JPH0142275B2 - - Google Patents

Info

Publication number
JPH0142275B2
JPH0142275B2 JP58033682A JP3368283A JPH0142275B2 JP H0142275 B2 JPH0142275 B2 JP H0142275B2 JP 58033682 A JP58033682 A JP 58033682A JP 3368283 A JP3368283 A JP 3368283A JP H0142275 B2 JPH0142275 B2 JP H0142275B2
Authority
JP
Japan
Prior art keywords
erythromycin
acid
dihydro
isopropylidene
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP58033682A
Other languages
English (en)
Japanese (ja)
Other versions
JPS58159500A (ja
Inventor
Robaato Hausuku Jeemuzu
Kurisuteian Saiauorino Furanku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Original Assignee
Pfizer Corp Belgium
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium filed Critical Pfizer Corp Belgium
Publication of JPS58159500A publication Critical patent/JPS58159500A/ja
Publication of JPH0142275B2 publication Critical patent/JPH0142275B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP58033682A 1982-03-01 1983-03-01 エリスロマイシンａおよびエピ−エリスロマイシンａの９−ジヒドロ−１１，１２−ケタ−ル誘導体 Granted JPS58159500A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US353548 1982-03-01
US06/353,548 US4382086A (en) 1982-03-01 1982-03-01 9-Dihydro-11,12-ketal derivatives of erythromycin A and epi-erythromycin A

Publications (2)

Publication Number Publication Date
JPS58159500A JPS58159500A (ja) 1983-09-21
JPH0142275B2 true JPH0142275B2 (en, 2012) 1989-09-11

Family

ID=23389607

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58033682A Granted JPS58159500A (ja) 1982-03-01 1983-03-01 エリスロマイシンａおよびエピ−エリスロマイシンａの９−ジヒドロ−１１，１２−ケタ−ル誘導体

Country Status (8)

Country Link
US (1) US4382086A (en, 2012)
EP (1) EP0087916B1 (en, 2012)
JP (1) JPS58159500A (en, 2012)
DE (1) DE3361453D1 (en, 2012)
DK (1) DK159853C (en, 2012)
GR (1) GR77921B (en, 2012)
IE (1) IE54431B1 (en, 2012)
YU (1) YU42841B (en, 2012)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8421429D0 (en) * 1984-08-23 1984-09-26 Beecham Group Plc Chemical compounds
EP0184921A3 (en) * 1984-12-08 1986-10-29 Beecham Group Plc Erythromycin derivatives
US4847242A (en) 1985-03-12 1989-07-11 Beecham Group P.L.C. 11-ether derivatives of erythromycins
US4640910A (en) * 1985-11-12 1987-02-03 Abbott Laboratories Erythromycin A silylated compounds and method of use
US4681872A (en) * 1985-11-12 1987-07-21 Abbott Laboratories Erythromycin A 11,12-carbonate and method of use
WO1992006991A1 (fr) * 1990-10-15 1992-04-30 Taisho Pharmaceutical Co., Ltd. Erythromycine modifiee en 2' ou derive de cette substance
HRP20040849A2 (en) * 2002-02-15 2005-08-31 Synovo Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
US20060069047A1 (en) * 2002-02-15 2006-03-30 Michael Burnet Antibiotic conjugates
CA2476423A1 (en) 2002-02-15 2003-08-28 Sympore Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
PT1532131E (pt) * 2002-08-29 2009-02-18 Pfizer Compostos motilidos
US7211568B2 (en) * 2003-12-18 2007-05-01 Kosan Biosciences Incorporated 9-Desoxoerythromycin compounds as prokinetic agents
CN101228171A (zh) * 2005-07-26 2008-07-23 默克勒有限公司 作为5-脂氧化酶和环加氧酶抑制剂的吡咯里嗪和中氮茚化合物的大环内酯偶联物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2653899A (en) * 1952-04-14 1953-09-29 Lilly Co Eli Erythromycin, its salts, and method of preparation
US3417077A (en) * 1966-05-16 1968-12-17 Lilly Co Eli Erythromycin derivative and process for the preparation thereof
US3884904A (en) * 1973-06-21 1975-05-20 Abbott Lab 11-Substituted erythromycin B derivatives
US3884903A (en) * 1973-06-21 1975-05-20 Abbott Lab 4{41 -Deoxy-4{41 -oxoerythromycin B derivatives
US4150220A (en) * 1977-02-04 1979-04-17 Pfizer Inc. Semi-synthetic 4"-erythromycin A derivatives

Also Published As

Publication number Publication date
EP0087916A1 (en) 1983-09-07
IE830410L (en) 1983-09-01
DK159853B (da) 1990-12-17
DE3361453D1 (en) 1986-01-23
DK159853C (da) 1991-05-13
YU45983A (en) 1986-02-28
EP0087916B1 (en) 1985-12-11
GR77921B (en, 2012) 1984-09-25
YU42841B (en) 1988-12-31
DK96983D0 (da) 1983-02-28
DK96983A (da) 1983-09-02
IE54431B1 (en) 1989-10-11
JPS58159500A (ja) 1983-09-21
US4382086A (en) 1983-05-03

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