CN110770343A - 用于rna干扰的长双链rna - Google Patents

用于rna干扰的长双链rna Download PDF

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CN110770343A
CN110770343A CN201880024222.3A CN201880024222A CN110770343A CN 110770343 A CN110770343 A CN 110770343A CN 201880024222 A CN201880024222 A CN 201880024222A CN 110770343 A CN110770343 A CN 110770343A
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ldrna
mrna
cells
composition
complementary
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李东起
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Olix Pharmaceuticals Inc
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Sungkyunkwan University School Industry Cooperation
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CN201880024222.3A 2017-02-10 2018-02-12 用于rna干扰的长双链rna Pending CN110770343A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762457282P 2017-02-10 2017-02-10
US62/457,282 2017-02-10
PCT/IB2018/000330 WO2018146557A2 (en) 2017-02-10 2018-02-12 Long double-stranded rna for rna interference

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CN110770343A true CN110770343A (zh) 2020-02-07

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US (1) US11591600B2 (enExample)
EP (1) EP3580339A4 (enExample)
JP (1) JP7424728B2 (enExample)
KR (1) KR20190108167A (enExample)
CN (1) CN110770343A (enExample)
WO (1) WO2018146557A2 (enExample)

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CN103328633B (zh) 2010-10-22 2018-07-10 成均馆大学校产学协力团 诱导rna干扰的核酸分子及其用途
CN108148838B (zh) 2012-05-22 2026-07-31 奥利克斯医药有限公司 具有细胞内穿透能力的诱导rna干扰的核酸分子及用途
JP7027311B2 (ja) 2015-11-16 2022-03-01 オリックス ファーマシューティカルズ，インコーポレーテッド ＭｙＤ８８又はＴＬＲ３を標的とするＲＮＡ複合体を使用した加齢黄斑変性の治療
KR102825945B1 (ko) 2016-02-02 2025-06-30 올릭스 주식회사 Angpt2 및 pdgfb를 표적화하는 rna 복합체를 사용하는 혈관신생 관련 질환의 치료
WO2017134525A1 (en) 2016-02-02 2017-08-10 Olix Pharmaceuticals, Inc. TREATMENT OF ATOPIC DERMATITIS AND ASTHMA USING RNA COMPLEXES THAT TARGET lL4Rα, TRPA1, OR F2RL1
JP7049262B2 (ja) 2016-04-11 2022-04-06 オリックス ファーマシューティカルズ，インコーポレーテッド 結合組織成長因子を標的とするｒｎａ複合体を用いた特発性肺胞線維症の治療
KR101916652B1 (ko) 2016-06-29 2018-11-08 올릭스 주식회사 작은 간섭 rna의 rna 간섭효과 증진용 화합물 및 이의 용도
WO2018146557A2 (en) 2017-02-10 2018-08-16 Dong Ki Lee Long double-stranded rna for rna interference
KR102421750B1 (ko) 2020-05-26 2022-07-19 올릭스 주식회사 MyD88을 표적으로 하는 RNAi 제제 및 이의 용도
WO2023043239A1 (ko) * 2021-09-15 2023-03-23 올릭스 주식회사 선천성 면역 반응 유도 효과를 갖는 이중가닥 rna 및 이의 용도
WO2024186166A1 (ko) * 2023-03-08 2024-09-12 올릭스 주식회사 선천성 면역 반응 유도 효과를 갖는 이중가닥 rna 및 이의 용도
WO2026054553A1 (ko) * 2024-09-06 2026-03-12 올릭스 주식회사 선천성 면역 반응 기반 항암 요법을 위한 이중 가닥 rna 및 이의 용도

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