JP7258870B2 - 歯周炎ワクチンおよび関連組成物ならびに使用方法 - Google Patents

歯周炎ワクチンおよび関連組成物ならびに使用方法 Download PDF

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JP7258870B2
JP7258870B2 JP2020520602A JP2020520602A JP7258870B2 JP 7258870 B2 JP7258870 B2 JP 7258870B2 JP 2020520602 A JP2020520602 A JP 2020520602A JP 2020520602 A JP2020520602 A JP 2020520602A JP 7258870 B2 JP7258870 B2 JP 7258870B2
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mfa1
sequence
antigen sequence
polypeptide
immunogenic composition
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JP2020536925A5 (enExample
JP2020536925A (ja
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ジェファリー・フェアマン
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Vaxcyte Inc
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Vaxcyte Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0216Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
JP2020520602A 2017-10-12 2018-10-11 歯周炎ワクチンおよび関連組成物ならびに使用方法 Active JP7258870B2 (ja)

Priority Applications (1)

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JP2023061241A JP2023098935A (ja) 2017-10-12 2023-04-05 歯周炎ワクチンおよび関連組成物ならびに使用方法

Applications Claiming Priority (3)

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US201762571582P 2017-10-12 2017-10-12
US62/571,582 2017-10-12
PCT/US2018/055496 WO2019075260A1 (en) 2017-10-12 2018-10-11 VACCINE AGAINST PERIODONTITIS AND ASSOCIATED COMPOSITIONS AND METHOD OF USE

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JP2023061241A Division JP2023098935A (ja) 2017-10-12 2023-04-05 歯周炎ワクチンおよび関連組成物ならびに使用方法

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JP2020536925A JP2020536925A (ja) 2020-12-17
JP2020536925A5 JP2020536925A5 (enExample) 2021-11-25
JP7258870B2 true JP7258870B2 (ja) 2023-04-17

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JP2020520602A Active JP7258870B2 (ja) 2017-10-12 2018-10-11 歯周炎ワクチンおよび関連組成物ならびに使用方法
JP2023061241A Pending JP2023098935A (ja) 2017-10-12 2023-04-05 歯周炎ワクチンおよび関連組成物ならびに使用方法

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US (3) US10835590B2 (enExample)
EP (1) EP3694547A1 (enExample)
JP (2) JP7258870B2 (enExample)
KR (2) KR102530966B1 (enExample)
CN (1) CN111225684A (enExample)
AU (1) AU2018347511A1 (enExample)
CA (1) CA3078630A1 (enExample)
EA (1) EA202090908A1 (enExample)
IL (1) IL273690A (enExample)
MA (1) MA50363A (enExample)
MX (1) MX2020003810A (enExample)
PH (1) PH12020550239A1 (enExample)
SG (1) SG11202003147XA (enExample)
WO (1) WO2019075260A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023098935A (ja) * 2017-10-12 2023-07-11 バックスサイト・インコーポレイテッド 歯周炎ワクチンおよび関連組成物ならびに使用方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025019900A1 (en) * 2023-07-26 2025-01-30 Denteric Pty Ltd Chimeric protein vaccine
CN116751292B (zh) * 2023-07-31 2024-05-14 河南大学 牙龈卟啉单胞菌Mfa1单克隆抗体及其应用

