JP7270254B2 - 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク - Google Patents

改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク Download PDF

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JP7270254B2
JP7270254B2 JP2019568598A JP2019568598A JP7270254B2 JP 7270254 B2 JP7270254 B2 JP 7270254B2 JP 2019568598 A JP2019568598 A JP 2019568598A JP 2019568598 A JP2019568598 A JP 2019568598A JP 7270254 B2 JP7270254 B2 JP 7270254B2
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アルビン アール． レベック，
クリス ドワイヤー，
クレイグ ラボダ，
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    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6432—Quenching
    • G—PHYSICS
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

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  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2019568598A 2017-06-16 2018-06-12 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク Active JP7270254B2 (ja)

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JP2023026034A JP7601432B2 (ja) 2017-06-16 2023-02-22 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク
JP2024186553A JP2025010178A (ja) 2017-06-16 2024-10-23 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク

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US201762521192P 2017-06-16 2017-06-16
US62/521,192 2017-06-16
US201762527451P 2017-06-30 2017-06-30
US62/527,451 2017-06-30
US201762551616P 2017-08-29 2017-08-29
US62/551,616 2017-08-29
PCT/US2018/037076 WO2018231805A2 (en) 2017-06-16 2018-06-12 Resonator networks for improved label detection, computation, analyte sensing, and tunable random number generation

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JP2023026034A Active JP7601432B2 (ja) 2017-06-16 2023-02-22 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク
JP2024186553A Withdrawn JP2025010178A (ja) 2017-06-16 2024-10-23 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク

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JP2024186553A Withdrawn JP2025010178A (ja) 2017-06-16 2024-10-23 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク

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US (3) US11674901B2 (https=)
EP (2) EP4075133A3 (https=)
JP (3) JP7270254B2 (https=)
KR (2) KR102584549B1 (https=)
CN (2) CN116519642A (https=)
AU (1) AU2018282868B2 (https=)
CA (1) CA3067362C (https=)
IL (1) IL271386B2 (https=)
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Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119220109A (zh) 2018-03-30 2024-12-31 贝克顿·迪金森公司 含侧基发色团的水溶性聚合染料
WO2020189741A1 (ja) * 2019-03-20 2020-09-24 国立大学法人大阪大学 信号処理装置及び信号処理方法
CN114555125A (zh) 2019-10-25 2022-05-27 菲托尼尔斯股份有限公司 多核苷酸连接的生物缀合物及其制备和使用方法
CN114441752B (zh) * 2020-11-03 2024-11-26 中国科学院苏州纳米技术与纳米仿生研究所 一种筛选方法
WO2022125755A1 (en) 2020-12-10 2022-06-16 Thermo Fisher Scientific Inc. Method and composition for multiplexed and multimodal single cell analysis
EP4259823A2 (en) 2020-12-10 2023-10-18 Phitonex, Inc. Methods of signal amplification
WO2022216450A1 (en) 2021-04-07 2022-10-13 Becton, Dickinson And Company Water-soluble fluorescent polymeric dyes
US12579411B2 (en) 2021-12-29 2026-03-17 International Business Machines Corporation Resonator network based neural network
WO2024157278A1 (en) 2023-01-27 2024-08-02 Invitrogen Bioservices India Private Limited Rapid expression and screening of cell penetrating peptides
EP4709877A2 (en) 2023-05-12 2026-03-18 Life Technologies Corporation Methods and kits for detecting endotoxin

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020160411A1 (en) 1999-12-14 2002-10-31 Research Corporation Technologies, Inc. Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same
JP2012515905A (ja) 2009-01-22 2012-07-12 ウニベルジテート ポツダム 多重化ｆｒｅｔ解析により試料中の検体を検出する方法及びキット
US20130309671A1 (en) 2012-05-18 2013-11-21 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Spectro-Temporal Optical Encoding of Information Using a Time-Gated Fluorescence Resonance Energy Transfer (FRET)
US20150293022A1 (en) 2014-04-15 2015-10-15 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Use of Modular Nucleic Acid Scaffolds to Create Nanoscale Energy Harvesting and Focusing Arrays
JP2016014033A (ja) 2009-02-18 2016-01-28 カーネギー メロン ユニバーシティ 明検出のためのクエンチャー付加デンドリマー色素

