JP7457454B2 - 埋め込み型管腔内プロテーゼ - Google Patents
埋め込み型管腔内プロテーゼ Download PDFInfo
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- JP7457454B2 JP7457454B2 JP2018524202A JP2018524202A JP7457454B2 JP 7457454 B2 JP7457454 B2 JP 7457454B2 JP 2018524202 A JP2018524202 A JP 2018524202A JP 2018524202 A JP2018524202 A JP 2018524202A JP 7457454 B2 JP7457454 B2 JP 7457454B2
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- 206010002329 Aneurysm Diseases 0.000 claims description 26
- 229910001000 nickel titanium Inorganic materials 0.000 claims description 6
- 239000000560 biocompatible material Substances 0.000 claims description 5
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2002/823—Stents, different from stent-grafts, adapted to cover an aneurysm
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- Health & Medical Sciences (AREA)
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- Organic Chemistry (AREA)
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Description
本発明は、埋め込み型管腔内プロテーゼに関する。より詳細には、本発明は、分枝を含む動脈瘤の治療のための管腔内プロテーゼに関する。
血管内修復は、大動脈瘤を治療するための比較的新しい低侵襲技術であることが知られている。遠く離れた場所にある血管を経由して、金属製またはプラスチック製フレーム(ステント)で支持された不透過性チューブ(グラフト)を送達する。しかしながら、それが不透過性であるために、この技術は、動脈瘤が重要な分枝(例えば、冠動脈、上大動脈分枝、腎および中副腎動脈、内蔵動脈および内腸骨動脈)を含む動脈瘤修復には適用できない。さもなければ、分枝の閉塞を伴う重篤な合併症を引き起こす。
本発明の第1の目的は、分枝を含む動脈瘤を治療するために、血管内アプローチによって埋め込むことができる機器を提供することである。
本発明の他の特殊性および利点は、以下発展され、添付図面を参照する。
下記では、用語「埋め込み型」は、身体血管内のある箇所に位置決めされる医療機器の能力を指す。埋め込み型医療機器は、医療的介入の際に身体血管内に一時的に配置されるように(例えば、数秒、数分、数時間)、または身体血管内に永久的に留まるように、構成され得る。
SCR=Sw/St
によって定義される。ここで、「Sw」は、管腔内プロテーゼ1に構成されるワイヤ21によって被覆される実際の表面であり、および「St」は、壁に対して垂直に観察するときの、管腔内プロテーゼ1の壁の全表面積である。
Claims (9)
- 送達形態における半径方向に圧縮した状態から、半径方向に拡張した状態まで拡張できる、軸に沿って延在する少なくとも1つの自己拡張型編組フレームワーク(20)から実質的になる多層構成を有する、分枝を含む動脈瘤の治療に使用される埋め込み型管腔内プロテーゼ(1)であって;前記自己拡張型編組フレームワーク(20)は、単一で所与のワイヤ直径(Φ21)を有する、多くても196本のワイヤ(21)で形成され;この自己拡張型編組フレームワーク(20)は、いずれの不透過性カバー層も欠いており、生体適合性材料で作製されたワイヤ(21)の複数の層を含み;および前記管腔内プロテーゼ(1)の壁を形成し;各層はメッシュを形成し;前記メッシュは、前記層の複数のワイヤ(21)で格子を形成し;前記メッシュはからみ合わせられており、前記層が編組時に区別できず、第1の層のワイヤが第2の層および/または他の層のワイヤとからみ合わせられており、各ワイヤは、隣接する層のうちの少なくとも1つの層の前記メッシュに組み込まれており;前記自己拡張型編組フレームワーク(20)は、円形横断面および一定直径のシリンダー形のルーメンを含む、埋め込み型管腔内プロテーゼ(1)において;半径方向に拡張した状態において、半径方向に拡張した状態における前記埋め込み型管腔内プロテーゼ(1)の壁の厚さ(T1)対ワイヤ(21)の前記直径(Φ21)の比(T1/Φ21)は、3.0超であり;および前記編組フレームワーク(20)の表面被覆率(SCR)は、少なくとも35%および多くても50%であり、各ワイヤ(21)の前記直径が少なくとも120μmであり、複数層構成のワイヤは、隣接する平行するワイヤ間において一定の距離を保つようにシフトし、前記SCRが湾曲状態および直線構成において維持されることを特徴とする、埋め込み型管腔内プロテーゼ(1)。
- 前記比(T1/Φ21)が少なくとも3.5である、請求項1に記載の埋め込み型管腔内プロテーゼ(1)。
- 前記比(T1/Φ21)が少なくとも4.0である、請求項1に記載の埋め込み型管腔内プロテーゼ(1)。
- 前記自己拡張型編組フレームワーク(20)が、少なくとも90本のワイヤおよび多くても130本のワイヤを含む、請求項1~3のいずれか1項に記載の埋め込み型管腔内プロテーゼ(1)。
- 前記ワイヤ(21)の前記直径が少なくとも150μmである、請求項1に記載の埋め込み型管腔内プロテーゼ(1)。
- 前記ワイヤ(21)の前記直径が少なくとも180μmである、請求項5に記載の埋め込み型管腔内プロテーゼ(1)。
- 前記ワイヤ(21)の前記直径が少なくとも200μmおよび多くても220μmである、請求項6に記載の埋め込み型管腔内プロテーゼ(1)。
- 前記生体適合性材料が、チタン、ニッケル-チタン合金、任意のタイプのステンレス鋼、およびコバルト-クロム-ニッケル合金からなる群から選択される金属基材である、請求項1~7のいずれか1項に記載の埋め込み型管腔内プロテーゼ。
