AR115382A1 - Compuestos de ciclopentano - Google Patents
Compuestos de ciclopentanoInfo
- Publication number
- AR115382A1 AR115382A1 ARP190101251A ARP190101251A AR115382A1 AR 115382 A1 AR115382 A1 AR 115382A1 AR P190101251 A ARP190101251 A AR P190101251A AR P190101251 A ARP190101251 A AR P190101251A AR 115382 A1 AR115382 A1 AR 115382A1
- Authority
- AR
- Argentina
- Prior art keywords
- independently selected
- alkyl
- optionally substituted
- formula
- membered aromatic
- Prior art date
Links
- RGSFGYAAUTVSQA-UHFFFAOYSA-N Cyclopentane Chemical class C1CCCC1 RGSFGYAAUTVSQA-UHFFFAOYSA-N 0.000 title 1
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001511 cyclopentyl group Chemical class [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- -1 methoxy, hydroxy Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 125000003373 pyrazinyl group Chemical group 0.000 abstract 1
- 125000005495 pyridazyl group Chemical group 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2018086503 | 2018-05-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR115382A1 true AR115382A1 (es) | 2021-01-13 |
Family
ID=66542241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP190101251A AR115382A1 (es) | 2018-05-11 | 2019-05-10 | Compuestos de ciclopentano |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11274091B2 (https=) |
| EP (1) | EP3790870B1 (https=) |
| JP (1) | JP7418354B2 (https=) |
| KR (1) | KR102806779B1 (https=) |
| CN (1) | CN112424182B (https=) |
| AR (1) | AR115382A1 (https=) |
| AU (1) | AU2019266525B2 (https=) |
| BR (1) | BR112020023065A2 (https=) |
| CA (1) | CA3099507A1 (https=) |
| DK (1) | DK3790870T3 (https=) |
| ES (1) | ES2944735T3 (https=) |
| MX (1) | MX2020012065A (https=) |
| PT (1) | PT3790870T (https=) |
| TW (1) | TWI830733B (https=) |
| UY (1) | UY38229A (https=) |
| WO (1) | WO2019215268A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI830733B (zh) * | 2018-05-11 | 2024-02-01 | 中國大陸商迪哲（江蘇）醫藥有限公司 | 環戊烷化合物 |
| JP7594274B2 (ja) | 2019-10-24 | 2024-12-04 | 国立大学法人大阪大学 | 難聴の予防および／または治療用医薬組成物 |
| WO2025008249A1 (en) | 2023-07-06 | 2025-01-09 | Basf Se | Triazole compounds for the control of invertebrate pests |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004017930A1 (de) | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
| WO2006001958A2 (en) * | 2004-05-21 | 2006-01-05 | Merck & Co., Inc. | Amino cyclopentyl heterocyclic and carbocyclic modulators of chemokine receptor activity |
| EP2049500B1 (en) * | 2006-07-06 | 2011-09-07 | Array Biopharma, Inc. | Cyclopenta [d] pyrimidines as akt protein kinase inhibitors |
| CN102015708B (zh) * | 2008-01-09 | 2014-03-26 | 阵列生物制药公司 | 作为akt蛋白激酶抑制剂的嘧啶基环戊烷 |
| PT2370442E (pt) * | 2008-11-26 | 2013-06-27 | Pfizer | 3-aminociclopentanocarboxamidas como moduladores de receptor de quimiocina |
| US7893099B2 (en) * | 2009-06-11 | 2011-02-22 | Hoffman-La Roche Inc. | Cyclopentane derivatives |
| EP2368876A1 (en) | 2010-03-01 | 2011-09-28 | Sanofi | Derivatives of aminoindanes, their preparation and their application in therapeutics |
| CN105308040B (zh) * | 2013-06-21 | 2019-06-04 | 默克专利股份公司 | 1,3-二氨基环戊烷甲酰胺衍生物 |
| SG11201600726QA (en) * | 2013-07-29 | 2016-03-30 | Merck Patent Gmbh | 1,3-disubstituted cyclopentane derivatives |
| TWI830733B (zh) * | 2018-05-11 | 2024-02-01 | 中國大陸商迪哲（江蘇）醫藥有限公司 | 環戊烷化合物 |
-
2019
- 2019-05-06 TW TW108115491A patent/TWI830733B/zh active
- 2019-05-09 WO PCT/EP2019/061888 patent/WO2019215268A1/en not_active Ceased
- 2019-05-09 MX MX2020012065A patent/MX2020012065A/es unknown
- 2019-05-09 PT PT197241524T patent/PT3790870T/pt unknown
- 2019-05-09 CA CA3099507A patent/CA3099507A1/en active Pending
- 2019-05-09 KR KR1020207035633A patent/KR102806779B1/ko active Active
- 2019-05-09 CN CN201980046444.XA patent/CN112424182B/zh active Active
- 2019-05-09 ES ES19724152T patent/ES2944735T3/es active Active
- 2019-05-09 JP JP2020563695A patent/JP7418354B2/ja active Active
- 2019-05-09 AU AU2019266525A patent/AU2019266525B2/en active Active
- 2019-05-09 DK DK19724152.4T patent/DK3790870T3/da active
- 2019-05-09 EP EP19724152.4A patent/EP3790870B1/en active Active
- 2019-05-09 BR BR112020023065-0A patent/BR112020023065A2/pt unknown
- 2019-05-10 AR ARP190101251A patent/AR115382A1/es unknown
- 2019-05-10 UY UY0001038229A patent/UY38229A/es not_active Application Discontinuation
-
2020
- 2020-11-11 US US17/095,725 patent/US11274091B2/en active Active
-
2021
- 2021-12-27 US US17/562,022 patent/US12378218B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| UY38229A (es) | 2019-11-29 |
| JP2021523178A (ja) | 2021-09-02 |
| US12378218B2 (en) | 2025-08-05 |
| AU2019266525A1 (en) | 2020-11-26 |
| KR102806779B1 (ko) | 2025-05-12 |
| EP3790870B1 (en) | 2023-04-19 |
| EP3790870A1 (en) | 2021-03-17 |
| BR112020023065A2 (pt) | 2021-02-02 |
| KR20210018287A (ko) | 2021-02-17 |
| PT3790870T (pt) | 2023-05-05 |
| US20210070733A1 (en) | 2021-03-11 |
| CN112424182B (zh) | 2023-05-23 |
| AU2019266525B2 (en) | 2024-06-13 |
| CA3099507A1 (en) | 2019-11-14 |
| US20220194922A1 (en) | 2022-06-23 |
| JP7418354B2 (ja) | 2024-01-19 |
| MX2020012065A (es) | 2021-02-26 |
| TW202016087A (zh) | 2020-05-01 |
| US11274091B2 (en) | 2022-03-15 |
| ES2944735T3 (es) | 2023-06-23 |
| DK3790870T3 (da) | 2023-05-08 |
| CN112424182A (zh) | 2021-02-26 |
| WO2019215268A1 (en) | 2019-11-14 |
| TWI830733B (zh) | 2024-02-01 |
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