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1067134B1 (en) * 1991-11-07 2004-07-28 Nanotronics, Inc. Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system
US7348181B2 (en) 1997-10-06 2008-03-25 Trustees Of Tufts College Self-encoding sensor with microspheres
US6207392B1 (en) 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
US20020115092A1 (en) * 2000-11-08 2002-08-22 The Scripps Research Institute Energy transfer labels with mechanically linked fluorophores
US10001475B2 (en) 2002-06-20 2018-06-19 The Regents Of The University Of California Light harvesting multichromophore compositions and methods of using the same
US7270956B2 (en) 2002-08-26 2007-09-18 The Regents Of The University Of California Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores
WO2004001379A2 (en) 2002-06-20 2003-12-31 The Regents Of The University Of California Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores
WO2004077014A2 (en) 2003-02-13 2004-09-10 The Regents Of The University Of California Methods and compositions for detection and analysis of polynucleotide-binding protein interactions using light harvesting multichromophores
US7754832B2 (en) 2003-02-28 2010-07-13 The Regents Of The University Of California Block copolyolefins possessing a tapered structure
US7825200B2 (en) 2003-02-28 2010-11-02 The Regents Of The University Of California Controlled free radical grafting from polyolefins
AU2004267806A1 (en) 2003-08-20 2005-03-03 Bg Medicine, Inc. Methods and systems for profiling biological systems
DE112004001737B4 (de) 2003-09-17 2016-08-11 The Regents Of The University Of California Verfahren umfassend lösliche, konjugierte Polymere zur Ausbildung benachbarter Schichten auf einem Substrat oder zum Hinzufügen einer Polymerschicht zu einem Substrat, mehrschichtige elektronische Vorrichtung und Verwendung in elektronischen Bauteilen
US7830085B2 (en) 2003-10-06 2010-11-09 The Regents Of The University Of California White electrophosphorescence from semiconducting polymer blends
JP4511857B2 (ja) * 2004-03-24 2010-07-28 国立大学法人京都大学 フォトニック結晶を応用したセンサおよび検出対象物質の検出方法
KR20070018083A (ko) * 2004-05-27 2007-02-13 쓰리엠 이노베이티브 프로퍼티즈 컴파니 광대역 광원으로 여기된 유전체 미세공동 형광 센서
US7271379B2 (en) * 2004-05-27 2007-09-18 3M Innovative Properties Company Dielectric microcavity fluorosensors excited with a broadband light source
US20060021673A1 (en) 2004-07-27 2006-02-02 Stephan Rodewald Self-sealing apparatus for chemical reaction vessel
US8795781B2 (en) 2004-09-03 2014-08-05 The Regents Of The University Of California Methods and devices utilizing soluble conjugated polymers
JP2008512523A (ja) 2004-09-03 2008-04-24 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 可溶性共役ポリマー
EP2502946B1 (en) 2005-01-10 2017-10-04 The Regents of The University of California Cationic conjugated polymers suitable for strand-specific polynucleiotide detection in homogeneous and solid state assays
DE112006000495B4 (de) 2005-03-01 2017-11-09 The Regents Of The University Of California Mehrschichtige Licht emittierende Polymer-Diode für Festkörper Beleuchtungs-Anwendungen
WO2007027159A1 (en) 2005-08-30 2007-03-08 Agency For Science, Technology And Research Water-soluble fluorescent particle comprising entangled fluorescent polymer and amphiphilic molecule
US20070275388A1 (en) 2006-05-25 2007-11-29 Daniel Ryan Dendrimers that possess a single target annealing site and uses thereof
JP5088034B2 (ja) 2006-08-14 2012-12-05 ソニー株式会社 物質の検出等に有用な核酸鎖とその方法
CN101553579B (zh) 2006-10-06 2016-01-20 赛里根有限公司 用于定向生物标志物信号放大的荧光方法和材料
US7796262B1 (en) * 2007-05-31 2010-09-14 Nomadics, Inc. Integrated optical resonator device for measuring chemical and biological analyte concentrations
US20090325211A1 (en) 2007-10-06 2009-12-31 Ye Fang System and method for dual-detection of a cellular response
US8309306B2 (en) 2008-11-12 2012-11-13 Nodality, Inc. Detection composition
US8218151B2 (en) 2009-03-12 2012-07-10 Tel Aviv University Future Technology Development Ltd Light-emitting intra-cavity interferometric sensors
SG177355A1 (en) 2009-06-26 2012-02-28 Sirigen Inc Signal amplified biological detection with conjugated polymers
FR2950431B1 (fr) * 2009-09-24 2011-12-09 Commissariat Energie Atomique Dispositif et procede de reconstruction spatiale d'une cartographie de fluorescence
AU2010301128B2 (en) 2009-09-30 2014-09-18 Quantapore, Inc. Ultrafast sequencing of biological polymers using a labeled nanopore
