JP6931229B2 - Ｂ７タンパク質をコードする腫瘍溶解性アデノウイルス - Google Patents

Ｂ７タンパク質をコードする腫瘍溶解性アデノウイルス Download PDF

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JP6931229B2
JP6931229B2 JP2017552966A JP2017552966A JP6931229B2 JP 6931229 B2 JP6931229 B2 JP 6931229B2 JP 2017552966 A JP2017552966 A JP 2017552966A JP 2017552966 A JP2017552966 A JP 2017552966A JP 6931229 B2 JP6931229 B2 JP 6931229B2
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cells
virus
protein
cell
transgene
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JP2018514199A5 (enExample
JP2018514199A (ja
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チャンピオン，ブライアン，ロバート
クレアー ノエル ブロムリー，アリス
クレアー ノエル ブロムリー，アリス
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サイオクサス セラピューティクス リミテッド
サイオクサス セラピューティクス リミテッド
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Priority to JP2018041788A priority Critical patent/JP6928380B2/ja
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    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
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    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
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    • C12N2710/10011—Adenoviridae
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JP2017552966A 2015-04-30 2016-04-29 Ｂ７タンパク質をコードする腫瘍溶解性アデノウイルス Active JP6931229B2 (ja)

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JP2018041788A JP6928380B2 (ja) 2015-04-30 2018-03-08 Ｂ７タンパク質をコードする腫瘍溶解性アデノウイルス
JP2021129196A JP7162929B2 (ja) 2015-04-30 2021-08-05 Ｂ７タンパク質をコードする腫瘍溶解性アデノウイルス

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GBGB1507419.8A GB201507419D0 (en) 2015-04-30 2015-04-30 Virus
GB1507419.8 2015-04-30
GB1516936.0 2015-09-24
GBGB1516936.0A GB201516936D0 (en) 2015-09-24 2015-09-24 Virus
GBGB1522013.0A GB201522013D0 (en) 2015-12-14 2015-12-14 Virus
GB1522013.0 2015-12-14
PCT/EP2016/059609 WO2016174200A1 (en) 2015-04-30 2016-04-29 Oncolytic adenovirus encoding a b7 protein

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JP2018041788A Division JP6928380B2 (ja) 2015-04-30 2018-03-08 Ｂ７タンパク質をコードする腫瘍溶解性アデノウイルス
JP2021129196A Division JP7162929B2 (ja) 2015-04-30 2021-08-05 Ｂ７タンパク質をコードする腫瘍溶解性アデノウイルス

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JP2018514199A5 JP2018514199A5 (enExample) 2019-06-06
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JP2018041788A Active JP6928380B2 (ja) 2015-04-30 2018-03-08 Ｂ７タンパク質をコードする腫瘍溶解性アデノウイルス
JP2021129196A Active JP7162929B2 (ja) 2015-04-30 2021-08-05 Ｂ７タンパク質をコードする腫瘍溶解性アデノウイルス

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JP2021129196A Active JP7162929B2 (ja) 2015-04-30 2021-08-05 Ｂ７タンパク質をコードする腫瘍溶解性アデノウイルス

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Cited By (1)

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JP2021176339A (ja) * 2015-04-30 2021-11-11 サイオクサス セラピューティクス リミテッド Ｂ７タンパク質をコードする腫瘍溶解性アデノウイルス

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JP6936221B2 (ja) 2015-11-02 2021-09-15 ファイブ プライム セラピューティクス， インコーポレイテッド Ｃｄ８０細胞外ドメインポリペプチドと、がん治療でのそれらの使用
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HUE072880T2 (hu) * 2016-03-31 2025-12-28 The European Molecular Biology Laboratory Adenovírus szálfehérjékbõl származó módosított polipeptidek és a polipeptideket tartalmazó VLP-k
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JP7394628B2 (ja) * 2017-06-01 2023-12-08 アカミス バイオ リミテッド 腫瘍溶解性ウイルスおよび方法
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