JP7399168B2 - 顕微鏡画像化用の試料チャンバの作動方法、装置、及び試料チャンバ - Google Patents

顕微鏡画像化用の試料チャンバの作動方法、装置、及び試料チャンバ Download PDF

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JP7399168B2
JP7399168B2 JP2021535872A JP2021535872A JP7399168B2 JP 7399168 B2 JP7399168 B2 JP 7399168B2 JP 2021535872 A JP2021535872 A JP 2021535872A JP 2021535872 A JP2021535872 A JP 2021535872A JP 7399168 B2 JP7399168 B2 JP 7399168B2
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sample
sample chamber
illumination
wall
chamber
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JP2022521567A (ja
JP2022521567A5 (enExample
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カルクブレンナー,トマス
ヴォレスチェンスキー,ラルフ
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Carl Zeiss Microscopy GmbH
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Carl Zeiss Microscopy GmbH
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    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0032Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/34Microscope slides, e.g. mounting specimens on microscope slides
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036Scanning details, e.g. scanning stages
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052Optical details of the image generation
    • G02B21/0076Optical details of the image generation arrangements using fluorescence or luminescence
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/06Means for illuminating specimens
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/24Base structure
    • G02B21/26Stages; Adjusting means therefor
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/36Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365Control or image processing arrangements for digital or video microscopes
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/36Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365Control or image processing arrangements for digital or video microscopes
    • G02B21/367Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2021535872A 2018-12-19 2019-12-02 顕微鏡画像化用の試料チャンバの作動方法、装置、及び試料チャンバ Active JP7399168B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102018222271.1 2018-12-19
DE102018222271.1A DE102018222271A1 (de) 2018-12-19 2018-12-19 Verfahren zum Betrieb einer Probenkammer für eine mikroskopische Bildgebung sowie Vorrichtung und Probenkammer
PCT/EP2019/083222 WO2020126419A1 (de) 2018-12-19 2019-12-02 Verfahren zum betrieb einer probenkammer für eine mikroskopische bildgebung sowie vorrichtung und probenkammer

Publications (3)

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JP2022521567A JP2022521567A (ja) 2022-04-11
JP2022521567A5 JP2022521567A5 (enExample) 2022-10-20
JP7399168B2 true JP7399168B2 (ja) 2023-12-15

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US (1) US12259538B2 (enExample)
JP (1) JP7399168B2 (enExample)
DE (1) DE102018222271A1 (enExample)
WO (1) WO2020126419A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024162288A1 (ja) * 2023-01-31 2024-08-08 国立研究開発法人理化学研究所 光学観察用の構造及びその作成方法、試料の観察方法、顕微鏡観察用のマウント液
EP4614207A1 (en) * 2024-03-05 2025-09-10 Leica Microsystems CMS GmbH Sample positioning device and light sheet microscope
WO2025240986A1 (en) * 2024-05-21 2025-11-27 Gmi - Gregor-Mendel-Institut Für Molekulare Pflanzenbiologie Gmbh Microscope and microscopy method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013545138A (ja) 2010-11-07 2013-12-19 カウンシル フォー サイエンティフィック アンド インダストリアル リサーチ オンチップ型4dライトフィールド顕微鏡
JP2015118378A (ja) 2013-12-18 2015-06-25 カール ツァイス マイクロスコピー ゲーエムベーハーCarl Zeiss Microscopy Gmbh 顕微鏡およびspim顕微鏡検査方法
JP2017146442A (ja) 2016-02-17 2017-08-24 オリンパス株式会社 標本の観察方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007065711A1 (en) * 2005-12-09 2007-06-14 Europäisches Laboratorium für Molekularbiologie (EMBL) Miscroscope specimen holder
DE102012013163B4 (de) 2012-07-02 2022-08-25 Carl Zeiss Microscopy Gmbh Mikroskop und Verfahren zur Lichtscheibenmikroskopie
DE102013211426A1 (de) * 2013-06-18 2014-12-18 Leica Microsystems Cms Gmbh Verfahren und optische Vorrichtung zum mikroskopischen Untersuchen einer Vielzahl von Proben
DE102013107298B4 (de) 2013-07-10 2025-07-17 Carl Zeiss Microscopy Gmbh Anordnung zur Lichtblattmikroskopie
WO2016030464A1 (en) * 2014-08-28 2016-03-03 Single Technologies Ab High throughput biochemical screening
US20170139195A1 (en) 2015-11-14 2017-05-18 Guy Kennedy Microscopy Safety Dome
DE102016212019A1 (de) 2016-07-01 2018-01-04 Carl Zeiss Microscopy Gmbh Neigungsmessung und -korrektur des Deckglases im Strahlengang eines Mikroskops
US10310248B2 (en) * 2016-08-18 2019-06-04 Olympus Corporation Microscope including a medium container containing an immersion medium in which a specimen container containing an immersion medium and a sample is immersed
DE102017204325A1 (de) 2017-03-15 2018-09-20 Carl Zeiss Microscopy Gmbh Anordnung, Mikroskop und Verfahren zur TIRF-Mikroskopie
DE102017217389A1 (de) 2017-09-29 2019-04-04 Carl Zeiss Microscopy Gmbh Optische Linse zur Verwendung in einer Medienzuführungsvorrichtung sowie Objektiv, Medienzuführungsvorrichtung und Mikroskop

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013545138A (ja) 2010-11-07 2013-12-19 カウンシル フォー サイエンティフィック アンド インダストリアル リサーチ オンチップ型4dライトフィールド顕微鏡
JP2015118378A (ja) 2013-12-18 2015-06-25 カール ツァイス マイクロスコピー ゲーエムベーハーCarl Zeiss Microscopy Gmbh 顕微鏡およびspim顕微鏡検査方法
JP2017146442A (ja) 2016-02-17 2017-08-24 オリンパス株式会社 標本の観察方法

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DE102018222271A1 (de) 2020-06-25
US12259538B2 (en) 2025-03-25
JP2022521567A (ja) 2022-04-11
US20220043244A1 (en) 2022-02-10
WO2020126419A1 (de) 2020-06-25

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