CA3078630A1 - Periodontitis vaccine and related compositions and method of use - Google Patents

Periodontitis vaccine and related compositions and method of use Download PDF

Info

Publication number
CA3078630A1
CA3078630A1 CA3078630A CA3078630A CA3078630A1 CA 3078630 A1 CA3078630 A1 CA 3078630A1 CA 3078630 A CA3078630 A CA 3078630A CA 3078630 A CA3078630 A CA 3078630A CA 3078630 A1 CA3078630 A1 CA 3078630A1
Authority
CA
Canada
Prior art keywords
sequence
amino acid
acid sequence
seq
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3078630A
Other languages
English (en)
French (fr)
Inventor
Jeffery Fairman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vaxcyte Inc
Original Assignee
Sutrovax Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sutrovax Inc filed Critical Sutrovax Inc
Publication of CA3078630A1 publication Critical patent/CA3078630A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0216Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CA3078630A 2017-10-12 2018-10-11 Periodontitis vaccine and related compositions and method of use Pending CA3078630A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762571582P 2017-10-12 2017-10-12
US62/571,582 2017-10-12
PCT/US2018/055496 WO2019075260A1 (en) 2017-10-12 2018-10-11 VACCINE AGAINST PERIODONTITIS AND ASSOCIATED COMPOSITIONS AND METHOD OF USE

Publications (1)

Publication Number Publication Date
CA3078630A1 true CA3078630A1 (en) 2019-04-18

Family

ID=64110091

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3078630A Pending CA3078630A1 (en) 2017-10-12 2018-10-11 Periodontitis vaccine and related compositions and method of use

Country Status (14)

Country Link
US (3) US10835590B2 (enExample)
EP (1) EP3694547A1 (enExample)
JP (2) JP7258870B2 (enExample)
KR (2) KR102530966B1 (enExample)
CN (1) CN111225684A (enExample)
AU (1) AU2018347511A1 (enExample)
CA (1) CA3078630A1 (enExample)
EA (1) EA202090908A1 (enExample)
IL (1) IL273690A (enExample)
MA (1) MA50363A (enExample)
MX (1) MX2020003810A (enExample)
PH (1) PH12020550239A1 (enExample)
SG (1) SG11202003147XA (enExample)
WO (1) WO2019075260A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020003810A (es) * 2017-10-12 2020-08-13 Vaxcyte Inc Vacuna contra la periodontitis y composiciones relacionadas y metodos de uso.
WO2025019900A1 (en) * 2023-07-26 2025-01-30 Denteric Pty Ltd Chimeric protein vaccine
CN116751292B (zh) * 2023-07-31 2024-05-14 河南大学 牙龈卟啉单胞菌Mfa1单克隆抗体及其应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59128338A (ja) 1982-12-08 1984-07-24 Kitasato Inst:The 歯周炎予防用ワクチン及びその製法
ATE182336T1 (de) 1993-05-28 1999-08-15 Chiron Corp Peptidinhibitoren der urokinaserezeptor-aktivität
AUPN627595A0 (en) 1995-10-30 1995-11-23 University Of Melbourne, The Diagnostics and treatments of periodontal disease
AU742668B2 (en) 1996-03-22 2002-01-10 Morehouse School Of Medicine Immunogenic compositions comprising porphyromonas gingivalis peptides and methods
US6833262B1 (en) 1999-04-21 2004-12-21 University Of Georgia Research Foundation, Inc. Polypeptide having amidolytic activity for a serpin
AUPQ065299A0 (en) 1999-05-28 1999-06-24 University Of Sydney, The A method of prophylaxis and treatment and agents useful for same
AUPQ485999A0 (en) 1999-12-24 2000-02-03 Csl Limited P. gingivalis antigenic composition
US7378101B2 (en) 2001-12-21 2008-05-27 Pfizer, Inc. Vaccine for periodontal disease
GB0411150D0 (en) 2004-05-19 2004-06-23 Queen Mary & Westfield College Vaccine
BR112012002429A2 (pt) 2009-08-02 2016-11-08 Sanofi Pasteur Ltd polipeptídeos de porphyromonas gingivalis
AU2011214908A1 (en) 2010-02-12 2012-09-20 Sydney West Area Health Services (Swahs) Protein domains and uses therefor
US9040253B2 (en) 2010-04-14 2015-05-26 Sutro Biopharma, Inc. Method for enhancing recombinant protein production by cell-free protein expression system
CA2887355C (en) 2012-10-12 2023-03-07 Sutro Biopharma, Inc. Proteolytic inactivation of select proteins in bacterial extracts for improved expression
WO2017066719A2 (en) * 2015-10-14 2017-04-20 Research Institute At Nationwide Children's Hospital Hu specific interfering agents
MX2020003810A (es) 2017-10-12 2020-08-13 Vaxcyte Inc Vacuna contra la periodontitis y composiciones relacionadas y metodos de uso.

