JP7189772B2 - 胃内滞留システムのための材料構造物 - Google Patents

胃内滞留システムのための材料構造物 Download PDF

Info

Publication number
JP7189772B2
JP7189772B2 JP2018561622A JP2018561622A JP7189772B2 JP 7189772 B2 JP7189772 B2 JP 7189772B2 JP 2018561622 A JP2018561622 A JP 2018561622A JP 2018561622 A JP2018561622 A JP 2018561622A JP 7189772 B2 JP7189772 B2 JP 7189772B2
Authority
JP
Japan
Prior art keywords
drug
carrier polymer
polymer
segment
gastric retention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2018561622A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019521968A5 (cg-RX-API-DMAC7.html
JP2019521968A (ja
Inventor
ベリンガー アンドリュー
カナスティー ローズマリー
グラント タイラー
ビース ヌプラ
ディベネディクティス ロバート
ヤン チョン
ゼール スティーブン
クリアー ジョン
Original Assignee
リンドラ セラピューティクス， インコーポレイティド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by リンドラ セラピューティクス， インコーポレイティド filed Critical リンドラ セラピューティクス， インコーポレイティド
Publication of JP2019521968A publication Critical patent/JP2019521968A/ja
Publication of JP2019521968A5 publication Critical patent/JP2019521968A5/ja
Priority to JP2022193244A priority Critical patent/JP7615112B2/ja
Application granted granted Critical
Publication of JP7189772B2 publication Critical patent/JP7189772B2/ja
Priority to JP2024231677A priority patent/JP2025060940A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
    • A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0013—Implantable devices or invasive measures
    • A61F5/0036—Intragastrical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A61L2300/604—Biodegradation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Child & Adolescent Psychology (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Nursing (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
JP2018561622A 2016-05-27 2017-05-26 胃内滞留システムのための材料構造物 Active JP7189772B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022193244A JP7615112B2 (ja) 2016-05-27 2022-12-02 胃内滞留システムのための材料構造物
JP2024231677A JP2025060940A (ja) 2016-05-27 2024-12-27 胃内滞留システムのための材料構造物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662342798P 2016-05-27 2016-05-27
US62/342,798 2016-05-27
PCT/US2017/034856 WO2017205844A2 (en) 2016-05-27 2017-05-26 Materials architecture for gastric residence systems

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022193244A Division JP7615112B2 (ja) 2016-05-27 2022-12-02 胃内滞留システムのための材料構造物

Publications (3)

Publication Number Publication Date
JP2019521968A JP2019521968A (ja) 2019-08-08
JP2019521968A5 JP2019521968A5 (cg-RX-API-DMAC7.html) 2020-07-09
JP7189772B2 true JP7189772B2 (ja) 2022-12-14

Family

ID=60412951

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018561622A Active JP7189772B2 (ja) 2016-05-27 2017-05-26 胃内滞留システムのための材料構造物
JP2022193244A Active JP7615112B2 (ja) 2016-05-27 2022-12-02 胃内滞留システムのための材料構造物
JP2024231677A Pending JP2025060940A (ja) 2016-05-27 2024-12-27 胃内滞留システムのための材料構造物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022193244A Active JP7615112B2 (ja) 2016-05-27 2022-12-02 胃内滞留システムのための材料構造物
JP2024231677A Pending JP2025060940A (ja) 2016-05-27 2024-12-27 胃内滞留システムのための材料構造物

Country Status (7)

