JP7780857B2 - 抗ｐｄ－１抗体を用いる腫瘍の治療方法 - Google Patents

抗ｐｄ－１抗体を用いる腫瘍の治療方法

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Publication number
JP7780857B2
JP7780857B2 JP2019566619A JP2019566619A JP7780857B2 JP 7780857 B2 JP7780857 B2 JP 7780857B2 JP 2019566619 A JP2019566619 A JP 2019566619A JP 2019566619 A JP2019566619 A JP 2019566619A JP 7780857 B2 JP7780857 B2 JP 7780857B2
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antibody
tumor
subject
mutation
stk11
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JP2020522508A5 (enExample
JP2020522508A (ja
Inventor
ロビン・エドワーズ
ウィリアム・ジェイ・ギース
ダニエル・エム・グリーナウォルト
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2019566619A 2017-06-01 2018-06-01 抗ｐｄ－１抗体を用いる腫瘍の治療方法 Active JP7780857B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023127759A JP2023159179A (ja) 2017-06-01 2023-08-04 抗ｐｄ－１抗体を用いる腫瘍の治療方法
JP2025281525A JP2026053613A (ja) 2017-06-01 2025-12-25 抗ｐｄ－１抗体を用いる腫瘍の治療方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762513831P 2017-06-01 2017-06-01
US62/513,831 2017-06-01
PCT/US2018/035670 WO2018223040A1 (en) 2017-06-01 2018-06-01 Methods of treating a tumor using an anti-pd-1 antibody

Related Child Applications (1)

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JP2023127759A Division JP2023159179A (ja) 2017-06-01 2023-08-04 抗ｐｄ－１抗体を用いる腫瘍の治療方法

Publications (3)

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JP2020522508A JP2020522508A (ja) 2020-07-30
JP2020522508A5 JP2020522508A5 (enExample) 2021-07-26
JP7780857B2 true JP7780857B2 (ja) 2025-12-05

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JP2019566619A Active JP7780857B2 (ja) 2017-06-01 2018-06-01 抗ｐｄ－１抗体を用いる腫瘍の治療方法
JP2023127759A Pending JP2023159179A (ja) 2017-06-01 2023-08-04 抗ｐｄ－１抗体を用いる腫瘍の治療方法
JP2025281525A Pending JP2026053613A (ja) 2017-06-01 2025-12-25 抗ｐｄ－１抗体を用いる腫瘍の治療方法

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JP2023127759A Pending JP2023159179A (ja) 2017-06-01 2023-08-04 抗ｐｄ－１抗体を用いる腫瘍の治療方法
JP2025281525A Pending JP2026053613A (ja) 2017-06-01 2025-12-25 抗ｐｄ－１抗体を用いる腫瘍の治療方法

Country Status (6)

Country Link
US (3) US11566073B2 (enExample)
EP (1) EP3630840A1 (enExample)
JP (3) JP7780857B2 (enExample)
KR (2) KR20240149982A (enExample)
CN (2) CN117462668A (enExample)
WO (1) WO2018223040A1 (enExample)

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WO2016176503A1 (en) 2015-04-28 2016-11-03 Bristol-Myers Squibb Company Treatment of pd-l1-negative melanoma using an anti-pd-1 antibody and an anti-ctla-4 antibody
MX392711B (es) 2015-08-11 2025-03-24 Wuxi Biologics Ireland Ltd Anticuerpos anti-pd-1 novedosos.
EP3630840A1 (en) 2017-06-01 2020-04-08 Bristol-Myers Squibb Company Methods of treating a tumor using an anti-pd-1 antibody
US12668635B1 (en) 2017-11-21 2026-06-30 Arcus Biosciences, Inc. Methods of treating solid tumors using an anti-PD-1 antibody or a fragment thereof
SG11202007590TA (en) * 2018-02-13 2020-09-29 Merck Sharp & Dohme Methods for treating cancer with anti-pd-1 antibodies
CN111821434A (zh) * 2019-04-17 2020-10-27 上海君实生物医药科技股份有限公司 抗pd-1抗体在制备治疗实体瘤的药物中的用途
JP2022514952A (ja) * 2018-12-19 2022-02-16 ストラータ オンコロジー， インコーポレイテッド チェックポイント阻害薬応答性がんを有する対象を検出及び処置する方法
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US12275986B2 (en) * 2020-01-06 2025-04-15 Duke University Biomarkers associated with checkpoint immune therapy and methods of using same
CN110923329B (zh) * 2020-02-06 2020-05-12 至本医疗科技（上海）有限公司 Fgfr4点突变在预测非小细胞肺癌患者对免疫检查点抑制剂疗法敏感性中的应用
CN111440822A (zh) * 2020-04-16 2020-07-24 苏州大学附属第二医院 一种突变lats1质粒的构建与应用
CA3196496A1 (en) 2020-10-23 2022-04-28 Laurence David TOMS Lag-3 antagonist therapy for lung cancer
CN112961920A (zh) * 2021-03-24 2021-06-15 臻和(北京)生物科技有限公司 一种预测肝胆肿瘤患者免疫检查点抑制剂联合靶向治疗疗效的方法及产品
JP7806990B2 (ja) * 2021-08-10 2026-01-27 国立大学法人 新潟大学 内胚葉嚢胞の悪性化に関連する遺伝子の検出方法
CN113943806A (zh) * 2021-11-04 2022-01-18 至本医疗科技（上海）有限公司 预测肺腺癌患者对免疫疗法敏感性的生物标志物、应用和装置
WO2023209035A1 (en) * 2022-04-26 2023-11-02 F. Hoffmann-La Roche Ag Methods and systems for predicting cancer therapy response
CN114931637B (zh) * 2022-06-27 2025-02-18 中山大学中山眼科中心 Pdl1抗体在角膜新生血管疾病中的应用
CN115825441B (zh) * 2023-01-30 2023-05-26 上海秤信生物科技有限公司 预测肺癌三期患者的免疫新辅助疗效的自身抗体标志物
AU2024362581A1 (en) * 2023-10-19 2026-04-30 Tesaro, Inc. Methods of treating cancer with anti-pd-1 agents

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Also Published As

Publication number Publication date
US11566073B2 (en) 2023-01-31
JP2026053613A (ja) 2026-03-25
US20230279114A1 (en) 2023-09-07
JP2020522508A (ja) 2020-07-30
KR20240149982A (ko) 2024-10-15
US20200109204A1 (en) 2020-04-09
KR102714702B1 (ko) 2024-10-10
US20250145713A1 (en) 2025-05-08
JP2023159179A (ja) 2023-10-31
WO2018223040A1 (en) 2018-12-06
CN110678483B (zh) 2023-09-22
KR20200014363A (ko) 2020-02-10
EP3630840A1 (en) 2020-04-08
US12227576B2 (en) 2025-02-18
CN110678483A (zh) 2020-01-10
CN117462668A (zh) 2024-01-30

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