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JPS59128338A (ja) 1982-12-08 1984-07-24 Kitasato Inst:The 歯周炎予防用ワクチン及びその製法
FI955720A0 (fi) 1993-05-28 1995-11-27 Chiron Corp Urokinaasireseptoriaktiivisuuden peptidi-inhibiittoreita
AUPN627595A0 (en) * 1995-10-30 1995-11-23 University Of Melbourne, The Diagnostics and treatments of periodontal disease
JP2000507245A (ja) 1996-03-22 2000-06-13 ユニバーシティー オブ ジョージア リサーチ ファウンデーション,インコーポレイテッド Porphyromonas gingivalisペプチドを含む免疫原性組成物および方法
US6833262B1 (en) 1999-04-21 2004-12-21 University Of Georgia Research Foundation, Inc. Polypeptide having amidolytic activity for a serpin
AUPQ065299A0 (en) 1999-05-28 1999-06-24 University Of Sydney, The A method of prophylaxis and treatment and agents useful for same
AUPQ485999A0 (en) * 1999-12-24 2000-02-03 Csl Limited P. gingivalis antigenic composition
US7378101B2 (en) 2001-12-21 2008-05-27 Pfizer, Inc. Vaccine for periodontal disease
GB0411150D0 (en) 2004-05-19 2004-06-23 Queen Mary & Westfield College Vaccine
US9366673B2 (en) 2009-08-02 2016-06-14 Sanofi Pasteur Limited Porphyromonas gingivalis polypeptides
EP2533794A4 (en) 2010-02-12 2014-04-23 Univ Sydney PROTEINDOMAINS AND USES THEREOF
US9040253B2 (en) 2010-04-14 2015-05-26 Sutro Biopharma, Inc. Method for enhancing recombinant protein production by cell-free protein expression system
AU2013329464C1 (en) 2012-10-12 2018-02-15 Sutro Biopharma, Inc. Proteolytic inactivation of select proteins in bacterial extracts for improved expression
WO2017066719A2 (en) * 2015-10-14 2017-04-20 Research Institute At Nationwide Children's Hospital Hu specific interfering agents
EA202090908A1 (ru) 2017-10-12 2020-10-29 Ваксайт, Инк. Вакцина и связанные композиции для лечения пародонтита и способ применения

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Title
FRAZER L T,VACCINE,NL,ELSEVIER,2006年10月30日,VOL:24, NR:42-43,PAGE(S):6542 - 6554,http://dx.doi.org/10.1016/j.vaccine.2006.06.013
GIBSON FRANK C III,INFECTION AND IMMUNITY,米国,AMERICAN SOCIETY FOR MICROBIOLOGY,2001年12月,VOL:69, NR:12,PAGE(S):7959 - 7963,http://dx.doi.org/10.1128/IAI.69.12.7959-7963.2001
NAKAO RYOMA,VACCINE,NL,ELSEVIER,2016年07月25日,VOL:34, NR:38,PAGE(S):4626 - 4634,http://dx.doi.org/10.1016/j.vaccine.2016.06.016
RYOMA NAKAO,OUTER MEMBRANE VESICLES OF PORPHYROMONAS GINGIVALIS ELICIT A MUCOSAL IMMUNE RESPONSE,PLOS ONE,2011年10月14日,VOL:6, NR:10,,PAGE(S):E26163/1-7,http://dx.doi.org/10.1371/journal.pone.0026163

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023098935A (ja) * 2017-10-12 2023-07-11 バックスサイト・インコーポレイテッド 歯周炎ワクチンおよび関連組成物ならびに使用方法

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Publication number Publication date
KR20200070302A (ko) 2020-06-17
US12121575B2 (en) 2024-10-22
KR102530966B1 (ko) 2023-05-15
EP3694547A1 (en) 2020-08-19
WO2019075260A1 (en) 2019-04-18
KR20230066660A (ko) 2023-05-16
CN111225684A (zh) 2020-06-02
BR112020006500A2 (pt) 2020-10-13
US20210361756A1 (en) 2021-11-25
US11701414B2 (en) 2023-07-18
CA3078630A1 (en) 2019-04-18
US20240131134A1 (en) 2024-04-25
MA50363A (fr) 2020-08-19
US20190192645A1 (en) 2019-06-27
MX2020003810A (es) 2020-08-13
US10835590B2 (en) 2020-11-17
EA202090908A1 (ru) 2020-10-29
SG11202003147XA (en) 2020-05-28
JP2023098935A (ja) 2023-07-11
JP2020536925A (ja) 2020-12-17
PH12020550239A1 (en) 2021-02-15
AU2018347511A8 (en) 2020-06-11
AU2018347511A1 (en) 2020-05-21
IL273690A (en) 2020-05-31
US20240226259A9 (en) 2024-07-11

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