Country Link
US (2) US12109305B2 (cg-RX-API-DMAC7.html)
EP (1) EP3463313A4 (cg-RX-API-DMAC7.html)
JP (3) JP7189772B2 (cg-RX-API-DMAC7.html)
CN (2) CN119925721A (cg-RX-API-DMAC7.html)
AU (1) AU2017268840B2 (cg-RX-API-DMAC7.html)
CA (1) CA3025650A1 (cg-RX-API-DMAC7.html)
WO (1) WO2017205844A2 (cg-RX-API-DMAC7.html)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106573999A (zh) 2014-06-11 2017-04-19 麻省理工学院 驻留结构及相关方法
US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
CN107592803B (zh) 2015-05-01 2021-01-22 麻省理工学院 可触发形状记忆感应装置
WO2017070612A1 (en) 2015-10-23 2017-04-27 Lyndra, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
ES2963058T3 (es) 2015-12-08 2024-03-25 Lyndra Therapeutics Inc Configuraciones geométricas para sistemas de residencia gástrica
US12109305B2 (en) * 2016-05-27 2024-10-08 Lyndra Therapeutics, Inc. Materials architecture for gastric residence systems
WO2018064630A1 (en) 2016-09-30 2018-04-05 Lyndra, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs
AU2018269711B2 (en) 2017-05-17 2023-07-27 Massachusetts Institute Of Technology Self-righting systems and related components and methods
US11541015B2 (en) 2017-05-17 2023-01-03 Massachusetts Institute Of Technology Self-righting systems, methods, and related components
US12023406B2 (en) 2017-06-09 2024-07-02 Lyndra Therapeutics, Inc. Gastric residence systems with release rate-modulating films
AU2019269636A1 (en) 2018-05-17 2020-11-19 Massachusetts Institute Of Technology Systems for electrical stimulation
AU2019321648A1 (en) * 2018-08-15 2021-03-18 Lyndra Therapeutics, Inc. Systems for enteric delivery of therapeutic agents
WO2020117855A1 (en) * 2018-12-03 2020-06-11 Lyndra, Inc. Stomach simulating device
EP3917598B1 (en) 2019-02-01 2025-10-29 Massachusetts Institute of Technology Systems for liquid injection
CA3134049A1 (en) 2019-03-20 2020-09-24 Lyndra Therapeutics, Inc. Capsules and capsule coatings for gastric residence dosage forms
WO2021019336A1 (en) * 2019-07-29 2021-02-04 3M Innovative Properties Company Antimicrobial compositions and articles comprising the same
US20230190941A1 (en) * 2019-11-08 2023-06-22 Lyndra Therapeutics, Inc. Polymeric linkers for a gastric residence system
WO2021092491A1 (en) * 2019-11-08 2021-05-14 Lyndra, Inc. Gastric residence systems for administration of active agents
US11541216B2 (en) 2019-11-21 2023-01-03 Massachusetts Institute Of Technology Methods for manufacturing tissue interfacing components
CN111544592B (zh) * 2020-03-13 2022-05-03 中山大学附属第一医院 模式识别受体Dectin-1抑制剂对受体移植物的免疫保护及诱导免疫耐受的应用
WO2022019876A1 (en) 2020-07-20 2022-01-27 Hewlett-Packard Development Company, L.P. Three-dimensional printing
JP2023536456A (ja) 2020-07-29 2023-08-25 ザ・セカント・グループ・エルエルシー 架橋ポリ（セバシン酸グリセロール）を含む構造を含む形状誘導型制御放出および保持
JP2023553010A (ja) 2020-12-03 2023-12-20 バテル・メモリアル・インスティテュート 非ウイルス性送達のためのポリマーナノ粒子およびｄｎａナノ構造組成物ならびに方法
EP4477215A3 (en) 2020-12-08 2025-02-19 Ruminant Biotech Corp Limited Improvements to devices and methods for delivery of substances to animals
US20240390270A1 (en) * 2021-01-19 2024-11-28 Lyndra Therapeutics, Inc. Gastric residence systems for administration of risperidone
JP2024516108A (ja) 2021-04-07 2024-04-12 バテル・メモリアル・インスティテュート 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術
US20240252483A1 (en) * 2021-05-05 2024-08-01 Lyndra Therapeutics, Inc. Gastric residence systems comprising buprenorphine and naloxone
WO2025042349A1 (en) * 2023-08-24 2025-02-27 Junion Therapeutics (Xiamen) Co., Ltd. A gastric residence article for oral administration
WO2025042350A1 (en) * 2023-08-24 2025-02-27 Junion Therapeutics (Xiamen) Co., Ltd. A gastric residence article for oral administration
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
WO2025122954A1 (en) 2023-12-08 2025-06-12 Battelle Memorial Institute Use of dna origami nanostructures for molecular information based data storage systems
WO2025195482A1 (zh) * 2024-03-22 2025-09-25 厦门君德医药科技有限公司 一种胃滞留装置
CN120267955B (zh) * 2025-06-06 2025-09-19 浙江大学 一种自发电胃驻留电子胶囊及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015191920A1 (en) 2014-06-11 2015-12-17 Massachusetts Institute Of Technology Residence structures and related methods

