JP7431155B2 - テトラヒドロナフチルウレア誘導体の製造方法 - Google Patents
テトラヒドロナフチルウレア誘導体の製造方法 Download PDFInfo
- Publication number
- JP7431155B2 JP7431155B2 JP2020511064A JP2020511064A JP7431155B2 JP 7431155 B2 JP7431155 B2 JP 7431155B2 JP 2020511064 A JP2020511064 A JP 2020511064A JP 2020511064 A JP2020511064 A JP 2020511064A JP 7431155 B2 JP7431155 B2 JP 7431155B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- formula
- mixed solution
- compound represented
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/04—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/44—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B61/00—Other general methods
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epoxy Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018068290 | 2018-03-30 | ||
| JP2018068290 | 2018-03-30 | ||
| PCT/JP2019/013916 WO2019189717A1 (ja) | 2018-03-30 | 2019-03-29 | テトラヒドロナフチルウレア誘導体の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2019189717A1 JPWO2019189717A1 (ja) | 2021-05-13 |
| JPWO2019189717A5 JPWO2019189717A5 (https=) | 2022-03-23 |
| JP7431155B2 true JP7431155B2 (ja) | 2024-02-14 |
Family
ID=68059235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020511064A Active JP7431155B2 (ja) | 2018-03-30 | 2019-03-29 | テトラヒドロナフチルウレア誘導体の製造方法 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP7431155B2 (https=) |
| WO (1) | WO2019189717A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2024111552A1 (https=) | 2022-11-21 | 2024-05-30 | ||
| CN116223657B (zh) * | 2022-12-30 | 2023-09-15 | 上海药坦药物研究开发有限公司 | 一种蔗糖铁制品中有机酸的检测方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008255086A (ja) | 2007-03-10 | 2008-10-23 | Nissan Chem Ind Ltd | 光学活性エポキシ化合物の製造方法 |
| JP2015537001A (ja) | 2012-11-13 | 2015-12-24 | アレイ バイオファーマ、インコーポレイテッド | 疼痛の治療に有用な二環式尿素、チオ尿素、グアニジン、およびシアノグアニジン化合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06247993A (ja) * | 1992-12-28 | 1994-09-06 | Mitsui Petrochem Ind Ltd | 光学活性エポキシドの製造方法および新規なマンガン化合物 |
| ES2992887T3 (en) * | 2017-04-27 | 2024-12-19 | Mochida Pharm Co Ltd | Novel tetrahydronaphthyl urea derivatives as inhibitors of tropomyosin receptor kinase a for the treatment of pain |
-
2019
- 2019-03-29 WO PCT/JP2019/013916 patent/WO2019189717A1/ja not_active Ceased
- 2019-03-29 JP JP2020511064A patent/JP7431155B2/ja active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008255086A (ja) | 2007-03-10 | 2008-10-23 | Nissan Chem Ind Ltd | 光学活性エポキシ化合物の製造方法 |
| JP2015537001A (ja) | 2012-11-13 | 2015-12-24 | アレイ バイオファーマ、インコーポレイテッド | 疼痛の治療に有用な二環式尿素、チオ尿素、グアニジン、およびシアノグアニジン化合物 |
Non-Patent Citations (1)
| Title |
|---|
| KONDO, S. et al.，Angewandte Chemie International Edition，2008年，Vol. 47，pp. 10195-10198 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2019189717A1 (ja) | 2021-05-13 |
| WO2019189717A1 (ja) | 2019-10-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022518591A (ja) | 複素環式化合物であるベンゾピリドンおよびその使用 | |
| AU652996B2 (en) | Acridine derivatives | |
| KR100634039B1 (ko) | 신규한 페닐피페라진 | |
| JP5208239B2 (ja) | アルキンカップリングによる抗がん活性三環式化合物の新規製法 | |
| JP7503850B2 (ja) | シャペロン介在性オートファジー調節剤として有用なベンゾオキサゾールおよび関連化合物 | |
| US20070299091A1 (en) | Azaindole Carboxamides | |
| FR2917412A1 (fr) | Derives de 7-alkynyl, 1,8-naphthyridones, leur preparation et leur application en therapeutique | |
| JP7431155B2 (ja) | テトラヒドロナフチルウレア誘導体の製造方法 | |
| JP2016515101A (ja) | 新規スルホンアミドｔｒｐａ１受容体アンタゴニスト | |
| JPH10511084A (ja) | ポリアリールカルバモイルアザ及びカルバモイルアルカン二酸 | |
| JPH04500362A (ja) | 新規な８―置換―２―アミノテトラリン類 | |
| JP2013505261A (ja) | ４，５，６，７−テトラクロロ−３’，６’−ジヒドロキシ−２’，４’，５’，７’−テトラヨード−３ｈ−スピロ［イソベンゾフラン−１，９’−キサンテン］−３−オン（ローズベンガル）及び関連するキサンテンを合成するプロセス | |
| JP5441060B2 (ja) | 創薬のためのｐｅｔスクリーニング用分子プローブを製造するためのキット | |
| JPH0686431B2 (ja) | 喘息治療用の置換テトラリン、クロマン及び関連化合物 | |
| Taniguchi et al. | Solvent control of optical resolution of 2-amino-1-phenylethanol using dehydroabietic acid | |
| JP2023544790A (ja) | 縮合環ジイミド誘導体、その製造方法と使用 | |
| CN113816855A (zh) | 合成手性烯丙基羧酸酯的方法 | |
| CN105085396A (zh) | 用于制备贝达喹啉的中间体及其制备方法和应用 | |
| JP4762551B2 (ja) | インデノンカルボン酸誘導体ならびに糖尿病および脂質代謝異常を治療および予防するためのそれらの使用 | |
| JP7134982B2 (ja) | ジアルキルジヒドロナフタレン誘導体の製造方法 | |
| WO2015012271A1 (ja) | 複素環化合物の製造方法 | |
| JP2014527977A (ja) | 新規合成方法 | |
| JP2769058B2 (ja) | シクロプロパン誘導体の製法 | |
| JP4130822B2 (ja) | スクラレオリドの前駆体の光学分割法 | |
| JP2001512491A (ja) | １−（イソキノリン−１−イル）−４−（１−フェニメチル）ピペラジン；ドーパミン受容体サブタイプ特異的リガンド |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20220311 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20220311 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20230501 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20230612 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20230925 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20231019 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20240109 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20240201 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 7431155 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |