CA2971006C - Exponential base-greater-than-2 nucleic acid amplification - Google Patents
Exponential base-greater-than-2 nucleic acid amplification Download PDFInfo
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- CA2971006C CA2971006C CA2971006A CA2971006A CA2971006C CA 2971006 C CA2971006 C CA 2971006C CA 2971006 A CA2971006 A CA 2971006A CA 2971006 A CA2971006 A CA 2971006A CA 2971006 C CA2971006 C CA 2971006C
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/161—Modifications characterised by incorporating target specific and non-target specific sites
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
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- C12Q2525/191—Modifications characterised by incorporating an adaptor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2531/00—Reactions of nucleic acids characterised by
- C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
- C12Q2531/119—Strand displacement amplification [SDA]
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| EP3287528A1 (de) * | 2016-08-25 | 2018-02-28 | AGCT GmbH | Verfahren zur amplifikation von nukleinsäuren und kit zu dessen durchführung |
| US20210071243A1 (en) * | 2018-02-26 | 2021-03-11 | Agct Gmbh | Method for primer extension reaction with improved specificity |
| WO2019162530A1 (de) * | 2018-02-26 | 2019-08-29 | Agct Gmbh | Agverfahren zur amplifikation einer nukleinsäure mit verbesserter spezifität |
| US20210071244A1 (en) * | 2018-02-28 | 2021-03-11 | Agct Gmbh | Method for the amplification of a nucleic acid with improved specificity |
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| AU2021264451A1 (en) * | 2020-04-27 | 2022-12-01 | Cepheid | Exponential base-3 and greater nucleic acid amplification with cycling probe |
| US20230250471A1 (en) * | 2020-06-23 | 2023-08-10 | HeimBiotek, Inc. | Composition for sequential polymerase chain reaction, and gene amplification method using same |
| KR20230124946A (ko) | 2020-12-24 | 2023-08-28 | 인티그레이티드 디엔에이 테크놀로지스 아이엔씨. | 고-충실도 DNA 폴리머라아제를 이용한 rhPCR 기반 앰플리콘시퀀싱에서 프라이머 이량체 및 오프-타겟 증폭을 감소시키는 RNAse H2 돌연변이체 |
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| US5494810A (en) | 1990-05-03 | 1996-02-27 | Cornell Research Foundation, Inc. | Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease |
| WO1995012309A1 (en) | 1993-11-05 | 1995-05-11 | THE BOARD OF TRUSTEES OF LELAND STANFORD, JR. UNIVERSITY: Suite 350 | NUCLEIC ACIDS ENCODING [His?5, Trp7, Tyr8¿]-GnRH PREPROHORMONE AND [Ser8]-GnRH PREPROHORMONE AND THEIR USES |
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| EP2326732A4 (en) * | 2008-08-26 | 2012-11-14 | Fluidigm Corp | TEST METHODS FOR INCREASED SURPLUS OF SAMPLES AND / OR TARGETS |
| EP2432899A1 (en) * | 2009-05-22 | 2012-03-28 | Population Genetics Technologies LTD. | Sorting asymmetrically tagged nucleic acids by selective primer extension |
| CN102559928A (zh) * | 2011-12-28 | 2012-07-11 | 中国海洋大学 | 特异性引物组、包含其的试剂盒、使用方法及检测方法 |
| KR20130107881A (ko) * | 2012-03-23 | 2013-10-02 | 삼성테크윈 주식회사 | 클라미디아 및 임균 유래의 표적 유전자를 동시에 증폭하고 검출하기 위한 멀티 플렉스 키트 및 이를 이용한 진단 방법 |
| US9074249B2 (en) * | 2012-06-04 | 2015-07-07 | New England Biolabs, Inc. | Detection of amplification products |
| JP2016510991A (ja) | 2013-03-11 | 2016-04-14 | エリテックグループ・ベスローテン・フェンノートシャップＥｌｉｔｅｃｈｇｒｏｕｐ Ｂ．Ｖ． | 正確な鎖置換型等温増幅のための方法 |
| PT3234188T (pt) | 2014-12-15 | 2020-01-16 | Cepheid | Amplificação de ácidos nucleicos em base exponencial superior a 2 |
| US20210071243A1 (en) | 2018-02-26 | 2021-03-11 | Agct Gmbh | Method for primer extension reaction with improved specificity |
| WO2020092134A1 (en) | 2018-10-29 | 2020-05-07 | Cepheid | Exponential base-3 nucleic acid amplification with reduced amplification time using nested overlapping primers |
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| AU2015362617B2 (en) | 2022-03-03 |
| EP3234188B1 (en) | 2019-10-23 |
| US20190203266A1 (en) | 2019-07-04 |
| CN114369596A (zh) | 2022-04-19 |
| PT3234188T (pt) | 2020-01-16 |
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| AU2015362617A1 (en) | 2017-06-29 |
| WO2016100388A1 (en) | 2016-06-23 |
| CN107429292A (zh) | 2017-12-01 |
| US20180066304A1 (en) | 2018-03-08 |
| AU2022203553B2 (en) | 2024-08-08 |
| US10273534B2 (en) | 2019-04-30 |
| AU2022203553A1 (en) | 2022-06-16 |
| ES2764975T3 (es) | 2020-06-05 |
| CN114369596B (zh) | 2025-07-08 |
| US11028434B2 (en) | 2021-06-08 |
| DK3234188T3 (da) | 2020-01-20 |
| US20210395797A1 (en) | 2021-12-23 |
| HK1247255A1 (zh) | 2018-09-21 |
| EP3234188A1 (en) | 2017-10-25 |
| US11952621B2 (en) | 2024-04-09 |
| JP2017537658A (ja) | 2017-12-21 |
| JP6804462B2 (ja) | 2020-12-23 |
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