç©ïŒãå ç±ä¹Ÿ
ç¥ããŠãæ¬çºæã®ã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ç²
æ«82ïœãåŸãããã®ãã®ã¯å®å®ïŒ200âãïŒæé
ãªãŒãã³å ç±ïŒã§ããããã®ç©ççæ§è³ªã¯ç¬¬ïŒè¡š
ã«ç€ºãéãã§ããã å®æœäŸ ïŒ å®æœäŸïŒã«ãããŠãã¡ã¿ããŒã«500mlã«ä»£ããš
ãã¬ã³ã°ãªã³ãŒã«500mlãçšãã以åŸå®æœäŸïŒãš
åæ§ã«ããŠãšãã¬ã³ã°ãªã³ãŒã«æžæ¿æ¶²ããå ç±ä¹Ÿ
ç¥ããŠæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ç²æ«90
ïœãåŸãããã®ãã®ã¯å®å®ïŒ200âãïŒæéãªãŒ
ãã³å ç±ïŒã§ããããã®ç©ççæ§è³ªã¯ç¬¬ïŒè¡šã«ç€º
ãéãã§ããã å®æœäŸ 10 å®æœäŸïŒã«ãããŠãæ°Žé žåã«ã«ã·ãŠã ç²æ«ã
111ïœçšããã¡ã¿ããŒã«500mlã«ä»£ãã°ãªã»ãªã³
500mlãçšããåæ§ã«ããŠçé žååå¿ãããŠã°ãª
ã»ãªã³æžæ¿ç©ãšããŠçæç©ãåŸããããçŽæ¥ïŒžç·
åæåæãããšãããå šãããŒã¯ãèªãåŸãã¢ã¢
ã«ãã¢ã¹ã§ããããŸãæ¥æ¬è¬å±æ¹ã«åŸãè©Šéšã®çµ
æçé žã«ã«ã·ãŠã ã§ãããšèªããããã ãã®ãã®ã¯äžèšæžæ¿ç©ã®ãŸãŸãåã¯ãããæ¿çž®
ããŠããŒã¹ãç¶åœ¢æ ãšããŠãæ¬çºæã®åŸæŸäœåºå€
ãšããŠå©çšã§ããã å®æœäŸ 11 æ¹ææ©ãåããã¬ã©ã¹å®¹åšïŒå®¹éïŒïŒã«ããš
ãã«ã¢ã«ã³ãŒã«500mlãå ¥ããå¡©åã«ã«ã·ãŠã
ïŒCaCl2ïŒ56ïœãæ·»å ããæ¹æããŠæº¶è§£ãããåŒ
ç¶ãæ¹æããªããçé žãããªãŠã ïŒNa2CO3ã»
H2OïŒ61ïœãæ·»å ããåå¿çæç©ãæåºãããã
ãã®åå¿ã®éå¯çããå¡©åãããªãŠã ã¯ãæŽæµã«
ããæŽãå»ã€ãåŸãåžåŒéåã³å ç±ä¹Ÿç¥ã«ãã
42ïœã®ç²æ«ãåŸãã åŸãããç²æ«ã¯ïŒžç·åæåæã§ããŒã¯ã瀺ãã
ã¢ã¢ã«ãã¢ã¹ã§ããããŸãæ¥æ¬è¬å±æ¹ã®ç¢ºèªè©Šéš
æ³ã«ããè©Šéšã§çé žã«ã«ã·ãŠã ã§ããããšã確èª
ãããããã®ãã®ã¯ãªãŒãã³äž200âãïŒæéä¿
æããåŸã§ãç·åæã§å šãããŒã¯ã瀺ããå®å®
ã§ãã€ãããã®ç©ççæ§è³ªã第ïŒè¡šã«ç€ºãã å®æœäŸ 12 æ¹ææ©ãåããã¬ã©ã¹å®¹åšïŒå®¹éïŒïŒã«ããš
ãã«ã¢ã«ã³ãŒã«500mlãå ¥ããããã«ç¡é žã«ã«ã·
ãŠã ãCaNO3ïŒ2ã»4H2Oã118ïœãæ·»å ããæ¹æ
ããŠæº¶è§£ãããåŒç¶ãæ¹æããªããçé žæ°ŽçŽ ã¢ã³
ã¢ããŠã ïŒNH4HCO3ïŒ40ïœãå ããåå¿çæç©
ãæåºãããããã®åå¿ã®éå¯çããç¡é žã¢ã³ã¢
ããŠã ã¯ãæŽæµã«ããæŽãå»ã€ãåŸãåžåŒéå
ã³å ç±ä¹Ÿç¥ã«ãã39ïœã®ç²æ«ãåŸãã ãã®ç²æ«ã¯ïŒžç·åæåæã§ããŒã¯ã瀺ããã¢ã¢
ã«ãã¢ã¹ã§ããããŸãæ¥æ¬è¬å±æ¹ã®ç¢ºèªè©Šéšæ³ã«
ããè©Šéšã§çé žã«ã«ã·ãŠã ã§ããããšã確èªãã
ãããã®ãã®ã¯ãªãŒãã³äž200âãïŒæéä¿æã
ãåŸã§ãç·åæã§å šãããŒã¯ã瀺ããå®å®ã§ã
ã€ãããã®ç©ççæ§è³ªã第ïŒè¡šã«ç€ºãã å®æœäŸ 13 æ¹ææ©ãåããã¬ã©ã¹å®¹åšïŒå®¹éïŒïŒã«ããš
ãã«ã¢ã«ã³ãŒã«500mlãå ¥ããããã«æ°Žé žåã«ã«
ã·ãŠã ãCaïŒOHïŒ2ã74ïœãå ããæ¹æããªãã
çé žæ°ŽçŽ ãããªãŠã ïŒNaHCO3ïŒ84ïœãå ãã
åå¿çæç©ãæåºãããããã®åå¿ã®éå¯çãã
