JP7265325B2 - 好塩基球の活性化を検出するための方法 - Google Patents

好塩基球の活性化を検出するための方法 Download PDF

Info

Publication number
JP7265325B2
JP7265325B2 JP2018147570A JP2018147570A JP7265325B2 JP 7265325 B2 JP7265325 B2 JP 7265325B2 JP 2018147570 A JP2018147570 A JP 2018147570A JP 2018147570 A JP2018147570 A JP 2018147570A JP 7265325 B2 JP7265325 B2 JP 7265325B2
Authority
JP
Japan
Prior art keywords
basophils
ligand
shows
chemiluminescence
activated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2018147570A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019032317A (ja
JP2019032317A5 (enExample
Inventor
グリューネ ユリア
セイスマン ヘニング
ヴァイマン アルフ
Original Assignee
ユーロイミューン・メディツィニシェ・ラボルディアグノシュティカ・アクチエンゲゼルシャフト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP17001352.8A external-priority patent/EP3441763A1/de
Application filed by ユーロイミューン・メディツィニシェ・ラボルディアグノシュティカ・アクチエンゲゼルシャフト filed Critical ユーロイミューン・メディツィニシェ・ラボルディアグノシュティカ・アクチエンゲゼルシャフト
Publication of JP2019032317A publication Critical patent/JP2019032317A/ja
Publication of JP2019032317A5 publication Critical patent/JP2019032317A5/ja
Application granted granted Critical
Publication of JP7265325B2 publication Critical patent/JP7265325B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plasma & Fusion (AREA)
  • Ecology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Virology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
JP2018147570A 2017-08-08 2018-08-06 好塩基球の活性化を検出するための方法 Active JP7265325B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP17001352.8A EP3441763A1 (de) 2017-08-08 2017-08-08 Verfahren zum nachweis einer basophilenaktivierung
EP17001352.8 2017-08-08
EP17001979.8 2017-12-05
EP17001979 2017-12-05

Publications (3)

Publication Number Publication Date
JP2019032317A JP2019032317A (ja) 2019-02-28
JP2019032317A5 JP2019032317A5 (enExample) 2023-01-26
JP7265325B2 true JP7265325B2 (ja) 2023-04-26

Family

ID=63041937

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018147570A Active JP7265325B2 (ja) 2017-08-08 2018-08-06 好塩基球の活性化を検出するための方法

Country Status (13)

Country Link
US (1) US11119109B2 (enExample)
EP (1) EP3441765B1 (enExample)
JP (1) JP7265325B2 (enExample)
KR (1) KR102547565B1 (enExample)
CN (1) CN109387636B (enExample)
AU (1) AU2018213977B2 (enExample)
BR (1) BR102018015288A2 (enExample)
CA (1) CA3012989A1 (enExample)
DE (1) DE102018006212A1 (enExample)
ES (1) ES2904354T3 (enExample)
LT (1) LT3441765T (enExample)
PL (1) PL3441765T3 (enExample)
SG (1) SG10201806697RA (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210382070A1 (en) * 2020-06-04 2021-12-09 The Chinese University Of Hong Kong Diagnostic biomarkers for shrimp allergy
CN112630423A (zh) * 2020-12-31 2021-04-09 杭州福德敏生物技术有限公司 一种小麦免疫荧光检测试纸条及应用
KR102497904B1 (ko) * 2021-02-10 2023-02-10 재단법인 아산사회복지재단 세포 원심분리 및 농축을 이용한 면역세포 검출 방법 및 면역세포 검출용 칩

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005509845A (ja) 2001-09-17 2005-04-14 イムメド エス．アール．オー． ある物質に対する過敏症を判定するための、アレルゲンによって誘起された好塩基球の賦活化の測定のための方法およびキット
WO2012044756A2 (en) 2010-10-01 2012-04-05 The Board Of Trustees Of The Leland Stanford Junior University Basophil activation based allergy diagnostic test
WO2012105541A1 (ja) 2011-01-31 2012-08-09 大鵬薬品工業株式会社 新規ヒノキ花粉アレルゲン

