JP7258870B2 - 歯周炎ワクチンおよび関連組成物ならびに使用方法 - Google Patents

歯周炎ワクチンおよび関連組成物ならびに使用方法 Download PDF

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JP7258870B2
JP7258870B2 JP2020520602A JP2020520602A JP7258870B2 JP 7258870 B2 JP7258870 B2 JP 7258870B2 JP 2020520602 A JP2020520602 A JP 2020520602A JP 2020520602 A JP2020520602 A JP 2020520602A JP 7258870 B2 JP7258870 B2 JP 7258870B2
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mfa1
sequence
antigen sequence
polypeptide
immunogenic composition
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Japanese (ja)
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JP2020536925A (ja
JP2020536925A5 (https=
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ジェファリー・フェアマン
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Vaxcyte Inc
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Vaxcyte Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0216Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
JP2020520602A 2017-10-12 2018-10-11 歯周炎ワクチンおよび関連組成物ならびに使用方法 Active JP7258870B2 (ja)

Priority Applications (1)

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JP2023061241A JP2023098935A (ja) 2017-10-12 2023-04-05 歯周炎ワクチンおよび関連組成物ならびに使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762571582P 2017-10-12 2017-10-12
US62/571,582 2017-10-12
PCT/US2018/055496 WO2019075260A1 (en) 2017-10-12 2018-10-11 VACCINE AGAINST PERIODONTITIS AND ASSOCIATED COMPOSITIONS AND METHOD OF USE

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JP2023061241A Division JP2023098935A (ja) 2017-10-12 2023-04-05 歯周炎ワクチンおよび関連組成物ならびに使用方法

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JP2020536925A JP2020536925A (ja) 2020-12-17
JP2020536925A5 JP2020536925A5 (https=) 2021-11-25
JP7258870B2 true JP7258870B2 (ja) 2023-04-17

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JP2020520602A Active JP7258870B2 (ja) 2017-10-12 2018-10-11 歯周炎ワクチンおよび関連組成物ならびに使用方法
JP2023061241A Pending JP2023098935A (ja) 2017-10-12 2023-04-05 歯周炎ワクチンおよび関連組成物ならびに使用方法

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JP2023061241A Pending JP2023098935A (ja) 2017-10-12 2023-04-05 歯周炎ワクチンおよび関連組成物ならびに使用方法

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Country Link
US (3) US10835590B2 (https=)
EP (1) EP3694547A1 (https=)
JP (2) JP7258870B2 (https=)
KR (2) KR20230066660A (https=)
CN (1) CN111225684A (https=)
AU (1) AU2018347511A1 (https=)
CA (1) CA3078630A1 (https=)
EA (1) EA202090908A1 (https=)
IL (1) IL273690A (https=)
MA (1) MA50363A (https=)
MX (1) MX2020003810A (https=)
PH (1) PH12020550239A1 (https=)
SG (1) SG11202003147XA (https=)
WO (1) WO2019075260A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023098935A (ja) * 2017-10-12 2023-07-11 バックスサイト・インコーポレイテッド 歯周炎ワクチンおよび関連組成物ならびに使用方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025019900A1 (en) * 2023-07-26 2025-01-30 Denteric Pty Ltd Chimeric protein vaccine
CN116751292B (zh) * 2023-07-31 2024-05-14 河南大学 牙龈卟啉单胞菌Mfa1单克隆抗体及其应用