- 前記生体適合性材料が、ニチノール、Nitinol-DFT(登録商標)-Platinum、およびPhynox(登録商標)からなる群から選択される金属基材である、請求項1~7のいずれか1項に記載の埋め込み型管腔内プロテーゼ。
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Application Number | Priority Date | Filing Date | Title |
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JP2021209996A JP2022031413A (ja) | 2015-11-13 | 2021-12-23 | 埋め込み型管腔内プロテーゼ |
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---|---|---|---|
IN3716DE2015 | 2015-11-13 | ||
IN3716/DEL/2015 | 2015-11-13 | ||
PCT/EP2016/077363 WO2017081213A1 (en) | 2015-11-13 | 2016-11-10 | Implantable endoluminal prosthesis |
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JP2021209996A Division JP2022031413A (ja) | 2015-11-13 | 2021-12-23 | 埋め込み型管腔内プロテーゼ |
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JP2018535009A JP2018535009A (ja) | 2018-11-29 |
JPWO2017081213A5 JPWO2017081213A5 (ja) | 2023-04-20 |
JP7457454B2 true JP7457454B2 (ja) | 2024-03-28 |
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JP2018524202A Active JP7457454B2 (ja) | 2015-11-13 | 2016-11-10 | 埋め込み型管腔内プロテーゼ |
JP2021209996A Pending JP2022031413A (ja) | 2015-11-13 | 2021-12-23 | 埋め込み型管腔内プロテーゼ |
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JP2021209996A Pending JP2022031413A (ja) | 2015-11-13 | 2021-12-23 | 埋め込み型管腔内プロテーゼ |
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US (2) | US11540930B2 (ja) |
EP (1) | EP3373865A1 (ja) |
JP (2) | JP7457454B2 (ja) |
KR (1) | KR20180082483A (ja) |
CN (3) | CN115381516A (ja) |
AU (2) | AU2016352832A1 (ja) |
BR (1) | BR112018009523A2 (ja) |
CA (1) | CA3004957A1 (ja) |
IL (1) | IL259264A (ja) |
MA (1) | MA43223A (ja) |
RU (1) | RU2018120328A (ja) |
WO (1) | WO2017081213A1 (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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US10888414B2 (en) | 2019-03-20 | 2021-01-12 | inQB8 Medical Technologies, LLC | Aortic dissection implant |
CN114028049B (zh) * | 2021-12-21 | 2022-08-12 | 南京纽诺英特医疗科技有限公司 | 颅内支撑支架 |
EP4311527A1 (en) | 2022-07-29 | 2024-01-31 | Intressa Vascular S.A. | Implantable 3d braided endovascular prosthesis for remodeling of dissected aorta |
Citations (2)
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JP2008200499A (ja) | 2007-02-20 | 2008-09-04 | Cardiatis Sa | 過形成プラーク予防用ステント |
JP2015513931A (ja) | 2012-03-16 | 2015-05-18 | マイクロベンション インコーポレイテッド | ステントおよびステント送達装置 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
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BE1013757A6 (fr) * | 2000-12-12 | 2002-07-02 | Frid Noureddine | Endoprothese luminale modulable. |
US6650140B2 (en) | 2001-03-19 | 2003-11-18 | Altera Corporation | Programmable logic device with high speed serial interface circuitry |
EP1374799A1 (en) * | 2002-06-18 | 2004-01-02 | F.R.I.D. R&D Benelux Sprl | Hemodynamic luminal endoprosthesis |
EP1769774A1 (fr) * | 2005-10-03 | 2007-04-04 | Noureddine Frid | Endoprothèse radio-opaque |
