JP6804462B2 - 指数関数の底が２より大きい核酸増幅 - Google Patents

指数関数の底が２より大きい核酸増幅 Download PDF

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JP6804462B2
JP6804462B2 JP2017550468A JP2017550468A JP6804462B2 JP 6804462 B2 JP6804462 B2 JP 6804462B2 JP 2017550468 A JP2017550468 A JP 2017550468A JP 2017550468 A JP2017550468 A JP 2017550468A JP 6804462 B2 JP6804462 B2 JP 6804462B2
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sequence
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template
stranded
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ラッセル・ヒグチ
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セファイド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/161—Modifications characterised by incorporating target specific and non-target specific sites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/191—Modifications characterised by incorporating an adaptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/119—Strand displacement amplification [SDA]

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
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  • Microbiology (AREA)
  • Biotechnology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2017550468A 2014-12-15 2015-12-15 指数関数の底が２より大きい核酸増幅 Active JP6804462B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462092102P 2014-12-15 2014-12-15
US62/092,102 2014-12-15
PCT/US2015/065890 WO2016100388A1 (en) 2014-12-15 2015-12-15 Exponential base-greater-than-2 nucleic acid amplification

Publications (3)

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JP2017537658A JP2017537658A (ja) 2017-12-21
JP2017537658A5 JP2017537658A5 (OSRAM) 2019-02-07
JP6804462B2 true JP6804462B2 (ja) 2020-12-23

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JP2017550468A Active JP6804462B2 (ja) 2014-12-15 2015-12-15 指数関数の底が２より大きい核酸増幅

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US (3) US10273534B2 (OSRAM)
EP (1) EP3234188B1 (OSRAM)
JP (1) JP6804462B2 (OSRAM)
CN (2) CN107429292B (OSRAM)
AU (2) AU2015362617B2 (OSRAM)
CA (1) CA2971006C (OSRAM)
DK (1) DK3234188T3 (OSRAM)
ES (1) ES2764975T3 (OSRAM)
HK (1) HK1247255A1 (OSRAM)
PT (1) PT3234188T (OSRAM)
WO (1) WO2016100388A1 (OSRAM)

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WO2019162530A1 (de) * 2018-02-26 2019-08-29 Agct Gmbh Agverfahren zur amplifikation einer nukleinsäure mit verbesserter spezifität
US20210071244A1 (en) * 2018-02-28 2021-03-11 Agct Gmbh Method for the amplification of a nucleic acid with improved specificity
WO2020092134A1 (en) * 2018-10-29 2020-05-07 Cepheid Exponential base-3 nucleic acid amplification with reduced amplification time using nested overlapping primers
AU2021264451A1 (en) * 2020-04-27 2022-12-01 Cepheid Exponential base-3 and greater nucleic acid amplification with cycling probe
US20230250471A1 (en) * 2020-06-23 2023-08-10 HeimBiotek, Inc. Composition for sequential polymerase chain reaction, and gene amplification method using same
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EP4479559A1 (en) * 2022-02-15 2024-12-25 Cepheid Exponential base-greater-than-base 2 nucleic acid amplification using high- and low-tm primers
CN120731275A (zh) * 2023-02-23 2025-09-30 塞弗德公司 去稳定化核苷三磷酸减少扩增子折叠和降低熔解温度的应用

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CA2971006A1 (en) 2016-06-23
AU2015362617B2 (en) 2022-03-03
CA2971006C (en) 2024-05-21
EP3234188B1 (en) 2019-10-23
US20190203266A1 (en) 2019-07-04
CN114369596A (zh) 2022-04-19
PT3234188T (pt) 2020-01-16
CN107429292B (zh) 2021-12-17
AU2015362617A1 (en) 2017-06-29
WO2016100388A1 (en) 2016-06-23
CN107429292A (zh) 2017-12-01
US20180066304A1 (en) 2018-03-08
AU2022203553B2 (en) 2024-08-08
US10273534B2 (en) 2019-04-30
AU2022203553A1 (en) 2022-06-16
ES2764975T3 (es) 2020-06-05
CN114369596B (zh) 2025-07-08
US11028434B2 (en) 2021-06-08
DK3234188T3 (da) 2020-01-20
US20210395797A1 (en) 2021-12-23
HK1247255A1 (zh) 2018-09-21
EP3234188A1 (en) 2017-10-25
US11952621B2 (en) 2024-04-09
JP2017537658A (ja) 2017-12-21

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