JPH0156051B2 - - Google Patents

Info

Publication number
JPH0156051B2
JPH0156051B2 JP55153947A JP15394780A JPH0156051B2 JP H0156051 B2 JPH0156051 B2 JP H0156051B2 JP 55153947 A JP55153947 A JP 55153947A JP 15394780 A JP15394780 A JP 15394780A JP H0156051 B2 JPH0156051 B2 JP H0156051B2
Authority
JP
Japan
Prior art keywords
hbsag
cells
temperature
occurs
caffeine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP55153947A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5679625A (en
Inventor
Jee Makuaree Uiriamu
Zetsudo Maakusu Henrii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS5679625A publication Critical patent/JPS5679625A/ja
Publication of JPH0156051B2 publication Critical patent/JPH0156051B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP15394780A 1979-11-02 1980-11-04 Virus proliferation Granted JPS5679625A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/090,169 US4301250A (en) 1979-11-02 1979-11-02 Method of producing hepatitis B surface antigen

Publications (2)

Publication Number Publication Date
JPS5679625A JPS5679625A (en) 1981-06-30
JPH0156051B2 true JPH0156051B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-11-28

Family

ID=22221612

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15394780A Granted JPS5679625A (en) 1979-11-02 1980-11-04 Virus proliferation

Country Status (10)

Country Link
US (1) US4301250A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0028567B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5679625A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE10806T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3069846D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK462280A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES496445A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR70783B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE50695B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT71977B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1177753A (en) * 1980-03-27 1984-11-13 Paul M. Keller Method of growing hepatitis b surface antigen background of the invention
US4393133A (en) * 1980-06-12 1983-07-12 The Wistar Institute Of Anatomy And Biology Human hepatoma derived cell line, process for preparation thereof, and uses therefor
US4301249A (en) * 1980-07-23 1981-11-17 Merck & Co., Inc. High titer production of hepatitis A virus
US4416986A (en) * 1981-01-16 1983-11-22 Merck & Co., Inc. Methods of producing HBsAg
AU8746582A (en) * 1981-09-02 1983-03-10 Biogen N.V. Hepatitis b virus e type antigen
US4714613A (en) * 1982-09-30 1987-12-22 The Albert Einstein College Of Medicine Of Yeshiva University Method of suppressing cell growth by immunotherapy
GB8321789D0 (en) * 1983-08-12 1983-09-14 Biogen Nv Vaccines and compositions against hepatitis
JPS6078999A (ja) * 1983-10-05 1985-05-04 Chemo Sero Therapeut Res Inst HBs抗原の精製方法
US5498537A (en) * 1994-03-09 1996-03-12 Cellco, Inc. Serum-free production of packaged viral vector
CN104962525A (zh) * 2007-05-04 2015-10-07 巴克斯特国际公司 用于病毒增殖的两阶段温度分布

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821087A (en) * 1972-05-18 1974-06-28 Dedrick R Cell culture on semi-permeable tubular membranes
JPS4940925A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1972-08-26 1974-04-17
JPS5531762B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1973-03-28 1980-08-20
JPS5127730A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1974-08-31 1976-03-08 Tokyo Shibaura Electric Co
JPS5822008B2 (ja) * 1975-08-07 1983-05-06 デユフアル・インテルナチオナル・レセ−ルフ・ベ−・ヴエ− 猫のヘルペスウイルスのワクチン
US4164566A (en) * 1978-08-17 1979-08-14 Merck & Co., Inc. Hepatitis a virus cell culture in vitro

Also Published As

Publication number Publication date
ATE10806T1 (de) 1985-01-15
EP0028567B1 (en) 1984-12-19
US4301250A (en) 1981-11-17
DE3069846D1 (en) 1985-01-31
ES8202059A1 (es) 1982-01-16
PT71977B (en) 1982-03-31
IE802262L (en) 1981-05-02
EP0028567A3 (en) 1982-05-26
GR70783B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-03-23
PT71977A (en) 1980-11-01
IE50695B1 (en) 1986-06-25
EP0028567A2 (en) 1981-05-13
JPS5679625A (en) 1981-06-30
ES496445A0 (es) 1982-01-16
DK462280A (da) 1981-05-03

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