WO2009105176A2 (en) * | 2008-02-19 | 2009-08-27 | William Cook Europe Aps | Coated endoluminal implant |
WO2012084007A1 (en) * | 2010-12-20 | 2012-06-28 | Graftcraft I Göteborg Ab | Removable stent and method of production |
US10219924B2 (en) * | 2012-12-26 | 2019-03-05 | Stryker Corporation | Multilayer stent |
US20140277397A1 (en) * | 2013-03-12 | 2014-09-18 | DePuy Synthes Products, LLC | Variable porosity intravascular implant and manufacturing method |
EP2915509A1 (en) * | 2014-03-05 | 2015-09-09 | Cardiatis S.A. | Stent assembly for thoracoabdominal bifurcated aneurysm repair |
CN104161604B (zh) * | 2014-08-06 | 2016-08-24 | 中国人民解放军第二军医大学 | 一种分体式多层动脉裸支架 |
EP2987463A1 (en) * | 2014-08-21 | 2016-02-24 | Noureddine Frid | 3d filter for prevention of stroke |
CN204542477U (zh) * | 2015-02-10 | 2015-08-12 | 东莞颠覆产品设计有限公司 | 一种多层可扩张血管支架 |
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- 2016-11-10 AU AU2016352832A patent/AU2016352832A1/en not_active Abandoned
- 2016-11-10 JP JP2018524202A patent/JP7457454B2/ja active Active
- 2016-11-10 EP EP16805311.4A patent/EP3373865A1/en not_active Withdrawn
- 2016-11-10 CN CN202210706215.XA patent/CN115381516A/zh active Pending
- 2016-11-10 KR KR1020187015395A patent/KR20180082483A/ko not_active Application Discontinuation
- 2016-11-10 CA CA3004957A patent/CA3004957A1/en not_active Abandoned
- 2016-11-10 RU RU2018120328A patent/RU2018120328A/ru not_active Application Discontinuation
- 2016-11-10 WO PCT/EP2016/077363 patent/WO2017081213A1/en active Application Filing
- 2016-11-10 CN CN201680066064.9A patent/CN108289746A/zh active Pending
- 2016-11-10 CN CN202310769281.6A patent/CN116747059A/zh active Pending
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2021
- 2021-09-28 AU AU2021240135A patent/AU2021240135B2/en active Active
- 2021-12-23 JP JP2021209996A patent/JP2022031413A/ja active Pending
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Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2008200499A (ja) | 2007-02-20 | 2008-09-04 | Cardiatis Sa | 過形成プラーク予防用ステント |
JP2015513931A (ja) | 2012-03-16 | 2015-05-18 | マイクロベンション インコーポレイテッド | ステントおよびステント送達装置 |
Also Published As
Publication number | Publication date |
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US11540930B2 (en) | 2023-01-03 |
RU2018120328A (ru) | 2019-12-13 |
AU2016352832A1 (en) | 2018-05-31 |
IL259264A (en) | 2018-07-31 |
BR112018009523A2 (pt) | 2018-11-06 |
AU2021240135B2 (en) | 2023-08-31 |
MA43223A (fr) | 2018-09-19 |
WO2017081213A1 (en) | 2017-05-18 |
US20230277344A1 (en) | 2023-09-07 |
AU2021240135A1 (en) | 2021-10-28 |
KR20180082483A (ko) | 2018-07-18 |
CA3004957A1 (en) | 2017-05-18 |
CN115381516A (zh) | 2022-11-25 |
US20180325708A1 (en) | 2018-11-15 |
CN108289746A (zh) | 2018-07-17 |
JP2022031413A (ja) | 2022-02-18 |
CN116747059A (zh) | 2023-09-15 |
JP2018535009A (ja) | 2018-11-29 |
EP3373865A1 (en) | 2018-09-19 |
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