JP7319027B2 - 培養培地 - Google Patents

培養培地 Download PDF

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JP7319027B2
JP7319027B2 JP2017528087A JP2017528087A JP7319027B2 JP 7319027 B2 JP7319027 B2 JP 7319027B2 JP 2017528087 A JP2017528087 A JP 2017528087A JP 2017528087 A JP2017528087 A JP 2017528087A JP 7319027 B2 JP7319027 B2 JP 7319027B2
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culture medium
organoids
cells
lung
cell
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JP2018503360A (ja
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ラース ノーマン ザックス
ヤルノ ドロスト
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Koninklijke Nederlandse Akademie van Wetenschappen
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Koninklijke Nederlandse Akademie van Wetenschappen
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    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0695—Stem cells; Progenitor cells; Precursor cells
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13—Tumour cells, irrespective of tissue of origin
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/42—Respiratory system, e.g. lungs, bronchi or lung cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N5/0623—Stem cells
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629—Keratinocytes; Whole skin
    • C12N5/063—Kereatinocyte stem cells; Keratinocyte progenitors
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    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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JP2017528087A 2014-11-27 2015-11-27 培養培地 Active JP7319027B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2021187540A JP2022028828A (ja) 2014-11-27 2021-11-18 培養培地
JP2023197836A JP2024016281A (ja) 2014-11-27 2023-11-22 培養培地

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB1421092.6A GB201421092D0 (en) 2014-11-27 2014-11-27 Culture medium
GB1421092.6 2014-11-27
GB1507834.8A GB2532814A (en) 2014-11-27 2015-05-07 Culture medium
GB1507834.8 2015-05-07
PCT/EP2015/077990 WO2016083613A2 (en) 2014-11-27 2015-11-27 Culture medium

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JP2021187540A Division JP2022028828A (ja) 2014-11-27 2021-11-18 培養培地

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JP2018503360A JP2018503360A (ja) 2018-02-08
JP7319027B2 true JP7319027B2 (ja) 2023-08-01

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JP2017528087A Active JP7319027B2 (ja) 2014-11-27 2015-11-27 培養培地
JP2021187540A Pending JP2022028828A (ja) 2014-11-27 2021-11-18 培養培地
JP2023197836A Pending JP2024016281A (ja) 2014-11-27 2023-11-22 培養培地

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JP2023197836A Pending JP2024016281A (ja) 2014-11-27 2023-11-22 培養培地

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Country Link
US (2) US11130943B2 (https=)
EP (1) EP3224346B1 (https=)
JP (3) JP7319027B2 (https=)
AU (3) AU2015352351B2 (https=)
CA (1) CA2968736A1 (https=)
GB (2) GB201421092D0 (https=)
HK (1) HK1245323A1 (https=)
WO (1) WO2016083613A2 (https=)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
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EP2393917B1 (en) 2009-02-03 2016-04-06 Koninklijke Nederlandse Akademie van Wetenschappen Culture medium for epithelial stem cells and organoids comprising said stem cells.
EP2412800A1 (en) 2010-07-29 2012-02-01 Koninklijke Nederlandse Akademie van Wetenschappen Liver organoid, uses thereof and culture method for obtaining them
US9719068B2 (en) 2010-05-06 2017-08-01 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
US10006904B2 (en) 2011-12-19 2018-06-26 Umc Utrecht Holding B.V. Rapid quantitative assay to measure CFTR function in a primary intestinal culture model
CA2949171A1 (en) 2014-05-16 2015-11-19 Koninklijke Nederlandse Akademie Van Wetenschappen Improved culture method for organoids
SG10201801654RA (en) 2014-05-28 2018-04-27 Childrens Hospital Med Ct Methods and systems for converting precursor cells into gastric tissues through directed differentiation
AU2015331848B2 (en) 2014-10-17 2022-03-03 Children's Hospital Medical Center, D/B/A Cincinnati Children's Hospital Medical Center In vivo model of human small intestine using pluripotent stem cells and methods of making and using same
GB201421092D0 (en) 2014-11-27 2015-01-14 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium
GB201421094D0 (en) 2014-11-27 2015-01-14 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium
GB201603569D0 (en) 2016-03-01 2016-04-13 Koninklijke Nederlandse Akademie Van Wetenschappen Improved differentiation method
CN109415685B (zh) 2016-05-05 2023-07-04 儿童医院医疗中心 用于体外制造胃底组织的方法和与其相关的组合物
GB201611982D0 (en) 2016-07-11 2016-08-24 Cellesce Ltd Cell culture
US20190161737A1 (en) * 2016-07-27 2019-05-30 Georgetown University Process for continuous cell culture of cancer cells and cancer stem cells
IT201600099380A1 (it) * 2016-10-04 2018-04-04 Univ Bologna Alma Mater Studiorum Composizioni, dispositivi e metodi per il controllo in vitro del microambiente chimico in colture cellulari
JP2019534041A (ja) * 2016-10-06 2019-11-28 トランスジェネックス ナノバイオテック、インコーポレイテッド がん幹細胞（ｃｓｃ）増大のための方法
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