JP7658909B2 - 筋ジストロフィー治療薬 - Google Patents
筋ジストロフィー治療薬 Download PDFInfo
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- JP7658909B2 JP7658909B2 JP2021551476A JP2021551476A JP7658909B2 JP 7658909 B2 JP7658909 B2 JP 7658909B2 JP 2021551476 A JP2021551476 A JP 2021551476A JP 2021551476 A JP2021551476 A JP 2021551476A JP 7658909 B2 JP7658909 B2 JP 7658909B2
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- JP
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- group
- alkyl
- optionally substituted
- receptor antagonist
- crth2 receptor
- Prior art date
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Orthopedic Medicine & Surgery (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| PCT/JP2020/037520 WO2021066136A1 (ja) | 2019-10-03 | 2020-10-02 | 筋ジストロフィー治療薬 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005119984A (ja) | 2003-10-14 | 2005-05-12 | Osaka Bioscience Institute | 筋変性疾患の治療用医薬組成物およびそのスクリーニング方法 |
| US20090088400A1 (en) | 2007-09-11 | 2009-04-02 | Puymirat Jack | Prostaglandin e2 modulation and uses thereof |
| WO2017104728A1 (ja) | 2015-12-16 | 2017-06-22 | 国立大学法人東京大学 | 食物アレルギー治療薬 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005119984A (ja) | 2003-10-14 | 2005-05-12 | Osaka Bioscience Institute | 筋変性疾患の治療用医薬組成物およびそのスクリーニング方法 |
| US20090088400A1 (en) | 2007-09-11 | 2009-04-02 | Puymirat Jack | Prostaglandin e2 modulation and uses thereof |
| WO2017104728A1 (ja) | 2015-12-16 | 2017-06-22 | 国立大学法人東京大学 | 食物アレルギー治療薬 |
Non-Patent Citations (2)
| Title |
|---|
| BULIEN, Ditta et al.，The effect of indomethacin on serum and skeletal muscle enzyme activities of dystrophic hamsters，Biochemical Pharmacology，1976年04月15日，Vol. 25, Issue 8，p.981-983 |
| MOHRI, Ikuko et al.，Inhibition of prostaglandin D synthase suppresses muscular necrosis，The American Journal of Pathology，2009年05月，Vol. 174, No. 5，p. 1735-1744 |
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| JPWO2021066136A1 (https=) | 2021-04-08 |
| WO2021066136A1 (ja) | 2021-04-08 |
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