æ°Žé žåãããªãŠã ã¯æŽæµã«ããæŽãå»ã€ãåŸãåž
åŒéåã³å ç±ä¹Ÿç¥ã«ãã83ïœã®ç²æ«ãåŸãã ãã®ç²æ«ã¯ïŒžç·åæåæã§ããŒã¯ã瀺ããã¢ã¢
ã«ãã¢ã¹ã§ããããŸãæ¥æ¬è¬å±æ¹ã®ç¢ºèªè©Šéšæ³ã«
ããè©Šéšã§çé žã«ã«ã·ãŠã ã§ããããšã確èªãã
ãããã®ãã®ã¯ãªãŒãã³äž200âãïŒæéä¿æã
ãåŸã§ãç·åæã§å šãããŒã¯ã瀺ããå®å®ã§ã
ã€ãããã®ç©ççæ§è³ªã第ïŒè¡šã«ç€ºãã äžèšåäŸã«ãããåæã«ã«ã·ãŠã ååç©ãææ©
åªäœã®çš®é¡ã䜿çšéåã³çé žååå¿æ¹æ³ãšå ±ã«ã
åŸãããæ¬çºæã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®ç©
æ§ãäžèšç¬¬ïŒè¡šã«ç€ºãã
ãè¡šã
å®æœäŸ 14
å®æœäŸïŒã«ãããŠæ°Žé
žåã«ã«ã·ãŠã ç²æ«300ïœã
ã¡ã³ããŒã«ïŒïœåã³ã¡ã¿ããŒã«ïŒãçšãçé žå
åå¿ãè¡ãªãçŽ380ïœã®ç²æ«çæç©ïŒåŸæŸäœïŒã
åŸãããã®åŸæŸäœã«ã€ããŠãéŠæã®æŸåºè©Šéšçµæ
ã¯ç¬¬ïŒè¡šã«ç€ºãéãã§ãã€ãã å®æœäŸ 15 å®æœäŸïŒã«ãããŠçé žååå¿çµäºåŸãã¡ã³ããŒ
ã«ïŒïœãæ·»å ãçŽ15åéãã®ãŸãŸæ¹æãç¶ããåž
åŒéã也ç¥ããããšã«ããçŽ380ïœã®ç²äœçæ
ç©ïŒåŸæŸäœïŒãåŸãããã®åŸæŸäœã«ã€ããŠãéŠæ
ã®æŸåºè©Šéšçµæã¯ç¬¬ïŒè¡šã«ç€ºãéãã§ãã€ãã å®æœäŸ 16 å®æœäŸïŒã«ãã€ãŠåŸãç²äœçæç©380ïœããã¡
ã¿ããŒã«ïŒäžã«ã¡ã³ããŒã«ïŒïœã溶解ããã溶
液äžã«å ¥ãã30åéæ¹æããåŸãåžåŒé也ç¥ã«
ããçŽ380ïœã®ç²äœçæç©ïŒåŸæŸäœïŒãåŸããã
ã®åŸæŸäœã«ã€ããŠã®éŠæã®æŸåºè©Šéšçµæã¯ç¬¬ïŒè¡š
ã«ç€ºãéãã§ãã€ãã æ¯èŒäŸ ïŒ ã¡ã¿ããŒã«ïŒã«ã¡ã³ããŒã«ïŒïœã溶解ããã
溶液äžã«ãçµæ¶æ§çé žã«ã«ã·ãŠã ïŒçœç³å·¥æ¥è£œ
ããã¯ã€ãã³ïŒ°â10ããã«ã«ãµã€ãçµæ¶ïŒ380ïœã
å ¥ããçŽ30åéæ¹æããåŸãåžåŒé也ç¥ã«ãã
çŽ380ïœã®ç²æ«ãåŸãããã®ç²äœã«ã€ããŠã®éŠæ
ã®æŸåºè©Šéšçµæã¯ç¬¬ïŒè¡šã«ç€ºãéãã§ãã€ãã ïŒéŠæã®æŸåºè©ŠéšïŒ è©Šæç²äœ10ïœãã¬ã©ã¹è£œã·ã€ãŒã¬ã«åãããã
ã湿床65ïŒ ã枩床20âã®ææž©æ湿宀ã«ä¿ã¡éŠãã®
çµæå€åã調ã¹ããçµæã第ïŒè¡šã«ç€ºãã
ã¡ã³ããŒã«ïŒïœåã³ã¡ã¿ããŒã«ïŒãçšãçé žå
åå¿ãè¡ãªãçŽ380ïœã®ç²æ«çæç©ïŒåŸæŸäœïŒã
åŸãããã®åŸæŸäœã«ã€ããŠãéŠæã®æŸåºè©Šéšçµæ
ã¯ç¬¬ïŒè¡šã«ç€ºãéãã§ãã€ãã å®æœäŸ 15 å®æœäŸïŒã«ãããŠçé žååå¿çµäºåŸãã¡ã³ããŒ
ã«ïŒïœãæ·»å ãçŽ15åéãã®ãŸãŸæ¹æãç¶ããåž
åŒéã也ç¥ããããšã«ããçŽ380ïœã®ç²äœçæ
ç©ïŒåŸæŸäœïŒãåŸãããã®åŸæŸäœã«ã€ããŠãéŠæ
ã®æŸåºè©Šéšçµæã¯ç¬¬ïŒè¡šã«ç€ºãéãã§ãã€ãã å®æœäŸ 16 å®æœäŸïŒã«ãã€ãŠåŸãç²äœçæç©380ïœããã¡
ã¿ããŒã«ïŒäžã«ã¡ã³ããŒã«ïŒïœã溶解ããã溶
液äžã«å ¥ãã30åéæ¹æããåŸãåžåŒé也ç¥ã«
ããçŽ380ïœã®ç²äœçæç©ïŒåŸæŸäœïŒãåŸããã
ã®åŸæŸäœã«ã€ããŠã®éŠæã®æŸåºè©Šéšçµæã¯ç¬¬ïŒè¡š
ã«ç€ºãéãã§ãã€ãã æ¯èŒäŸ ïŒ ã¡ã¿ããŒã«ïŒã«ã¡ã³ããŒã«ïŒïœã溶解ããã
