JP7829231B2 - マイクロ二相液滴生成デバイス - Google Patents

マイクロ二相液滴生成デバイス

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Publication number
JP7829231B2
JP7829231B2 JP2022563855A JP2022563855A JP7829231B2 JP 7829231 B2 JP7829231 B2 JP 7829231B2 JP 2022563855 A JP2022563855 A JP 2022563855A JP 2022563855 A JP2022563855 A JP 2022563855A JP 7829231 B2 JP7829231 B2 JP 7829231B2
Authority
JP
Japan
Prior art keywords
phase
slit
dispersed phase
dispersed
continuous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2022563855A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2022107898A5 (https=
JPWO2022107898A1 (https=
Inventor
貴志 西迫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Science and Technology Agency
Original Assignee
Japan Science and Technology Agency
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Filing date
Publication date
Application filed by Japan Science and Technology Agency filed Critical Japan Science and Technology Agency
Publication of JPWO2022107898A1 publication Critical patent/JPWO2022107898A1/ja
Publication of JPWO2022107898A5 publication Critical patent/JPWO2022107898A5/ja
Application granted granted Critical
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/302—Micromixers the materials to be mixed flowing in the form of droplets
    • B01F33/3021—Micromixers the materials to be mixed flowing in the form of droplets the components to be mixed being combined in a single independent droplet, e.g. these droplets being divided by a non-miscible fluid or consisting of independent droplets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B01F33/3012—Interdigital streams, e.g. lamellae
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/4105—Methods of emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/414—Emulsifying characterised by the internal structure of the emulsion
    • B01F23/4143—Microemulsions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/414—Emulsifying characterised by the internal structure of the emulsion
    • B01F23/4144—Multiple emulsions, in particular double emulsions, e.g. water in oil in water; Three-phase emulsions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3035—Micromixers using surface tension to mix, move or hold the fluids
    • B01F33/30351—Micromixers using surface tension to mix, move or hold the fluids using hydrophilic/hydrophobic surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B1/00—Devices without movable or flexible elements, e.g. microcapillary devices
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L29/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
    • C08L29/02—Homopolymers or copolymers of unsaturated alcohols
    • C08L29/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0486—Material property information
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2201/00—Properties
    • C08L2201/52—Aqueous emulsion or latex, e.g. containing polymers of a glass transition temperature (Tg) below 20°C

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Computer Hardware Design (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
JP2022563855A 2020-11-20 2021-11-22 マイクロ二相液滴生成デバイス Active JP7829231B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020193256 2020-11-20
JP2020193256 2020-11-20
PCT/JP2021/042781 WO2022107898A1 (ja) 2020-11-20 2021-11-22 マイクロ二相液滴生成デバイス

Publications (3)

Publication Number Publication Date
JPWO2022107898A1 JPWO2022107898A1 (https=) 2022-05-27
JPWO2022107898A5 JPWO2022107898A5 (https=) 2023-07-19
JP7829231B2 true JP7829231B2 (ja) 2026-03-13

Family

ID=81709122

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022563855A Active JP7829231B2 (ja) 2020-11-20 2021-11-22 マイクロ二相液滴生成デバイス

Country Status (5)

Country Link
US (1) US20240017224A1 (https=)
EP (1) EP4249109A4 (https=)
JP (1) JP7829231B2 (https=)
CN (1) CN116457079A (https=)
WO (1) WO2022107898A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024154499A1 (ja) * 2023-01-17 2024-07-25 Ｔｏｐｐａｎホールディングス株式会社 マイクロ流路チップ及びその製造方法
CN219275939U (zh) 2023-03-27 2023-06-30 苏州市乾丰造纸机械制造有限公司 一种圆刀组合体

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005144356A (ja) 2003-11-17 2005-06-09 Tosoh Corp 微小流路構造体及びこれを用いた微小粒子製造方法
JP2012166125A (ja) 2011-02-10 2012-09-06 Tokyo Institute Of Technology ２色性微小液滴の製造方法およびその装置
JP2013503742A (ja) 2009-09-02 2013-02-04 プレジデント アンド フェロウズ オブ ハーバード カレッジ ジャンクションを使用して生成された多重エマルジョン
WO2019168130A1 (ja) 2018-02-28 2019-09-06 国立大学法人東京工業大学 マイクロ液滴・気泡生成デバイス

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60221036T2 (de) * 2001-02-23 2007-10-11 Japan Science And Technology Agency, Kawaguchi Vorrichtung zum Erzeugen von Emulsionen und Mikrokapseln
JP4527384B2 (ja) * 2002-12-06 2010-08-18 綜研化学株式会社 マイクロチャンネルを用いた着色球状粒子の製造方法、およびその製造方法に用いるマイクロチャンネル式製造装置
DE20218972U1 (de) * 2002-12-07 2003-02-13 Ehrfeld Mikrotechnik AG, 55234 Wendelsheim Statischer Laminationsmikrovermischer
JP4166590B2 (ja) * 2003-02-04 2008-10-15 独立行政法人科学技術振興機構 ダブルエマルション・マイクロカプセル生成装置
JP4892743B2 (ja) * 2005-08-31 2012-03-07 国立大学法人 東京大学 微細流路を用いた微小液滴の製造装置
WO2011028764A2 (en) * 2009-09-02 2011-03-10 President And Fellows Of Harvard College Multiple emulsions created using jetting and other techniques
WO2012008497A1 (ja) * 2010-07-13 2012-01-19 国立大学法人東京工業大学 微小液滴の製造装置
JP2012020217A (ja) * 2010-07-13 2012-02-02 Tokyo Institute Of Technology ２色性微小液滴の製造方法
JP6706774B2 (ja) * 2015-10-23 2020-06-10 国立大学法人 東京大学 コアシェル粒子の製造方法
US12138629B2 (en) * 2019-01-31 2024-11-12 Samplix Aps Microfluidic device and a method for provision of double emulsion droplets

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005144356A (ja) 2003-11-17 2005-06-09 Tosoh Corp 微小流路構造体及びこれを用いた微小粒子製造方法
JP2013503742A (ja) 2009-09-02 2013-02-04 プレジデント アンド フェロウズ オブ ハーバード カレッジ ジャンクションを使用して生成された多重エマルジョン
JP2012166125A (ja) 2011-02-10 2012-09-06 Tokyo Institute Of Technology ２色性微小液滴の製造方法およびその装置
WO2019168130A1 (ja) 2018-02-28 2019-09-06 国立大学法人東京工業大学 マイクロ液滴・気泡生成デバイス

Also Published As

Publication number Publication date
WO2022107898A1 (ja) 2022-05-27
CN116457079A (zh) 2023-07-18
EP4249109A1 (en) 2023-09-27
US20240017224A1 (en) 2024-01-18
JPWO2022107898A1 (https=) 2022-05-27
EP4249109A4 (en) 2024-11-13

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