JP7418354B2 - シクロペンタン化合物 - Google Patents

シクロペンタン化合物 Download PDF

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JP7418354B2
JP7418354B2 JP2020563695A JP2020563695A JP7418354B2 JP 7418354 B2 JP7418354 B2 JP 7418354B2 JP 2020563695 A JP2020563695 A JP 2020563695A JP 2020563695 A JP2020563695 A JP 2020563695A JP 7418354 B2 JP7418354 B2 JP 7418354B2
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fluorophenyl
cyclopentyl
compound
piperidyl
amino
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Japanese (ja)
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JP2021523178A5 (https=
JP2021523178A (ja
JPWO2019215268A5 (https=
Inventor
チャン，シャオリン
パン，ウェイタオ
ニキティディス，グリゴリアス
リンハーゲン，ジェニー・スザンナ・マリカ
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ディザル（ジァンスー）ファーマシューティカル・カンパニー・リミテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2020563695A 2018-05-11 2019-05-09 シクロペンタン化合物 Active JP7418354B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2018/086503 2018-05-11
CN2018086503 2018-05-11
PCT/EP2019/061888 WO2019215268A1 (en) 2018-05-11 2019-05-09 Cyclopentane compounds

Publications (4)

Publication Number Publication Date
JP2021523178A JP2021523178A (ja) 2021-09-02
JP2021523178A5 JP2021523178A5 (https=) 2022-05-13
JPWO2019215268A5 JPWO2019215268A5 (https=) 2022-05-13
JP7418354B2 true JP7418354B2 (ja) 2024-01-19

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ID=66542241

Family Applications (1)

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JP2020563695A Active JP7418354B2 (ja) 2018-05-11 2019-05-09 シクロペンタン化合物

Country Status (16)

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US (2) US11274091B2 (https=)
EP (1) EP3790870B1 (https=)
JP (1) JP7418354B2 (https=)
KR (1) KR102806779B1 (https=)
CN (1) CN112424182B (https=)
AR (1) AR115382A1 (https=)
AU (1) AU2019266525B2 (https=)
BR (1) BR112020023065A2 (https=)
CA (1) CA3099507A1 (https=)
DK (1) DK3790870T3 (https=)
ES (1) ES2944735T3 (https=)
MX (1) MX2020012065A (https=)
PT (1) PT3790870T (https=)
TW (1) TWI830733B (https=)
UY (1) UY38229A (https=)
WO (1) WO2019215268A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI830733B (zh) * 2018-05-11 2024-02-01 中國大陸商迪哲（江蘇）醫藥有限公司 環戊烷化合物
JP7594274B2 (ja) 2019-10-24 2024-12-04 国立大学法人大阪大学 難聴の予防および／または治療用医薬組成物
WO2025008249A1 (en) 2023-07-06 2025-01-09 Basf Se Triazole compounds for the control of invertebrate pests

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007532596A (ja) 2004-04-14 2007-11-15 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｍｃｈ拮抗効果を有する新規アルキン化合物及び前記化合物を含有する薬物
JP2013521250A (ja) 2010-03-01 2013-06-10 サノフイ アミノインダンの誘導体、これらの調製および治療におけるこれらの適用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006001958A2 (en) * 2004-05-21 2006-01-05 Merck & Co., Inc. Amino cyclopentyl heterocyclic and carbocyclic modulators of chemokine receptor activity
EP2049500B1 (en) * 2006-07-06 2011-09-07 Array Biopharma, Inc. Cyclopenta [d] pyrimidines as akt protein kinase inhibitors
CN102015708B (zh) * 2008-01-09 2014-03-26 阵列生物制药公司 作为akt蛋白激酶抑制剂的嘧啶基环戊烷
PT2370442E (pt) * 2008-11-26 2013-06-27 Pfizer 3-aminociclopentanocarboxamidas como moduladores de receptor de quimiocina
US7893099B2 (en) * 2009-06-11 2011-02-22 Hoffman-La Roche Inc. Cyclopentane derivatives
CN105308040B (zh) * 2013-06-21 2019-06-04 默克专利股份公司 1,3-二氨基环戊烷甲酰胺衍生物
SG11201600726QA (en) * 2013-07-29 2016-03-30 Merck Patent Gmbh 1,3-disubstituted cyclopentane derivatives
TWI830733B (zh) * 2018-05-11 2024-02-01 中國大陸商迪哲（江蘇）醫藥有限公司 環戊烷化合物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007532596A (ja) 2004-04-14 2007-11-15 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｍｃｈ拮抗効果を有する新規アルキン化合物及び前記化合物を含有する薬物
JP2013521250A (ja) 2010-03-01 2013-06-10 サノフイ アミノインダンの誘導体、これらの調製および治療におけるこれらの適用

Also Published As

Publication number Publication date
UY38229A (es) 2019-11-29
AR115382A1 (es) 2021-01-13
JP2021523178A (ja) 2021-09-02
US12378218B2 (en) 2025-08-05
AU2019266525A1 (en) 2020-11-26
KR102806779B1 (ko) 2025-05-12
EP3790870B1 (en) 2023-04-19
EP3790870A1 (en) 2021-03-17
BR112020023065A2 (pt) 2021-02-02
KR20210018287A (ko) 2021-02-17
PT3790870T (pt) 2023-05-05
US20210070733A1 (en) 2021-03-11
CN112424182B (zh) 2023-05-23
AU2019266525B2 (en) 2024-06-13
CA3099507A1 (en) 2019-11-14
US20220194922A1 (en) 2022-06-23
MX2020012065A (es) 2021-02-26
TW202016087A (zh) 2020-05-01
US11274091B2 (en) 2022-03-15
ES2944735T3 (es) 2023-06-23
DK3790870T3 (da) 2023-05-08
CN112424182A (zh) 2021-02-26
WO2019215268A1 (en) 2019-11-14
TWI830733B (zh) 2024-02-01

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