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JPS59128338A (ja) 1982-12-08 1984-07-24 Kitasato Inst:The 歯周炎予防用ワクチン及びその製法
WO1994028014A2 (en) 1993-05-28 1994-12-08 Chiron Corporation Peptide inhibitors of urokinase receptor activity
AUPN627595A0 (en) * 1995-10-30 1995-11-23 University Of Melbourne, The Diagnostics and treatments of periodontal disease
CA2249994A1 (en) * 1996-03-22 1997-09-25 University Of Georgia Research Foundation, Inc. Immunogenic compositions comprising porphyromonas gingivalis peptides and methods
US6833262B1 (en) 1999-04-21 2004-12-21 University Of Georgia Research Foundation, Inc. Polypeptide having amidolytic activity for a serpin
AUPQ065299A0 (en) 1999-05-28 1999-06-24 University Of Sydney, The A method of prophylaxis and treatment and agents useful for same
AUPQ485999A0 (en) * 1999-12-24 2000-02-03 Csl Limited P. gingivalis antigenic composition
US7378101B2 (en) 2001-12-21 2008-05-27 Pfizer, Inc. Vaccine for periodontal disease
GB0411150D0 (en) 2004-05-19 2004-06-23 Queen Mary & Westfield College Vaccine
CN102712693A (zh) 2009-08-02 2012-10-03 圣诺菲·帕斯图尔有限公司 牙龈卟啉单胞菌多肽
WO2011097688A1 (en) 2010-02-12 2011-08-18 The University Of Sydney Protein domains and uses therefor
US9040253B2 (en) 2010-04-14 2015-05-26 Sutro Biopharma, Inc. Method for enhancing recombinant protein production by cell-free protein expression system
PL2906592T3 (pl) 2012-10-12 2019-07-31 Sutro Biopharma, Inc. Proteolityczna inaktywacja wybranych białek w ekstraktach bakteryjnych dla ulepszonej ekspresji
EP3365027B1 (en) * 2015-10-14 2022-03-30 Research Institute at Nationwide Children's Hospital Hu specific antibodies and their use in inhibiting biofilm
SG11202003147XA (en) 2017-10-12 2020-05-28 Vaxcyte Inc Periodontitis vaccine and related compositions and method of use

Non-Patent Citations (4)

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Title
FRAZER L T,VACCINE,NL,ELSEVIER,2006年10月30日,VOL:24, NR:42-43,PAGE(S):6542 - 6554,http://dx.doi.org/10.1016/j.vaccine.2006.06.013
GIBSON FRANK C III,INFECTION AND IMMUNITY,米国,AMERICAN SOCIETY FOR MICROBIOLOGY,2001年12月,VOL:69, NR:12,PAGE(S):7959 - 7963,http://dx.doi.org/10.1128/IAI.69.12.7959-7963.2001
NAKAO RYOMA,VACCINE,NL,ELSEVIER,2016年07月25日,VOL:34, NR:38,PAGE(S):4626 - 4634,http://dx.doi.org/10.1016/j.vaccine.2016.06.016
RYOMA NAKAO,OUTER MEMBRANE VESICLES OF PORPHYROMONAS GINGIVALIS ELICIT A MUCOSAL IMMUNE RESPONSE,PLOS ONE,2011年10月14日,VOL:6, NR:10,,PAGE(S):E26163/1-7,http://dx.doi.org/10.1371/journal.pone.0026163

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023098935A (ja) * 2017-10-12 2023-07-11 バックスサイト・インコーポレイテッド 歯周炎ワクチンおよび関連組成物ならびに使用方法

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Publication number Publication date
US20240226259A9 (en) 2024-07-11
US20210361756A1 (en) 2021-11-25
US20190192645A1 (en) 2019-06-27
US10835590B2 (en) 2020-11-17
PH12020550239A1 (en) 2021-02-15
US12121575B2 (en) 2024-10-22
BR112020006500A2 (pt) 2020-10-13
KR20230066660A (ko) 2023-05-16
US11701414B2 (en) 2023-07-18
AU2018347511A1 (en) 2020-05-21
US20240131134A1 (en) 2024-04-25
JP2020536925A (ja) 2020-12-17
SG11202003147XA (en) 2020-05-28
WO2019075260A1 (en) 2019-04-18
CA3078630A1 (en) 2019-04-18
KR20200070302A (ko) 2020-06-17
CN111225684A (zh) 2020-06-02
MX2020003810A (es) 2020-08-13
JP2023098935A (ja) 2023-07-11
EA202090908A1 (ru) 2020-10-29
MA50363A (fr) 2020-08-19
AU2018347511A8 (en) 2020-06-11
KR102530966B1 (ko) 2023-05-15
IL273690A (en) 2020-05-31
EP3694547A1 (en) 2020-08-19

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