JP6073684B2 (ja) 2010-01-19 2017-02-01 シリゲン セカンド リミテッド 指向性バイオマーカーシグナル増幅のための新規の試薬
EP3266881B1 (en) 2010-11-05 2019-12-25 Genalyte, Inc. Optical analyte detection systems and methods of use
WO2012074853A1 (en) 2010-11-22 2012-06-07 The Regents Of The University Of California Organic small molecule semiconducting chromophores for use in organic electronic devices
CN102590160A (zh) 2011-01-13 2012-07-18 索尼公司 荧光量子点/纳米金属颗粒偶联物及其制备和应用
WO2012174561A2 (en) 2011-06-17 2012-12-20 The Regents Of The University Of California REGIOREGULAR PYRIDAL[2,1,3]THIADIAZOLE π-CONJUGATED COPOLYMERS FOR ORGANIC SEMICONDUCTORS
US20130032791A1 (en) 2011-06-24 2013-02-07 Bazan Guillermo C Conjugated polymers having an imine group at the intrachain electron donor bridgehead position useful in electronic devices
US20160150963A1 (en) 2011-09-26 2016-06-02 Michael Lee Roukes One-photon integrated neurophotonic systems
US20130247989A1 (en) 2012-03-23 2013-09-26 The Regents Of The University Of California Inert solution-processable molecular chromophores for organic electronic devices
US8729221B2 (en) 2012-04-25 2014-05-20 The Regents Of The University Of California Conjugated copolymers chiral side chain for organic thin film transistors
EP3019559A4 (en) 2013-08-22 2017-04-05 Sony Corporation Water soluble fluorescent or colored dyes and methods for their use
CN105917003A (zh) * 2013-11-17 2016-08-31 宽腾矽公司 用于生物和化学试样的快速分析的有源像素集成装置
US9689877B2 (en) 2014-01-16 2017-06-27 Sony Corporation Water soluble fluorescent or colored dyes and methods for their use
EP2940150A1 (en) * 2014-04-29 2015-11-04 Baseclick GmbH Self-assembly of DNA Origami: a new diganostic tool
WO2015176034A1 (en) 2014-05-15 2015-11-19 Two Pore Guys, Inc. Scaffold data storage and target detection in a sample using a nanopore
CN106796175B (zh) * 2014-08-08 2021-01-05 宽腾矽公司 用于探测、检测和分析分子的光学系统和检测芯片
EP3191840B1 (en) 2014-09-12 2020-04-08 Purdue Research Foundation Metal-antibody tagging and plasma-based detection
JP6806694B2 (ja) 2015-02-26 2021-01-06 ソニー株式会社 共役基を含む水溶性蛍光染料または有色染料
US10865310B2 (en) 2015-05-11 2020-12-15 Sony Corporation Of America Ultra bright dimeric or polymeric dyes
US10487173B2 (en) 2015-11-11 2019-11-26 The Regents Of The University Of California Fluorine substitution influence on benzo[2,1,3]thiodiazole based polymers for field-effect transistor applications
WO2017143171A1 (en) 2016-02-19 2017-08-24 Genisphere Llc Nucleic acid carriers and therapeutic methods of use
US10465233B2 (en) * 2016-03-25 2019-11-05 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Time-resolved nucleic acid hybridization beacons
AU2017240154B2 (en) 2016-04-01 2021-08-12 Sony Group Corporation Ultra bright dimeric or polymeric dyes
US11434377B2 (en) 2016-04-01 2022-09-06 Sony Corporation Ultra bright dimeric or polymeric dyes with rigid spacing groups
US9851359B2 (en) 2016-04-06 2017-12-26 Sony Corporation Of America Ultra bright dimeric or polymeric dyes with spacing linker groups
US20170309825A1 (en) 2016-04-25 2017-10-26 The Regents Of The University Of California Novel weak donor-acceptor conjugated copolymers for field- effect transistor applications
US11370922B2 (en) 2016-05-10 2022-06-28 Sony Corporation Ultra bright polymeric dyes with peptide backbones
WO2017197014A2 (en) 2016-05-10 2017-11-16 Sony Corporation Compositions comprising a polymeric dye and a cyclodextrin and uses thereof
KR102526802B1 (ko) 2016-05-11 2023-05-02 소니그룹주식회사 초고명도 이량체성 또는 중합체성 염료
WO2017214165A1 (en) 2016-06-06 2017-12-14 Sony Corporation Ionic polymers comprising fluorescent or colored reporter groups
JP7312929B2 (ja) 2016-07-29 2023-07-24 ソニーグループ株式会社 超明色二量体またはポリマー色素およびその調製のための方法
EP3504291B1 (en) 2016-08-29 2020-10-28 Life Technologies Corporation Fluorescent particles
EP3507603B1 (en) 2016-09-01 2024-03-06 Life Technologies Corporation Compositions and methods for enhanced fluorescence
IL250207A0 (en) 2017-01-19 2017-03-30 Augmanity Nano Ltd Origami RNA from ribosomal RNA and methods for its preparation
US11874280B2 (en) 2018-03-19 2024-01-16 Sony Group Corporation Use of divalent metals for enhancement of fluorescent signals
KR102864292B1 (ko) 2018-03-21 2025-09-26 소니그룹주식회사 링커 군을 갖는 중합체성 텐덤 염료
US12006438B2 (en) 2018-06-27 2024-06-11 Sony Group Corporation Polymeric dyes with linker groups comprising deoxyribose
EP3820944A1 (en) 2018-07-13 2021-05-19 Sony Corporation Polymeric dyes having a backbone comprising organophosphate units

