SG10201806697RA - Method for detecting basophil activation - Google Patents
Method for detecting basophil activationInfo
- Publication number
- SG10201806697RA SG10201806697RA SG10201806697RA SG10201806697RA SG10201806697RA SG 10201806697R A SG10201806697R A SG 10201806697RA SG 10201806697R A SG10201806697R A SG 10201806697RA SG 10201806697R A SG10201806697R A SG 10201806697RA SG 10201806697R A SG10201806697R A SG 10201806697RA
- Authority
- SG
- Singapore
- Prior art keywords
- basophils
- allergen
- agent
- ligand
- activation
- Prior art date
Links
- 210000003651 basophil Anatomy 0.000 title abstract 11
- 230000004913 activation Effects 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 239000013566 allergen Substances 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- 239000003446 ligand Substances 0.000 abstract 4
- 210000004369 blood Anatomy 0.000 abstract 3
- 239000008280 blood Substances 0.000 abstract 3
- 239000003550 marker Substances 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- GRYSXUXXBDSYRT-WOUKDFQISA-N (2r,3r,4r,5r)-2-(hydroxymethyl)-4-methoxy-5-[6-(methylamino)purin-9-yl]oxolan-3-ol Chemical compound C1=NC=2C(NC)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1OC GRYSXUXXBDSYRT-WOUKDFQISA-N 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000003743 erythrocyte Anatomy 0.000 abstract 1
- 230000002934 lysing effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plasma & Fusion (AREA)
- Ecology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physiology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Virology (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17001352.8A EP3441763A1 (de) | 2017-08-08 | 2017-08-08 | Verfahren zum nachweis einer basophilenaktivierung |
| EP17001979 | 2017-12-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201806697RA true SG10201806697RA (en) | 2019-03-28 |
Family
ID=63041937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201806697RA SG10201806697RA (en) | 2017-08-08 | 2018-08-06 | Method for detecting basophil activation |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11119109B2 (enExample) |
| EP (1) | EP3441765B1 (enExample) |
| JP (1) | JP7265325B2 (enExample) |
| KR (1) | KR102547565B1 (enExample) |
| CN (1) | CN109387636B (enExample) |
| AU (1) | AU2018213977B2 (enExample) |
| BR (1) | BR102018015288A2 (enExample) |
| CA (1) | CA3012989A1 (enExample) |
| DE (1) | DE102018006212A1 (enExample) |
| ES (1) | ES2904354T3 (enExample) |
| LT (1) | LT3441765T (enExample) |
| PL (1) | PL3441765T3 (enExample) |
| SG (1) | SG10201806697RA (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210382070A1 (en) * | 2020-06-04 | 2021-12-09 | The Chinese University Of Hong Kong | Diagnostic biomarkers for shrimp allergy |
| CN112630423A (zh) * | 2020-12-31 | 2021-04-09 | 杭州福德敏生物技术有限公司 | 一种小麦免疫荧光检测试纸条及应用 |
| KR102497904B1 (ko) * | 2021-02-10 | 2023-02-10 | 재단법인 아산사회복지재단 | 세포 원심분리 및 농축을 이용한 면역세포 검출 방법 및 면역세포 검출용 칩 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3169833D1 (en) | 1980-08-22 | 1985-05-15 | Berthold Lab Prof R | Process for performing analytical determinations by means of the chemiluminescent method, and application of this process to immuno assays |
| US4902613A (en) | 1984-05-14 | 1990-02-20 | Becton, Dickinson And Company | Lysing agent for analysis of peripheral blood cells |
| EP0182874B1 (en) | 1984-05-31 | 1993-10-20 | Coulter Corporation | A reagent system and method for identification, enumeration and examination of classes and subclasses of blood leukocytes |
| WO1998032014A1 (de) | 1997-01-20 | 1998-07-23 | Orpegen Pharma Gmbh | Basophilen-degranulationstest |
| FR2778413B1 (fr) | 1998-05-07 | 2000-08-04 | Immunotech Sa | Nouveaux reactifs et methode de lyse des erythrocytes |
| CZ292686B6 (cs) * | 2001-09-17 | 2003-11-12 | Imumed S. R. O. | Způsob měření aktivace basofilů po stimulaci alergenem pro stanovení přecitlivělosti na tento alergen a příslušný kit |
| DE10235310B4 (de) | 2002-08-01 | 2012-05-16 | Molecular And Clinical Drug Research | Verfahren zur Bestimmung allergener Potenz von Produkten |
| RU2289138C2 (ru) * | 2004-12-14 | 2006-12-10 | Научно-исследовательский институт микробиологии Министерства обороны Российской Федерации | Способ аллергодиагностики по показателям хемилюминесцентного свечения нейтрофилов |
| EP2037269B1 (en) * | 2007-09-11 | 2014-04-02 | Bühlmann Laboratories AG | Allergy test based on flow cytometric analysis |
| JP2009236798A (ja) | 2008-03-28 | 2009-10-15 | Sysmex Corp | 好塩基球の分類計数方法 |
| US20100167317A1 (en) * | 2008-08-05 | 2010-07-01 | Institut Pasteur | Process for enriching basophils in a blood sample |
| WO2012028167A2 (en) | 2010-05-20 | 2012-03-08 | Innohyphen Bv | Acridinium ester chemiluminescence upon reductive triggering |