溶液äžã«ãçµæ¶æ§çé žã«ã«ã·ãŠã ïŒçœç³å·¥æ¥è£œ
ããã¯ã€ãã³ïŒ°â10ããã«ã«ãµã€ãçµæ¶ïŒ380ïœã
å ¥ããçŽ30åéæ¹æããåŸãåžåŒé也ç¥ã«ãã
çŽ380ïœã®ç²æ«ãåŸãããã®ç²äœã«ã€ããŠã®éŠæ
ã®æŸåºè©Šéšçµæã¯ç¬¬ïŒè¡šã«ç€ºãéãã§ãã€ãã ïŒéŠæã®æŸåºè©ŠéšïŒ è©Šæç²äœ10ïœãã¬ã©ã¹è£œã·ã€ãŒã¬ã«åãããã
ã湿床65ïŒ ã枩床20âã®ææž©æ湿宀ã«ä¿ã¡éŠãã®
çµæå€åã調ã¹ããçµæã第ïŒè¡šã«ç€ºãã
ãè¡šã
å®æœäŸ 17
å®æœäŸïŒã«ãããŠçé
žååå¿çµäºåŸãã²ã©ããª
ãŒã«ïŒéŠæïŒ38ïœãæ·»å ããçŽ15åéãã®ãŸãŸæ¹
æãç¶ããåžåŒé也ç¥ããããšã«ããçŽ410ïœ
ã®ç²äœçæç©ïŒåŸæŸäœïŒãåŸããåŸãããè©Šæã
ã¿ã«ã¯åã³ã¹ãã¢ãªã³é žãã°ãã·ãŠã ãšæ··åãã
ãã¬ã°ã©ã³ã¹ããŠããŒã調補ãããã®éŠæ°ã®æç¶
æ§ã«ã€ããŠè©Šéšãããçµæã第ïŒè¡šã«ç€ºããã æ¯èŒäŸ ïŒ ã¿ã«ã¯ãã¹ãã¢ãªã³é žãã°ãã·ãŠã ãçµæ¶æ§ç
é žã«ã«ã·ãŠã ïŒçœç³å·¥æ¥æ ªè£œãPCãã«ã«ãµã€ã
çµæ¶ïŒåã³ã²ã©ããªãŒã«ãåã 65ïŒïŒïŒ27ïŒïŒ
ïŒééæ¯ïŒã®å²åã§æ··åããŠãã¬ã°ã©ã³ã¹ããŠã
ãŒã調補ãããã®éŠæ°ã®æç¶æ§ã«ã€ããŠè©Šéšã
ããçµæã第ïŒè¡šã«ç€ºããã
ãŒã«ïŒéŠæïŒ38ïœãæ·»å ããçŽ15åéãã®ãŸãŸæ¹
æãç¶ããåžåŒé也ç¥ããããšã«ããçŽ410ïœ
ã®ç²äœçæç©ïŒåŸæŸäœïŒãåŸããåŸãããè©Šæã
ã¿ã«ã¯åã³ã¹ãã¢ãªã³é žãã°ãã·ãŠã ãšæ··åãã
ãã¬ã°ã©ã³ã¹ããŠããŒã調補ãããã®éŠæ°ã®æç¶
æ§ã«ã€ããŠè©Šéšãããçµæã第ïŒè¡šã«ç€ºããã æ¯èŒäŸ ïŒ ã¿ã«ã¯ãã¹ãã¢ãªã³é žãã°ãã·ãŠã ãçµæ¶æ§ç
é žã«ã«ã·ãŠã ïŒçœç³å·¥æ¥æ ªè£œãPCãã«ã«ãµã€ã
çµæ¶ïŒåã³ã²ã©ããªãŒã«ãåã 65ïŒïŒïŒ27ïŒïŒ
ïŒééæ¯ïŒã®å²åã§æ··åããŠãã¬ã°ã©ã³ã¹ããŠã
ãŒã調補ãããã®éŠæ°ã®æç¶æ§ã«ã€ããŠè©Šéšã
ããçµæã第ïŒè¡šã«ç€ºããã
ãè¡šã
å°ç¬¬ïŒè¡šã«ãããéŠæ°ã®æç¶æ§ã¯ãå調補ãã
ãã¬ã°ã©ã³ã¹ããŠããŒãå ¥æµŽåŸã®ïŒäººã®èº«äœã«é©
å®æ£åžããäžå®æéçµéæ¯ã®éŠæ°ã®æç¡ã確èªã
ãããšã«ããæ±ãããã®ã§ããã å®æœäŸ 18 å®æœäŸïŒã«ãããŠçé žååå¿çµäºåŸãã¡ãã¬ã³
ãã«ãŒïŒææïŒïŒïœãæ·»å ããŠãçŽ15åéãã®ãŸ
ãŸæ¹æãç¶ããåžåŒé也ç¥ããããšã«ããçŽ
380ïœã®ç²äœçæç©ïŒåŸæŸäœïŒãåŸããåŸããã
è©Šæã®ãã¡100ïœãïŒã®æ°Žã«æžæ¿ãããäžå®çµ
éæéæ¯ã«ãµã³ãã«ãååºãã也ç¥ããŠãã®ç²äœ
ã®çœè²åºŠã枬å®ããã¯ããã«åŸãããçæç©ã®çœ
è²åºŠã«å¯Ÿããå€åçãæ±ãããçµæã第ïŒè¡šã«ç€º
ãããå°å®æœäŸïŒã§åŸãã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·
ãŠã ç²æ«ïŒæè²åïŒã®çœè²åºŠã¯95ã§ãã€ãã æ¯èŒäŸ ïŒ ã¡ã¿ããŒã«ïŒäžã«ã¡ãã¬ã³ãã«ãŒïŒïœã溶解
ããã溶液äžã«çµæ¶æ§çé žã«ã«ã·ãŠã ïŒçœç³å·¥æ¥
補ããã¯ã€ãã³ïŒ°â10ãã«ã«ãµã€ãçµæ¶ããã®çœ
è²åºŠã¯95ã§ããïŒ380ïœãå ¥ããçŽ30åéæ¹æã
ãåŸãåžåŒé也ç¥ã«ããçŽ380ïœã®ç²äœãåŸãã ãã®ç²äœã«ã€ããŠå®æœäŸ18ãšåæ§ã®è©Šéšãè¡ãª