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020160411A1 (en) 1999-12-14 2002-10-31 Research Corporation Technologies, Inc. Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same
JP2012515905A (ja) 2009-01-22 2012-07-12 ウニベルジテート ポツダム 多重化ｆｒｅｔ解析により試料中の検体を検出する方法及びキット
JP2016014033A (ja) 2009-02-18 2016-01-28 カーネギー メロン ユニバーシティ 明検出のためのクエンチャー付加デンドリマー色素
US20130309671A1 (en) 2012-05-18 2013-11-21 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Spectro-Temporal Optical Encoding of Information Using a Time-Gated Fluorescence Resonance Energy Transfer (FRET)
US20150293022A1 (en) 2014-04-15 2015-10-15 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Use of Modular Nucleic Acid Scaffolds to Create Nanoscale Energy Harvesting and Focusing Arrays

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Buckhout-White, S. et al.，Assembling programmable FRET-based photonic networks using designer DNA scaffolds，Nat. Commun.，2014年12月11日，Vol. 5, Article No. 5615，pp. 1-16，doi:10.1038/ncomms6615
DIAZ, S. A. et al.，Extending DNA-Based Molecular Photonic Wires with Homogeneous Forster Resonance Energy Transfer，Adv. Optical Mater.，2016年01月07日，Vol. 4，pp. 399-412，doi:10.1002/adom.201500554
Dwyer, C. et al.，DNA Self-Assembled Nanostructures for Resonance Energy Transfer Circuits，Nanophotonic Information Physics，2013年12月08日，pp. 41-65，doi:10.1007/978-3-642-40224-1_2
LaBoda C. et al.，DNA-Enabled Integrated Molecular Systems for Computation and Sensing，Acc. Chem. Res.，2014年05月21日，Vol. 47，pp. 1816-1824，doi:10.1021/ar5000054u
Olejko L. and Bald I.，FRET efficiency and antenna effect in multi-color DNA origami-based light harvesting systems，RSC Advances，2017年05月03日，Vol. 7，pp. 23924-23934，doi:10.1039/c7ra02114c

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