TWI738314B - 以法呢基轉移酶(farnesyltransferase)抑制劑治療癌症之方法 - Google Patents
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A—HUMAN NECESSITIES
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- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- General Chemical & Material Sciences (AREA)
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- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| US62/461,602 | 2017-02-21 | ||
| US201762507749P | 2017-05-17 | 2017-05-17 | |
| US62/507,749 | 2017-05-17 | ||
| US201762519819P | 2017-06-14 | 2017-06-14 | |
| US62/519,819 | 2017-06-14 | ||
| US15/820,012 | 2017-11-21 | ||
| US15/820,012 US10137121B2 (en) | 2017-02-21 | 2017-11-21 | Methods of treating cancer with farnesyltransferase inhibitors |
| US15/820,157 | 2017-11-21 | ||
| US15/820,157 US9956215B1 (en) | 2017-02-21 | 2017-11-21 | Methods of treating cancer with farnesyltransferase inhibitors |
| US201762596653P | 2017-12-08 | 2017-12-08 | |
| US62/596,653 | 2017-12-08 |
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| TW107105861A TWI663974B (zh) | 2017-02-21 | 2018-02-21 | 以法呢基轉移酶(farnesyltransferase)抑制劑治療癌症之方法 |
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| MX2020001207A (es) * | 2017-08-07 | 2020-03-20 | Kura Oncology Inc | Metodos de tratamiento del cancer con inhibidores de farnesiltransferasa. |
| US20220143006A1 (en) * | 2019-03-15 | 2022-05-12 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
| WO2025224720A1 (en) * | 2024-04-24 | 2025-10-30 | Biolinerx Ltd. | Methods of selecting treatment regimen against solid tumors |
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