ã€ãçµæã第ïŒè¡šã«ç€ºãã
ãã¬ã°ã©ã³ã¹ããŠããŒãå ¥æµŽåŸã®ïŒäººã®èº«äœã«é©
å®æ£åžããäžå®æéçµéæ¯ã®éŠæ°ã®æç¡ã確èªã
ãããšã«ããæ±ãããã®ã§ããã å®æœäŸ 18 å®æœäŸïŒã«ãããŠçé žååå¿çµäºåŸãã¡ãã¬ã³
ãã«ãŒïŒææïŒïŒïœãæ·»å ããŠãçŽ15åéãã®ãŸ
ãŸæ¹æãç¶ããåžåŒé也ç¥ããããšã«ããçŽ
380ïœã®ç²äœçæç©ïŒåŸæŸäœïŒãåŸããåŸããã
è©Šæã®ãã¡100ïœãïŒã®æ°Žã«æžæ¿ãããäžå®çµ
éæéæ¯ã«ãµã³ãã«ãååºãã也ç¥ããŠãã®ç²äœ
ã®çœè²åºŠã枬å®ããã¯ããã«åŸãããçæç©ã®çœ
è²åºŠã«å¯Ÿããå€åçãæ±ãããçµæã第ïŒè¡šã«ç€º
ãããå°å®æœäŸïŒã§åŸãã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·
ãŠã ç²æ«ïŒæè²åïŒã®çœè²åºŠã¯95ã§ãã€ãã æ¯èŒäŸ ïŒ ã¡ã¿ããŒã«ïŒäžã«ã¡ãã¬ã³ãã«ãŒïŒïœã溶解
ããã溶液äžã«çµæ¶æ§çé žã«ã«ã·ãŠã ïŒçœç³å·¥æ¥
補ããã¯ã€ãã³ïŒ°â10ãã«ã«ãµã€ãçµæ¶ããã®çœ
è²åºŠã¯95ã§ããïŒ380ïœãå ¥ããçŽ30åéæ¹æã
ãåŸãåžåŒé也ç¥ã«ããçŽ380ïœã®ç²äœãåŸãã ãã®ç²äœã«ã€ããŠå®æœäŸ18ãšåæ§ã®è©Šéšãè¡ãª
ã€ãçµæã第ïŒè¡šã«ç€ºãã
ãè¡šã
å°äžèšè©Šéšã«ãããçœè²åºŠã¯ãã±ããå
é»çœåºŠ
èšã«ããéãã€ã«ã¿ãŒãçšããŠæž¬å®ããã å®æœäŸ 19 å®æœäŸïŒã«ãããŠçé žååå¿çµäºåŸããžã¡ãã«
ãã¿ã¬ãŒãïŒèãªã©ã®å¿é¿å€ïŒ38ïœãæ·»å ããŠã
çŽ15åéããã®ãŸãŸæ¹æãç¶ããåžåŒé也ç¥ã
ãããšã«ããçŽ400ïœã®ç²äœçæç©ïŒåŸæŸäœïŒã
åŸãããã®è©Šæãã¯ã»ãªã³ã«30ïŒ ïŒééïŒæ··ã蟌
ã¿ãå¿é¿å€ã調補ãããã®å¿é¿åã«ã€ããŠè©Šéšã
ããçµæã第ïŒè¡šã«ç€ºããã æ¯èŒäŸ ïŒ ã¯ã»ãªã³ãçµæ¶æ§çé žã«ã«ã·ãŠã ïŒçœç³å·¥æ¥è£œ
ããã¯ã€ãã³ïŒ°â10ãã«ã«ãµã€ãçµæ¶ïŒåã³ãžã¡
ãã«ãã¿ã¬ãŒããåã 70ïŒ27ïŒïŒïŒééæ¯ïŒã®å²
åã§æ··åããå¿é¿å€ã調補ããã®å¿é¿åã«ã€ããŠ
è©Šéšãããçµæã第ïŒè¡šã«ç€ºããã
èšã«ããéãã€ã«ã¿ãŒãçšããŠæž¬å®ããã å®æœäŸ 19 å®æœäŸïŒã«ãããŠçé žååå¿çµäºåŸããžã¡ãã«
ãã¿ã¬ãŒãïŒèãªã©ã®å¿é¿å€ïŒ38ïœãæ·»å ããŠã
çŽ15åéããã®ãŸãŸæ¹æãç¶ããåžåŒé也ç¥ã
ãããšã«ããçŽ400ïœã®ç²äœçæç©ïŒåŸæŸäœïŒã
åŸãããã®è©Šæãã¯ã»ãªã³ã«30ïŒ ïŒééïŒæ··ã蟌
ã¿ãå¿é¿å€ã調補ãããã®å¿é¿åã«ã€ããŠè©Šéšã
ããçµæã第ïŒè¡šã«ç€ºããã æ¯èŒäŸ ïŒ ã¯ã»ãªã³ãçµæ¶æ§çé žã«ã«ã·ãŠã ïŒçœç³å·¥æ¥è£œ
ããã¯ã€ãã³ïŒ°â10ãã«ã«ãµã€ãçµæ¶ïŒåã³ãžã¡
ãã«ãã¿ã¬ãŒããåã 70ïŒ27ïŒïŒïŒééæ¯ïŒã®å²
åã§æ··åããå¿é¿å€ã調補ããã®å¿é¿åã«ã€ããŠ
è©Šéšãããçµæã第ïŒè¡šã«ç€ºããã
ãè¡šã
å°ãã®è©Šéšã«ãããŠèã®å¿é¿åã¯æ¬¡ã®éã枬å®
ãããå³ã¡å調補ããè¬å€ãããããïŒäººã®äººã®
æåã³èã«ãŸãã¹ããªãèããã蟌ã¿èã®å€ãçº
çããŠããå Žæã«ç«ã¡ãäžå®çµéæéæ¯ã®èã®å¯
ãã€ãç¶æ³ã芳å¯ããã å®æœäŸ 20 å®æœäŸïŒã«ãããŠçé žååå¿çµäºåŸããã³ãŸã