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3169833D1 (en) 1980-08-22 1985-05-15 Berthold Lab Prof R Process for performing analytical determinations by means of the chemiluminescent method, and application of this process to immuno assays
US4902613A (en) 1984-05-14 1990-02-20 Becton, Dickinson And Company Lysing agent for analysis of peripheral blood cells
EP0182874B1 (en) 1984-05-31 1993-10-20 Coulter Corporation A reagent system and method for identification, enumeration and examination of classes and subclasses of blood leukocytes
WO1998032014A1 (de) 1997-01-20 1998-07-23 Orpegen Pharma Gmbh Basophilen-degranulationstest
FR2778413B1 (fr) 1998-05-07 2000-08-04 Immunotech Sa Nouveaux reactifs et methode de lyse des erythrocytes
DE10235310B4 (de) 2002-08-01 2012-05-16 Molecular And Clinical Drug Research Verfahren zur Bestimmung allergener Potenz von Produkten
RU2289138C2 (ru) * 2004-12-14 2006-12-10 Научно-исследовательский институт микробиологии Министерства обороны Российской Федерации Способ аллергодиагностики по показателям хемилюминесцентного свечения нейтрофилов
EP2037269B1 (en) * 2007-09-11 2014-04-02 Bühlmann Laboratories AG Allergy test based on flow cytometric analysis
JP2009236798A (ja) 2008-03-28 2009-10-15 Sysmex Corp 好塩基球の分類計数方法
US20100167317A1 (en) * 2008-08-05 2010-07-01 Institut Pasteur Process for enriching basophils in a blood sample
WO2012028167A2 (en) 2010-05-20 2012-03-08 Innohyphen Bv Acridinium ester chemiluminescence upon reductive triggering
US20150299315A1 (en) * 2012-10-22 2015-10-22 Becton, Dickinson And Company Non-b-lineage cells capable of producing antibody
EP3051928B1 (de) 2015-01-29 2019-01-16 Kjellberg-Stiftung Plasmabrenner
CN104677810B (zh) * 2015-01-30 2017-08-22 广东医学院附属医院 嗜碱性粒细胞活化的检测试剂盒及其使用方法
CN104777303B (zh) * 2015-04-29 2017-02-01 何韶衡 一种嗜碱性粒细胞激活、脱颗粒的鉴定方法
HUE047265T2 (hu) 2016-01-25 2020-04-28 Euroimmun Medizinische Labordiagnostika Ag Makadámia allergén
EP3244212A1 (en) 2017-02-15 2017-11-15 Euroimmun Medizinische Labordiagnostika AG An improved assay for the diagnosis of peanut allergy

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005509845A (ja) 2001-09-17 2005-04-14 イムメド エス．アール．オー． ある物質に対する過敏症を判定するための、アレルゲンによって誘起された好塩基球の賦活化の測定のための方法およびキット
WO2012044756A2 (en) 2010-10-01 2012-04-05 The Board Of Trustees Of The Leland Stanford Junior University Basophil activation based allergy diagnostic test
WO2012105541A1 (ja) 2011-01-31 2012-08-09 大鵬薬品工業株式会社 新規ヒノキ花粉アレルゲン

Also Published As

Publication number Publication date
JP2019032317A (ja) 2019-02-28
ES2904354T3 (es) 2022-04-04
US20190049461A1 (en) 2019-02-14
KR20190016446A (ko) 2019-02-18
KR102547565B1 (ko) 2023-06-26
SG10201806697RA (en) 2019-03-28
AU2018213977B2 (en) 2025-02-20
LT3441765T (lt) 2022-01-10
AU2018213977A1 (en) 2019-02-28
US11119109B2 (en) 2021-09-14
DE102018006212A1 (de) 2019-02-14
CN109387636B (zh) 2023-07-04
CA3012989A1 (en) 2019-02-08
PL3441765T3 (pl) 2022-02-14
EP3441765A1 (de) 2019-02-13
EP3441765B1 (de) 2021-10-20
BR102018015288A2 (pt) 2021-11-09
CN109387636A (zh) 2019-02-26

Similar Documents

Publication Publication Date Title
EP2037269B1 (en) Allergy test based on flow cytometric analysis
US11796547B2 (en) Methods of detecting donor-specific antibodies and systems for practicing the same
JP2012510618A (ja) 補体固定抗体の検出のための方法および組成物
JP2011514517A (ja) 環状シトルリン化ペプチドに対する抗体のアッセイ方法
JP7265325B2 (ja) 好塩基球の活性化を検出するための方法
KR20020021774A (ko) 전염성 해면체성 뇌병증 진단 방법
US20210247397A1 (en) Complement c4d assay
US20110269162A1 (en) Ubiquitin proteasome system profiling for diagnosis of chronic liver disease
JP2019032317A5 (enExample)
US20140302526A1 (en) Zap-70 detection in chronic lymphocytic leukemia
Kaur et al. Pull Down Assay-Based Protein Analysis
EP3441763A1 (de) Verfahren zum nachweis einer basophilenaktivierung
FR2765341A1 (fr) Methode pour l'analyse de l'activation des basophiles humains par mesure de l'expression membranaire du marqueur cd63
Kim et al. Common in vitro tests for allergy and immunology.
Alzahrani Assessing basophil activation in allergic disease by the measurement of the unique marker basogranulin: Release into cell supernatants and biological fluids, and alterations in intracellular and membrane expression
CN117825719A (zh) 用于嗜酸性肉芽肿性多血管炎诊断的蛋白质组合物
EP2553465A1 (en) Method to detect tissue degradation leading to inflammation
EP2960654A1 (en) A method for detecting EP3 antibodies
JP2003254966A (ja) 抗カルパスタチン抗体の測定法及び測定キット

Legal Events

Date Code Title Description
RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20181121

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20181203

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210804

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20220810

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220819

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20221109

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20230117

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20230404

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20230414

R150 Certificate of patent or registration of utility model

Ref document number: 7265325

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150