JP6976263B2 - 免疫調節剤 - Google Patents

免疫調節剤 Download PDF

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Publication number
JP6976263B2
JP6976263B2 JP2018546499A JP2018546499A JP6976263B2 JP 6976263 B2 JP6976263 B2 JP 6976263B2 JP 2018546499 A JP2018546499 A JP 2018546499A JP 2018546499 A JP2018546499 A JP 2018546499A JP 6976263 B2 JP6976263 B2 JP 6976263B2
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JP
Japan
Prior art keywords
dmf
resin
minutes
fmoc
solution
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English (en)
Japanese (ja)
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JP2019512478A (ja
JP2019512478A5 (OSRAM
Inventor
マーティン・パトリック・アレン
エリック・ピー・ギリス
デイビッド・アール・ラングレー
マイケル・マシュー・ミラー
エリック・マル
リ−チアン・スン
カプ−スン・イェウン
キャサリン・エイ・グラント−ヤング
ニコラス・エイ・ミーンウェル
ポール・マイケル・スコラ
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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Publication of JP2019512478A publication Critical patent/JP2019512478A/ja
Publication of JP2019512478A5 publication Critical patent/JP2019512478A5/ja
Application granted granted Critical
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2018546499A 2016-03-04 2017-03-02 免疫調節剤 Active JP6976263B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662303673P 2016-03-04 2016-03-04
US62/303,673 2016-03-04
PCT/US2017/020304 WO2017151830A1 (en) 2016-03-04 2017-03-02 Immunomodulators

Publications (3)

Publication Number Publication Date
JP2019512478A JP2019512478A (ja) 2019-05-16
JP2019512478A5 JP2019512478A5 (OSRAM) 2020-04-09
JP6976263B2 true JP6976263B2 (ja) 2021-12-08

Family

ID=58347940

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018546499A Active JP6976263B2 (ja) 2016-03-04 2017-03-02 免疫調節剤

Country Status (19)

Country Link
US (1) US10143746B2 (OSRAM)
EP (1) EP3423470B1 (OSRAM)
JP (1) JP6976263B2 (OSRAM)
KR (1) KR102409246B1 (OSRAM)
CN (1) CN109153703B (OSRAM)
AR (1) AR107802A1 (OSRAM)
AU (1) AU2017227777B2 (OSRAM)
BR (1) BR112018017114A2 (OSRAM)
CA (1) CA3016024A1 (OSRAM)
CL (1) CL2018002506A1 (OSRAM)
CO (1) CO2018010316A2 (OSRAM)
EA (1) EA035134B1 (OSRAM)
ES (1) ES2886635T3 (OSRAM)
IL (1) IL261408B (OSRAM)
MX (1) MX379487B (OSRAM)
SG (1) SG11201807426WA (OSRAM)
TW (1) TW201734022A (OSRAM)
UY (1) UY37143A (OSRAM)
WO (1) WO2017151830A1 (OSRAM)

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Also Published As

Publication number Publication date
US20170252432A1 (en) 2017-09-07
UY37143A (es) 2017-08-31
EP3423470A1 (en) 2019-01-09
EP3423470B1 (en) 2021-08-18
JP2019512478A (ja) 2019-05-16
IL261408B (en) 2022-01-01
MX2018010414A (es) 2018-11-09
KR102409246B1 (ko) 2022-06-14
AU2017227777A1 (en) 2018-10-25
TW201734022A (zh) 2017-10-01
CN109153703A (zh) 2019-01-04
EA035134B1 (ru) 2020-04-30
AU2017227777B2 (en) 2021-07-01
CA3016024A1 (en) 2017-09-08
SG11201807426WA (en) 2018-09-27
CN109153703B (zh) 2022-09-23
BR112018017114A2 (pt) 2018-12-26
AR107802A1 (es) 2018-06-06
CL2018002506A1 (es) 2018-11-09
CO2018010316A2 (es) 2018-10-22
ES2886635T3 (es) 2021-12-20
MX379487B (es) 2025-03-11
US10143746B2 (en) 2018-12-04
IL261408A (en) 2018-10-31
KR20180118724A (ko) 2018-10-31
EA201891879A1 (ru) 2019-02-28
WO2017151830A1 (en) 2017-09-08

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