ãªã¢ãŸãŒã«ïŒé²éå€ïŒ38ïœãæ·»å ããŠãçŽ15åé
ãã®ãŸãŸæ¹æãç¶ããåžåŒé也ç¥ããããšã«ã
ãçŽ400ïœã®ç²äœçæç©ïŒåŸæŸäœïŒãåŸããåŸã
ããåŸæŸäœã«ã€ããŠã®é²éè©Šéšã®çµæã第ïŒè¡šã«
瀺ããã æ¯èŒäŸ ïŒ çµæ¶æ§çé žã«ã«ã·ãŠã ïŒçœç³å·¥æ¥è£œãPCãã«
ã«ãµã€ãçµæ¶ïŒããã³ãã³ãŸããªã¢ãŸãŒã«ãåã
90ïŒ10ïŒééæ¯ïŒã®å²åã§æ··åããé²éå€ã調補
ãããã®é²éè©Šéšã®çµæã第ïŒè¡šã«ç€ºããã åèäŸ é²éå€ãªãã®å Žåã«ã€ããŠã®é²éè©Šéšã®çµæã
第ïŒè¡šã«ç€ºããã
ãããå³ã¡å調補ããè¬å€ãããããïŒäººã®äººã®
æåã³èã«ãŸãã¹ããªãèããã蟌ã¿èã®å€ãçº
çããŠããå Žæã«ç«ã¡ãäžå®çµéæéæ¯ã®èã®å¯
ãã€ãç¶æ³ã芳å¯ããã å®æœäŸ 20 å®æœäŸïŒã«ãããŠçé žååå¿çµäºåŸããã³ãŸã
ãªã¢ãŸãŒã«ïŒé²éå€ïŒ38ïœãæ·»å ããŠãçŽ15åé
ãã®ãŸãŸæ¹æãç¶ããåžåŒé也ç¥ããããšã«ã
ãçŽ400ïœã®ç²äœçæç©ïŒåŸæŸäœïŒãåŸããåŸã
ããåŸæŸäœã«ã€ããŠã®é²éè©Šéšã®çµæã第ïŒè¡šã«
瀺ããã æ¯èŒäŸ ïŒ çµæ¶æ§çé žã«ã«ã·ãŠã ïŒçœç³å·¥æ¥è£œãPCãã«
ã«ãµã€ãçµæ¶ïŒããã³ãã³ãŸããªã¢ãŸãŒã«ãåã
90ïŒ10ïŒééæ¯ïŒã®å²åã§æ··åããé²éå€ã調補
ãããã®é²éè©Šéšã®çµæã第ïŒè¡šã«ç€ºããã åèäŸ é²éå€ãªãã®å Žåã«ã€ããŠã®é²éè©Šéšã®çµæã
第ïŒè¡šã«ç€ºããã
ãè¡šã
ïŒé²éè©ŠéšïŒ
çŽåŸ300mmã®ãã·ã±ãŒã¿ãŒïŒèãªãïŒã®åºéš
ã«åŸæŸäœè©Šæ200ïœãå ¥ãæ£æ¿ã®äžã«å§å»¶éŒæ¿â»
ã眮ãããã®ãŸãŸæ¹¿åºŠ65ïŒ ã枩床30âã®ææž©æ湿
床ã«ä¿æãããµãã®ããããããŸã§ã®ç¶æ³ã芳å¯
ããã â»JIS G3141èŠå®ã®éŒæ¿ãïŒééïŒ é£å¡©æ°Žã«ïŒ
ç§é浞挬ããŠåŒäžããŠä¹Ÿç¥ãããã®ã䜿çšã
ã«åŸæŸäœè©Šæ200ïœãå ¥ãæ£æ¿ã®äžã«å§å»¶éŒæ¿â»
ã眮ãããã®ãŸãŸæ¹¿åºŠ65ïŒ ã枩床30âã®ææž©æ湿
床ã«ä¿æãããµãã®ããããããŸã§ã®ç¶æ³ã芳å¯
ããã â»JIS G3141èŠå®ã®éŒæ¿ãïŒééïŒ é£å¡©æ°Žã«ïŒ
ç§é浞挬ããŠåŒäžããŠä¹Ÿç¥ãããã®ã䜿çšã
第ïŒå³ã¯å®æœäŸïŒã§åŸãæ¬çºæã¢ã¢ã«ãã¢ã¹ç
é žã«ã«ã·ãŠã ç²äœã®ïŒžç·åæå³ã第ïŒå³ã¯åç²æ«
ã200âïŒæéä¿æåŸã®ïŒžç·åæå³ã第ïŒå³ã¯å
ç²æ«ã®400âã§ïŒæéçŒæããåŸã®ïŒžç·åæå³å
ã³ç¬¬ïŒå³ã¯åç²æ«ã®ç€ºå·®ç±ã»ç±å€©ç§€æž¬å®å³ã倫ã
瀺ãã
é žã«ã«ã·ãŠã ç²äœã®ïŒžç·åæå³ã第ïŒå³ã¯åç²æ«
ã200âïŒæéä¿æåŸã®ïŒžç·åæå³ã第ïŒå³ã¯å
ç²æ«ã®400âã§ïŒæéçŒæããåŸã®ïŒžç·åæå³å
ã³ç¬¬ïŒå³ã¯åç²æ«ã®ç€ºå·®ç±ã»ç±å€©ç§€æž¬å®å³ã倫ã
瀺ãã
Claims (1)
- ãç¹èš±è«æ±ã®ç¯å²ã ïŒ ã«ã«ã·ãŠã ååç©ãã¢ã«ã³ãŒã«åªäœç³»å ã§ç
é žååå¿ãããŠçæ¯é1.6ã2.5ãå±æç1.45ã
1.57ãBETæ³ã«ããæ¯è¡šé¢ç©20ã600m2ïŒïœåã³
10ïœïŒ100mlH2O氎溶液ã®PH6.0ã8.0ãæãç¡å®
圢ã§ããã200âãïŒæéã®ãªãŒãã³å ç±ã«ãã
å®å®ã§ããçé žã«ã«ã·ãŠã ãåŸãããšãç¹åŸŽãšã
ãã¢ã¢ã«ãã¢ã¹çé žã«ã«ã·ãŠã ã®è£œé æ¹æ³ã ïŒ ã«ã«ã·ãŠã ååç©ãé žåã«ã«ã·ãŠã ãæ°Žé žå
