JP7523354B2 - アミノ酸誘導体の製造方法 - Google Patents

アミノ酸誘導体の製造方法 Download PDF

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Publication number
JP7523354B2
JP7523354B2 JP2020549244A JP2020549244A JP7523354B2 JP 7523354 B2 JP7523354 B2 JP 7523354B2 JP 2020549244 A JP2020549244 A JP 2020549244A JP 2020549244 A JP2020549244 A JP 2020549244A JP 7523354 B2 JP7523354 B2 JP 7523354B2
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group
compound represented
general formula
acid
reaction
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JPWO2020059891A5 (https=
JPWO2020059891A1 (ja
Inventor
真人 村井
潤 竹原
大樹 尾門
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API Corp
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API Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
JP2020549244A 2018-09-21 2019-09-24 アミノ酸誘導体の製造方法 Active JP7523354B2 (ja)

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JP2024076378A JP7790473B2 (ja) 2018-09-21 2024-05-09 アミノ酸誘導体の製造方法

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JP2018177774 2018-09-21
JP2018177774 2018-09-21
PCT/JP2019/037399 WO2020059891A1 (ja) 2018-09-21 2019-09-24 アミノ酸誘導体の製造方法

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JPWO2020059891A1 JPWO2020059891A1 (ja) 2021-08-30
JPWO2020059891A5 JPWO2020059891A5 (https=) 2022-10-03
JP7523354B2 true JP7523354B2 (ja) 2024-07-26

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US (3) US11897844B2 (https=)
EP (1) EP3854786B1 (https=)
JP (2) JP7523354B2 (https=)
CN (2) CN119707784A (https=)
WO (1) WO2020059891A1 (https=)

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* Cited by examiner, † Cited by third party
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CN119707784A (zh) * 2018-09-21 2025-03-28 株式会社Api 氨基酸衍生物的制备方法
KR102698832B1 (ko) * 2022-09-14 2024-08-26 김형식 엑토인의 제조방법

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WO2015173779A1 (en) 2014-05-16 2015-11-19 Micro Labs Limited Process for the preparation of teneligliptin and its novel intermediates
WO2017098425A1 (en) 2015-12-11 2017-06-15 Wockhardt Limited 7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide containing compounds and their use in treating bacterial infections
WO2017167218A1 (zh) 2016-03-31 2017-10-05 山东轩竹医药科技有限公司 一种抗菌组合物及其用途

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US20120053350A1 (en) 2009-04-30 2012-03-01 Ian Mangion Preparation of alkyl esters of n-protected oxo-azacycloalkylcarboxylic acids
JP2013516422A (ja) * 2009-12-30 2013-05-13 アビラ セラピューティクス， インコーポレイテッド タンパク質のリガンド−指向性共有的修飾
SI2657234T1 (sl) * 2010-12-22 2017-06-30 Meiji Seika Pharma Co., Ltd. Derivat optično-aktivnega diazabiciklooktana in metoda za njegovo izdelavo
US8772490B2 (en) * 2010-12-22 2014-07-08 Meiji Seika Pharma Co., Ltd. Optically active diazabicyclooctane derivatives and process for preparing the same
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TW201343645A (zh) * 2012-03-30 2013-11-01 Cubist Pharm Inc １，３，４－□二唑及１，３，４－噻二唑β－內醯胺酶抑制劑
US8969570B2 (en) * 2012-03-30 2015-03-03 Cubist Pharmaceuticals, Inc. Beta-lactamase inhibitors
RU2693898C2 (ru) 2012-05-30 2019-07-05 Мейдзи Сейка Фарма Ко., Лтд. НОВЫЙ ИНГИБИТОР бета-ЛАКТАМАЗЫ И СПОСОБ ЕГО ПОЛУЧЕНИЯ
ES2693568T3 (es) * 2012-12-20 2018-12-12 Api Corporation Método para producir un derivado de ácido cis-5-hidroxi-2-piperidincarboxílico, y método para purificar ácido cis-5-hidroxi-2-piperidincarboxílico
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JP6687238B2 (ja) 2013-12-27 2020-04-22 株式会社エーピーアイ コーポレーション ５−ヒドロキシピペリジン−２−カルボン酸の製造方法
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CN106749242B (zh) * 2015-11-23 2021-04-02 上海医药工业研究院 阿维巴坦中间体的制备方法
JOP20190061A1 (ar) * 2016-09-28 2019-03-26 Novartis Ag مثبطات بيتا-لاكتاماز
US20200325139A1 (en) * 2017-12-22 2020-10-15 Assistance Publique-Hopitaux De Paris New antibiotics targeting mycobacteria
CN109970625B (zh) * 2017-12-28 2021-02-26 新发药业有限公司 一种5r-苄氧氨基哌啶-2s-甲酸或其衍生物的制备方法
CN119707784A (zh) * 2018-09-21 2025-03-28 株式会社Api 氨基酸衍生物的制备方法
CN114206851B (zh) * 2019-04-26 2025-02-11 默沙东有限责任公司 可用于制备(2s,5r)-7-氧代-n-哌啶-4-基-6-(硫酸基)-1,6-二氮杂双环[3.2.1]辛烷-2-甲酰胺的中间体的制备方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140275001A1 (en) 2013-03-14 2014-09-18 Cubist Pharmaceuticals, Inc. Crystalline form of a beta-lactamase inhibitor
WO2014200786A1 (en) 2013-06-10 2014-12-18 Merck Sharp & Dohme Corp. Preparation of tert-butyl 4-((1r,2s,5r)-6- (benzyloxy)-7-0x0-1,6-diazabicycl0[3.2.i]octane-2- carboxamido)piperidine-1-carboxylate
WO2015173779A1 (en) 2014-05-16 2015-11-19 Micro Labs Limited Process for the preparation of teneligliptin and its novel intermediates
CN105061425A (zh) 2015-08-13 2015-11-18 广州楷模生物科技有限公司 二氮杂双环辛酮硫酸单酯的合成方法
WO2017098425A1 (en) 2015-12-11 2017-06-15 Wockhardt Limited 7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide containing compounds and their use in treating bacterial infections
WO2017167218A1 (zh) 2016-03-31 2017-10-05 山东轩竹医药科技有限公司 一种抗菌组合物及其用途

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Org. Process. Res. Dev.，2012年，16，409-414
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Tetrahedron Letters，1989年，３０，３１－３４

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US12281074B2 (en) 2025-04-22
EP3854786A1 (en) 2021-07-28
CA3113606A1 (en) 2020-03-26
US12202800B2 (en) 2025-01-21
CN112930338A (zh) 2021-06-08
WO2020059891A1 (ja) 2020-03-26
CN119707784A (zh) 2025-03-28
JP7790473B2 (ja) 2025-12-23
EP3854786C0 (en) 2026-02-18
EP3854786B1 (en) 2026-02-18
US11897844B2 (en) 2024-02-13
JPWO2020059891A1 (ja) 2021-08-30
CN112930338B (zh) 2024-12-24
US20210403427A1 (en) 2021-12-30
EP3854786A4 (en) 2022-09-14
JP2024105463A (ja) 2024-08-06
US20240002340A1 (en) 2024-01-04
US20240150292A1 (en) 2024-05-09

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