JP7424728B2 - Rna干渉のための長鎖の二本鎖rna - Google Patents
Rna干渉のための長鎖の二本鎖rna Download PDFInfo
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- JP7424728B2 JP7424728B2 JP2019565074A JP2019565074A JP7424728B2 JP 7424728 B2 JP7424728 B2 JP 7424728B2 JP 2019565074 A JP2019565074 A JP 2019565074A JP 2019565074 A JP2019565074 A JP 2019565074A JP 7424728 B2 JP7424728 B2 JP 7424728B2
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| EP3377630A4 (en) | 2015-11-16 | 2020-01-01 | Olix Pharmaceuticals, Inc. | Treatment of age-related macular degeneration using rna complexes that target myd88 or tlr3 |
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| KR101916652B1 (ko) | 2016-06-29 | 2018-11-08 | 올릭스 주식회사 | 작은 간섭 rna의 rna 간섭효과 증진용 화합물 및 이의 용도 |
| US11591600B2 (en) | 2017-02-10 | 2023-02-28 | OliX Pharmaceuticals. Inc. | Long double-stranded RNA for RNA interference |
| WO2023043239A1 (ko) * | 2021-09-15 | 2023-03-23 | 올릭스 주식회사 | 선천성 면역 반응 유도 효과를 갖는 이중가닥 rna 및 이의 용도 |
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| US20140288148A1 (en) | 2002-02-20 | 2014-09-25 | Sirna Therapeutics Inc | RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) |
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| US20050282188A1 (en) | 2001-05-18 | 2005-12-22 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) |
| US20080188430A1 (en) | 2001-05-18 | 2008-08-07 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA) |
| ES2566561T3 (es) * | 2001-07-12 | 2016-04-13 | University Of Massachusetts | Producción in vivo de ARN pequeños de interferencia que median el silenciamiento génico |
| JP2005506087A (ja) | 2001-10-26 | 2005-03-03 | リボファーマ アーゲー | プラス鎖rnaウイルスによる感染症を処置するための2本鎖リボ核酸の使用 |
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| ES2280826T5 (es) | 2002-08-05 | 2017-08-03 | Silence Therapeutics Gmbh | Nuevas formas adicionales de moléculas de ARN de interferencia |
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| WO2005062937A2 (en) | 2003-12-22 | 2005-07-14 | University Of Massachusetts | Methods and compositions for enhancing the efficacy and specificity of single and double blunt-ended sirna |
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| WO2005079533A2 (en) | 2004-02-17 | 2005-09-01 | University Of Massachusetts | Methods and compositions for mediating gene silencing |
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| EP1765847A4 (en) | 2004-05-27 | 2010-10-20 | Alnylam Pharmaceuticals Inc | NUCLEASERESISTENT DOUBLE-STRANDED RIBONUCLEIC ACID |
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| US11591600B2 (en) | 2023-02-28 |
| WO2018146557A2 (en) | 2018-08-16 |
| US20210285001A1 (en) | 2021-09-16 |
| WO2018146557A3 (en) | 2018-10-25 |
| CN110770343A (zh) | 2020-02-07 |
| EP3580339A2 (en) | 2019-12-18 |
| JP2020508078A (ja) | 2020-03-19 |
| KR20190108167A (ko) | 2019-09-23 |
| EP3580339A4 (en) | 2020-12-23 |
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