JP6959738B2 - Ｔｌｒ−４特異的アプタマーおよびそれらの使用 - Google Patents

Ｔｌｒ−４特異的アプタマーおよびそれらの使用 Download PDF

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JP6959738B2
JP6959738B2 JP2016575345A JP2016575345A JP6959738B2 JP 6959738 B2 JP6959738 B2 JP 6959738B2 JP 2016575345 A JP2016575345 A JP 2016575345A JP 2016575345 A JP2016575345 A JP 2016575345A JP 6959738 B2 JP6959738 B2 JP 6959738B2
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tlr
aptamer
seq
complex
present
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JP2017527260A (ja
JP2017527260A5 (enExample
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ヘルナンデス，イグナシオ リザソアイン
ムノス，ビクトル マヌエル ゴンザレス
ゴメス−チャコン，ジェロニモ フェルナンデス
サンチェス，マリア エンジェル モロ
パルマ，マ エレナ マーチン
イエベネ，アナ モラガ
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Aptatargets SL
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Aptatargets SL
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
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    • C12N2310/00—Structure or type of the nucleic acid
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JP2016575345A 2014-06-24 2015-06-24 Ｔｌｒ−４特異的アプタマーおよびそれらの使用 Active JP6959738B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ESP201430955. 2014-06-24
ES201430955A ES2555160B1 (es) 2014-06-24 2014-06-24 Aptámeros específicos de TLR-4 y usos de los mismos
PCT/EP2015/064277 WO2015197706A1 (en) 2014-06-24 2015-06-24 Aptamers specific for tlr-4 and uses thereof

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JP2017527260A JP2017527260A (ja) 2017-09-21
JP2017527260A5 JP2017527260A5 (enExample) 2018-08-02
JP6959738B2 true JP6959738B2 (ja) 2021-11-05

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US (5) US10196642B2 (enExample)
EP (1) EP3161139B1 (enExample)
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US11591603B2 (en) 2023-02-28
US10196642B2 (en) 2019-02-05
BR112016030172B1 (pt) 2022-11-01
RU2709718C9 (ru) 2020-02-06
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US10808252B2 (en) 2020-10-20
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