JP7210542B2 - Ctイメージング用のヨウ素化脂肪酸のナノエマルジョン - Google Patents

Ctイメージング用のヨウ素化脂肪酸のナノエマルジョン Download PDF

Info

Publication number
JP7210542B2
JP7210542B2 JP2020506159A JP2020506159A JP7210542B2 JP 7210542 B2 JP7210542 B2 JP 7210542B2 JP 2020506159 A JP2020506159 A JP 2020506159A JP 2020506159 A JP2020506159 A JP 2020506159A JP 7210542 B2 JP7210542 B2 JP 7210542B2
Authority
JP
Japan
Prior art keywords
vivo imaging
contrast agent
iodinated
fatty acids
nanoemulsion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2020506159A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020529441A (ja
JP2020529441A5 (enExample
Inventor
ローレン ヴィネット
アンドレイ バビック
エリック アレマン
Original Assignee
ユニベルシテ ドゥ ジュネーブ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ユニベルシテ ドゥ ジュネーブ filed Critical ユニベルシテ ドゥ ジュネーブ
Publication of JP2020529441A publication Critical patent/JP2020529441A/ja
Publication of JP2020529441A5 publication Critical patent/JP2020529441A5/ja
Application granted granted Critical
Publication of JP7210542B2 publication Critical patent/JP7210542B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461Dispersions, colloids, emulsions or suspensions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Medicinal Preparation (AREA)
JP2020506159A 2017-08-07 2018-07-27 Ctイメージング用のヨウ素化脂肪酸のナノエマルジョン Active JP7210542B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17185185.0 2017-08-07
EP17185185 2017-08-07
PCT/EP2018/070501 WO2019030024A1 (en) 2017-08-07 2018-07-27 NANOEMULSION OF IODIZED FATTY ACIDS FOR COMPUTER-ASSISTED TOMOGRAPHY (CT) IMAGING

Publications (3)

Publication Number Publication Date
JP2020529441A JP2020529441A (ja) 2020-10-08
JP2020529441A5 JP2020529441A5 (enExample) 2021-09-02
JP7210542B2 true JP7210542B2 (ja) 2023-01-23

Family

ID=59564118

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020506159A Active JP7210542B2 (ja) 2017-08-07 2018-07-27 Ctイメージング用のヨウ素化脂肪酸のナノエマルジョン

Country Status (9)

Country Link
US (1) US11654202B2 (enExample)
EP (1) EP3664855A1 (enExample)
JP (1) JP7210542B2 (enExample)
CN (1) CN111194225B (enExample)
AU (1) AU2018314406B2 (enExample)
BR (1) BR112020002619A2 (enExample)
CA (1) CA3072282A1 (enExample)
EA (1) EA202090139A1 (enExample)
WO (1) WO2019030024A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022521371A (ja) * 2019-02-13 2022-04-07 ウニヴァシテ デ ジュネーブ 悪液質を検出するためのct造影剤

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023536358A (ja) * 2020-08-06 2023-08-24 アディポス エスエー Pet-ct撮像方法、その撮像方法における使用のための造影剤および医薬組成物
CN112933246A (zh) * 2020-12-17 2021-06-11 太阳雨林(厦门)生物医药有限公司 一种可显影的油制剂及其制备方法
US20240336552A1 (en) * 2021-08-02 2024-10-10 Microvention, Inc. Compounds
EP4423211A1 (en) 2021-10-28 2024-09-04 Adiposs SA Emulsions, compositions for emulsions, methods for making the same and uses thereof
WO2025079088A1 (en) * 2023-10-11 2025-04-17 Bioroot Exploration India Private Limited A contrast agent for computed tomography and process of preparation thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5258172A (en) * 1983-12-29 1993-11-02 Rubin Daniel L Iodinated aliphatic emulsions for X-ray contrast
DE3785849T2 (de) 1987-06-11 1993-08-26 Kabi Pharmacia Ab Jod enthaltende emulsion.
US5861367A (en) 1993-08-04 1999-01-19 Colgate Palmolive Company Cleaning and disinfecting composition in microemulsion/liquid crystal form comprising aldehyde and mixture of partially esterified, fully esterified and non-esterified polyhydric alcohols
FR2736549B1 (fr) 1995-07-11 1997-10-10 Louis Jung Esters d'acides gras iodes, acides gras iodes et leurs derives, obtenus par iodohydrination faisant intervenir des derives alkylsilyles avec des iodures alcalins et leurs activites pharmacologiques
DE19936727A1 (de) 1999-08-06 2001-02-08 Henkel Kgaa Niotensidbasiertes wäßriges mehrphasiges Reinigungsmittel
US20050079131A1 (en) * 2003-08-08 2005-04-14 Lanza Gregory M. Emulsion particles for imaging and therapy and methods of use thereof
GB0408684D0 (en) 2004-04-19 2004-05-19 Guy S And St Thomas Hospital N Diagnostic method
SG10201505948VA (en) 2004-12-13 2015-09-29 Amylin Pharmaceuticals Llc Pancreatic Polypeptide Family Motifs, Polypeptides And Methods Comprising The Same
ATE496881T1 (de) 2006-02-15 2011-02-15 Ge Healthcare As Kontrastmittel
US20080319315A1 (en) 2007-06-07 2008-12-25 Beth Israel Deaconess Medical Center Method of reducing interferences in positron emission tomography
US20140065067A1 (en) 2010-12-17 2014-03-06 Universite De Strasbourg Radiopaque iodinated products intended for use medical imaging and their methods
KR101263733B1 (ko) 2011-03-22 2013-05-14 한국과학기술연구원 리피오돌을 함유하는 컴퓨터 단층촬영용 혈관 조영제
CN102166365B (zh) 2011-04-25 2012-10-24 东南大学 一种多模态碘油纳米乳造影剂的制备方法
DE102012204378A1 (de) 2012-03-20 2013-09-26 Bernd Schwegmann Gmbh & Co. Kg Reinigungsmittel auf Mikroemulsionsbasis
CN105592862B (zh) 2013-09-30 2020-09-29 贝朗医疗有限公司 肝脏预饱和及其后造影剂的施用
WO2015127347A1 (en) 2014-02-24 2015-08-27 The Regents Of The University Of California Therapeutic hyperbranched polyglycerol encapsulated biomolecules
US10157462B2 (en) 2016-06-27 2018-12-18 University Of Central Florida Research Foundation, Inc. System and method for image-based quantification of white and brown adipose tissue at the whole-body, organ and body-region levels