ã«ã«ã·ãŠã ãéå±ã«ã«ã·ãŠã ãæ°Žé žåã«ã«ã·ãŠ
ã ãããã²ã³åã«ã«ã·ãŠã åã³ç¡é žã«ã«ã·ãŠã ã
ãéžæãããç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒé ã«èšèŒã®æ¹
æ³ã ïŒ çé žååå¿ãäºé žåççŽ åã¯çé žå¡©ååç©ã
çšããŠè¡ãããç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒé ã«èšèŒã®æ¹
æ³ã ïŒ çé žååå¿ããç¡é žã¢ã³ã¢ããŠã ãé ¢é žã¢ã³
ã¢ããŠã åã³å¡©åã¢ã³ã¢ããŠã ããéžæãããå
å¿ä¿é²å€ã®ååšäžã«è¡ãªãããç¹èš±è«æ±ã®ç¯å²ç¬¬
ïŒé ã«èšèŒã®æ¹æ³ã
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17229682A JPS5964527A (ja) | 1982-09-29 | 1982-09-29 | ã¢ã¢ã«ãã¡ã¹çé žã«ã«ã·ãŠã ã®è£œé æ¹æ³ |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17229682A JPS5964527A (ja) | 1982-09-29 | 1982-09-29 | ã¢ã¢ã«ãã¡ã¹çé žã«ã«ã·ãŠã ã®è£œé æ¹æ³ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5964527A JPS5964527A (ja) | 1984-04-12 |
| JPH0216244B2 true JPH0216244B2 (ja) | 1990-04-16 |
Family
ID=15939294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP17229682A Granted JPS5964527A (ja) | 1982-09-29 | 1982-09-29 | ã¢ã¢ã«ãã¡ã¹çé žã«ã«ã·ãŠã ã®è£œé æ¹æ³ |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5964527A (ja) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10125262B2 (en) | 2012-08-07 | 2018-11-13 | Amorphical Ltd. | Method for producing stabilized amorphous calcium carbonate |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3417393C2 (de) * | 1984-05-10 | 1986-10-30 | Adolf Prof. Dr. 3220 Alfeld Knappwost | Mittel zur Anhebung des pH-Werts der Zahnplaque und Verfahren zu deren Herstellung |
| US5460803A (en) * | 1989-05-24 | 1995-10-24 | American Dental Association Health Foundation | Methods and compositions for mineralizing and fluoridating calcified tissues |
| JPH0822910B2 (ja) * | 1990-01-08 | 1996-03-06 | ååœåæå·¥æ¥æ ªåŒäŒç€Ÿ | çé žã«ã«ã·ãŠã çµæç©ãå«æããé«ååçµæç©ã®è£œæ³ |
| US5690897A (en) * | 1994-11-21 | 1997-11-25 | Minerals Technologies Inc. | Method for purification of calcium carbonate |
