JP6966052B2 - 稀な配列変異体を検出するための組成物および方法 - Google Patents

稀な配列変異体を検出するための組成物および方法 Download PDF

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JP6966052B2
JP6966052B2 JP2019508937A JP2019508937A JP6966052B2 JP 6966052 B2 JP6966052 B2 JP 6966052B2 JP 2019508937 A JP2019508937 A JP 2019508937A JP 2019508937 A JP2019508937 A JP 2019508937A JP 6966052 B2 JP6966052 B2 JP 6966052B2
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polynucleotide
polynucleotides
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サン，ザオフイ
ウェン，リ
リン，シェンロン
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アキュラーゲン ホールディングス リミテッド
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    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6869—Methods for sequencing
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    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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JP2019508937A 2016-08-15 2017-08-15 稀な配列変異体を検出するための組成物および方法 Active JP6966052B2 (ja)

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JP2021166929A JP7365382B2 (ja) 2016-08-15 2021-10-11 稀な配列変異体を検出するための組成物および方法
JP2023172298A JP2024012298A (ja) 2016-08-15 2023-10-03 稀な配列変異体を検出するための組成物および方法

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US201662375396P 2016-08-15 2016-08-15
US62/375,396 2016-08-15
PCT/US2017/047029 WO2018035170A1 (en) 2016-08-15 2017-08-15 Compositions and methods for detecting rare sequence variants

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