JP7289795B2 - ファルネシルトランスフェラーゼ阻害剤を用いてがんを治療する方法 - Google Patents

ファルネシルトランスフェラーゼ阻害剤を用いてがんを治療する方法 Download PDF

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JP7289795B2
JP7289795B2 JP2019566054A JP2019566054A JP7289795B2 JP 7289795 B2 JP7289795 B2 JP 7289795B2 JP 2019566054 A JP2019566054 A JP 2019566054A JP 2019566054 A JP2019566054 A JP 2019566054A JP 7289795 B2 JP7289795 B2 JP 7289795B2
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cxcl12
cancer
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JP2020508351A (ja
JP2020508351A5 (https=
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グアルベルト，アントニオ
ショルツ，キャサリン・ローズ
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クラ オンコロジー， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2019566054A 2017-02-21 2018-02-21 ファルネシルトランスフェラーゼ阻害剤を用いてがんを治療する方法 Active JP7289795B2 (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201762461602P 2017-02-21 2017-02-21
US62/461,602 2017-02-21
US201762507749P 2017-05-17 2017-05-17
US62/507,749 2017-05-17
US201762519819P 2017-06-14 2017-06-14
US62/519,819 2017-06-14
US15/820,157 2017-11-21
US15/820,012 US10137121B2 (en) 2017-02-21 2017-11-21 Methods of treating cancer with farnesyltransferase inhibitors
US15/820,157 US9956215B1 (en) 2017-02-21 2017-11-21 Methods of treating cancer with farnesyltransferase inhibitors
US15/820,012 2017-11-21
US201762596653P 2017-12-08 2017-12-08
US62/596,653 2017-12-08
PCT/US2018/018989 WO2018156609A1 (en) 2017-02-21 2018-02-21 Methods of treating cancer with farnesyltransferase inhibitors

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JP2020508351A JP2020508351A (ja) 2020-03-19
JP2020508351A5 JP2020508351A5 (https=) 2021-04-01
JP7289795B2 true JP7289795B2 (ja) 2023-06-12

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EP (3) EP3542800B1 (https=)
JP (1) JP7289795B2 (https=)
KR (3) KR102138904B1 (https=)
CN (4) CN109475550A (https=)
AU (3) AU2018225566B2 (https=)
BR (1) BR112019017375A2 (https=)
CA (1) CA3053795A1 (https=)
ES (2) ES2892157T3 (https=)
IL (1) IL268722A (https=)
MX (2) MX394077B (https=)
PH (1) PH12019501918A1 (https=)
SG (1) SG11201907594TA (https=)
TW (3) TWI738314B (https=)
WO (1) WO2018156609A1 (https=)

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Publication number Priority date Publication date Assignee Title
US10137121B2 (en) 2017-02-21 2018-11-27 Kura Oncology, Inc. Methods of treating cancer with farnesyltransferase inhibitors
MX2020001207A (es) * 2017-08-07 2020-03-20 Kura Oncology Inc Metodos de tratamiento del cancer con inhibidores de farnesiltransferasa.
US20220143006A1 (en) * 2019-03-15 2022-05-12 Kura Oncology, Inc. Methods of treating cancer with farnesyltransferase inhibitors
WO2025224720A1 (en) * 2024-04-24 2025-10-30 Biolinerx Ltd. Methods of selecting treatment regimen against solid tumors

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Also Published As

Publication number Publication date
KR20190087661A (ko) 2019-07-24
WO2018156609A1 (en) 2018-08-30
KR20180123723A (ko) 2018-11-19
TW201834652A (zh) 2018-10-01
EP3542800B1 (en) 2022-06-01
JP2020508351A (ja) 2020-03-19
TW201929903A (zh) 2019-08-01
SG11201907594TA (en) 2019-09-27
KR20200090982A (ko) 2020-07-29
KR102003179B1 (ko) 2019-07-23
MX394077B (es) 2025-03-24
AU2019203548A1 (en) 2019-06-13
AU2018225566A1 (en) 2018-11-08
CN109999037A (zh) 2019-07-12
AU2019203548C1 (en) 2020-01-23
KR102138904B1 (ko) 2020-07-28
AU2018225566B2 (en) 2019-11-07
TWI738314B (zh) 2021-09-01
CN109475550A (zh) 2019-03-15
BR112019017375A2 (pt) 2020-03-31
EP3432883B1 (en) 2021-07-28
MX2022008843A (es) 2022-08-10
CN114796218A (zh) 2022-07-29
ES2892157T3 (es) 2022-02-02
TWI663974B (zh) 2019-07-01
EP3432883A1 (en) 2019-01-30
TW202031260A (zh) 2020-09-01
MX2019009821A (es) 2019-12-02
CN114712354A (zh) 2022-07-08
CA3053795A1 (en) 2018-08-30
PH12019501918A1 (en) 2020-06-01
AU2019246922A1 (en) 2019-10-31
TWI693074B (zh) 2020-05-11
EP4119142A1 (en) 2023-01-18
IL268722A (en) 2019-10-31
AU2019203548B2 (en) 2019-08-15
EP3542800A1 (en) 2019-09-25
ES2927228T3 (es) 2022-11-03

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