| US20030161894A1 (en) * | 2001-09-05 | 2003-08-28 | 3P Technologies Ltd. | Precipitated aragonite and a process for producing it |
| US6685908B1 (en) * | 2000-03-06 | 2004-02-03 | 3P Technologies Ltd. | Precipitated aragonite and a process for producing it |
| AU2001235934A1 (en) * | 2000-03-06 | 2001-09-17 | 3P Technologies Ltd. | Precipitated aragonite and a process for producing it |
| KR20020082813A (ko) * | 2002-09-06 | 2002-10-31 | íêµì§ì§ììì°êµ¬ì | ìíì¬-ìížë êžëŠ¬ìœê³ììì íì°í ë°ìì ìŽì©íì¬ì ì¡°ë ë¹ì ì§ íì°ì¹Œìì íì²ëŠ¬ ë°©ë² |
| DE102007018975A1 (de) * | 2007-04-07 | 2008-10-09 | Schaefer Kalk Gmbh & Co. Kg | Kugelförmige Calciumcarbonat-Teilchen |
| EP2168572A1 (en) | 2008-09-30 | 2010-03-31 | Omya Development Ag | New controlled release active agent carrier |
| EP2421507B1 (en) * | 2009-04-24 | 2019-01-23 | Fertin Pharma A/S | Chewing gum and particulate material for controlled release of active ingredients |
| JP5429747B2 (ja) * | 2009-12-04 | 2014-02-26 | åŠæ ¡æ³äººæ¥æ¬å€§åŠ | 埮å°ç²ãããªãååç©ã®è£œé æ¹æ³ãéæ¶è³ªçé žã«ã«ã·ãŠã |
| BE1021564B1 (fr) * | 2013-01-30 | 2015-12-14 | S.A. Lhoist Recherche Et Developpement | Procede de preparation de gel de carbonate de calcium et produit ainsi obtenu. |
| CN105980310B (zh) * | 2014-02-28 | 2018-11-06 | äžžå°Ÿéæ ªåŒäŒç€Ÿ | æ èçšç¢³é žéå¡«æ以åå«æ该填æçæ èç»åç© |
| CN113651350B (zh) * | 2021-09-17 | 2023-08-01 | æ¹åå·¥äžå€§åŠ | äžç§åšé溶åäžå¶å€çš³å®å€åç¶æ å®åœ¢ç¢³é žéçæ¹æ³ |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56124368A (en) * | 1980-02-25 | 1981-09-30 | Monsanto Co | Stabilized amorphous calcium carbonate |
-
1982
- 1982-09-29 JP JP17229682A patent/JPS5964527A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56124368A (en) * | 1980-02-25 | 1981-09-30 | Monsanto Co | Stabilized amorphous calcium carbonate |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10125262B2 (en) | 2012-08-07 | 2018-11-13 | Amorphical Ltd. | Method for producing stabilized amorphous calcium carbonate |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5964527A (ja) | 1984-04-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPH0216244B2 (ja) | ||