Family Cites Families (153)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1957564A (en) 1932-11-23 1934-05-08 Aubra T West Expanding capsule body
US3154461A (en) 1960-03-07 1964-10-27 Minnesota Mining & Mfg Matte-finish polymeric film and method of forming the same
US3531368A (en) 1966-01-07 1970-09-29 Toray Industries Synthetic filaments and the like
US3716614A (en) 1969-05-12 1973-02-13 Toray Industries Process of manufacturing collagen fiber-like synthetic superfine filament bundles
AU449029B2 (en) 1969-08-28 1974-04-17 Commonwealth Scientific And Industrial Research Organisation Device for administration to ruminants
JPS5512411B2 (cg-RX-API-DMAC7.html) 1974-03-12 1980-04-02
US4304767A (en) 1980-05-15 1981-12-08 Sri International Polymers of di- (and higher functionality) ketene acetals and polyols
FI75816C (fi) 1981-02-06 1988-08-08 Ucb Sa Foerfarande foer framstaellning av terapeutiskt aktiv 2-/4-(difenylmetyl)-1-piperazinyl/-aettiksyror eller dess amid.
US4451260A (en) 1982-03-26 1984-05-29 Minnesota Mining And Manufacturing Company Sustained release oral medicinal delivery device
US4676507A (en) 1985-05-06 1987-06-30 Patterson Bruce D Puzzles forming platonic solids
US4735804A (en) 1985-05-10 1988-04-05 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
CA1273872A (en) 1985-05-10 1990-09-11 Larry J. Caldwell Drug delivery device which can be retained in the stomach for a controlled period of time
US4758436A (en) 1985-05-29 1988-07-19 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US4767627A (en) * 1985-05-29 1988-08-30 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
EP0253554A3 (en) 1986-07-15 1988-07-20 Pfizer Inc. Controlled release drug-containing fibers
CA1314742C (en) 1986-12-12 1993-03-23 Hiromu Terada Optical fiber array
IL87710A (en) 1987-09-18 1992-06-21 Ciba Geigy Ag Covered floating retard form for controlled release in gastric juice
US5002772A (en) * 1988-05-31 1991-03-26 Pfizer Inc. Gastric retention system for controlled drug release
NZ228382A (en) 1989-03-17 1992-08-26 Carter Holt Harvey Plastic Pro Drug administering coil-like device for insertion in body cavity of animal
US5007790A (en) 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
NZ234227A (en) 1989-06-30 1991-08-27 Smithkline Beecham Corp Delayed release dosage form
JPH03163011A (ja) * 1989-08-31 1991-07-15 Yamanouchi Pharmaceut Co Ltd 胃内滞留デバイス
US5047464A (en) 1989-09-20 1991-09-10 Merck & Co., Inc. Bioerodible thermoset elastomers
US5121329A (en) 1989-10-30 1992-06-09 Stratasys, Inc. Apparatus and method for creating three-dimensional objects
JP2648897B2 (ja) 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
US5939467A (en) 1992-06-26 1999-08-17 The Procter & Gamble Company Biodegradable polymeric compositions and products thereof
US5369142A (en) 1993-01-15 1994-11-29 The Ohio State University Water soluble polymers containing amino acid residues for dental restoratives
WO1995003558A1 (en) 1993-07-19 1995-02-02 Reflexite Corporation Retroreflective structure
DE4406424A1 (de) 1994-02-28 1995-08-31 Bayer Ag Expandierbare Arzneiformen
US5837276A (en) * 1994-09-02 1998-11-17 Delab Apparatus for the delivery of elongate solid drug compositions
DE69624227T2 (de) 1995-03-23 2003-06-12 Advanced Animal Technology Ltd., Hamilton Substanzabgabevorrichtung
US6962579B2 (en) 1995-03-23 2005-11-08 Advanced Animal Technology Limited Substance delivery device