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
AMERICAN JOURNAL OF ROENTGENOLOGY,1954年,Vol. 72, No. 5,pp. 795-800
Circulation,2018年,Vol. 134, No. suppl_1,Abstract 19281
Eur J Pharm Biopharm.,2013年,Vol. 83,pp. 54-62
Experimental Biology and Medicine,1963年,Vol. 112,pp. 901-903

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022521371A (ja) * 2019-02-13 2022-04-07 ウニヴァシテ デ ジュネーブ 悪液質を検出するためのct造影剤
JP7522744B2 (ja) 2019-02-13 2024-07-25 ウニヴァシテ デ ジュネーブ 悪液質を検出するためのct造影剤

Also Published As

Publication number Publication date
JP2020529441A (ja) 2020-10-08
EP3664855A1 (en) 2020-06-17
EA202090139A1 (ru) 2020-08-06
AU2018314406A1 (en) 2020-02-20
WO2019030024A1 (en) 2019-02-14
CN111194225B (zh) 2023-01-13
CA3072282A1 (en) 2019-02-14
CN111194225A (zh) 2020-05-22
AU2018314406B2 (en) 2024-08-15
BR112020002619A2 (pt) 2020-07-28
US11654202B2 (en) 2023-05-23
US20210330820A1 (en) 2021-10-28

Similar Documents

Publication Publication Date Title
JP7210542B2 (ja) Ctイメージング用のヨウ素化脂肪酸のナノエマルジョン
Zhou et al. Orally administered oleoylethanolamide protects mice from focal cerebral ischemic injury by activating peroxisome proliferator-activated receptor α
JP7522744B2 (ja) 悪液質を検出するためのct造影剤
JP2004522747A (ja) 3,5−ジヨードチロプロピオン酸を用いた慢性心不全および/または高コレステロールの治療方法と、この酸の製造方法
BR112012009859B1 (pt) composição de diagnóstico
US20230284994A1 (en) Pet-ct imaging methods, contrast agents and pharmaceutical compositions for use in said imaging methods
TWI679990B (zh) 肝臟之預飽和以及後續之對比劑的投予
EA043372B1 (ru) Контрастный агент для компьютерной томографии
PT1865990E (pt) Método de tratamento de diabetes de tipo 2
EA045963B1 (ru) Контрастный агент для кт для детекции кахексии
CA3191276A1 (en) Ionic liquid formulations for treating diabetes
WO2000006207A1 (fr) Medicaments a vocation therapeutique permettant un diagnostic en rmn par liaison scalaire
RU2287346C2 (ru) Рентгеноконтрастное средство
Belyanin et al. Study of Organ Uptake of the New Hepatotropic Paramagnetic Contrast Agent, the Mn (II) Complex of 2-[2-Carboxymethyl-(4-Hexadecyloxyphenylcarbamoylmethyl)-Aminoethyl]-Aminoethyl-(4-Hexadecyloxyphenylcarbamoylmethyl)-Aminoacetic Acid (Mn-DTPA-GDOF), In Vivo in Some Experimental Models of Liver Damage in Rats
CN118742299A (zh) 监测患者对视网膜氧化性疾病治疗反应的方法
CN119524167A (zh) 一种低副作用的超声造影剂、制备方法及应用
CN118284421A (zh) 用于治疗胰岛素抗性和/或恢复葡萄糖稳态的生物活性分子
JP2005170807A (ja) 抗体を含むリポソーム

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210720

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210720

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220823

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20221124

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20221128

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20221220

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20230111

R150 Certificate of patent or registration of utility model

Ref document number: 7210542

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150