JP7017509B2 - がんを治療するための四環式キノロン類似体の併用療法 - Google Patents

がんを治療するための四環式キノロン類似体の併用療法 Download PDF

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JP7017509B2
JP7017509B2 JP2018526088A JP2018526088A JP7017509B2 JP 7017509 B2 JP7017509 B2 JP 7017509B2 JP 2018526088 A JP2018526088 A JP 2018526088A JP 2018526088 A JP2018526088 A JP 2018526088A JP 7017509 B2 JP7017509 B2 JP 7017509B2
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cancer
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pharmaceutical combination
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JP2018534321A (ja
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ジョン ソーン，
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センワ バイオサイエンシズ インコーポレイテッド
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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JP2018526088A 2015-11-20 2016-11-09 がんを治療するための四環式キノロン類似体の併用療法 Active JP7017509B2 (ja)

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JP2021197736A JP2022020003A (ja) 2015-11-20 2021-12-06 がんを治療するための四環式キノロン類似体の併用療法

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US201562258211P 2015-11-20 2015-11-20
US62/258,211 2015-11-20
PCT/US2016/061176 WO2017087235A1 (en) 2015-11-20 2016-11-09 Combination therapy of tetracyclic quinolone analogs for treating cancer

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JP2021197736A Division JP2022020003A (ja) 2015-11-20 2021-12-06 がんを治療するための四環式キノロン類似体の併用療法

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JP2018534321A JP2018534321A (ja) 2018-11-22
JP2018534321A5 JP2018534321A5 (enExample) 2020-02-13
JP7017509B2 true JP7017509B2 (ja) 2022-02-08

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JP2021197736A Withdrawn JP2022020003A (ja) 2015-11-20 2021-12-06 がんを治療するための四環式キノロン類似体の併用療法

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US (4) US10857156B2 (enExample)
EP (1) EP3377068B1 (enExample)
JP (2) JP7017509B2 (enExample)
KR (2) KR20180113976A (enExample)
CN (2) CN119185322A (enExample)
AU (3) AU2016355268B2 (enExample)
CA (1) CA3005730A1 (enExample)
IL (1) IL259423A (enExample)
RU (1) RU2752506C2 (enExample)
TW (1) TWI730013B (enExample)
WO (1) WO2017087235A1 (enExample)

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TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
AU2017330390A1 (en) * 2016-09-23 2019-04-18 The Johns Hopkins University Combinatory treatment strategies of cancer based on RNA polymerase I inhibition
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US11130740B2 (en) 2017-04-25 2021-09-28 Arbutus Biopharma Corporation Substituted 2,3-dihydro-1H-indene analogs and methods using same
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RU2020130050A (ru) * 2018-02-15 2022-03-15 Сэньхва Байосайенсиз, Инк. Аналоги хинолонов и их соли, композиции и способ их применения
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CN110075061A (zh) * 2019-03-13 2019-08-02 安庆瑄宇医药科技有限公司 一种尼拉帕尼口服液及其制备方法
WO2021030671A1 (en) 2019-08-14 2021-02-18 Senhwa Biosciences, Inc. Tetracyclic compounds and their salts, compositions, and methods for their use
KR20220124739A (ko) * 2020-01-09 2022-09-14 아스트라제네카 아베 암의 치료를 위한 병용 요법
CN113491768A (zh) * 2020-04-01 2021-10-12 深圳市罗湖区人民医院 Cd137抗体在制备促进nk细胞表达cd16分子的药物中的应用
WO2022036067A1 (en) * 2020-08-12 2022-02-17 Servier Pharmaceuticals, Llc Combination therapies for use in treating cancer
CN114409681A (zh) * 2022-03-18 2022-04-29 信义核新(北京)生物科技有限公司 用于治疗dna损伤修复缺陷肿瘤的喹诺酮类似物及其应用
CN115160341B (zh) * 2022-07-18 2023-07-18 中国医学科学院医学实验动物研究所 苯并噁嗪类化合物及其药物用途
CN119768184A (zh) * 2022-08-30 2025-04-04 东丽株式会社 用于癌的治疗和/或预防的药品
CN116063328B (zh) * 2023-03-29 2023-06-20 信义核新(北京)生物科技有限公司 一种四环喹诺酮化合物、药学上可接受的盐及其应用
WO2024222630A1 (zh) * 2023-04-23 2024-10-31 信义核新(北京)生物科技有限公司 喹诺酮衍生物及其在抗肿瘤中的应用
WO2024242545A1 (ko) * 2023-05-23 2024-11-28 (주) 메티메디제약 칼슘 락테이트를 활성 성분으로 포함하는 암 백신 조성물 및 그 용도
WO2025101688A1 (en) * 2023-11-08 2025-05-15 Mary Hitchcock Memorial Hospital For Itself And On Behalf Of Dartmouth-Hitchcock Clinic (Collectively Doing Business As Dartmouth-Hitchcock) Combination therapy using tetrathiomolybdate

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