JP7014731B2 - 置換アミノプリン化合物、その組成物、及びそれらを用いた治療方法 - Google Patents

置換アミノプリン化合物、その組成物、及びそれらを用いた治療方法 Download PDF

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JP7014731B2
JP7014731B2 JP2018551358A JP2018551358A JP7014731B2 JP 7014731 B2 JP7014731 B2 JP 7014731B2 JP 2018551358 A JP2018551358 A JP 2018551358A JP 2018551358 A JP2018551358 A JP 2018551358A JP 7014731 B2 JP7014731 B2 JP 7014731B2
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purine
cyclohexanecarboxamide
ylamino
chloro
difluorophenylamino
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JP2019510066A5 (enExample
JP2019510066A (ja
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エフ． ボーイラン ジョン
エル． ブライ ゴードン
フィルバロフ エレン
フバード ロバート
ミコロン デビッド
レイモン ヘザー
シ タオ
エム． トラン タム
俊也 辻
エル． ウォン リリー
シュ スイチャン
ズー ダン
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シグナル ファーマシューティカルズ，エルエルシー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2018551358A 2016-04-01 2017-03-31 置換アミノプリン化合物、その組成物、及びそれらを用いた治療方法 Active JP7014731B2 (ja)

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US201662317412P 2016-04-01 2016-04-01
US62/317,412 2016-04-01
PCT/US2017/025252 WO2017173206A1 (en) 2016-04-01 2017-03-31 Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith

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JP2019510066A5 JP2019510066A5 (enExample) 2020-05-07
JP7014731B2 true JP7014731B2 (ja) 2022-02-01

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IL (1) IL262007B2 (enExample)
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NZ (1) NZ746554A (enExample)
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JOP20180025B1 (ar) 2017-03-31 2021-08-17 Janssen Pharmaceuticals Inc مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
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CN115279368B (zh) * 2019-11-20 2024-05-24 维瓦斯治疗公司 杂芳基化合物
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KR102664454B1 (ko) * 2021-08-03 2024-05-09 한국생명공학연구원 젬시타빈에 대한 민감성 향상을 위한 신규 표적 및 이의 활용
CN114681456A (zh) * 2022-02-23 2022-07-01 中山大学附属第六医院 Plx3397在结直肠癌的治疗中的用途
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EA039392B1 (ru) 2022-01-21
JP2019510066A (ja) 2019-04-11
WO2017173206A1 (en) 2017-10-05
IL262007B2 (en) 2023-04-01
IL262007A (en) 2018-10-31
SG11201808388QA (en) 2018-10-30
AU2017241837A1 (en) 2018-10-25
MX2018011992A (es) 2019-01-24
CN109069512A (zh) 2018-12-21
AU2017241837B2 (en) 2021-07-22
EP3436018A4 (en) 2019-11-13
KR20180126497A (ko) 2018-11-27
CL2018002787A1 (es) 2019-01-18
SG10202009589UA (en) 2020-10-29
US20170281633A1 (en) 2017-10-05
US10576085B2 (en) 2020-03-03
EA201892229A1 (ru) 2019-03-29
IL262007B (en) 2022-12-01
EP3436018A1 (en) 2019-02-06
BR112018070163A2 (pt) 2019-01-29
NZ746554A (en) 2023-03-31
CN109069512B (zh) 2022-06-14
CA3018986A1 (en) 2017-10-05
KR102356433B1 (ko) 2022-01-27
MX379513B (es) 2025-03-11

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