| JP3419787B2 (ja) | äžç©ºã·ãªã«ç²åã®è£œé æ¹æ³ | |
| TWI382022B (zh) | äºç²æ°§åºåçæïŒïœïœïœïœ ïœïœïœïœ ïœïŒä¹äžé ®æº¶ååç©åå ¶è£œæ³ | |
| DE2225973B1 (de) | Verfahren zum Beschichten von nicht porösem Material mit einer porösen Siliciumdioxidschicht | |
| DE4140858A1 (de) | Pharmazeutische mittel | |
| CH655188A5 (fr) | Sensibilisateur d'oxydation par photosensibilisation en systeme heterogene. | |
| EP2626464B1 (en) | Composition for paper deacidification, process to obtain it and method for its application | |
| JPS63178826A (ja) | è±èå€ | |
| ES2352541T3 (es) | Composición acuosa que contiene un carbonato de zirconio y de una sal de metal alcalino y un haluro de amonio, asà como su uso. | |
| US2400709A (en) | Process of preparing a gel product for absorption of poisonous gases | |
| DE1266742B (de) | Verfahren zur Herstellung von kieselsaeuregebundenen Formkoerpern aus kristallinen zeolithischen Molekularsieben mit hoher Nassabriebfestigkeit | |
| JPH0426893B2 (ja) | ||
| US20040063961A1 (en) | Crystalline forms of cerivastatin sodium | |
| Kuhnt et al. | Controlled fragrance release from galactose-based pro-fragrances | |
| EP2999456B1 (en) | Microcapsules containing a gas-releasing photolabile compound and uses thereof | |
| JP2017532428A (ja) | 倧æ°ãªãŸã³æ¿åºŠãäœäžãããããã®çµæç©ããã³æ¹æ³ | |
| JPH04290546A (ja) | æªèã¬ã¹åžçå€ | |
| DE1198349B (de) | Verfahren zur Herstellung von lagerfaehigem, kristallisiertem Kaliumsorbat aus Sorbinsaeure | |
| JPS5930863A (ja) | å®å®ãªçŸ€éåã³ãã®è£œé æ³ | |
| Oselâskaya et al. | Competing Role of Water in Inclusion of Indomethacin and Volatile Organic Compounds by Native Cyclodextrins | |
| CN115381964B (zh) | å线é -ç¯ç³ç²Ÿå åç©çæ¹è¿å¶å€æ¹æ³ | |
| JP3284226B2 (ja) | 掻æ§çãªãŸã³å解æåã³ãã®è£œé æ¹æ³ | |
| JPH0333022B2 (ja) | ||
| JP3903891B2 (ja) | æ¿ç¶çé žã«ã«ã·ãŠã ç³»ã®çç¶è€åäœã®è£œé æ¹æ³ | |
| FR2523585A1 (fr) | Procede de stabilisation de carboxymethylcellulose irradiee |