JP7065105B2 - 可溶性psgl-1タンパク質変異体の精製のための方法 - Google Patents

可溶性psgl-1タンパク質変異体の精製のための方法 Download PDF

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JP7065105B2
JP7065105B2 JP2019542078A JP2019542078A JP7065105B2 JP 7065105 B2 JP7065105 B2 JP 7065105B2 JP 2019542078 A JP2019542078 A JP 2019542078A JP 2019542078 A JP2019542078 A JP 2019542078A JP 7065105 B2 JP7065105 B2 JP 7065105B2
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buffer
concentration
protein
solid phase
chromatography
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JP2020506933A (ja
JP2020506933A5 (https=
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フェデリーコ マイサノ
フェデリーコ クリヴェリン
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Bracco Suisse SA
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2019542078A 2017-02-09 2018-02-06 可溶性psgl-1タンパク質変異体の精製のための方法 Active JP7065105B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17155366.2 2017-02-09
EP17155366 2017-02-09
PCT/EP2018/052889 WO2018146067A1 (en) 2017-02-09 2018-02-06 Process for the purification of soluble psgl-1 protein variants

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JP2020506933A JP2020506933A (ja) 2020-03-05
JP2020506933A5 JP2020506933A5 (https=) 2021-01-28
JP7065105B2 true JP7065105B2 (ja) 2022-05-11

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JP2019542078A Active JP7065105B2 (ja) 2017-02-09 2018-02-06 可溶性psgl-1タンパク質変異体の精製のための方法

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US (1) US12516102B1 (https=)
EP (1) EP3580231A1 (https=)
JP (1) JP7065105B2 (https=)
CN (1) CN110536896A (https=)
WO (1) WO2018146067A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003528884A (ja) 2000-03-27 2003-09-30 ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー 高アニオン性タンパク質の精製方法
JP2012507550A (ja) 2008-10-31 2012-03-29 ワイス・エルエルシー セラミックヒドロキシアパタイトクロマトグラフィーを使用する酸性タンパク質の精製
JP2016513643A (ja) 2013-03-14 2016-05-16 アムジエン・インコーポレーテツド 漏出したアフィニティ精製リガンドの除去
WO2017137477A1 (en) 2016-02-09 2017-08-17 Bracco Suisse Sa A recombinant chimeric protein for selectins targeting

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843707A (en) 1992-10-23 1998-12-01 Genetics Institute, Inc. Nucleic acid encoding a novel P-selectin ligand protein
US6277975B1 (en) 1992-10-23 2001-08-21 Genetics Institute, Inc. Fusions of P-selectin ligand protein and polynucleotides encoding same
WO2003059935A2 (en) * 2001-12-21 2003-07-24 Immunex Corporation Methods for purifying protein
EP1736538A1 (en) 2005-06-21 2006-12-27 Cytos Biotechnology AG Process for the preparative purification of virus-like-particles (VLPs)
EA017733B1 (ru) * 2006-08-28 2013-02-28 Арес Трейдинг С.А. СПОСОБ ОЧИСТКИ Fc-СЛИТЫХ БЕЛКОВ
US20080274501A1 (en) 2007-05-02 2008-11-06 Chenming Zhang Method of purifying acidic proteins expressed in plants

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003528884A (ja) 2000-03-27 2003-09-30 ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー 高アニオン性タンパク質の精製方法
JP2012507550A (ja) 2008-10-31 2012-03-29 ワイス・エルエルシー セラミックヒドロキシアパタイトクロマトグラフィーを使用する酸性タンパク質の精製
JP2016513643A (ja) 2013-03-14 2016-05-16 アムジエン・インコーポレーテツド 漏出したアフィニティ精製リガンドの除去
WO2017137477A1 (en) 2016-02-09 2017-08-17 Bracco Suisse Sa A recombinant chimeric protein for selectins targeting

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US12516102B1 (en) 2026-01-06
JP2020506933A (ja) 2020-03-05
CN110536896A (zh) 2019-12-03
EP3580231A1 (en) 2019-12-18
WO2018146067A1 (en) 2018-08-16

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