Also Published As

Publication number Publication date
US20210361756A1 (en) 2021-11-25
SG11202003147XA (en) 2020-05-28
PH12020550239A1 (en) 2021-02-15
IL273690A (en) 2020-05-31
JP2020536925A (ja) 2020-12-17
EP3694547A1 (en) 2020-08-19
JP2023098935A (ja) 2023-07-11
BR112020006500A2 (pt) 2020-10-13
US20240226259A9 (en) 2024-07-11
EA202090908A1 (ru) 2020-10-29
MA50363A (fr) 2020-08-19
KR20200070302A (ko) 2020-06-17
US11701414B2 (en) 2023-07-18
US12121575B2 (en) 2024-10-22
CN111225684A (zh) 2020-06-02
JP7258870B2 (ja) 2023-04-17
WO2019075260A1 (en) 2019-04-18
KR102530966B1 (ko) 2023-05-15
AU2018347511A1 (en) 2020-05-21
US20240131134A1 (en) 2024-04-25
US10835590B2 (en) 2020-11-17
US20190192645A1 (en) 2019-06-27
MX2020003810A (es) 2020-08-13
AU2018347511A8 (en) 2020-06-11
KR20230066660A (ko) 2023-05-16

Similar Documents

Publication Publication Date Title
US12121575B2 (en) Periodontitis vaccine and related compositions and methods of use
KR100517114B1 (ko) 폴리감마글루탐산을 함유하는 면역보강제 조성물
CN102203121A (zh) 牙龈卟啉单胞菌感染的预防、治疗和诊断
JP2023531059A (ja) 肺炎桿菌o抗原ワクチン
JP2017513849A (ja) A群レンサ球菌ワクチン
AU2009323682A1 (en) Glutamyl tRNA synthetase (GtS) fragments
US9119803B2 (en) Carious tooth vaccine and preparation method
US12280097B2 (en) Optimized cell-free synthesis of invasion plasmid antigen B and related compositions and methods of use
WO2023137522A1 (en) Chimeric polypeptides
US10933126B2 (en) Clostridium difficile immunogenic compositions and methods of use
EA044863B1 (ru) Вакцина и связанные композиции для лечения пародонтита и способ применения
BR112020006500B1 (pt) Composição imunogênica e seus usos, formulação de vacina e usos de um polipeptídeo para fabricação de uma composição imunogênica
FR2809960A1 (fr) Composition adjuvante de la reponse immunitaire comprenant la proteine fha ou un fragment de la proteine fha sous forme libre, et composition immunogene ou vaccinale contenant une telle composition adjuvante
EP0420743B1 (fr) Vaccin protecteur contre l'hémophilose porcine
EA050190B1 (ru) Оптимизированный бесклеточный синтез плазмидного антигена инвазии в и родственные композиции и способы применения
WO2011033319A1 (en) Commensal neisserial stress protein preparations

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20231004