EA202090139A1 - Контрастный агент для компьютерной томографии - Google Patents

Контрастный агент для компьютерной томографии

Info

Publication number
EA202090139A1
EA202090139A1 EA202090139A EA202090139A EA202090139A1 EA 202090139 A1 EA202090139 A1 EA 202090139A1 EA 202090139 A EA202090139 A EA 202090139A EA 202090139 A EA202090139 A EA 202090139A EA 202090139 A1 EA202090139 A1 EA 202090139A1
Authority
EA
Eurasian Patent Office
Prior art keywords
contrast agent
imaging
computer tomography
iodinated
bat
Prior art date
Application number
EA202090139A
Other languages
English (en)
Inventor
Лоран Вине
Андрей Бабич
Эрик АЛЛЕМАНН
Original Assignee
Юниверсити Оф Женева
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Юниверсити Оф Женева filed Critical Юниверсити Оф Женева
Publication of EA202090139A1 publication Critical patent/EA202090139A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Medicinal Preparation (AREA)

Abstract

Настоящее изобретение относится к йодированному контрастному агенту для КТ, выполненному из производных жирных кислот, для неинвазивной визуализации и количественной оценки бурой и/или бежевой жировой ткани (БЖТ) или для визуализации сердца и/или печени субъекта. Полезно, что этот контрастный агент принимают перорально, что является прорывом в КТ-визуализации. Разрешение изображения, полученного методом КТ, значительно улучшается по сравнению с ПЭТ.
EA202090139A 2017-08-07 2018-07-27 Контрастный агент для компьютерной томографии EA202090139A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17185185 2017-08-07
PCT/EP2018/070501 WO2019030024A1 (en) 2017-08-07 2018-07-27 NANOEMULSION OF IODIZED FATTY ACIDS FOR COMPUTER-ASSISTED TOMOGRAPHY (CT) IMAGING

Publications (1)

Publication Number Publication Date
EA202090139A1 true EA202090139A1 (ru) 2020-08-06

Family

ID=59564118

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202090139A EA202090139A1 (ru) 2017-08-07 2018-07-27 Контрастный агент для компьютерной томографии

Country Status (9)

Country Link
US (1) US11654202B2 (ru)
EP (1) EP3664855A1 (ru)
JP (1) JP7210542B2 (ru)
CN (1) CN111194225B (ru)
AU (1) AU2018314406A1 (ru)
BR (1) BR112020002619A2 (ru)
CA (1) CA3072282A1 (ru)
EA (1) EA202090139A1 (ru)
WO (1) WO2019030024A1 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021014860A8 (pt) * 2019-02-13 2022-06-28 Adiposs SARL Agente de contraste de ct para detecção de caquexia
US20230284994A1 (en) 2020-08-06 2023-09-14 Adiposs Sárl Pet-ct imaging methods, contrast agents and pharmaceutical compositions for use in said imaging methods
CN112933246A (zh) * 2020-12-17 2021-06-11 太阳雨林（厦门）生物医药有限公司 一种可显影的油制剂及其制备方法
WO2023015180A1 (en) * 2021-08-02 2023-02-09 Microvention, Inc. Iodinated fatty acids for medical imaging
WO2023073195A1 (en) 2021-10-28 2023-05-04 Adiposs SA Emulsions, compositions for emulsions, methods for making the same and uses thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5258172A (en) * 1983-12-29 1993-11-02 Rubin Daniel L Iodinated aliphatic emulsions for X-ray contrast
DE3785849T2 (de) 1987-06-11 1993-08-26 Kabi Pharmacia Ab Jod enthaltende emulsion.
US5861367A (en) 1993-08-04 1999-01-19 Colgate Palmolive Company Cleaning and disinfecting composition in microemulsion/liquid crystal form comprising aldehyde and mixture of partially esterified, fully esterified and non-esterified polyhydric alcohols
FR2736549B1 (fr) * 1995-07-11 1997-10-10 Louis Jung Esters d'acides gras iodes, acides gras iodes et leurs derives, obtenus par iodohydrination faisant intervenir des derives alkylsilyles avec des iodures alcalins et leurs activites pharmacologiques
DE19936727A1 (de) 1999-08-06 2001-02-08 Henkel Kgaa Niotensidbasiertes wäßriges mehrphasiges Reinigungsmittel
WO2005014051A1 (en) * 2003-08-08 2005-02-17 Barnes-Jewish Hospital Emulsion particles for imaging and therapy and methods of use thereof
GB0408684D0 (en) 2004-04-19 2004-05-19 Guy S And St Thomas Hospital N Diagnostic method
SI1824876T1 (sl) 2004-12-13 2016-02-29 Amylin Pharmaceuticals, Llc Motivi polipeptidne družine trebušne slinavke, polipeptidi in postopki, ki jih vsebujejo
ATE496881T1 (de) 2006-02-15 2011-02-15 Ge Healthcare As Kontrastmittel
US20080319315A1 (en) 2007-06-07 2008-12-25 Beth Israel Deaconess Medical Center Method of reducing interferences in positron emission tomography
US20140065067A1 (en) 2010-12-17 2014-03-06 Universite De Strasbourg Radiopaque iodinated products intended for use medical imaging and their methods
KR101263733B1 (ko) 2011-03-22 2013-05-14 한국과학기술연구원 리피오돌을 함유하는 컴퓨터 단층촬영용 혈관 조영제
CN102166365B (zh) 2011-04-25 2012-10-24 东南大学 一种多模态碘油纳米乳造影剂的制备方法
DE102012204378A1 (de) 2012-03-20 2013-09-26 Bernd Schwegmann Gmbh & Co. Kg Reinigungsmittel auf Mikroemulsionsbasis
CN105592862B (zh) 2013-09-30 2020-09-29 贝朗医疗有限公司 肝脏预饱和及其后造影剂的施用
US10668161B2 (en) 2014-02-24 2020-06-02 The Regents Of The University Of California Therapeutic hyperbranched polyglycerol encapsulated biomolecules
US10157462B2 (en) 2016-06-27 2018-12-18 University Of Central Florida Research Foundation, Inc. System and method for image-based quantification of white and brown adipose tissue at the whole-body, organ and body-region levels

Also Published As

Publication number Publication date
US11654202B2 (en) 2023-05-23
AU2018314406A1 (en) 2020-02-20
CA3072282A1 (en) 2019-02-14
US20210330820A1 (en) 2021-10-28
WO2019030024A1 (en) 2019-02-14
JP2020529441A (ja) 2020-10-08
CN111194225B (zh) 2023-01-13
JP7210542B2 (ja) 2023-01-23
EP3664855A1 (en) 2020-06-17
CN111194225A (zh) 2020-05-22
BR112020002619A2 (pt) 2020-07-28

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