| US20120083007A1 (en) | 2010-10-01 | 2012-04-05 | Nadeau Kari C | Basophil Activation Based Allergy Diagnostic Test |
| WO2012105541A1 (ja) | 2011-01-31 | 2012-08-09 | 大鵬薬品工業株式会社 | 新規ヒノキ花粉アレルゲン |
| US20150299315A1 (en) * | 2012-10-22 | 2015-10-22 | Becton, Dickinson And Company | Non-b-lineage cells capable of producing antibody |
| EP3051928B1 (de) | 2015-01-29 | 2019-01-16 | Kjellberg-Stiftung | Plasmabrenner |
| CN104677810B (zh) * | 2015-01-30 | 2017-08-22 | 广东医学院附属医院 | 嗜碱性粒细胞活化的检测试剂盒及其使用方法 |
| CN104777303B (zh) * | 2015-04-29 | 2017-02-01 | 何韶衡 | 一种嗜碱性粒细胞激活、脱颗粒的鉴定方法 |
| HUE047265T2 (hu) | 2016-01-25 | 2020-04-28 | Euroimmun Medizinische Labordiagnostika Ag | Makadámia allergén |
| EP3244212A1 (en) | 2017-02-15 | 2017-11-15 | Euroimmun Medizinische Labordiagnostika AG | An improved assay for the diagnosis of peanut allergy |
-
2018
- 2018-07-26 BR BR102018015288-2A patent/BR102018015288A2/pt unknown
- 2018-08-01 CA CA3012989A patent/CA3012989A1/en active Pending
- 2018-08-06 KR KR1020180091151A patent/KR102547565B1/ko active Active
- 2018-08-06 US US16/055,936 patent/US11119109B2/en active Active
- 2018-08-06 JP JP2018147570A patent/JP7265325B2/ja active Active
- 2018-08-06 AU AU2018213977A patent/AU2018213977B2/en active Active
- 2018-08-06 SG SG10201806697RA patent/SG10201806697RA/en unknown
- 2018-08-07 EP EP18187647.5A patent/EP3441765B1/de active Active
- 2018-08-07 DE DE102018006212.1A patent/DE102018006212A1/de not_active Withdrawn
- 2018-08-07 LT LTEP18187647.5T patent/LT3441765T/lt unknown
- 2018-08-07 PL PL18187647T patent/PL3441765T3/pl unknown
- 2018-08-07 ES ES18187647T patent/ES2904354T3/es active Active
- 2018-08-08 CN CN201810893515.7A patent/CN109387636B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019032317A (ja) | 2019-02-28 |
| ES2904354T3 (es) | 2022-04-04 |
| US20190049461A1 (en) | 2019-02-14 |
| KR20190016446A (ko) | 2019-02-18 |
| KR102547565B1 (ko) | 2023-06-26 |
| AU2018213977B2 (en) | 2025-02-20 |
| JP7265325B2 (ja) | 2023-04-26 |
| LT3441765T (lt) | 2022-01-10 |
| AU2018213977A1 (en) | 2019-02-28 |
| US11119109B2 (en) | 2021-09-14 |
| DE102018006212A1 (de) | 2019-02-14 |
| CN109387636B (zh) | 2023-07-04 |
| CA3012989A1 (en) | 2019-02-08 |
| PL3441765T3 (pl) | 2022-02-14 |
| EP3441765A1 (de) | 2019-02-13 |
| EP3441765B1 (de) | 2021-10-20 |
| BR102018015288A2 (pt) | 2021-11-09 |
| CN109387636A (zh) | 2019-02-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2021009726A (es) | Metodos y sistemas para determinar un estado relacionado con el embarazo de un sujeto. | |
| WO2008082979A3 (en) | Diagnostic test for the detection of a molecule or drug in whole blood | |
| WO2007002480A3 (en) | Systems and methods including self-contained cartridges with detection systems and fluid delivery systems | |
| MX2009013388A (es) | Analisis multiple de muestras de sangre. | |
| MX2015013596A (es) | Metodos, dispositivos y sistemas para analisis de muestras. | |
| DE60219207D1 (de) | Diagnostisches testverfahren | |
| JP2012513773A5 (enExample) | ||
| WO2005086647A3 (en) | Immuno-pcr method for the detection of a biomolecule in a test sample | |
| SG10201906750XA (en) | Assays for detecting the presence or amount of an anti-drug antibody | |
| ATE538386T1 (de) | Nachweis von krebs anhand von erhöhten bcl-2- konzentrationen | |
| EP4524571A3 (en) | Assay for jc virus antibodies | |
| IL172997A (en) | Device and method for simultaneous carrying out of blood group determination, serum cross-check and antibody detection test | |
| MY162697A (en) | Methods, devices and kits for detecting or monitoring acute kidney injury | |
| GB2449045A (en) | Purification method and kits | |
| WO2010107654A3 (en) | Split flow device for analyses of specific-binding partners | |
| PE20141450A1 (es) | Ensayo de lisiloxidasa-homologo 2 y metodos de uso del mismo | |
| NZ609824A (en) | Immunochromatography devices, methods and kits | |
| SG10201806697RA (en) | Method for detecting basophil activation | |
| IN2015DN04062A (enExample) | ||
| MY157955A (en) | Detection of a target antigen irrespective of the presence or absence of a corresponding therapeutic antibody | |
| BR112018071867A2 (pt) | método de uso de citômetro de fluxo em um sistema automático de manipulação de fluidos, método de uso de citômetro de fluxo para testar amostras de fluido corporal, método de compensação de imprecisões da enumeração por citômetro de fluxo de partículas de interesse em amostras de fluido, e sistema de teste automático de amostras de fluido corporal | |
| MX2021010738A (es) | Dispositivo de analisis de sangre para deteccion de hemolisis. | |
| WO2018115247A8 (en) | Method for identifying a reagent during a process in an analysis system | |
| JP2019032317A5 (enExample) | ||
| SG164389A1 (en) | Detection of a therapeutic antibody in an experimental animal |