JP7071748B2 - 胃内滞留システム - Google Patents

胃内滞留システム Download PDF

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Publication number
JP7071748B2
JP7071748B2 JP2019529639A JP2019529639A JP7071748B2 JP 7071748 B2 JP7071748 B2 JP 7071748B2 JP 2019529639 A JP2019529639 A JP 2019529639A JP 2019529639 A JP2019529639 A JP 2019529639A JP 7071748 B2 JP7071748 B2 JP 7071748B2
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JP
Japan
Prior art keywords
arm
gastric
arms
grdf
stomach
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2019529639A
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English (en)
Japanese (ja)
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JP2019536800A (ja
JP2019536800A5 (enExample
Inventor
メナケム、アヴシャロム ベン
ザリット、イラン
Original Assignee
クレキシオ バイオサイエンシーズ エルティーディー．
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Publication of JP2019536800A publication Critical patent/JP2019536800A/ja
Publication of JP2019536800A5 publication Critical patent/JP2019536800A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
    • A61F5/41—Devices for promoting penis erection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6871—Stomach
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6903—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/50—Prostheses not implantable in the body
    • A61F2002/5016—Prostheses not implantable in the body adjustable
    • A61F2002/5036—Prostheses not implantable in the body adjustable self-adjustable, e.g. self-learning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
    • A61F5/41—Devices for promoting penis erection
    • A61F2005/412—Devices for promoting penis erection by vacuum means

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Physiology (AREA)
  • Surgery (AREA)
  • Nutrition Science (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Reproductive Health (AREA)
  • Nursing (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Soil Working Implements (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2019529639A 2016-12-02 2017-12-04 胃内滞留システム Expired - Fee Related JP7071748B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662429095P 2016-12-02 2016-12-02
US62/429,095 2016-12-02
US201662430166P 2016-12-05 2016-12-05
US62/430,166 2016-12-05
PCT/US2017/064417 WO2018102799A1 (en) 2016-12-02 2017-12-04 Gastric residence system

Publications (3)

Publication Number Publication Date
JP2019536800A JP2019536800A (ja) 2019-12-19
JP2019536800A5 JP2019536800A5 (enExample) 2020-10-22
JP7071748B2 true JP7071748B2 (ja) 2022-05-19

Family

ID=61025040

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019529639A Expired - Fee Related JP7071748B2 (ja) 2016-12-02 2017-12-04 胃内滞留システム

Country Status (7)

Country Link
US (3) US10737079B2 (enExample)
EP (1) EP3547974B1 (enExample)
JP (1) JP7071748B2 (enExample)
CN (1) CN110035718B (enExample)
ES (1) ES2966736T3 (enExample)
IL (1) IL266377B2 (enExample)
WO (1) WO2018102799A1 (enExample)

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CN108472249A (zh) 2015-10-23 2018-08-31 林德拉有限公司 用于治疗剂缓释的胃驻留系统及其使用方法
EP3383365A1 (en) * 2015-12-01 2018-10-10 Clexio Biosciences Ltd. Gastric retentive devices
EP3386488B1 (en) 2015-12-08 2023-09-06 Lyndra Therapeutics, Inc. Geometric configurations for gastric residence systems
CN109310639A (zh) 2016-05-27 2019-02-05 林德拉有限公司 用于胃驻留系统的材料结构
JP2019532947A (ja) 2016-09-30 2019-11-14 リンドラ，インコーポレイティド アダマンタン系薬物の持続的送達のための胃内滞留システム
EP3547974B1 (en) 2016-12-02 2023-11-15 Clexio Biosciences Ltd. Gastric residence system
EP3634382A4 (en) 2017-06-09 2021-07-07 Lyndra Therapeutics, Inc. STOMACHING SYSTEMS WITH RELEASE RATE MODULATING FILMS
WO2019108580A1 (en) * 2017-11-28 2019-06-06 Massachusetts Institute Of Technology Gastric resident electronics
WO2019111132A1 (en) * 2017-12-04 2019-06-13 Clexio Biosciences Ltd. Long acting gastric residence system
US20220008701A1 (en) * 2018-11-15 2022-01-13 Massachusetts Institute Of Technology Millineedle systems for esophageal drug delivery
US12447130B2 (en) * 2019-03-20 2025-10-21 Lyndra Therapeutics, Inc. Capsules and capsule coatings for gastric residence dosage forms
CA3134186A1 (en) * 2019-03-20 2020-09-24 Lyndra Therapeutics, Inc. Coatings for gastric residence dosage forms
CA3139217A1 (en) 2019-05-14 2020-11-19 Clexio Biosciences Ltd. Treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease
AU2020360407B2 (en) * 2019-10-01 2026-04-09 Rani Therapeutics, Llc Self-sizing device for delivering a formulation to a lumen wall
WO2021092484A1 (en) * 2019-11-08 2021-05-14 Lyndra, Inc. Gastric residence systems having arms with controlled stiffness for improved gastric residence
AU2020378437B2 (en) * 2019-11-08 2026-05-14 Nortiva Bio, Inc. Formulations for release-rate modulating films for gastric residence systems
KR102391865B1 (ko) * 2020-04-03 2022-04-27 재단법인대구경북과학기술원 약물 전달 디바이스
US20230270575A1 (en) * 2020-08-30 2023-08-31 Teva Pharmaceutical Industries Ltd. Devices and methods for gastric retentive drug delivery
EP4301446A1 (en) * 2021-03-02 2024-01-10 Teva Pharmaceutical Industries Ltd. Retentive devices for gastrointestinal tract
WO2022195476A1 (en) 2021-03-15 2022-09-22 Clexio Biosciences Ltd. Gastroretentive devices for assessment of intragastric conditions
WO2023021480A1 (en) 2021-08-19 2023-02-23 Clexio Biosciences Ltd. Method of treating parkinson's disease
CN115518052B (zh) * 2022-09-22 2024-01-02 江苏集萃新型药物制剂技术研究所有限公司 胃滞留制剂及其制备方法
WO2024134599A1 (en) * 2022-12-21 2024-06-27 Teva Pharmaceutical Industries Ltd. Emptying monitoring system for gastrointestinal tract devices

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WO2015191920A1 (en) 2014-06-11 2015-12-17 Massachusetts Institute Of Technology Residence structures and related methods

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Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
US20130072869A1 (en) 2011-09-15 2013-03-21 The Johns Hopkins University Intra-Gastric Timed-Release Drug Delivery System
WO2015083171A1 (en) 2013-12-05 2015-06-11 Tulip Medical Ltd. Retentive devices and systems for in-situ release of pharmaceutical active agents
WO2015187746A1 (en) 2014-06-02 2015-12-10 Teva Pharmaceutical Industries Ltd. Expandable gastroretentive dosage form
WO2015191920A1 (en) 2014-06-11 2015-12-17 Massachusetts Institute Of Technology Residence structures and related methods

Also Published As

Publication number Publication date
US20200376242A1 (en) 2020-12-03
JP2019536800A (ja) 2019-12-19
US20230080008A1 (en) 2023-03-16
CN110035718A (zh) 2019-07-19
CN110035718B (zh) 2021-04-06
IL266377A (en) 2019-06-30
WO2018102799A1 (en) 2018-06-07
EP3547974A1 (en) 2019-10-09
US20200030589A1 (en) 2020-01-30
US11577061B2 (en) 2023-02-14
ES2966736T3 (es) 2024-04-24
US10737079B2 (en) 2020-08-11
EP3547974B1 (en) 2023-11-15
IL266377B1 (en) 2023-06-01
IL266377B2 (en) 2023-10-01

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