JP7111809B2 - 薬物送達デバイス用のスペーサアセンブリ - Google Patents
薬物送達デバイス用のスペーサアセンブリ Download PDFInfo
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
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- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
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- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
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- A61M5/2459—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
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- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M5/31515—Connection of piston with piston rod
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/3157—Means providing feedback signals when administration is completed
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
- A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
- A61M2005/14256—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means with means for preventing access to the needle after use
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
- A61M5/2466—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
- A61M2005/247—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase with fixed or steady piercing means, e.g. piercing under movement of ampoule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
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- A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/31516—Piston or piston-rod constructions, e.g. connection of piston with piston-rod reducing dead-space in the syringe barrel after delivery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
- A61M2205/584—Means for facilitating use, e.g. by people with impaired vision by visual feedback having a color code
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/1454—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons spring-actuated, e.g. by a clockwork
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
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- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
本出願は、2017年10月16日に出願された「薬物送達デバイス用のスペーサアセンブリ」と題する米国仮出願第62/572,704号の優先権を主張し、その開示全体が参照により本明細書に組み入れられている。
Claims (5)
- 薬物送達システム用の駆動アセンブリであって、
前記薬物送達システムは、
薬剤を受け取るように構成された容器と、
前記容器と流体連通するように配置されるように構成された針を含む針アクチュエータアセンブリと、を有し、
前記駆動アセンブリは、
容器内のストッパに係合し、そして移動させるように構成されたプランジャ部材であって、第1の位置および前記第1の位置から軸方向に離間された第2の位置を有しているプランジャ部材、
前記第1の位置から前記第2の位置に前記プランジャ部材を移動させるように構成された付勢部材、および
前記プランジャ部材と前記ストッパとの間に位置された長さ調整可能なスペーサアセンブリであって、前記プランジャ部材によって前記スペーサアセンブリに加えられる軸方向荷重に応じて軸方向に長さが調整可能な、スペーサアセンブリと、
を備え、
前記長さ調節可能なスペーサアセンブリは、内部プランジャと回転シャトルとを備えたスペーサ要素と、前記スペーサ要素が取り付けられているホルダーとを備え、
前記薬剤の送達中に、前記スペーサアセンブリに加えられた前記軸方向荷重は、前記容器内の前記薬剤の圧力によって前記ストッパを変形させ、これは、前記内部プランジャに後方力を提供し、回転シャトルの回転を防ぎ、
前記薬剤の送達が完了すると、前記ストッパの前記薬剤の前記圧力が低下し、前記内部プランジャの遠位変位および前記回転シャトルの回転が可能になり、
前記薬剤の送達が完了すると、前記回転シャトルの前記回転は、前記薬物送達システムの前記針の後退を引き起こす、
ことを特徴とする薬物送達システム用の駆動アセンブリ。 - 前記ホルダーは、ねじ係合によって前記ストッパに取り付けられることを特徴とする請求項1に記載のアセンブリ。
- 前記スペーサ要素が前記ホルダーに対して第1の位置にあるとき、前記スペーサアセンブリは長手方向に第1の長さを有し、前記スペーサ要素が前記ホルダーに対して第2の位置にあるとき、前記スペーサアセンブリは長手方向に第2の長さを有し、前記第1の長さが前記第2の長さよりも大きいことを特徴とする請求項1に記載のアセンブリ。
- 薬剤を注射するための薬物送達システムであって、
該システムは、
薬剤を受容するように構成された容器であって、前記容器内で動くように構成されたストッパおよび閉鎖体を備える容器、
駆動アセンブリであって、
前記ストッパを前記容器内で係合および移動させるように構成されたプランジャ部材であって、第1の位置および前記第1の位置から軸方向に離間された第2の位置を有しているプランジャ部材と、
前記プランジャ部材を前記第1の位置から前記第2の位置に移動させるように構成された付勢部材と、
前記プランジャ部材と前記ストッパとの間に位置された長さ調整可能なスペーサアセンブリと、を備える駆動アセンブリであって、前記プランジャ部材によって前記スペーサアセンブリに加えられる軸方向荷重に応じて軸方向に長さが調整可能な、スペーサアセンブリと、
前記長さ調節可能なスペーサアセンブリは、内部プランジャと回転シャトルとを備えたスペーサ要素と、前記スペーサ要素が取り付けられているホルダーと、
前記容器に流体連通して配置されるように構成された針を備える針アクチュエータアセンブリと、を備え
前記薬剤の送達中に、前記スペーサアセンブリに加えられた前記軸方向荷重は、前記容器内の前記薬剤の圧力によって前記ストッパを変形させ、これは、前記内部プランジャに後方力を提供し、回転シャトルの回転を防ぎ、
前記薬剤の送達が完了すると、前記ストッパの前記薬剤の前記圧力が低下し、前記内部プランジャの遠位変位および前記回転シャトルの回転が可能になり、
前記薬剤の送達が完了すると、前記回転シャトルの前記回転は、前記薬物送達システムの前記針の後退を引き起こす、
ことを特徴とする薬物送達システム。 - 前記ホルダーは、ねじ係合により、前記ストッパに取り付けられることを特徴とする請求項4に記載のシステム。
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US201762572704P | 2017-10-16 | 2017-10-16 | |
US62/572,704 | 2017-10-16 | ||
PCT/US2018/055895 WO2019079189A1 (en) | 2017-10-16 | 2018-10-15 | DISPENSING ASSEMBLY FOR DRUG DELIVERY DEVICE |
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EP (1) | EP3697479B1 (ja) |
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CN (2) | CN111432862B (ja) |
AU (3) | AU2018350899B2 (ja) |
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DK1762259T3 (da) | 2005-09-12 | 2011-01-03 | Unomedical As | Indføringsindretning til infusionssæt med en første og en anden fjederenhed |
WO2012123274A1 (en) | 2011-03-14 | 2012-09-20 | Unomedical A/S | Inserter system with transport protection |
WO2020236796A1 (en) | 2019-05-20 | 2020-11-26 | Unomedical A/S | Rotatable infusion device and methods thereof |
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AU2021203524B2 (en) | 2022-12-08 |
CN115804885A (zh) | 2023-03-17 |
JP7506116B2 (ja) | 2024-06-25 |
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AU2018350899A1 (en) | 2020-05-07 |
CN111432862A (zh) | 2020-07-17 |
AU2021203524A1 (en) | 2021-07-01 |
EP3697479A1 (en) | 2020-08-26 |
US20220257867A1 (en) | 2022-08-18 |
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