JP6861418B2 - ヒトｔ細胞免疫グロブリン及びｉｔｉｍドメイン（ｔｉｇｉｔ）に特異的な抗体 - Google Patents

ヒトｔ細胞免疫グロブリン及びｉｔｉｍドメイン（ｔｉｇｉｔ）に特異的な抗体 Download PDF

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JP6861418B2
JP6861418B2 JP2018511264A JP2018511264A JP6861418B2 JP 6861418 B2 JP6861418 B2 JP 6861418B2 JP 2018511264 A JP2018511264 A JP 2018511264A JP 2018511264 A JP2018511264 A JP 2018511264A JP 6861418 B2 JP6861418 B2 JP 6861418B2
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antibody
sequence
tigit
cancer
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JP2018532383A5 (enExample
JP2018532383A (ja
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マンデルボイム，オファー
エス． カイナン，ノア
エス． カイナン，ノア
ツケルマン，ピンカス
ジョンジク，スティパン
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イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム リミテッド
イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム リミテッド
ユニバーシティー オブ リエカ ファカルティー オブ メディシン
ユニバーシティー オブ リエカ ファカルティー オブ メディシン
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • A—HUMAN NECESSITIES
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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JP2018511264A 2015-09-02 2016-09-01 ヒトｔ細胞免疫グロブリン及びｉｔｉｍドメイン（ｔｉｇｉｔ）に特異的な抗体 Active JP6861418B2 (ja)

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Application Number Priority Date Filing Date Title
US201562213140P 2015-09-02 2015-09-02
US62/213,140 2015-09-02
US201662314427P 2016-03-29 2016-03-29
US62/314,427 2016-03-29
PCT/IL2016/050952 WO2017037707A1 (en) 2015-09-02 2016-09-01 Antibodies specific to human t-cell immunoglobulin and itim domain (tigit)

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JP2018532383A JP2018532383A (ja) 2018-11-08
JP2018532383A5 JP2018532383A5 (enExample) 2019-10-03
JP6861418B2 true JP6861418B2 (ja) 2021-04-28

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US (2) US10946095B2 (enExample)
EP (1) EP3344658B1 (enExample)
JP (1) JP6861418B2 (enExample)
CN (1) CN108137691B (enExample)
CA (1) CA2997130A1 (enExample)
ES (1) ES2924071T3 (enExample)
WO (1) WO2017037707A1 (enExample)

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US20210220472A1 (en) 2021-07-22
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