JP7295032B2 - 凍結乾燥方法および関連製品 - Google Patents
凍結乾燥方法および関連製品 Download PDFInfo
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- JP7295032B2 JP7295032B2 JP2019559711A JP2019559711A JP7295032B2 JP 7295032 B2 JP7295032 B2 JP 7295032B2 JP 2019559711 A JP2019559711 A JP 2019559711A JP 2019559711 A JP2019559711 A JP 2019559711A JP 7295032 B2 JP7295032 B2 JP 7295032B2
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Images
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/042—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum for drying articles or discrete batches of material in a continuous or semi-continuous operation, e.g. with locks or other air tight arrangements for charging/discharging
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof containing fruit or vegetable juices
- A23L2/08—Concentrating or drying of juices
- A23L2/12—Concentrating or drying of juices by freezing
- A23L2/14—Concentrating or drying of juices by freezing and sublimation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B15/00—Machines or apparatus for drying objects with progressive movement; Machines or apparatus with progressive movement for drying batches of material in compact form
- F26B15/02—Machines or apparatus for drying objects with progressive movement; Machines or apparatus with progressive movement for drying batches of material in compact form with movement in the whole or part of a circle
- F26B15/04—Machines or apparatus for drying objects with progressive movement; Machines or apparatus with progressive movement for drying batches of material in compact form with movement in the whole or part of a circle in a horizontal plane
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B25/00—Details of general application not covered by group F26B21/00 or F26B23/00
- F26B25/001—Handling, e.g. loading or unloading arrangements
- F26B25/003—Handling, e.g. loading or unloading arrangements for articles
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/048—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum in combination with heat developed by electro-magnetic means, e.g. microwave energy
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Drying Of Solid Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762500466P | 2017-05-02 | 2017-05-02 | |
| US62/500,466 | 2017-05-02 | ||
| PCT/US2018/030629 WO2018204484A1 (en) | 2017-05-02 | 2018-05-02 | Freeze-drying methods and related products |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020518780A JP2020518780A (ja) | 2020-06-25 |
| JP2020518780A5 JP2020518780A5 (enExample) | 2021-06-17 |
| JP7295032B2 true JP7295032B2 (ja) | 2023-06-20 |
Family
ID=64017000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019559711A Active JP7295032B2 (ja) | 2017-05-02 | 2018-05-02 | 凍結乾燥方法および関連製品 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US11340014B2 (enExample) |
| EP (1) | EP3619489A4 (enExample) |
| JP (1) | JP7295032B2 (enExample) |
| WO (1) | WO2018204484A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY197621A (en) * | 2014-08-04 | 2023-06-28 | Genentech Inc | Apparatus and methods for sealing a medicament within a medical delivery device |
| WO2018204484A1 (en) * | 2017-05-02 | 2018-11-08 | Massachusetts Institute Of Technology | Freeze-drying methods and related products |
