JP6913026B2 - インターロイキン36受容体(il−36r)に対する抗体 - Google Patents

インターロイキン36受容体(il−36r)に対する抗体 Download PDF

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JP6913026B2
JP6913026B2 JP2017553885A JP2017553885A JP6913026B2 JP 6913026 B2 JP6913026 B2 JP 6913026B2 JP 2017553885 A JP2017553885 A JP 2017553885A JP 2017553885 A JP2017553885 A JP 2017553885A JP 6913026 B2 JP6913026 B2 JP 6913026B2
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バウワーズ、ピーター
ジョン マックナイト、アンドリュー
ジョン マックナイト、アンドリュー
ジェイ. キング、デイヴィッド
ジェイ. キング、デイヴィッド
ロンデイ、マルコ
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アナプティスバイオ インコーポレイティッド
アナプティスバイオ インコーポレイティッド
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Mycology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2017553885A 2015-04-15 2016-04-15 インターロイキン36受容体(il−36r)に対する抗体 Active JP6913026B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2021069306A JP7212098B2 (ja) 2015-04-15 2021-04-15 インターロイキン36受容体(il-36r)に対する抗体
JP2023003385A JP7721585B2 (ja) 2015-04-15 2023-01-12 インターロイキン36受容体(il-36r)に対する抗体
JP2025127775A JP2025163120A (ja) 2015-04-15 2025-07-30 インターロイキン36受容体(il-36r)に対する抗体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562147824P 2015-04-15 2015-04-15
US62/147,824 2015-04-15
PCT/US2016/027676 WO2016168542A1 (en) 2015-04-15 2016-04-15 Antibodies directed against interleukin 36 receptor (il-36r)

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JP2021069306A Division JP7212098B2 (ja) 2015-04-15 2021-04-15 インターロイキン36受容体(il-36r)に対する抗体

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JP2018512157A JP2018512157A (ja) 2018-05-17
JP2018512157A5 JP2018512157A5 (https=) 2019-05-23
JP6913026B2 true JP6913026B2 (ja) 2021-08-04

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JP2017553885A Active JP6913026B2 (ja) 2015-04-15 2016-04-15 インターロイキン36受容体(il−36r)に対する抗体
JP2021069306A Active JP7212098B2 (ja) 2015-04-15 2021-04-15 インターロイキン36受容体(il-36r)に対する抗体
JP2023003385A Active JP7721585B2 (ja) 2015-04-15 2023-01-12 インターロイキン36受容体(il-36r)に対する抗体
JP2025127775A Pending JP2025163120A (ja) 2015-04-15 2025-07-30 インターロイキン36受容体(il-36r)に対する抗体

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JP2021069306A Active JP7212098B2 (ja) 2015-04-15 2021-04-15 インターロイキン36受容体(il-36r)に対する抗体
JP2023003385A Active JP7721585B2 (ja) 2015-04-15 2023-01-12 インターロイキン36受容体(il-36r)に対する抗体
JP2025127775A Pending JP2025163120A (ja) 2015-04-15 2025-07-30 インターロイキン36受容体(il-36r)に対する抗体

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US (4) US10526410B2 (https=)
EP (2) EP3283110B1 (https=)
JP (4) JP6913026B2 (https=)
KR (1) KR102666920B1 (https=)
CN (2) CN115925932A (https=)
AU (1) AU2016248208B2 (https=)
CA (1) CA2982555A1 (https=)
DK (1) DK3283110T3 (https=)
ES (1) ES2914243T3 (https=)
MX (2) MX2017013080A (https=)
PL (1) PL3283110T3 (https=)
RU (1) RU2745898C2 (https=)
SG (1) SG11201708061TA (https=)
WO (1) WO2016168542A1 (https=)

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JP2020512344A (ja) * 2017-03-27 2020-04-23 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 抗il−36r抗体併用治療
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CN112094349B (zh) * 2020-11-04 2021-02-09 上海华奥泰生物药业股份有限公司 靶向于白介素36r的抗体及其制备方法和应用
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US20200087408A1 (en) 2020-03-19
EP3283110A1 (en) 2018-02-21
JP2023040236A (ja) 2023-03-22
CN115925932A (zh) 2023-04-07
MX2023001791A (es) 2023-03-10
US10526410B2 (en) 2020-01-07
JP7721585B2 (ja) 2025-08-12
EP3283110A4 (en) 2019-02-27
NZ736535A (en) 2024-08-30
RU2745898C2 (ru) 2021-04-02
EP3283110B1 (en) 2022-04-20
HK1250941A1 (en) 2019-01-18
KR102666920B1 (ko) 2024-05-20
JP7212098B2 (ja) 2023-01-24
CN107847590B (zh) 2022-07-26
AU2016248208A1 (en) 2017-11-09
US20210388095A1 (en) 2021-12-16
US12391761B2 (en) 2025-08-19
MX2017013080A (es) 2018-02-09
US20260022181A1 (en) 2026-01-22
RU2017139481A (ru) 2019-05-15
CA2982555A1 (en) 2016-10-20
HK1252009A1 (zh) 2019-05-10
EP4176900A1 (en) 2023-05-10
US20180094065A1 (en) 2018-04-05
US11130814B2 (en) 2021-09-28
SG11201708061TA (en) 2017-10-30
AU2016248208B2 (en) 2022-03-24
KR20180002687A (ko) 2018-01-08
ES2914243T3 (es) 2022-06-08
WO2016168542A1 (en) 2016-10-20
JP2021118710A (ja) 2021-08-12
CN107847590A (zh) 2018-03-27
BR112017022086A2 (pt) 2018-07-03
PL3283110T3 (pl) 2022-06-27
RU2017139481A3 (https=) 2019-09-19
DK3283110T3 (da) 2022-05-23
JP2025163120A (ja) 2025-10-28
JP2018512157A (ja) 2018-05-17

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