DE19539361A1 (de) * 1995-10-23 1997-04-24 Basf Ag Verfahren zur Herstellung von mehrschichtigen, festen Arzneiformen zur oralen oder rektalen Verabreichung
US5840332A (en) 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
WO1997038969A1 (en) 1996-04-12 1997-10-23 Japan Atomic Energy Research Institute pH-SENSITIVE POLYMERS
US5762637A (en) 1996-08-27 1998-06-09 Scimed Life Systems, Inc. Insert molded catheter tip
DE69828289T2 (de) 1997-08-11 2005-06-02 Alza Corp., Mountain View Dosierungsform für verzögerte Freisetzung eines Wirkstoffs
DE19850309A1 (de) 1998-10-30 2000-05-04 Lohmann Therapie Syst Lts Expandierbares gastroretensives Therapiesystem mit verlängerter Magenverweildauer
IL133196A0 (en) 1999-11-29 2001-03-19 Yissum Res Dev Co Gastroretentive controlled release pharmaceutical dosage forms
GB0001621D0 (en) 2000-01-26 2000-03-15 Astrazeneca Ab Pharmaceutical compositions
EP1286663B1 (en) 2000-05-18 2006-01-18 Therics, Inc. Encapsulating a toxic core within a non-toxic region in an oral dosage form
US20020022048A1 (en) 2000-05-26 2002-02-21 Bromberg Lev E. Composite wafer for controlled drug delivery
US6488962B1 (en) 2000-06-20 2002-12-03 Depomed, Inc. Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
US8158143B2 (en) 2000-07-14 2012-04-17 Helmholtz-Zentrum Geesthacht Zentrum Fuer Material- Und Kuestenforschung Gmbh Systems for releasing active ingredients, based on biodegradable or biocompatible polymers with a shape memory effect
US7803392B2 (en) 2000-12-27 2010-09-28 University Of Kentucky Research Foundation pH-Sensitive mucoadhesive film-forming gels and wax-film composites suitable for topical and mucosal delivery of molecules
US6627206B2 (en) 2001-07-25 2003-09-30 Greg A. Lloyd Method and apparatus for treating obesity and for delivering time-released medicaments
US20040219186A1 (en) 2001-08-16 2004-11-04 Ayres James W. Expandable gastric retention device
BR0117123A (pt) 2001-08-16 2004-09-28 Oregon State Dispositivo de retenção gástrica expansìvel
US20050165136A1 (en) 2002-01-23 2005-07-28 Uab Research Foundation Glass-ionomer cements containing amino acids
WO2003089506A1 (en) 2002-04-22 2003-10-30 Purdue Research Foundation Hydrogels having enhanced elasticity and mechanical strength properties
DE10224352A1 (de) 2002-06-01 2003-12-11 Mueller Schulte Detlef Thermosensitive Polymerträger mit veränderbarer physikalischer Struktur für die biochemische Analytik, Diagnostik und Therapie
GB0214013D0 (en) 2002-06-18 2002-07-31 Euro Celtique Sa Pharmaceutical product
TWI336260B (en) 2002-07-25 2011-01-21 Glaxo Group Ltd Dosage form suitable for retaining drug substance
AU2003282603A1 (en) 2002-10-11 2004-05-04 Depomed Development Ltd Gastro-retentive levodopa delivery form
CA2516285A1 (en) 2003-02-19 2004-09-02 Mnemoscience Gmbh Self-expanding device for the gastrointestinal or urogenital area
JP4497833B2 (ja) 2003-04-21 2010-07-07 富士フイルム株式会社 ポジ型平版印刷版原版
US7662864B2 (en) 2003-06-04 2010-02-16 Rutgers, The State University Of New Jersey Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent
BRPI0411437B8 (pt) 2003-06-13 2021-06-22 Gkss Forschungszentrum Geesthacht Gmbh stent para uso no campo não-vascular ou vascular, método para sua fabricação e kit compreendendo esse stent
EP1638533A1 (en) 2003-06-18 2006-03-29 John Michael Newton Controlled release devices with lumens
US20090259236A2 (en) 2003-07-28 2009-10-15 Baronova, Inc. Gastric retaining devices and methods
