JP7621795B2 - 改善された免疫細胞療法のためのｎｋ阻害物質遺伝子の標的指向遺伝子組み込み - Google Patents

改善された免疫細胞療法のためのｎｋ阻害物質遺伝子の標的指向遺伝子組み込み Download PDF

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JP7621795B2
JP7621795B2 JP2020521596A JP2020521596A JP7621795B2 JP 7621795 B2 JP7621795 B2 JP 7621795B2 JP 2020521596 A JP2020521596 A JP 2020521596A JP 2020521596 A JP2020521596 A JP 2020521596A JP 7621795 B2 JP7621795 B2 JP 7621795B2
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JP2020537528A5 (enExample
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ブライアン ビュッセル
フィリップ ドゥシャトー
アレクサンドル ジュイレラット
ローラン ポアロ
ジュリアン ヴァルトン
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Cellectis SA
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JP2020521596A 2017-10-19 2018-03-09 改善された免疫細胞療法のためのｎｋ阻害物質遺伝子の標的指向遺伝子組み込み Active JP7621795B2 (ja)

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JP2023015050A JP2023055884A (ja) 2017-10-19 2023-02-03 改善された免疫細胞療法のためのｎｋ阻害物質遺伝子の標的指向遺伝子組み込み

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Application Number Priority Date Filing Date Title
EPPCT/EP2017/076798 2017-10-19
PCT/EP2017/076798 WO2018073391A1 (en) 2016-10-19 2017-10-19 Targeted gene insertion for improved immune cells therapy
EPPCT/EP2018/053343 2018-02-09
EP2018053343 2018-02-09
PCT/EP2018/055957 WO2019076486A1 (en) 2017-10-19 2018-03-09 TARGETED GENE INTEGRATION OF NK INHIBITOR GENES FOR ENHANCED IMMUNE CELL THERAPY

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JP2023015050A Pending JP2023055884A (ja) 2017-10-19 2023-02-03 改善された免疫細胞療法のためのｎｋ阻害物質遺伝子の標的指向遺伝子組み込み

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CA (1) CA3084476A1 (enExample)
IL (1) IL273828B2 (enExample)
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AU2018353112B2 (en) 2017-10-19 2024-11-14 Cellectis Targeted gene integration of NK inhibitors genes for improved immune cells therapy
US20200054675A1 (en) 2018-06-01 2020-02-20 Washington University Suppression of cytokine release syndrome in chimeric antigen receptor cell therapy
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CN113939319A (zh) 2019-04-30 2022-01-14 克里斯珀医疗股份公司 靶向cd19的基因工程化t细胞针对b细胞恶性肿瘤的同种异体细胞疗法
CN114007640A (zh) 2019-05-01 2022-02-01 朱诺治疗学股份有限公司 从修饰的cd247基因座表达嵌合受体的细胞、相关多核苷酸和方法
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KR20230024967A (ko) * 2020-06-11 2023-02-21 노파르티스 아게 Zbtb32 억제제 및 이의 용도
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US20230416786A1 (en) 2020-11-30 2023-12-28 Cellectis Sa Use of aminoquinoline compounds for higher gene integration
CN114874983A (zh) * 2020-12-29 2022-08-09 博雅辑因（北京）生物科技有限公司 鉴定t细胞调节基因的方法
US11578309B2 (en) 2020-12-31 2023-02-14 Crispr Therapeutics Ag Universal donor cells
US20240197880A1 (en) * 2021-04-30 2024-06-20 Cellectis S.A. New anti-muc1 cars and gene edited immune cells for solid tumors cancer immunotherapy
MX2023015153A (es) * 2021-07-01 2024-04-16 Ningbo T Maximum Biopharmaceuticals Co Ltd Polipéptido de unión a antígeno que se dirige a b7h3 y aplicación del mismo.
CN117940465A (zh) * 2021-08-12 2024-04-26 苏州克睿基因生物科技有限公司 经修饰的细胞、其制备方法及应用
US20250249100A1 (en) * 2022-04-25 2025-08-07 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for preventing t cell exhaustion
CN115820697B (zh) * 2022-09-23 2024-07-30 中国海洋大学 一种免疫细胞及其制备方法和应用
AU2024259472A1 (en) * 2023-04-20 2025-11-13 Peter Maccallum Cancer Institute Compositions and methods for immunotherapy - ii
WO2024258835A1 (en) * 2023-06-16 2024-12-19 The Trustees Of Columbia University In The City Of New York Removal of endogenous tcr chains for enhanced tcr-based immunotherapies
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