RU2709718C9 - Аптамеры, специфические в отношении tlr-4, и их применение - Google Patents

Аптамеры, специфические в отношении tlr-4, и их применение Download PDF

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RU2709718C9
RU2709718C9 RU2016152094A RU2016152094A RU2709718C9 RU 2709718 C9 RU2709718 C9 RU 2709718C9 RU 2016152094 A RU2016152094 A RU 2016152094A RU 2016152094 A RU2016152094 A RU 2016152094A RU 2709718 C9 RU2709718 C9 RU 2709718C9
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tlr
aptamer
seq
present
complex
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RU2709718C2 (ru
RU2016152094A3 (enExample
RU2016152094A (ru
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ЭРНАНДЕС Игнасио ЛИСАСОАИН
МУНЬОС Виктор Мануэль ГОНСАЛЕС
ГОМЕС-ЧАКОН Херонимо ФЕРНАНДЕС
САНЧЕС Мария Анхелес МОРО
ПАЛЬМА Мария Элена МАРТИН
ЕБЕНЕС Ана МОРАГА
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Аптатархетс, С.Л.
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RU2016152094A 2014-06-24 2015-06-24 Аптамеры, специфические в отношении tlr-4, и их применение RU2709718C9 (ru)

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Application Number Priority Date Filing Date Title
ESP201430955 2014-06-24
ES201430955A ES2555160B1 (es) 2014-06-24 2014-06-24 Aptámeros específicos de TLR-4 y usos de los mismos
PCT/EP2015/064277 WO2015197706A1 (en) 2014-06-24 2015-06-24 Aptamers specific for tlr-4 and uses thereof

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RU2016152094A RU2016152094A (ru) 2018-07-26
RU2016152094A3 RU2016152094A3 (enExample) 2019-01-29
RU2709718C2 RU2709718C2 (ru) 2019-12-19
RU2709718C9 true RU2709718C9 (ru) 2020-02-06

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CA3030974A1 (en) 2016-07-15 2018-01-18 President And Fellows Of Harvard College Glycolipid compositions and methods of use
EP3494994A1 (en) * 2017-12-07 2019-06-12 Universität zu Köln Combinations of ripk1- and ikk-inhibitors for the prevention or treatment of immune diseases
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AU2019347774A1 (en) 2018-09-28 2021-03-25 Nutcracker Therapeutics, Inc. Lipid nanoparticle formulations comprising lipidated cationic peptide compounds for nucleic acid delivery
CN113423833B (zh) * 2018-09-28 2024-09-17 奥曼尼提纳米有限公司 用于选择功能性适体的方法和组合物
WO2020069569A1 (en) 2018-10-02 2020-04-09 WearOptimo Pty Ltd Actuator system
US20210338158A1 (en) 2018-10-02 2021-11-04 WearOptimo Pty Ltd Measurement system
US20220233572A1 (en) * 2019-05-16 2022-07-28 Aptatargets, S.L. Treatment of tlr-4 mediated diseases and conditions with aptamers targeting tlr-4
CN111474336B (zh) * 2020-03-21 2023-07-28 南昌大学 一种铁氰化镍纳米粒化学发光适体传感器的制备方法及基于其检测8-OhdG的方法
WO2021257494A1 (en) * 2020-06-15 2021-12-23 President And Fellows Of Harvard College Methods for modulating tlr4 signaling
CN114152599B (zh) * 2021-12-01 2023-10-13 中国农业大学 一种基于双劈裂功能核酸变构的孔雀石绿生物传感器
CN114836425A (zh) * 2022-02-25 2022-08-02 温州医科大学附属眼视光医院 检测小胶质细胞的核酸适体及应用
WO2024146930A1 (en) 2023-01-05 2024-07-11 Aptatargets, S.L. Aptoll molecules for the treatment of ischemic stroke and intracranial hemorrhages
WO2024240750A1 (en) 2023-05-22 2024-11-28 Aptatargets, S.L. New tlr-4 antagonist aptamers

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WO2006138681A2 (en) * 2005-06-17 2006-12-28 University Of Rochester Methods and compositions for enhancing immune memory by blocking intrahepatic activated t cell deletion
WO2010060030A1 (en) * 2008-11-24 2010-05-27 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Tlr ligand-nucleic acid nanostructure as a novel immune modulatory agent and method of using the same

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ES2555160A1 (es) 2015-12-29
MA40283A (fr) 2017-05-03
CA2953020A1 (en) 2015-12-30
RU2016152094A (ru) 2018-07-26
WO2015197706A1 (en) 2015-12-30
JP2017527260A (ja) 2017-09-21
BR112016030172A2 (pt) 2017-11-14
MX387405B (es) 2025-03-18
CN112111495A (zh) 2020-12-22
CN106459980A (zh) 2017-02-22
US11591603B2 (en) 2023-02-28
PL3161139T3 (pl) 2021-01-11
ZA201700363B (en) 2018-11-28
US20190211334A1 (en) 2019-07-11
US20210130830A1 (en) 2021-05-06
BR112016030172B1 (pt) 2022-11-01
AU2015279248A1 (en) 2017-01-12
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CA2953020C (en) 2023-01-10

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