US8048169B2 (en) 2003-07-28 2011-11-01 Baronova, Inc. Pyloric valve obstructing devices and methods
US6825308B1 (en) 2003-10-29 2004-11-30 Council Of Scientific And Industrial Research Copolymers and preparation thereof
DE10350556A1 (de) 2003-10-29 2005-06-02 Clariant Gmbh Wasserbasierende Pigmentpräparationen
CA2549195A1 (en) 2003-12-09 2005-06-23 Spherics, Inc. Bioadhesive polymers with catechol functionality
CA2552126A1 (en) 2003-12-31 2005-07-21 Actavis Group Hf Ziprasidone formulations
US20080089933A1 (en) 2006-10-16 2008-04-17 Amir Alon Device and method for reducing calorie intake
AR048033A1 (es) 2004-03-12 2006-03-22 Smithkline Beecham Plc Composicion farmaceutica para moldear componentes que comprende copolimero de poli(met)acrilato, cubierta, conector o espaciador de capsula moldeado por inyeccion que tiene la composicion farmaceutica y forma de dosificacion farmaceutica de multicomponentes a partir de dicha composicion
AU2005287383B2 (en) 2004-05-25 2011-09-22 Chimeros, Inc. Self-assembling nanoparticle drug delivery system
DE102004047076A1 (de) 2004-09-28 2006-04-06 Zimmer Ag Verfahren zur Herstellung von Polyestern
IL166183A0 (en) 2005-01-06 2006-01-15 Yissum Res Dev Co Novel diagnostic and imaging techniques of the gi tract
RU2411045C2 (ru) 2005-01-27 2011-02-10 Институт Нефтехимического Синтеза Имени А.В. Топчиева Ран Гидрофильные биологически совместимые адгезивные композиции и их применение
EP1843755B1 (en) 2005-02-01 2015-04-01 Emisphere Technologies, Inc. Gastric retention and controlled release delivery system
US7785291B2 (en) 2005-03-01 2010-08-31 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants
JP2006323082A (ja) 2005-05-18 2006-11-30 Canon Inc 現像剤補給容器
US8021384B2 (en) 2005-07-26 2011-09-20 Ram Weiss Extending intrabody capsule
CN101175571A (zh) 2005-08-05 2008-05-07 滋贺县 含有共混聚合物而成的液体中物质转移材料
US20070048383A1 (en) 2005-08-25 2007-03-01 Helmus Michael N Self-assembled endovascular structures
WO2007048223A2 (en) 2005-10-25 2007-05-03 Pharmascience Inc. A gastric retention drug delivery system
WO2007072495A2 (en) 2005-11-03 2007-06-28 Sun Pharmaceutical Industries Limited Coated tablets having prolonged gastric retention
US7674396B2 (en) * 2005-11-08 2010-03-09 Plensat Llc Method and system for treatment of eating disorders
TR201902010T4 (tr) 2006-01-18 2019-03-21 Intec Pharma Ltd Bir ajanın oral alımına yönelik taşıyıcı cihaz.
WO2007093999A1 (en) 2006-02-15 2007-08-23 Intec Pharma Ltd. A gastro-retentive system for the delivery of macromolecules
US20090246142A1 (en) 2006-03-10 2009-10-01 Massachusetts Institute Of Technology Triggered Self-Assembly of Nanoparticles In Vivo
US7691151B2 (en) 2006-03-31 2010-04-06 Spiration, Inc. Articulable Anchor
US20070264307A1 (en) 2006-05-15 2007-11-15 Medtronic Vascular, Inc. Biodegradable Modified Caprolactone Polymers for Fabricating and Coating Medical Devices
EP1886665A1 (en) 2006-08-01 2008-02-13 Boehringer Ingelheim Pharma GmbH & Co. KG Gastro retentive delivery system
CA2661172A1 (en) 2006-09-04 2008-05-29 Panacea Biotec Limited Programmable buoyant delivery technology
US20080075766A1 (en) 2006-09-25 2008-03-27 Shun-Por Li Multi-core dosage form having transparent outer coating
EP2063867A2 (en) 2006-12-22 2009-06-03 Combinatorx, Incorporated Pharmaceutical compositions for treatment of parkinson's disease and related disorders
WO2008140651A2 (en) 2007-03-13 2008-11-20 Olson Arthur J Self-assembled polyhedra
