JP7145998B2 - 試料調製装置 - Google Patents
試料調製装置 Download PDFInfo
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- JP7145998B2 JP7145998B2 JP2021015513A JP2021015513A JP7145998B2 JP 7145998 B2 JP7145998 B2 JP 7145998B2 JP 2021015513 A JP2021015513 A JP 2021015513A JP 2021015513 A JP2021015513 A JP 2021015513A JP 7145998 B2 JP7145998 B2 JP 7145998B2
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- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/12—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the preparation of the feed
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- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
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- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/56—Labware specially adapted for transferring fluids
- B01L3/567—Valves, taps or stop-cocks
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
- F04B53/10—Valves; Arrangement of valves
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B9/00—Piston machines or pumps characterised by the driving or driven means to or from their working members
- F04B9/08—Piston machines or pumps characterised by the driving or driven means to or from their working members the means being fluid
- F04B9/12—Piston machines or pumps characterised by the driving or driven means to or from their working members the means being fluid the fluid being elastic, e.g. steam or air
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B9/00—Piston machines or pumps characterised by the driving or driven means to or from their working members
- F04B9/14—Pumps characterised by muscle-power operation
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/14—Suction devices, e.g. pumps; Ejector devices
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- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4005—Concentrating samples by transferring a selected component through a membrane
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- G01N30/06—Preparation
- G01N30/14—Preparation by elimination of some components
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- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
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- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/291—Gel sorbents
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- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
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- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/069—Absorbents; Gels to retain a fluid
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- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0854—Double walls
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- B01L2400/00—Moving or stopping fluids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
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- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
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- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Description
Claims (8)
- 第1の部分と、前記第1の部分内に作動可能に収まることができる第2の部分とを含む手動で作動するポンプであって、前記第1の部分が液体試料を収容するための計量チャンバーを備える計量バルブ、可動計量部材および圧力放出チャネルを含み、前記第2の部分が前記第1の部分内に収まると、前記計量部材と作動可能に係合するように配置されたアクチュエータを前記第2の部分が含み、前記第2の部分が前記第1の部分に作動可能に係合すると、所定量の流体が出口チャネルを通って前記ポンプを出る、ポンプ。
- 前記出口チャネルが前記第2の部分、好ましくは前記アクチュエータ内に設けられている、請求項1に記載のポンプ。
- 前記計量部材が、前記計量チャンバーの上部が前記計量チャンバーの下部から分けられている初期位置から、前記圧力放出チャネルが前記計量チャンバーの下部と前記計量チャンバーの上部との間に流体連通をもたらす以降の位置まで移動できるように、前記計量部材および圧力放出チャネルが配置されている、請求項1~2のいずれか1項に記載のポンプ。
- 前記ポンプが単回使用である、請求項1~3のいずれか1項に記載のポンプ。
- 流体を計量するためのポンプであって、
試料チャンバーおよび計量チャンバーを含む容器と、
アクチュエータの遠位部分に開口部を有する流体出口チャネルを含有する前記アクチュエータとを含み、
前記アクチュエータの遠位端が前記試料チャンバー内に位置している第1の位置から、前記流体出口チャネルの前記開口部が前記計量チャンバー内に位置している第2の位置まで、前記アクチュエータが移動でき、および前記アクチュエータが第1の位置にあるとき、前記試料チャンバーが計量チャンバーと流体連通しており、および前記アクチュエータが第2の位置にあるとき、前記試料チャンバーが前記計量チャンバーから分離されており、
前記計量チャンバーが可動計量部材によって上部と下部に分けられており、および前記計量チャンバーが圧力放出チャネルをさらに含み、および
前記アクチュエータがその第1の位置からその第2の位置に移動されると、前記計量部材が上部を下部から分ける初期位置から、前記圧力放出チャネルが前記計量チャンバーの下部と前記計量チャンバーの上部との間に流体連通をもたらす以降の位置まで、前記計量部材が移動するように、前記計量部材、前記圧力放出チャネルおよび前記アクチュエータが配置されている、ポンプ。 - 前記アクチュエータが前記第2の位置にあるとき、環状シールが前記アクチュエータの外壁と係合して前記計量チャンバーから前記試料チャンバーを分ける、請求項5に記載のポンプ。
- 等温核酸増幅のための液体試料を調製する装置であって、請求項1~6のいずれか1項に記載のポンプと、核酸増幅阻害物質および/または蛍光物質を除去するための分離要素とを含む、装置。
- 前記分離要素がサイズ排除クロマトグラフィーゲルを含む分離チャンバーを含有する、請求項7に記載の装置。
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
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JP2022106857A JP2022160409A (ja) | 2015-11-05 | 2022-07-01 | 試料調製装置 |
JP2024001701A JP2024045194A (ja) | 2015-11-05 | 2024-01-10 | 試料調製装置 |
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GB1519565.4 | 2015-11-05 | ||
GBGB1519565.4A GB201519565D0 (en) | 2015-11-05 | 2015-11-05 | Sample preparation device |
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JP2018541523A Division JP7018889B2 (ja) | 2015-11-05 | 2016-10-31 | 試料調製装置 |
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JP2021092580A JP2021092580A (ja) | 2021-06-17 |
JP7145998B2 true JP7145998B2 (ja) | 2022-10-03 |
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JP2018541523A Active JP7018889B2 (ja) | 2015-11-05 | 2016-10-31 | 試料調製装置 |
JP2021015513A Active JP7145998B2 (ja) | 2015-11-05 | 2021-02-03 | 試料調製装置 |
JP2022106857A Pending JP2022160409A (ja) | 2015-11-05 | 2022-07-01 | 試料調製装置 |
JP2024001701A Pending JP2024045194A (ja) | 2015-11-05 | 2024-01-10 | 試料調製装置 |
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JP2024001701A Pending JP2024045194A (ja) | 2015-11-05 | 2024-01-10 | 試料調製装置 |
Country Status (12)
Country | Link |
---|---|
US (2) | US11185864B2 (ja) |
EP (2) | EP3370867B1 (ja) |
JP (4) | JP7018889B2 (ja) |
KR (2) | KR20180098241A (ja) |
CN (2) | CN114264538A (ja) |
AU (3) | AU2016348479B2 (ja) |
BR (1) | BR112018009053B1 (ja) |
CA (3) | CA3145606C (ja) |
DK (1) | DK3370867T3 (ja) |
ES (1) | ES2898875T3 (ja) |
GB (1) | GB201519565D0 (ja) |
WO (2) | WO2017075586A1 (ja) |
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---|---|---|---|---|
US9352312B2 (en) * | 2011-09-23 | 2016-05-31 | Alere Switzerland Gmbh | System and apparatus for reactions |
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