JP7197494B2 - 抗Ｔａｕナノボディ - Google Patents
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- JP7197494B2 JP7197494B2 JP2019545850A JP2019545850A JP7197494B2 JP 7197494 B2 JP7197494 B2 JP 7197494B2 JP 2019545850 A JP2019545850 A JP 2019545850A JP 2019545850 A JP2019545850 A JP 2019545850A JP 7197494 B2 JP7197494 B2 JP 7197494B2
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| CN112649615A (zh) * | 2020-12-21 | 2021-04-13 | 大连理工大学 | 一种检测不同大小的可溶性Aβ寡聚体的方法及应用 |
| FR3134390B1 (fr) | 2022-04-11 | 2025-10-24 | Univ Grenoble Alpes | Peptide utile pour le transport de molecules au travers de barrieres cellulaires |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2014523742A (ja) | 2011-07-14 | 2014-09-18 | カソリック ウニヴェルシテイト ルーヴェン | リン酸化タウ凝集体に対する抗体 |
| JP2014530597A (ja) | 2011-09-19 | 2014-11-20 | アクソン ニューロサイエンス エスエー | アルツハイマー病におけるタウ媒介性病理のタンパク質ベースの治療および診断 |
| WO2015114538A1 (en) | 2014-01-28 | 2015-08-06 | F. Hoffmann-La Roche Ag | Camelid single-domain antibody directed against phosphorylated tau proteins and methods for producing conjugates thereof |
| JP2015533835A (ja) | 2012-10-12 | 2015-11-26 | アリゾナ ボード オブ リージェンツ フォー アンド オン ビハーフ オブ アリゾナ ステート ユニバーシティ | タウの毒性オリゴマー形態を特異的に認識する抗体ベースの試薬 |
| JP2016104727A (ja) | 2009-08-28 | 2016-06-09 | ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム | タウオリゴマーに結合する抗体 |
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| US4861719A (en) | 1986-04-25 | 1989-08-29 | Fred Hutchinson Cancer Research Center | DNA constructs for retrovirus packaging cell lines |
| US5278056A (en) | 1988-02-05 | 1994-01-11 | The Trustees Of Columbia University In The City Of New York | Retroviral packaging cell lines and process of using same |
| AU6248994A (en) | 1993-02-22 | 1994-09-14 | Rockefeller University, The | Production of high titer helper-free retroviruses by transient transfection |
| FR2712812B1 (fr) | 1993-11-23 | 1996-02-09 | Centre Nat Rech Scient | Composition pour la production de produits thérapeutiques in vivo. |
| AU701643B2 (en) | 1994-09-12 | 1999-02-04 | Schering Aktiengesellschaft | Process for manufacture of a modified collagen-induced platelet aggregation inhibitor pallidipin |
| IL116816A (en) | 1995-01-20 | 2003-05-29 | Rhone Poulenc Rorer Sa | Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| HRP20201064T1 (hr) * | 2013-06-10 | 2021-01-22 | Ipierian, Inc. | Postupci liječenja tauopatije |
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| JP2016104727A (ja) | 2009-08-28 | 2016-06-09 | ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム | タウオリゴマーに結合する抗体 |
| JP2014523742A (ja) | 2011-07-14 | 2014-09-18 | カソリック ウニヴェルシテイト ルーヴェン | リン酸化タウ凝集体に対する抗体 |
| JP2014530597A (ja) | 2011-09-19 | 2014-11-20 | アクソン ニューロサイエンス エスエー | アルツハイマー病におけるタウ媒介性病理のタンパク質ベースの治療および診断 |
| JP2015533835A (ja) | 2012-10-12 | 2015-11-26 | アリゾナ ボード オブ リージェンツ フォー アンド オン ビハーフ オブ アリゾナ ステート ユニバーシティ | タウの毒性オリゴマー形態を特異的に認識する抗体ベースの試薬 |
| WO2015114538A1 (en) | 2014-01-28 | 2015-08-06 | F. Hoffmann-La Roche Ag | Camelid single-domain antibody directed against phosphorylated tau proteins and methods for producing conjugates thereof |
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| FEBS Lett.，2004年06月18日，Vol.568, No.1-3，pp.178-182 |
| Journal of Controlled Release，2016年10月06日，Vol.243，pp.1-10，Epub |
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| US10590191B2 (en) | 2020-03-17 |
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| CA3041066A1 (fr) | 2018-05-03 |
| WO2018078140A1 (fr) | 2018-05-03 |
| CN110225926B (zh) | 2024-05-03 |
| US20190263898A1 (en) | 2019-08-29 |
| FR3058143B1 (fr) | 2021-03-12 |
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