JP6731958B2 - 選択的ｐｙｙ化合物及びその使用 - Google Patents

選択的ｐｙｙ化合物及びその使用 Download PDF

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Publication number
JP6731958B2
JP6731958B2 JP2017564450A JP2017564450A JP6731958B2 JP 6731958 B2 JP6731958 B2 JP 6731958B2 JP 2017564450 A JP2017564450 A JP 2017564450A JP 2017564450 A JP2017564450 A JP 2017564450A JP 6731958 B2 JP6731958 B2 JP 6731958B2
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Prior art keywords
ethoxy
carboxy
amino
hpyy
butanoyl
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Japanese (ja)
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JP2018522843A (ja
JP2018522843A5 (https=
Inventor
セーアン・ウスタゴー
カーステン・ホルト・イェスン
ビアギテ・シュレルプ・ヴルフ
アニカ・サンフリトソン
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Novo Nordisk AS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
JP2017564450A 2015-06-12 2016-06-13 選択的ｐｙｙ化合物及びその使用 Active JP6731958B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15171785 2015-06-12
EP15171785.7 2015-06-12
PCT/EP2016/063429 WO2016198682A1 (en) 2015-06-12 2016-06-13 Selective pyy compounds and uses thereof

Publications (3)

Publication Number Publication Date
JP2018522843A JP2018522843A (ja) 2018-08-16
JP2018522843A5 JP2018522843A5 (https=) 2019-07-11
JP6731958B2 true JP6731958B2 (ja) 2020-07-29

Family

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Family Applications (1)

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JP2017564450A Active JP6731958B2 (ja) 2015-06-12 2016-06-13 選択的ｐｙｙ化合物及びその使用

Country Status (19)

Country Link
US (1) US10005824B2 (https=)
EP (1) EP3307768B1 (https=)
JP (1) JP6731958B2 (https=)
KR (1) KR102476550B1 (https=)
CN (1) CN107849110B (https=)
AR (1) AR104984A1 (https=)
AU (1) AU2016275735B2 (https=)
BR (1) BR112017025108A2 (https=)
CA (1) CA2988500A1 (https=)
ES (1) ES3019234T3 (https=)
IL (1) IL255781B (https=)
MA (1) MA43205A (https=)
MX (1) MX392572B (https=)
MY (1) MY187047A (https=)
RU (1) RU2726777C2 (https=)
SA (1) SA517390445B1 (https=)
TW (1) TWI694082B (https=)
WO (1) WO2016198682A1 (https=)
ZA (1) ZA201707782B (https=)

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EP4180060A1 (en) 2021-11-15 2023-05-17 Adocia Solid compositions comprising a peptide or a protein and an acylated amino acid
WO2023084118A1 (en) 2021-11-15 2023-05-19 Adocia Solid compositions comprising a peptide or a protein and an acylated amino acid
KR20240110876A (ko) * 2021-11-30 2024-07-16 닛산 가가쿠 가부시키가이샤 하이드록시계피산 유도체를 갖는 레지스트 하층막 형성용 조성물
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EP4299071A1 (en) 2022-07-01 2024-01-03 Adocia Compositions comprising a peptide or a protein and an acylated amino acid
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Publication number Publication date
CN107849110A (zh) 2018-03-27
AU2016275735A1 (en) 2017-12-07
EP3307768A1 (en) 2018-04-18
BR112017025108A2 (pt) 2018-07-31
AU2016275735B2 (en) 2020-02-06
CN107849110B (zh) 2021-11-26
IL255781B (en) 2021-10-31
CA2988500A1 (en) 2016-12-15
RU2017145348A (ru) 2019-07-12
MX2017015105A (es) 2018-05-07
KR20180019616A (ko) 2018-02-26
RU2017145348A3 (https=) 2019-09-09
MY187047A (en) 2021-08-27
SA517390445B1 (ar) 2020-12-21
JP2018522843A (ja) 2018-08-16
ES3019234T3 (en) 2025-05-20
ZA201707782B (en) 2019-08-28
IL255781A (en) 2018-04-30
EP3307768C0 (en) 2025-01-29
WO2016198682A1 (en) 2016-12-15
RU2726777C2 (ru) 2020-07-15
TW201710284A (zh) 2017-03-16
EP3307768B1 (en) 2025-01-29
KR102476550B1 (ko) 2022-12-13
US10005824B2 (en) 2018-06-26
TWI694082B (zh) 2020-05-21
AR104984A1 (es) 2017-08-30
MX392572B (es) 2025-03-24
MA43205A (fr) 2018-09-19
US20170313750A1 (en) 2017-11-02

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