JP7511469B2 - 組換えエクトヌクレオチドピロホスファターゼ／ホスホジエステラーゼ（ｎｐｐ１）を使用して心血管機能を改善し、心血管疾患を処置するための方法。 - Google Patents
組換えエクトヌクレオチドピロホスファターゼ／ホスホジエステラーゼ（ｎｐｐ１）を使用して心血管機能を改善し、心血管疾患を処置するための方法。 Download PDFInfo
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C—CHEMISTRY; METALLURGY
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- C12Y—ENZYMES
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| JP2023007311A JP7598960B2 (ja) | 2017-09-27 | 2023-01-20 | 組換えエクトヌクレオチドピロホスファターゼ／ホスホジエステラーゼ（ｎｐｐ１）を使用して心血管機能を改善し、心血管疾患を処置するための方法。 |
| JP2024209675A JP2025023189A (ja) | 2017-09-27 | 2024-12-02 | 組換えエクトヌクレオチドピロホスファターゼ／ホスホジエステラーゼ（ｎｐｐ１）を使用して心血管機能を改善し、心血管疾患を処置するための方法。 |
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| PCT/US2018/052795 WO2019067502A1 (en) | 2017-09-27 | 2018-09-26 | METHODS FOR IMPROVING CARDIOVASCULAR FUNCTION AND TREATING CARDIOVASCULAR DISEASE USING RECOMBINANT ECTO-NUCLEOTIDE PYROPHOSPHATASE / PHOSPHODIESTERASE |
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| JP2023007311A Division JP7598960B2 (ja) | 2017-09-27 | 2023-01-20 | 組換えエクトヌクレオチドピロホスファターゼ／ホスホジエステラーゼ（ｎｐｐ１）を使用して心血管機能を改善し、心血管疾患を処置するための方法。 |
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| JP2020535161A JP2020535161A (ja) | 2020-12-03 |
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| JP2023007311A Active JP7598960B2 (ja) | 2017-09-27 | 2023-01-20 | 組換えエクトヌクレオチドピロホスファターゼ／ホスホジエステラーゼ（ｎｐｐ１）を使用して心血管機能を改善し、心血管疾患を処置するための方法。 |
| JP2024209675A Pending JP2025023189A (ja) | 2017-09-27 | 2024-12-02 | 組換えエクトヌクレオチドピロホスファターゼ／ホスホジエステラーゼ（ｎｐｐ１）を使用して心血管機能を改善し、心血管疾患を処置するための方法。 |
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| JP2024209675A Pending JP2025023189A (ja) | 2017-09-27 | 2024-12-02 | 組換えエクトヌクレオチドピロホスファターゼ／ホスホジエステラーゼ（ｎｐｐ１）を使用して心血管機能を改善し、心血管疾患を処置するための方法。 |
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| US11364284B2 (en) | 2016-06-16 | 2022-06-21 | Inozyme Pharma, Inc. | Methods of treating myointimal proliferation |
| EP3687565A1 (en) | 2017-09-27 | 2020-08-05 | Alexion Pharmaceuticals, Inc. | Methods of improving cardiovascular function and treating cardiovascular disease using a recombinant ectonucleotide pyrophosphatase phosphodiesterase (npp1) |
| CN116406281A (zh) * | 2020-05-27 | 2023-07-07 | 依诺兹梅制药公司 | 用于治疗外周动脉疾病的组合物和方法 |
| KR20230047334A (ko) * | 2020-05-27 | 2023-04-07 | 이노자임 파마, 인코포레이티드 | 혈관 평활근 세포 증식을 억제하기 위한 조성물 및 방법 |
| IL298853A (en) * | 2020-06-09 | 2023-02-01 | Inozyme Pharma Inc | Soluble enpp1 or enpp3 proteins and uses thereof |
| WO2023049864A1 (en) * | 2021-09-24 | 2023-03-30 | Inozyme Pharma, Inc. | Lyophilized enpp1 polypeptide formulations and uses thereof |
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| WO2016100803A2 (en) | 2014-12-19 | 2016-06-23 | Alexion Pharmaceuticals, Inc. | Methods of treating tissue calcification |
| WO2016187408A1 (en) | 2015-05-19 | 2016-11-24 | Yale University | Compositions for treating pathological calcification conditions, and methods using same |
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| US6267964B1 (en) | 1989-08-01 | 2001-07-31 | Affibody Technology Sweden Ab | Stabilized protein or peptide conjugates able to bond albumin having extended biological half-lives |
| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
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| US20020164782A1 (en) | 1999-02-10 | 2002-11-07 | Gregory Richard J. | Adenovirus vectors for gene therapy |
| JPH04292169A (ja) | 1991-03-19 | 1992-10-16 | Sekisui Chem Co Ltd | ハイブリッド型人工膵臓 |
| US5418618A (en) | 1992-03-09 | 1995-05-23 | Mita Industrial Co., Ltd. | Tone processing method for forming a halftone image |
| US5804413A (en) | 1992-07-31 | 1998-09-08 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Herpes simplex virus strains for gene transfer |
| EP0719434B1 (de) | 1993-09-15 | 1997-07-23 | Océ Printing Systems GmbH | Anordnung zur erzeugung eines rasterbildes auf einem lichtempfindlichen aufzeichunungsträger |
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| CA2280957A1 (en) | 1997-02-14 | 1998-08-20 | Leslie Orgel | Methods and compositions for delivery of therapeutic agents to bone tissue employing conjugates of negatively charged peptide oligomers with therapeutic agents |
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| JP2020535161A (ja) | 2020-12-03 |
| CA3096821A1 (en) | 2019-04-04 |
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| JP2025023189A (ja) | 2025-02-14 |
| US20250019677A1 (en) | 2025-01-16 |
| JP2023033610A (ja) | 2023-03-10 |
| WO2019067502A1 (en) | 2019-04-04 |
| JP7598960B2 (ja) | 2024-12-12 |
| US20200263153A1 (en) | 2020-08-20 |
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