JP6806413B2 - 多環性ピリドン誘導体およびそのプロドラッグ - Google Patents

多環性ピリドン誘導体およびそのプロドラッグ Download PDF

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JP6806413B2
JP6806413B2 JP2016187212A JP2016187212A JP6806413B2 JP 6806413 B2 JP6806413 B2 JP 6806413B2 JP 2016187212 A JP2016187212 A JP 2016187212A JP 2016187212 A JP2016187212 A JP 2016187212A JP 6806413 B2 JP6806413 B2 JP 6806413B2
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JP2017137291A (ja
JP2017137291A5 (enrdf_load_stackoverflow
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河井　真
真 河井
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Shionogi and Co Ltd
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2016187212A 2016-02-03 2016-09-26 多環性ピリドン誘導体およびそのプロドラッグ Active JP6806413B2 (ja)

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JP2016018772 2016-02-03
JP2016018772 2016-02-03

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JP2020200619A Division JP7095945B2 (ja) 2016-02-03 2020-12-02 多環性ピリドン誘導体およびそのプロドラッグ

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JP2017137291A JP2017137291A (ja) 2017-08-10
JP2017137291A5 JP2017137291A5 (enrdf_load_stackoverflow) 2019-07-18
JP6806413B2 true JP6806413B2 (ja) 2021-01-06

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JP2020200619A Active JP7095945B2 (ja) 2016-02-03 2020-12-02 多環性ピリドン誘導体およびそのプロドラッグ

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Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201708721XA (en) 2015-04-28 2017-11-29 Shionogi & Co Substituted polycyclic pyridone derivative and prodrug thereof
JP6323860B2 (ja) 2015-12-15 2018-05-16 塩野義製薬株式会社 キャップ依存的エンドヌクレアーゼ阻害剤及び抗インフルエンザ薬を組み合わせることを特徴とするインフルエンザ治療用医薬
CR20190123A (es) 2016-08-10 2019-04-30 Shionogi & Co Composiciones farmacéuticas que contienen derivados de piridona policíclicos sustituídos y profármacos de los mismos
AU2018331172B2 (en) * 2017-09-18 2022-12-01 Sunshine Lake Pharma Co., Ltd. Influenza virus replication inhibitor and use thereof
SG11202011447UA (en) * 2018-01-17 2020-12-30 Jiangxi Caishi Pharmaceutical Technology Co Ltd Pyridone derivative, composition and use as antiviral drug thereof
US10596171B2 (en) * 2018-01-22 2020-03-24 Taigen Biotechnology Co., Ltd. Cap-dependent endonuclease inhibitors
CN109956956B (zh) * 2018-05-15 2020-07-07 广东东阳光药业有限公司 一种并环吡啶酮化合物的制备方法
CN108558907B (zh) * 2018-06-01 2019-08-09 海化生命(厦门)科技有限公司 一种关键中间体2的制备方法
JP7307412B2 (ja) 2018-06-27 2023-07-12 国立大学法人北海道大学 多環性カルバモイルピリドン誘導体を含有するアレナウイルス増殖阻害剤
WO2020015669A1 (zh) * 2018-07-17 2020-01-23 南京明德新药研发有限公司 抗流感病毒三并环衍生物
WO2020078401A1 (en) * 2018-10-17 2020-04-23 Sunshine Lake Pharma Co., Ltd. Influenza virus replication inhibitor and uses thereof
CN111410661B (zh) * 2019-01-04 2023-05-05 周雨恬 帽依赖性内切核酸酶抑制剂及其用途
US20220177487A1 (en) * 2019-04-01 2022-06-09 Nikang Therapeutics, Inc. Fused polycyclic pyridone compounds as influenza virus replication inhibitors
RU2720305C1 (ru) * 2019-05-07 2020-04-28 Андрей Александрович Иващенко Замещенный 3,4,12,12а-тетрагидро-1Н-[1,4]оксазино[3,4-c]пиридо[2,1-f] [1,2,4]триазин-6,8-дион, фармацевтическая композиция, способы их получения и применения
CN110105372B (zh) * 2019-06-05 2022-05-10 南京焕然生物科技有限公司 一种r-7-(苄氧基)-四氢-1h-恶嗪并吡啶并-三嗪-6,8-二酮的制备方法
CN112521386B (zh) * 2019-09-19 2023-05-26 周雨恬 具有抗病毒作用的多环吡啶酮化合物及其药物组合和用途
CN111057070A (zh) * 2019-10-30 2020-04-24 浙江工业大学 一种巴洛沙韦关键中间体的合成方法
CN115175913B (zh) * 2019-11-13 2023-11-28 南京知和医药科技有限公司 取代的双三环化合物及其药物组合物和用途
CN115135646B (zh) * 2019-12-23 2024-05-17 石家庄迪斯凯威医药科技有限公司 取代的多环化合物及其药物组合物和用途
CN113045589B (zh) * 2019-12-27 2024-08-23 广东东阳光药业股份有限公司 流感病毒复制抑制剂及其用途
CN112940009A (zh) * 2020-02-03 2021-06-11 南京知和医药科技有限公司 一种磺酸多环化合物及其药物组合物和用途
CN112876510A (zh) * 2020-02-10 2021-06-01 石家庄迪斯凯威医药科技有限公司 一种磷酸酯类多环化合物及其药物组合物和用途
US11351149B2 (en) 2020-09-03 2022-06-07 Pfizer Inc. Nitrile-containing antiviral compounds
CN112409379B (zh) * 2020-09-28 2023-07-28 长沙晶易医药科技股份有限公司 氘代的二氢二苯并硫杂卓化合物以及包含该化合物的药物组合物
CN114907365B (zh) * 2021-02-09 2023-12-01 扬子江药业集团有限公司 一种流感病毒抑制剂及其用途
CN116284048B (zh) * 2023-05-18 2023-08-15 长沙晶易医药科技股份有限公司 一种化合物及其制备方法、药物组合物和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006342115A (ja) * 2005-06-10 2006-12-21 Shionogi & Co Ltd Ｈｉｖインテグラーゼ阻害活性を有する多環性化合物
PL2444400T3 (pl) * 2009-06-15 2018-08-31 Shionogi & Co., Ltd. Podstawiona policykliczna pochodna karbamoilopirydonowa
JP5766690B2 (ja) * 2010-04-12 2015-08-19 塩野義製薬株式会社 インテグラーゼ阻害活性を有するピリドン誘導体
KR101773226B1 (ko) * 2010-09-24 2017-09-12 시오노기세야쿠 가부시키가이샤 치환된 다환성 카르바모일 피리돈 유도체의 프로드러그

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JP2021046425A (ja) 2021-03-25
JP7095945B2 (ja) 2022-07-05

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