| EP3590893A1 (en) * | 2018-07-04 | 2020-01-08 | Elajo Technology Solutions AB | Method and arrangement for dewaterng sludge |
| DE102018218758A1 (de) * | 2018-11-02 | 2020-05-07 | OPTIMA pharma GmbH | Vorrichtung und Verfahren zum Gefriertrocknen |
| CN109974426A (zh) * | 2019-01-08 | 2019-07-05 | 林遂铭 | 一种干燥机 |
| US10921058B2 (en) * | 2019-01-27 | 2021-02-16 | Vinamit Usa Llc | Fully automatic convection current vacuum freeze drying method |
| US11243029B2 (en) * | 2019-04-26 | 2022-02-08 | Purdue Research Foundation | Process monitoring and control for lyophilization using a wireless sensor network |
| GB2589347A (en) * | 2019-11-27 | 2021-06-02 | Fluorogenics Ltd | Freeze-drying apparatus and method |
| US12402217B2 (en) * | 2020-03-30 | 2025-08-26 | Midea Group Co., Ltd. | Microwave cooking appliance with adaptive thermal sensing cycle |
| TWI860477B (zh) * | 2020-05-18 | 2024-11-01 | 日商Ｍｉｉ股份有限公司 | 真空凍結乾燥裝置及真空凍結乾燥方法 |
| EP4161690A4 (en) * | 2020-06-05 | 2024-06-19 | Merck Sharp & Dohme LLC | DEVICE AND METHOD FOR MICROWAVE VACUUM DRYING OF STERILE PRODUCTS |
| WO2022046273A1 (en) * | 2020-08-31 | 2022-03-03 | Massachusetts Institute Of Technology | Lyophilization systems and methods |
| US11287185B1 (en) | 2020-09-09 | 2022-03-29 | Stay Fresh Technology, LLC | Freeze drying with constant-pressure and constant-temperature phases |
| CA3141419A1 (en) * | 2021-01-18 | 2022-07-18 | Rodrick Jolly | Vacuum grain drying apparatus |
| JP7085088B1 (ja) * | 2021-08-03 | 2022-06-16 | 株式会社エムアイアイ | 凍結乾燥物 |
| EP4590478A1 (en) * | 2021-09-21 | 2025-07-30 | Stephen B. Maguire | Resin drying systems with capability to continuously supply dried resin |
| CN114136058A (zh) * | 2021-12-13 | 2022-03-04 | 上海德瀛睿创半导体科技有限公司 | 烘干设备及加工系统 |
| NL2030238B1 (en) * | 2021-12-22 | 2023-06-29 | Rheavita Bv | Device and method for freeze-drying liquid-containing composition |
| CN115176958B (zh) * | 2022-07-01 | 2024-01-09 | 福建利众诚食品有限公司 | 基于冻干食品的转载方法及转载装置 |
| CN115342603A (zh) * | 2022-08-30 | 2022-11-15 | 中国科学院理化技术研究所 | 循环风冷冻干燥系统及方法 |
| JP7680062B2 (ja) * | 2023-07-03 | 2025-05-20 | 大川原化工機株式会社 | 真空噴霧凍結乾燥装置における粉末体の取出装置及び真空噴霧凍結乾燥装置における粉末体の取出方法、並びに、真空噴霧凍結乾燥装置 |
| CN116659210B (zh) * | 2023-07-26 | 2023-10-27 | 江苏安欣医疗科技有限公司 | 用于直线型切割吻合器生产加工的随动烘干输送机 |
| CN119197046B (zh) * | 2024-07-10 | 2025-11-14 | 天津科技大学 | 单位剂量灌装的药品旋转冷冻干燥装置 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007535652A (ja) | 2004-05-01 | 2007-12-06 | アグリサーチ リミティド | 乾燥工程及び装置 |
| US20100251560A1 (en) | 2008-06-27 | 2010-10-07 | Gerald Thomas | Holder |
| US20140215845A1 (en) | 2011-09-06 | 2014-08-07 | RheaVita B.V. | Method and system for freeze-drying injectable compositions, in particular pharmaceutical compositions |
| WO2017043485A1 (ja) | 2015-09-07 | 2017-03-16 | 持田製薬株式会社 | アルギン酸凍結乾燥製剤 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2285336A (en) | 1939-02-25 | 1942-06-02 | Owens Illinois Glass Co | Automatic drying apparatus |
| DE1178788B (de) * | 1959-10-07 | 1964-09-24 | Leybold Hochvakuum Anlagen | Rohrfoermige, aus Teilkammern zusammen-gesetzte Vakuum-Gefriertrocknungsanlage |
| US3203108A (en) | 1962-11-28 | 1965-08-31 | Samuel M Broadwin | Centrifugal freeze drying apparatus |
| DE2615815A1 (de) | 1976-04-10 | 1977-10-27 | Boehringer Mannheim Gmbh | Maschine zum kontinuierlichen herstellen und verpacken von gefriertrocknungsgut |