US20100297009A1 (en) 2007-03-13 2010-11-25 Technion Research & Development Foundation Ltd. Self-assembled polyhedral multimeric chemical structures
US20080249156A1 (en) 2007-04-09 2008-10-09 Palepu Nageswara R Combinations of statins and anti-obesity agent and glitazones
US10010612B2 (en) 2007-05-25 2018-07-03 Indivior Uk Limited Sustained delivery formulations of risperidone compounds
JP2010527712A (ja) 2007-05-25 2010-08-19 ゴーラム エンタープライゼス エルエルシー 肥満症用の磁気装置およびその製造方法
US8038659B2 (en) 2007-10-17 2011-10-18 The Invention Science Fund I, Llc Disintegrating digestive tract interaction system
US8637455B2 (en) 2007-10-22 2014-01-28 Affinergy, Llc Compositions and methods for delivery of glycopeptide antibiotics to medical device surfaces
US8974814B2 (en) * 2007-11-12 2015-03-10 California Institute Of Technology Layered drug delivery polymer monofilament fibers
WO2009114118A2 (en) 2008-03-08 2009-09-17 Theraquest Biosciences, Inc. Oral pharmaceutical compositions of buprenorphine and method of use
AU2009223061B2 (en) 2008-03-11 2014-10-09 Depomed Inc. Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic
US20130273135A1 (en) 2008-03-25 2013-10-17 University Of Utah Research Foundation Controlled Release Combination Biomaterials
EP2276473B1 (en) 2008-04-18 2016-09-14 Intec Pharma Ltd. Gastroretentive drug delivery for carbidopa/levodopa
WO2009132461A1 (en) 2008-04-28 2009-11-05 Electronic Dietary Foods Inc. Bezoar-forming units for weight control
US20100256342A1 (en) 2008-08-12 2010-10-07 Francis Raymond Salemme Protein nodes for controlled nanoscale assembly
KR20110042366A (ko) 2008-08-18 2011-04-26 팀 아카데미 오브 파마슈티컬 사이언스 위장체류 약물 전달 시스템, 제작 방법 및 그것들의 사용
WO2010035273A2 (en) 2008-09-29 2010-04-01 Intec Pharma Ltd. Novel gastroretentive delivery system
CA2737753C (en) 2008-10-10 2017-03-14 Reva Medical, Inc. Expandable slide and lock stent
WO2010064139A2 (en) 2008-12-04 2010-06-10 Intec Pharma Ltd. Zaleplon gastroretentive drug delivery system
CA2746989A1 (en) 2008-12-27 2010-07-01 Chandra S. Duggirala Devices for treating obesity and methods of using those devices
US9845237B2 (en) 2009-02-26 2017-12-19 The Regents Of The University Of California Supramolecular approach for preparation of size controllable nanoparticles
US8414559B2 (en) 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
WO2010132648A1 (en) 2009-05-15 2010-11-18 Intersect Ent, Inc. Expandable devices and methods therefor
DE102009028076A1 (de) 2009-07-29 2011-02-03 Evonik Röhm Gmbh Beschichtungsmittel zum Tauchbeschichten von Kapselhälften
US20110052700A1 (en) 2009-08-31 2011-03-03 Depomed, Inc. Gastric retentive pharmaceutical compositions for immediate and extended release of levosulpiride
WO2011032087A2 (en) 2009-09-11 2011-03-17 Replication Medical Inc. Swellable polymeric device for dietary regulation
WO2011048494A2 (en) 2009-10-19 2011-04-28 Intec Pharma Ltd. Novel gastroretentive dosage forms of poorly soluble drugs
US9421169B2 (en) 2009-11-20 2016-08-23 Covidien Lp Oral dosage forms for delivery of therapeutic agents
CN101711752B (zh) 2009-11-26 2011-09-21 中国科学院上海药物研究所 一种苯并异噁唑类衍生物的控释制剂及其制备方法
WO2011139796A2 (en) 2010-04-27 2011-11-10 The Johns Hopkins University Self-folding sub-centimeter structures
WO2012003968A1 (en) 2010-07-06 2012-01-12 Grünenthal GmbH Novel gastro- retentive dosage forms comprising a gaba analog and an opioid
WO2012018923A1 (en) 2010-08-05 2012-02-09 Taris Biomedical, Inc. Implantable drug delivery devices for genitourinary sites