| GB9505523D0 (en) * | 1995-03-18 | 1995-05-03 | Wellcome Found | Lyophilization process |
| US5723508A (en) * | 1996-01-25 | 1998-03-03 | Northwestern University | Method of fabricating emulsion freeze-dried scaffold bodies and resulting products |
| GB0013714D0 (en) | 2000-06-07 | 2000-07-26 | Acton Elizabeth | Method and apparatus for freezing tissue |
| GB0525115D0 (en) * | 2005-12-09 | 2006-01-18 | Oxford Biosensors Ltd | Freeze drying of target substances |
| PT2525675E (pt) * | 2010-01-18 | 2015-08-21 | Enwave Corp | Secagem a vácuo por microondas de matérias orgânicas |
| ITMI20131016A1 (it) * | 2013-06-19 | 2014-12-20 | I M A Ind Macchine Automatic He S P A | Sistema di alimentazione in una macchina liofilizzatrice per il settore farmaceutico |
| US11384980B2 (en) * | 2013-10-17 | 2022-07-12 | Joseph P. Triglia, Jr. | System and method for reducing moisture in materials or plants using microwave radiation and RF energy |
| WO2015191599A2 (en) * | 2014-06-09 | 2015-12-17 | Terumo Bct, Inc. | Lyophilization |
| WO2015188248A1 (en) * | 2014-06-11 | 2015-12-17 | Enwave Corporation | Microwave vacuum-drying of organic materials |
| WO2016191799A1 (en) | 2015-06-04 | 2016-12-08 | Freeze Dry Industries Pty Ltd | Freeze drying improvements |
| CN204917150U (zh) | 2015-07-10 | 2015-12-30 | 楚天科技股份有限公司 | 一种输瓶装置及其冻干机进出料系统 |
| CN105928327A (zh) | 2016-06-15 | 2016-09-07 | 超滤动力（安徽）有限公司 | 多单元并联式冷冻型干燥机 |
| SI3392584T1 (sl) * | 2017-04-21 | 2020-09-30 | Gea Lyophil Gmbh | Zamrzovalni sušilnik in postopek za induciranje nukleacije v proizvodih |
| WO2018204484A1 (en) * | 2017-05-02 | 2018-11-08 | Massachusetts Institute Of Technology | Freeze-drying methods and related products |
| US20210190425A1 (en) * | 2017-11-22 | 2021-06-24 | Ima Life North America Inc. | Spray freeze drying on a substrate |
| US10921058B2 (en) * | 2019-01-27 | 2021-02-16 | Vinamit Usa Llc | Fully automatic convection current vacuum freeze drying method |
| US11054185B1 (en) * | 2020-02-24 | 2021-07-06 | Lyophilization Technology, Inc. | Apparatus for lyophilization of products contained in product delivery units |
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2018
- 2018-05-02 WO PCT/US2018/030629 patent/WO2018204484A1/en not_active Ceased
- 2018-05-02 JP JP2019559711A patent/JP7295032B2/ja active Active
- 2018-05-02 EP EP18794019.2A patent/EP3619489A4/en active Pending
- 2018-05-02 US US16/610,485 patent/US11340014B2/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007535652A (ja) | 2004-05-01 | 2007-12-06 | アグリサーチ リミティド | 乾燥工程及び装置 |
| US20100251560A1 (en) | 2008-06-27 | 2010-10-07 | Gerald Thomas | Holder |
| US20140215845A1 (en) | 2011-09-06 | 2014-08-07 | RheaVita B.V. | Method and system for freeze-drying injectable compositions, in particular pharmaceutical compositions |
| WO2017043485A1 (ja) | 2015-09-07 | 2017-03-16 | 持田製薬株式会社 | アルギン酸凍結乾燥製剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3619489A4 (en) | 2021-04-14 |
| JP2020518780A (ja) | 2020-06-25 |
| WO2018204484A1 (en) | 2018-11-08 |
| US20200158431A1 (en) | 2020-05-21 |
| US11340014B2 (en) | 2022-05-24 |
| US20210180865A9 (en) | 2021-06-17 |
| EP3619489A1 (en) | 2020-03-11 |
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