US20120165793A1 (en) 2010-12-22 2012-06-28 Ethicon Endo-Surgery, Inc. Pill Catchers
US20120165794A1 (en) 2010-12-22 2012-06-28 Ethicon Endo-Surgery, Inc. Pill Catchers
US20120165792A1 (en) 2010-12-22 2012-06-28 Ethicon Endo-Surgery, Inc. Pill Catchers
US9107816B2 (en) 2011-02-04 2015-08-18 Taris Biomedical Llc Implantable device for controlled dissolution and diffusion of low solubility drug
US20130017264A1 (en) 2011-07-15 2013-01-17 Piramal Life Sciences Limited Alginate tube drug delivery system and method therefor
EP2764557A4 (en) 2011-09-26 2016-04-27 Univ Northeastern CUSTOMIZABLE INTEGRATED SENSORS
CN104010630A (zh) 2011-12-09 2014-08-27 普渡制药公司 包含聚(ε-己内酯)和聚氧乙烯的药物剂型
US8979887B2 (en) 2012-02-24 2015-03-17 Elwha Llc Devices, systems, and methods to control stomach volume
CA2879282C (en) 2012-07-16 2022-05-03 Hendrik Jan Cornelis Meijerink Gastro-retentive drug delivery system
US9307966B2 (en) 2012-08-15 2016-04-12 St. Jude Medical Puerto Rico Llc Vascular closure device anchor
RU2015107517A (ru) 2012-08-16 2016-10-10 Тева Фармасьютикал Индастриес Лтд. Фармацевтические композиции мемантина
US10441760B2 (en) 2013-03-01 2019-10-15 The Johns Hopkins University Self-actuating chemomechanical devices for delivery and extended release of therapeutic agents in the gastrointestinal tract
CN103654903A (zh) 2013-11-27 2014-03-26 西安交通大学 一种用于人体消化道吻合的磁性可降解装置
AU2014358675B2 (en) 2013-12-05 2019-10-03 Epitomee Medical Ltd Retentive devices and systems for in-situ release of pharmaceutical active agents
WO2015168297A1 (en) 2014-04-29 2015-11-05 Massachusetts Institute Of Technology Polymeric materials for bio-applications
US9872835B2 (en) 2014-05-26 2018-01-23 Grünenthal GmbH Multiparticles safeguarded against ethanolic dose-dumping
CN106535878B (zh) 2014-06-02 2022-11-01 科莱西奥生物科技有限公司 可张开的胃内滞留剂型
US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
CN107592803B (zh) 2015-05-01 2021-01-22 麻省理工学院 可触发形状记忆感应装置
WO2017070612A1 (en) 2015-10-23 2017-04-27 Lyndra, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
CN108601724A (zh) 2015-12-01 2018-09-28 克雷西奥生物科技有限公司 胃滞留装置
CA3007165A1 (en) 2015-12-02 2017-06-08 Clexio Biosciences Ltd. Device for preparing gastroretentive dosage forms
ES2963058T3 (es) 2015-12-08 2024-03-25 Lyndra Therapeutics Inc Configuraciones geométricas para sistemas de residencia gástrica
EP3246050A1 (de) * 2016-05-17 2017-11-22 BSN medical GmbH Wund- oder hautauflage
US12109305B2 (en) 2016-05-27 2024-10-08 Lyndra Therapeutics, Inc. Materials architecture for gastric residence systems
WO2018064630A1 (en) 2016-09-30 2018-04-05 Lyndra, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs
US20200230244A1 (en) 2016-11-09 2020-07-23 Massachusetts Institute Of Technology Triggerable hydrogel compositions and related methods
CN110035718B (zh) 2016-12-02 2021-04-06 克雷西奥生物科技有限公司 胃内滞留系统
US12023406B2 (en) 2017-06-09 2024-07-02 Lyndra Therapeutics, Inc. Gastric residence systems with release rate-modulating films
EP3684321B1 (en) 2017-09-20 2024-12-25 Lyndra Therapeutics, Inc. Encapsulation of gastric residence systems
US11547839B2 (en) 2017-12-04 2023-01-10 Clexio Biosciences Ltd. Long acting gastric residence system
US20190365645A1 (en) 2018-05-31 2019-12-05 Massachusetts Institute Of Technology Drug delivery articles for gram-level dosing
WO2020102650A2 (en) 2018-11-15 2020-05-22 Massachusetts Institute Of Technology Thermally controlled reconfigurable medical devices

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015191920A1 (en) 2014-06-11 2015-12-17 Massachusetts Institute Of Technology Residence structures and related methods

Also Published As

Publication number Publication date
US20190254966A1 (en) 2019-08-22
JP2023022246A (ja) 2023-02-14
EP3463313A4 (en) 2019-12-18
WO2017205844A3 (en) 2018-01-04
CN119925721A (zh) 2025-05-06
AU2017268840A1 (en) 2018-11-22
JP2025060940A (ja) 2025-04-10
JP7615112B2 (ja) 2025-01-16
CA3025650A1 (en) 2017-11-30
US20240423909A1 (en) 2024-12-26
WO2017205844A2 (en) 2017-11-30
EP3463313A2 (en) 2019-04-10
CN109310639A (zh) 2019-02-05
AU2017268840B2 (en) 2022-02-10
US12109305B2 (en) 2024-10-08
JP2019521968A (ja) 2019-08-08

Similar Documents

Publication Publication Date Title
JP7189772B2 (ja) 胃内滞留システムのための材料構造物
US20240342081A1 (en) Geometric configurations for gastric residence systems
CN114945355B (zh) 具有用于改进胃驻留的长丝的胃驻留系统
JP7588177B2 (ja) 放出速度調節フィルムを有する胃内滞留システム
US20220387312A1 (en) Gastric residence systems having arms with controlled stiffness for improved gastric residence
TWI837082B (zh) 用於胃滯留系統之材料架構
WO2024249946A2 (en) Manufacturing methods for gastric residence systems
JP2022128077A (ja) 錠剤、錠剤の製造方法、及び錠剤の製造方法に用いられるフィラメント
TW202500122A (zh) 用於胃滯留系統之材料架構
RU2806007C2 (ru) Геометрические компоновки систем длительного нахождения в желудке
HK40106006A (en) Geometric configurations for gastric residence systems
HK1259225B (en) Geometric configurations for gastric residence systems

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190513

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200526

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20200526

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20210601

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210824

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220201

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20220502

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220602

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20221004

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20221101

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20221202

R150 Certificate of patent or registration of utility model

Ref document number: 7189772

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150